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https://www.readbyqxmd.com/read/29052740/short-term-effects-of-the-anti-sea-lice-therapeutant-emamectin-benzoate-on-clam-worms-nereis-virens
#1
G J McBriarty, K A Kidd, L E Burridge
The polychaete Nereis virens occurs commonly in marine sediments, is widely distributed, and is a popular bait species, as well as a potential replacement for wild-caught fish in commercial fish feed preparations. It is being considered as a potential co-extractive species for culture in integrated multi-trophic aquaculture operations. However, it is not known whether pesticides or drugs used to treat sea lice on farmed salmon, such as emamectin benzoate (EB), would adversely affect cultured or wild worms, because these compounds may persist in the environment...
October 20, 2017: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/29051484/high-reactivity-of-deep-biota-under-anthropogenic-co2-injection-into-basalt
#2
Rosalia Trias, Bénédicte Ménez, Paul le Campion, Yvan Zivanovic, Léna Lecourt, Aurélien Lecoeuvre, Philippe Schmitt-Kopplin, Jenny Uhl, Sigurður R Gislason, Helgi A Alfreðsson, Kiflom G Mesfin, Sandra Ó Snæbjörnsdóttir, Edda S Aradóttir, Ingvi Gunnarsson, Juerg M Matter, Martin Stute, Eric H Oelkers, Emmanuelle Gérard
Basalts are recognized as one of the major habitats on Earth, harboring diverse and active microbial populations. Inconsistently, this living component is rarely considered in engineering operations carried out in these environments. This includes carbon capture and storage (CCS) technologies that seek to offset anthropogenic CO2 emissions into the atmosphere by burying this greenhouse gas in the subsurface. Here, we show that deep ecosystems respond quickly to field operations associated with CO2 injections based on a microbiological survey of a basaltic CCS site...
October 20, 2017: Nature Communications
https://www.readbyqxmd.com/read/29027235/low-dose-ct-for-the-detection-and-classification-of-metastatic-liver-lesions-results-of-the-2016-low-dose-ct-grand-challenge
#3
Cynthia H McCollough, Adam C Bartley, Rickey E Carter, Baiyu Chen, Tammy A Drees, Phillip Edwards, David R Holmes, Alice E Huang, Farhana Khan, Shuai Leng, Kyle L McMillan, Gregory J Michalak, Kristina M Nunez, Lifeng Yu, Joel G Fletcher
PURPOSE: Using common datasets, to estimate and compare the diagnostic performance of image-based denoising techniques or iterative reconstruction algorithms for the task of detecting hepatic metastases. METHODS: Datasets from contrast-enhanced CT scans of the liver were provided to participants in an NIH-, AAPM- and Mayo Clinic-sponsored Low Dose CT Grand Challenge. Training data included full-dose and quarter-dose scans of the ACR CT accreditation phantom and 10 patient examinations; both images and projections were provided in the training data...
October 2017: Medical Physics
https://www.readbyqxmd.com/read/29023489/spatiotemporal-variations-in-gene-expression-histology-and-biomechanics-in-an-ovine-model-of-tendinopathy
#4
Sara Biasutti, Andrew Dart, Margaret Smith, Carina Blaker, Elizabeth Clarke, Leo Jeffcott, Christopher Little
Flexor tendinopathy is a common problem affecting humans and animals. Tendon healing is poorly understood and the outcomes of conservative and surgical management are often suboptimal. While often considered a localized injury, recent evidence indicates that in the short term, tendinopathic changes are distributed widely throughout the tendon, remote from the lesion itself. Whether these changes persist throughout healing is unknown. The aim of this study was to document gene expression, histopathological and biomechanical changes that occur throughout the superficial digital flexor tendon (SDFT) up to 16 weeks post-injury, using an ovine surgical model of tendinopathy...
2017: PloS One
https://www.readbyqxmd.com/read/29017457/evaluation-of-a-pulsed-xenon-ultraviolet-disinfection-system-to-decrease-bacterial-contamination-in-operating-rooms
#5
Lynn El Haddad, Shashank S Ghantoji, Mark Stibich, Jason B Fleming, Cindy Segal, Kathy M Ware, Roy F Chemaly
BACKGROUND: Environmental cleanliness is one of the contributing factors for surgical site infections in the operating rooms (ORs). To decrease environmental contamination, pulsed xenon ultraviolet (PX-UV), an easy and safe no-touch disinfection system, is employed in several hospital environments. The positive effect of this technology on environmental decontamination has been observed in patient rooms and ORs during the end-of-day cleaning but so far, no study explored its feasibility between surgical cases in the OR...
