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Medication synchronization adherence

David F Blackburn, David Tran, Courtney Quiring
OBJECTIVES: To describe medication adherence by the proportion of days covered before and after enrollment in a refill synchronization program. METHODS: We conducted a retrospective analysis of medication adherence in 2 pharmacies offering a refill synchronization program. The study population consisted of individuals who received 2 or more medications from any of 15 predefined medication classes within 6 months of enrollment in the synchronization program. Medication adherence and refill consolidation were measured over 6 months before and after enrollment...
October 5, 2016: Journal of the American Pharmacists Association: JAPhA
Julie A Patterson, David A Holdford, Kunai Saxena
OBJECTIVES: To evaluate the cost-benefit of appointment-based medication synchronization (ABMS) offered in community pharmacies for patients taking chronic medications to prevent negative outcomes associated with hyperlipidemia, hypertension, and diabetes. STUDY DESIGN: Decision-tree analysis based on published literature and publicly available data. METHODS: Program benefits were based on linking published findings of improvements in medication adherence due to the implementation of an ABMS program to a claims-based study of disease-related medical costs associated with different levels of adherence...
September 2016: American Journal of Managed Care
Mohammad Hosseini, Yu Jiang, Poliang Wu, Richard B Berlin, Shangping Ren, Lui Sha
There is a great divide between rural and urban areas, particularly in medical emergency care. Although medical best practice guidelines exist and are in hospital handbooks, they are often lengthy and difficult to apply clinically. The challenges are exaggerated for doctors in rural areas and emergency medical technicians (EMT) during patient transport. In this paper, we propose the concept of distributed executable medical best practice guidance systems to assist adherence to best practice from the time that a patient first presents at a rural hospital, through diagnosis and ambulance transfer to arrival and treatment at a regional tertiary hospital center...
November 2016: Journal of Medical Systems
Jalpa A Doshi, Raymond Lim, Pengxiang Li, Peinie P Young, Victor F Lawnicki, Joseph J State, Andrea B Troxel, Kevin G Volpp
Synchronizing medication refills-renewing all medications at the same time from the same pharmacy-is an increasingly popular strategy to improve adherence to medication regimens, but there has been little research regarding its effectiveness. In light of increasing policy interest, we evaluated the impact of a pilot refill synchronization program implemented by a large national insurer. A random sample of Medicare Advantage patients receiving mail-order refills for common maintenance medications (antihypertensive, lipid-lowering, or antidiabetic agents) were invited to join the program and followed for twelve months...
August 1, 2016: Health Affairs
Rebecca Burkholder, Elaine Linn
Millions of Americans either fail to take the full course of prescribed medication or they take it incorrectly. The problem is particularly serious for people with cardiovascular disease, respiratory disease, and diabetes, and for racially and ethnically diverse populations. The (U.S.) National Consumers League through its Script Your Future medication adherence awareness campaign presented the conference "So Simple, So Hard: Taking Medications as Directed", convening health care professionals, community health workers, consumer and patient advocates, researchers, industry representatives, public agencies, and policymakers...
January 2017: Research in Social & Administrative Pharmacy: RSAP
Alexis A Krumme, Danielle L Isaman, Samuel F Stolpe, Samantha Dougherty, Niteesh K Choudhry
OBJECTIVES: The burden of visiting pharmacies to fill medications is a central contributor to nonadherence to maintenance medications. Recently, pharmacies have begun offering services that align prescription fill dates to allow patients to pick up all medications on a single visit. We evaluated the prevalence and structure of synchronization programs and evidence of their impact on adherence and clinical outcomes. STUDY DESIGN: Mixed-methods approach consisting of semi-structured interviews, data from surveillance activities, and a systematic literature review...
March 2016: American Journal of Managed Care
Scott V Monte, Sarah N Passafiume, Wesley D Kufel, Patrick Comerford, Dean P Trzewieczynski, Kenneth Andrus, Peter M Brody
OBJECTIVE: To provide experience on the methods and costs for delivering a large-scale community pharmacist home visit service. SETTING: Independent urban community pharmacy, Buffalo, NY. PRACTICE DESCRIPTION: Mobile Pharmacy Solutions provides traditional community pharmacy walk-in service and a suite of clinically oriented services, including outbound adherence calls linked to home delivery, payment planning, medication refill synchronization, adherence packaging, and pharmacist home visits...
January 2016: Journal of the American Pharmacists Association: JAPhA
Sebastian Böing, Winfried J Randerath
Chronic hypoventilation affects patients with disorders on any level of the respiratory system. The generation of respiratory impulses can be impaired in congenital disorders, such as central congenital alveolar hypoventilation, in alterations of the brain stem or complex diseases like obesity hypoventilation. The translation of the impulses via spinal cord and nerves to the respiratory muscles can be impaired in neurological diseases. Thoraco-skeletal or muscular diseases may inhibit the execution of the impulses...
