keyword
MENU ▼
Read by QxMD icon Read
search

Cost cardiovascular disease utilization

keyword
https://www.readbyqxmd.com/read/29326146/prior-authorization-requirements-for-proprotein-convertase-subtilisin-kexin-type-9-inhibitors-across-us-private-and-public-payers
#1
Jalpa A Doshi, Justin T Puckett, Michael S Parmacek, Daniel J Rader
BACKGROUND: Proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9is) are an innovative treatment option for patients with familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease who require further lowering of low-density lipoprotein cholesterol. However, the high costs of these agents have spurred payers to implement utilization management policies to ensure appropriate use. We examined prior authorization (PA) requirements for PCSK9is across private and public US payers...
January 2018: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/29290177/health-care-resource-utilization-and-costs-among-newly-diagnosed-and-oral-anticoagulant-naive-nonvalvular-atrial-fibrillation-patients-treated-with-dabigatran-or-warfarin-in-the-united-states
#2
Rahul Jain, An-Chen Fu, Jonathan Lim, Cheng Wang, Jessica Elder, Stephen D Sander, Hiangkiat Tan
BACKGROUND: Warfarin has a long history of use to reduce the risk of stroke in patients with atrial fibrillation (AF), but it requires frequent laboratory monitoring to maintain international normalized ratio levels in the therapeutic range. Dabigatran, a novel oral anticoagulant (OAC), has demonstrated efficacy in reducing the risk of stroke and systemic embolism and does not require laboratory monitoring. OBJECTIVE: To compare health care resource utilization (HCRU) and costs of OAC-naive patients newly diagnosed with nonvalvular atrial fibrillation (NVAF), using dabigatran or warfarin...
January 2018: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/29273021/randomised-controlled-trial-to-improve-health-and-reduce-substance-use-in-established-psychosis-impact-cost-effectiveness-of-integrated-psychosocial-health-promotion
#3
Margaret Heslin, Anita Patel, Daniel Stahl, Poonam Gardner-Sood, Manyara Mushore, Shubulade Smith, Kathryn Greenwood, Oluwadamilola Onagbesan, Conan O'Brien, Catherine Fung, Ruth Ohlsen, David Hopkins, Philippa Lowe, Maurice Arbuthnot, Stan Mutatsa, Gill Todd, Anna Kolliakou, John Lally, Brendon Stubbs, Khalida Ismail, Anthony David, Robin Murray, Zerrin Atakan, Fiona Gaughran
BACKGROUND: There is mounting evidence that people with severe mental illness have unhealthy lifestyles, high rates of cardiovascular and metabolic diseases, and greater risk of early mortality. This study aimed to assess the cost-effectiveness of a health promotion intervention seeking to improve physical health and reduce substance use in people with psychosis. METHODS: Participants with a psychotic disorder, aged 18-65 years old and registered on an enhanced care approach programme or equivalent were recruited from community mental health teams in six mental health trusts in England...
December 22, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/29261241/insurance-switching-and-mismatch-between-the-costs-and-benefits-of-new-technologies
#4
David Cutler, Michael Ciarametaro, Genia Long, Noam Kirson, Robert Dubois
OBJECTIVES: Many therapies have immediate costs but delayed benefits. Recent and anticipated transformative therapies may exacerbate these challenges. This study explored whether disconnects between short-term budget impacts and long-term costs and benefits, and among impacts on initial payers, downstream payers, and society, are expected for a range of such therapies and whether they are likely consistent or variable, with implications for potential policy responses. STUDY DESIGN: Modeling...
December 2017: American Journal of Managed Care
https://www.readbyqxmd.com/read/29240038/prevalence-of-hypertension-htn-and-cardiovascular-risk-factors-in-a-hospitalized-pediatric-hemophilia-population
#5
Warren Alperstein, Fernando F Corrales-Medina, Leonardo Tamariz, Ana M Palacio, Joanna A Davis
Improved life expectancy in hemophilia has led to a greater interest in age-related disorders. Hypertension (HTN) as well as cardiovascular disease have been increasingly reported in hemophilic adults but there is currently very limited data in the pediatric population. We conducted a cross-sectional study using data from the 2012 National Health Cost and Utilization Project database to determine the prevalence of HTN and associated cardiovascular risk factors in a hospitalized pediatric hemophilia population, between the ages of 0 to 21 years, in comparison with the general pediatric population...