October 10, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28987786/a-simple-model-of-the-inner-hair-cell-ribbon-synapse-accounts-for-mammalian-auditory-nerve-fiber-spontaneous-spike-times
#6
Adam J Peterson, Peter Heil
The initial neural encoding of acoustic information occurs by means of spikes in primary auditory afferents. Each mammalian primary auditory afferent (type-I auditory-nerve fiber; ANF) is associated with only one ribbon synapse in one receptor cell (inner hair cell; IHC). The properties of ANF spike trains therefore provide an indirect view of the operation of individual IHC synapses. We showed previously that a point process model of presynaptic vesicle pool depletion and deterministic exponential replenishment, combined with short postsynaptic neural refractoriness, accounts for the interspike interval (ISI) distributions, serial ISI correlations, and spike-count statistics of a population of cat-ANF spontaneous spike trains...
September 15, 2017: Hearing Research
https://www.readbyqxmd.com/read/28981638/long-term-risk-of-cancer-following-ileal-pouch-anal-anastomosis-for-ulcerative-colitis
#7
Anders Mark-Christensen, Rune Erichsen, Søren Brandsborg, Jacob Rosenberg, Niels Qvist, Ole Thorlacius-Ussing, Jens Hillingsø, Jørn Helmut Pachler, Erica Gould Christiansen, Søren Laurberg
Background: The overall risk of cancer following ileal pouch-anal anastomosis [IPAA] is unknown, and pouch cancer surveillance is controversial. We evaluated long-term risk of cancer in a national cohort of patients with ulcerative colitis and IPAA, with emphasis on pouch cancer. Methods: Data on incident cancers were extracted from the national Danish Cancer Registry. Incidence rates for all site-specific cancers were compared between patients with IPAA and a gender- and age-matched comparison cohort from the background population to obtain incidence rate ratios [IRRs]...
August 3, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28977511/towards-enhanced-and-interpretable-clustering-classification-in-integrative-genomics
#8
Yang Young Lu, Jinchi Lv, Jed A Fuhrman, Fengzhu Sun
High-throughput technologies have led to large collections of different types of biological data that provide unprecedented opportunities to unravel molecular heterogeneity of biological processes. Nevertheless, how to jointly explore data from multiple sources into a holistic, biologically meaningful interpretation remains challenging. In this work, we propose a scalable and tuning-free preprocessing framework, Heterogeneity Rescaling Pursuit (Hetero-RP), which weighs important features more highly than less important ones in accord with implicitly existing auxiliary knowledge...
August 30, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28964620/-fasciocutaneous-flap-reliable-by-deep-femoral-artery-perforator-for-the-treatment-of-ischial-pressure-ulcers
#9
L Gebert, F Boucher, A Lari, F Braye, A Mojallal, M Ismaïl
INTRODUCTION: The surgical management of pressure ulcers in the paraplegic or quadriplegic population is marked by the high risk of recurrence in the long-term. In the current era of perforator flaps, newer reconstructive options are available for the management of pressure ulcers, decreasing the need to use the classically described muscular or musculocutaneous locoregional flaps. The coverage of ischial sores described in this article by a pedicled flap based on a deep femoral artery perforator, appears to be an effective first-line reconstructive option for the management of limited size pressure ulcers...
September 27, 2017: Annales de Chirurgie Plastique et Esthétique
https://www.readbyqxmd.com/read/28963868/use-of-bone-grafts-or-modified-bilateral-sagittal-split-osteotomy-technique-in-large-mandibular-advancements-reduces-the-risk-of-persisting-mandibular-inferior-border-defects
#10
Julio Cifuentes, Nicolás Yanine, Daniel Jerez, Ariel Barrera, Jimoh Olubanwo Agbaje, Constantinus Politis
PURPOSE: Healing of the inferior border of the mandible can be compromised in large advancements, leaving an unesthetic defect at the inferior border. The objective of this study was to compare different bilateral sagittal split osteotomy (BSSO) techniques to prevent the incidence of lower border mandibular defects. MATERIALS AND METHODS: The authors undertook a retrospective multicenter cohort study comparing 3 BSSO techniques for advancements greater than 5 mm: traditional non-grafted BSSO (group A), traditional grafted BSSO (group B), and modified BSSO (group C)...