December 12, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29230625/systemic-lupus-erythematosus-and-the-risk-of-perioperative-major-adverse-cardiovascular-events
#6
Nathaniel R Smilowitz, Gregory Katz, Jill P Buyon, Robert M Clancy, Jeffrey S Berger
Systemic lupus erythematosus (SLE) is a significant risk factor for cardiovascular disease. The relationship between SLE and perioperative cardiovascular risks following non-cardiac surgery is uncertain. We investigated associations between a diagnosis of SLE and outcomes following major non-cardiac surgery in a large national database from the United States. Patients age ≥ 18 years requiring major non-cardiac surgery were identified from Healthcare Cost and Utilization Project's National Inpatient Sample data from 2004 to 2014...
December 11, 2017: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/29219799/-characteristics-and-healthcare-utilization-of-patients-with-highest-costs-of-care
#7
J J G Wammes, M Tanke, W Jonkers, G P Westert, P J van der Wees, P P T Jeurissen
OBJECTIVE: To determine characteristics and healthcare utilization of high-cost patients in the Netherlands. DESIGN: Cross-sectional study, using claim data for 2013 from one Dutch health insurer. Analyses were limited to the curative health system (care that falls under the Health Insurance Act), including voluntary supplementary insurance. METHOD: We established total healthcare costs per beneficiary by summing all claims with a starting date in 2013...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29210031/adjuvant-statin-therapy-for-esophageal-adenocarcinoma-a-cost-utility-analysis
#8
Rebekah Fong Soe Khioe, Chris Skedgel, Andrew Hart, Michael Philip Nelson Lewis, Leo Alexandre
BACKGROUND: Emerging preclinical evidence indicates statins, medications commonly used in the prevention of cardiovascular disease (CVD), inhibit proliferation, promote apoptosis and limit invasiveness of esophageal adenocarcinoma (EAC). Population-based observational data demonstrate statin treatment after diagnosis of EAC is associated with significant reductions in all-cause and cancer-specific mortality. A feasibility study of adjuvant statin therapy following potentially curative resection for EAC has been completed, with planned progression to a full phase III, randomized controlled trial...
December 5, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/29204858/a-retrospective-analysis-of-corticosteroid-utilization-before-initiation-of-biologic-dmards-among-patients-with-rheumatoid-arthritis-in-the-united-states
#9
Christina A Spivey, Jenny Griffith, Cameron Kaplan, Arnold Postlethwaite, Arijit Ganguli, Junling Wang
INTRODUCTION: Understanding the effects of corticosteroid utilization prior to initiation of biologic disease-modifying antirheumatic drugs (DMARDs) can inform decision-makers on the appropriate use of these medications. This study examined treatment patterns and associated burden of corticosteroid utilization before initiation of biologic DMARDs among rheumatoid arthritis (RA) patients. METHODS: A retrospective analysis was conducted of adult RA patients in the US MarketScan Database (2011-2015)...
December 4, 2017: Rheumatology and Therapy
https://www.readbyqxmd.com/read/29203628/predicting-out-of-office-blood-pressure-in-the-clinic-for-the-diagnosis-of-hypertension-in-primary-care-an-economic-evaluation
#10
Mark Monahan, Sue Jowett, Kate Lovibond, Paramjit Gill, Marshall Godwin, Sheila Greenfield, Janet Hanley, F D Richard Hobbs, Una Martin, Jonathan Mant, Brian McKinstry, Bryan Williams, James P Sheppard, Richard J McManus
Clinical guidelines in the United States and United Kingdom recommend that individuals with suspected hypertension should have ambulatory blood pressure (BP) monitoring to confirm the diagnosis. This approach reduces misdiagnosis because of white coat hypertension but will not identify people with masked hypertension who may benefit from treatment. The Predicting Out-of-Office Blood Pressure (PROOF-BP) algorithm predicts masked and white coat hypertension based on patient characteristics and clinic BP, improving the accuracy of diagnosis while limiting subsequent ambulatory BP monitoring...
December 4, 2017: Hypertension
https://www.readbyqxmd.com/read/29198733/virtual-medicine-utilization-of-the-advanced-cardiac-imaging-patient-avatar-for-procedural-planning-and-facilitation
#11
REVIEW
Jerold S Shinbane, Leslie A Saxon
Advances in imaging technology have led to a paradigm shift from planning of cardiovascular procedures and surgeries requiring the actual patient in a "brick and mortar" hospital to utilization of the digitalized patient in the virtual hospital. Cardiovascular computed tomographic angiography (CCTA) and cardiovascular magnetic resonance (CMR) digitalized 3-D patient representation of individual patient anatomy and physiology serves as an avatar allowing for virtual delineation of the most optimal approaches to cardiovascular procedures and surgeries prior to actual hospitalization...
November 16, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/29188745/bariatric-surgery-versus-conservative-management-for-morbidly-obese-patients-in-spain-a-cost-effectiveness-analysis
#12
Raquel Sanchez-Santos, Esther Mariño Padin, Daniel Adam, Oleg Borisenko, Sergio Estevez Fernandez, Ester Carrera Dacosta, Sonia González Fernández, Juan Turnes Vazquez, Juan Carlos Ruiz de Adana, Felipe de la Cruz Vigo
BACKGROUND: We assessed the cost-effectiveness of bariatric surgery (BS) versus conservative management (CM) for treating morbid obesity in Spain. METHODS: We developed a probabilistic Markov model to estimate health outcomes, quality-adjusted life years (QALY), life years gained (LYG), and costs over lifetime and 10-year horizons. Combined common BS procedures were compared with CM. Clinical and utility inputs were obtained from the literature and resource use and costs from local sources (€2017)...
November 30, 2017: Expert Review of Pharmacoeconomics & Outcomes Research
https://www.readbyqxmd.com/read/29187011/noncardiovascular-disease-and-critical-care-delivery-in-a-contemporary-cardiac-and-medical-intensive-care-unit
#13
Michael Goldfarb, Sean van Diepen, Mark Liszkowski, Jacob C Jentzer, Isabel Pedraza, Bojan Cercek
BACKGROUND: Noncardiovascular comorbidities and critical illness are increasing in cardiovascular intensive care units (CICUs). There are limited data comparing critical care delivery, resource utilization, and costs between contemporary CICUs and medical intensive care units (MICUs). METHODS: All CICU (n = 6967; 22 748 patient-days) and MICU (n = 10 892; 39 211 patient-days) admissions to Cedars-Sinai Medical Center, a tertiary care academic medical center, between January 2011 and December 2016 were reviewed...
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/29181773/budget-impact-analysis-of-pcsk9-inhibitors-for-the-management-of-adult-patients-with-heterozygous-familial-hypercholesterolemia-or-clinical-atherosclerotic-cardiovascular-disease
#14
Usha G Mallya, Susan H Boklage, Andrew Koren, Thomas E Delea, C Daniel Mullins
OBJECTIVE: The aim of this study was to assess the budget impact of introducing the proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9i) alirocumab and evolocumab to market for the treatment of adults with heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular (CV) disease requiring additional lowering of low-density lipoprotein cholesterol (LDL-C). METHODS: A 3-year model estimated the costs of lipid-modifying therapy (LMT) and CV events to a hypothetical US health plan of 1 million members, comparing two scenarios-with and without the availability of PCSK9i as add-on therapy to statins...
November 27, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/29153116/community-guide-cardiovascular-disease-economic-reviews-tailoring-methods-to-ensure-utility-of-findings
#15
Sajal K Chattopadhyay, Verughese Jacob, Shawna L Mercer, David P Hopkins, Randy W Elder, Christopher D Jones
The Community Preventive Services Task Force recommended five interventions for cardiovascular disease prevention between 2012 and 2015. Systematic economic reviews of these interventions faced challenges that made it difficult to generate meaningful policy and programmatic conclusions. This paper describes the methods used to assess, synthesize, and evaluate the economic evidence to generate reliable and useful economic conclusions and address the comparability of economic findings across interventions. Specifically, steps were taken to assess completeness of data and identify the components and drivers of cost and benefit...