September 11, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28942231/the-folded-postauricular-flap-a-novel-approach-to-reconstruction-of-large-full-thickness-defects-of-the-conchal-bowl
#11
Ansley M Roche, Martha Griffin, Ron Shelton, Mark L Urken
Extensive subtotal full-thickness auriculectomy defects pose a challenge for the reconstructive surgeon. The posterior island flap (PIF), based on the posterior auricular artery, has been described as a reconstructive option for auricular defects, with reports describing a "pull-through" or "revolving door" technique to reconstruct subtotal partial thickness and full thickness auricular defects. These techniques may result in posterior "pinning" of the auricle. This patient is an 87-year-old male who presented after Mohs excision of squamous cell carcinoma of the conchal bowl, which resulted in a 4x4cm subtotal auriculectomy defect...
September 19, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28928329/single-incision-trocar-less-endoscopic-management-of-giant-liver-hydatid-cyst-in-children
#12
Himanshu Acharya, Vikesh Agrawal, Abhishek Tiwari, Dhananjaya Sharma
INTRODUCTION: Laparoscopic management of giant hydatid cyst has limitations such as spillage, poor control, difficulties in suctioning the contents through special ports which are not easily available, difficulty in the obliteration of residual cavity and recurrence. We describe single-incision trocar-less endoscopic (SITE) technique which simplifies enucleation and management of residual cavity. METHOD: Inclusion criteria for these cases were patients having single uncomplicated giant hydatid cyst >5 cm present at the surface of the liver and palpable on clinical examination...
September 20, 2017: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/28920824/baseline-health-and-nutrition-evaluation-of-two-sympatric-nocturnal-lemur-species-avahi-laniger-and-lepilemur-mustelinus-residing-near-an-active-mine-site-at-ambatovy-madagascar
#13
Randall E Junge, Cathy V Williams, Hajanirina Rakotondrainibe, Karine L Mahefarisoa, Tsiky Rajaonarivelo, Charles Faulkner, Vanessa Mass
Extractive industries can have significant impacts on ecosystems through loss of habitat, degradation of water quality, and direct impact on floral and faunal biodiversity. When operations are located in sensitive regions with high biodiversity containing endangered or threatened species, it is possible to minimize impact on the environment by developing programs to scientifically monitor the impact on resident flora and fauna species in the early phases of operation so that effects can be mitigated whenever possible...
September 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28917256/postoperative-stereotactic-body-radiotherapy-for-spinal-metastases
#14
Majed Alghamdi, Chia-Lin Tseng, Sten Myrehaug, Pejman Maralani, Chris Heyn, Hany Soliman, Young Lee, Mark Ruschin, Leodante Da Costa, Victor Yang, Mikki Campbell, Arjun Sahgal
Spine is a common site of metastases in cancer patients. Spine surgery is indicated for select patients, typically those with mechanical instability and/or malignant epidural spinal cord (or cauda equina) compression. Although post-operative conventional palliative external beam radiation therapy has been the standard of care, technical improvements in radiation planning and image-guided radiotherapy have allowed for the application of stereotactic body radiotherapy (SBRT) to the spine. Spine SBRT is intended to ablate residual tumor and optimize local control by delivering several fold greater biologically effective doses...
September 2017: Chinese Clinical Oncology
https://www.readbyqxmd.com/read/28902899/selective-autonomic-stimulation-of-the-av-node-fat-pad-to-control-rapid-post-operative-atrial-arrhythmias
#15
Marco A Mercader, Dingchao He, Aditya C Sharma, Mark C Marchitto, Gregory Trachiotis, Gene A Bornzin, Richard Jonas, Jeffrey P Moak
Junctional ectopic tachycardia (JET) and atrial fibrillation (AF) occur in patients recovering from open-heart surgery (OHS). Pharmacologic treatment is used for the control of post-operative atrial arrhythmias (POAA), but is associated with side effects. There is a need for a reversible, modulated solution to rate control. We propose a non-pharmacologic technique that can modulate AV nodal conduction in a selective fashion. Ten mongrel dogs underwent OHS. Stimulation of the anterior right (AR) and inferior right (IR) fat pad (FP) was done using a 7-pole electrode...
2017: PloS One
https://www.readbyqxmd.com/read/28902876/postoperative-lead-migration-in-deep-brain-stimulation-surgery-incidence-risk-factors-and-clinical-impact
#16
Takashi Morishita, Justin D Hilliard, Michael S Okun, Dan Neal, Kelsey A Nestor, David Peace, Alden A Hozouri, Mark R Davidson, Francis J Bova, Justin M Sporrer, Genko Oyama, Kelly D Foote
INTRODUCTION: Deep brain stimulation (DBS) is an effective treatment for multiple movement disorders and shows substantial promise for the treatment of some neuropsychiatric and other disorders of brain neurocircuitry. Optimal neuroanatomical lead position is a critical determinant of clinical outcomes in DBS surgery. Lead migration, defined as an unintended post-operative displacement of the DBS lead, has been previously reported. Despite several reports, however, there have been no systematic investigations of this issue...
2017: PloS One
https://www.readbyqxmd.com/read/28893445/cost-benefit-analysis-of-different-air-change-rates-in-an-operating-room-environment
#17
Thomas Gormley, Troy A Markel, Howard Jones, Damon Greeley, John Ostojic, James H Clarke, Mark Abkowitz, Jennifer Wagner
BACKGROUND: Hospitals face growing pressure to meet the dual but often competing goals of providing a safe environment while controlling operating costs. Evidence-based data are needed to provide insight for facility management practices to support these goals. METHODS: The quality of the air in 3 operating rooms was measured at different ventilation rates. The energy cost to provide the heating, ventilation, and air conditioning to the rooms was estimated to provide a cost-benefit comparison of the effectiveness of different ventilation rates currently used in the health care industry...
September 8, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28875285/current-status-of-cardiovascular-surgery-in-japan-2013-and-2014-a-report-based-on-the-japan-cardiovascular-surgery-database-5-thoracic-aortic-surgery
#18
REVIEW
Hideyuki Shimizu, Norimichi Hirahara, Noboru Motomura, Hiroaki Miyata, Shinichi Takamoto
BACKGROUND: Although open aortic repair (OAR) is still considered to be a standard treatment for thoracic aortic diseases, the indications for thoracic endovascular treatment (TEVAR)/hybrid aortic repair (HAR) have expanded in recent years. The purpose of this study was to review the current status of treatment of thoracic aortic diseases in Japan. METHODS: Data for 2013 and 2014 concerning surgery for diseases of the thoracic/thoracoabdominal aorta were extracted from the Japan Cardiovascular Surgery Database (JCVSD)...
September 5, 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28870379/esource-for-clinical-trials-implementation-and-evaluation-of-a-standards-based-approach-in-a-real-world-trial
#19
Jean-Francois Ethier, Vasa Curcin, Mark M McGilchrist, Sarah N Lim Choi Keung, Lei Zhao, Anna Andreasson, Piotr Bródka, Radoslaw Michalski, Theodoros N Arvanitis, Nikolaos Mastellos, Anita Burgun, Brendan C Delaney
OBJECTIVE: The Learning Health System (LHS) requires integration of research into routine practice. 'eSource' or embedding clinical trial functionalities into routine electronic health record (EHR) systems has long been put forward as a solution to the rising costs of research. We aimed to create and validate an eSource solution that would be readily extensible as part of a LHS. MATERIALS AND METHODS: The EU FP7 TRANSFoRm project's approach is based on dual modelling, using the Clinical Research Information Model (CRIM) and the Clinical Data Integration Model of meaning (CDIM) to bridge the gap between clinical and research data structures, using the CDISC Operational Data Model (ODM) standard...
October 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/28864100/optimal-stump-management-in-laparoscopic-appendectomy-a-network-meta-analysis-by-the-minimally-invasive-surgery-synthesis-of-interventions-and-outcomes-network
#20
REVIEW
Stavros A Antoniou, Dimitrios Mavridis, Shahab Hajibandeh, Shahin Hajibandeh, George A Antoniou, Ramon Gorter, Mark Tenhagen, Christos Koutras, Rudolph Pointner, George E Chalkiadakis, Frank-Alexander Granderath, George F Fragiadakis, Anastas E Philalithis, Hendrik Jaap Bonjer
BACKGROUND: Laparoscopic appendectomy is the predominant method of treatment of acute appendicitis. There is insufficient evidence on the most effective management of the appendix stump. The aim of this study was to investigate the relative effectiveness and provide a treatment ranking of different options for securing the appendix stump. METHODS: Electronic databases were searched to identify randomized controlled trials comparing ligation methods of the appendix...
August 29, 2017: Surgery
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