December 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29151496/cost-effectiveness-analysis-of-cardiovascular-disease-treatment-in-japan
#16
Satoshi Kodera, Arihiro Kiyosue, Jiro Ando, Hiroshi Akazawa, Hiroyuki Morita, Masafumi Watanabe, Issei Komuro
The quality-adjusted life year (QALY) and incremental cost-effectiveness ratio (ICER) are important concepts in cost-effectiveness analysis, which is becoming increasingly important in Japan. QALY is used to estimate quality of life (QOL) and life years, and can be used to compare the efficacies of cancer and cardiovascular treatments. ICER is defined as the difference in cost between treatments divided by the difference in their effects, with a smaller ICER indicating better cost-effectiveness. Here, we present a review of cost-effectiveness analyses in Japan as well other countries...
November 17, 2017: International Heart Journal
https://www.readbyqxmd.com/read/29106978/coaching-patients-saves-lives-and-money
#17
Joshua Byrnes, Thomas Elliott, Margarite J Vale, Michael V Jelinek, Paul Scuffham
Background The Coaching on Achieving Cardiovascular Health (COACH) Program has been proven to improve biomedical and lifestyle cardiovascular disease (CVD) risk factors. The objective of this study was to evaluate the long term impact of The COACH Program on overall survival, hospital utilization and costs from the perspective of a private health insurer (payor), in patients with CVD. Methods A prospective parallel-group case-control study design with controls randomly matched to patients based on propensity score...
October 26, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/29102035/impact-of-hypothyroidism-on-occurrence-and-outcome-of-acute-coronary-syndrome-from-the-national-inpatient-sample
#18
Rashmi Dhital, Sijan Basnet, Dilli Ram Poudel
Thyroid hormones have a profound effect on cardiovascular physiology. We utilized a large national inpatient database in the United States (National Inpatient Sample) to study hypothyroidism in relation to the prevalence of coronary heart disease (CHD) and its impact on outcomes (mortality, the length of stay, and hospitalization cost) in the acute coronary syndrome (ACS) subgroup of CHD patients. We found that although hypothyroidism has an increased association with CHD (odds ratio [OR] 1.11, 95% confidence interval [CI] 1...
September 19, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28972923/medicaid-insurance-as-primary-payer-predicts-increased-mortality-after-total-hip-replacement-in-the-state-inpatient-databases-of-california-florida-and-new-york
#19
Hannah F Xu, Robert S White, Dahniel L Sastow, Michael H Andreae, Licia K Gaber-Baylis, Zachary A Turnbull
STUDY OBJECTIVE: To confirm the relationship between primary payer status as a predictor of increased perioperative risks and post-operative outcomes after total hip replacements. DESIGN: Retrospective cohort study. SETTING: Administrative database study using 2007-2011 data from California, Florida, and New York from the State Inpatient Databases (SID), Healthcare Cost and Utilization Project, Agency for Healthcare Research and Quality. PATIENTS: 295,572 patients age≥18years old who underwent total hip replacement with non-missing insurance data were collected, using International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) diagnoses and procedures code (ICD-9-CM code 81...
December 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/28963100/meditation-and-cardiovascular-risk-reduction-a-scientific-statement-from-the-american-heart-association
#20
Glenn N Levine, Richard A Lange, C Noel Bairey-Merz, Richard J Davidson, Kenneth Jamerson, Puja K Mehta, Erin D Michos, Keith Norris, Indranill Basu Ray, Karen L Saban, Tina Shah, Richard Stein, Sidney C Smith
Despite numerous advances in the prevention and treatment of atherosclerosis, cardiovascular disease remains a leading cause of morbidity and mortality. Novel and inexpensive interventions that can contribute to the primary and secondary prevention of cardiovascular disease are of interest. Numerous studies have reported on the benefits of meditation. Meditation instruction and practice is widely accessible and inexpensive and may thus be a potential attractive cost-effective adjunct to more traditional medical therapies...
September 28, 2017: Journal of the American Heart Association
keyword
keyword
41499
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"