August 2015: Journal of Thoracic Disease
Meagen Rosenthal, Erin Holmes, Benjamin Banahan
Although the literature has demonstrated positive patient outcomes from medication therapy management (MTM), implementing it in community pharmacy continues to be met with significant barriers. To make MTM implementation more attainable, scalable, and sustainable in community pharmacies, this paper puts out a call for the need to identify the proportion of patients who clinically qualify for various levels of intensity of MTM services. This paper presents three proposed levels of MTM: adherence management (lowest level of MTM intensity), interventions on drug-related problems (mid-level MTM intensity), and disease state management (highest level of intensity)...
May 2016: Research in Social & Administrative Pharmacy: RSAP
Matthew Witry
No abstract text is available yet for this article.
August 2015: Journal of Managed Care & Specialty Pharmacy
David Holdford, Kunal Saxena
BACKGROUND: Appointment-based medication synchronization (ABMS) has been associated with greater patient adherence and persistence when patients begin taking chronic medications. It is not known whether similar results will be seen for patients who have been taking chronic medications for 6 months or more. OBJECTIVE: To compare the impact of a community pharmacy chain's ABMS program on medication adherence and persistence of existing users of chronic medications with individuals who are not enrolled in the program...
August 2015: Journal of Managed Care & Specialty Pharmacy
Alessandro Proclemer, Massimo Zecchin, Maurizio Lunati, Luca Rebellato, Marco Ghidina, Giulia Bianco, Emanuela Bernardelli, Elsa Pucher, Dario Gregori
BACKGROUND: The pacemaker (PM) and implantable cardioverter-defibrillator (ICD) Registry of the Italian Association of Arrhythmology and Cardiac Pacing (AIAC) monitors the main epidemiological data in real-world practice. The survey for the 2012 activity collects information about demographics, clinical characteristics, main indications for PM/ICD therapy and device types from the Italian collaborating centers. METHODS: The Registry collects prospectively national PM and ICD implantation activity on the basis of European cards...
November 2013: Giornale Italiano di Cardiologia
David A Holdford, Timothy J Inocencio
OBJECTIVE: To assess the impact of an appointment-based medication synchronization (ABMS) program on medication adherence and persistence with chronic medications. DESIGN Quasiexperimental study in which study patients were matched with control patients. SETTING: Rural pharmacies in the Midwestern United States between June 30, 2011, and October 31, 2012. PATIENTS: Individuals receiving at least two refills for one of six categories of medications to treat chronic diseases (i...
November 2013: Journal of the American Pharmacists Association: JAPhA
Liwu G Chen, Paul T Finger, Elona Dhrami-Gavazi
PURPOSE: To present a case series of peripheral pigmented placoid corneal endotheliopathy (PPPCE). METHODS: A retrospective chart review of patient demographics, medical histories, and clinical characteristics was performed. Examinations included the following specialized imaging modalities: slit-lamp photography, gonioscopy, high-frequency ultrasound biomicroscopy, and anterior segment ocular coherence tomography. A PubMed and multiple corneal textbook literature search using the key words cornea, pigment, plaque, and endothelium revealed that no similar cases were reported...
November 2013: Cornea
Kate Traynor
No abstract text is available yet for this article.
July 15, 2013: American Journal of Health-system Pharmacy: AJHP
Alexander Ross, Humaira Jami, Heather A Young, Richard Katz
BACKGROUND: Medication nonadherence is associated with higher cost of care and poor outcomes. Medication refill consolidation (synchronization of refill dates for patients on multiple drugs) is an important component of regimen complexity. We presumed that Medicaid patients with a 30-day medication supply limit would have significant difficulty with refill consolidation. We evaluated regimen complexity and refill consolidation in relation to medication adherence in the Medicaid population...
October 2013: Journal of Primary Care & Community Health
Carlo Dani, Cecilia Bresci, Gianluca Lista, Claudio Martano, Francesco Messina, Claudio Migliori, Giovanni Vento
We carried out a survey of current practices of neonatal respiratory support in neonatal intensive care units (NICUs) in Italy with the aim of comparing the current reality with evidence from the literature. We sent a questionnaire by email to the 103 level III neonatal units in Italy. There was a 61 % (73/120) response rate to the questionnaire. We found that synchronized intermittent positive pressure ventilation is mostly used in infants in the acute phase of respiratory distress syndrome (RDS), while the majority of the units prefer volume-targeted ventilation for those in the weaning phase...
March 2013: European Journal of Pediatrics
Efstathios Theodorou, Robert Forman
In oocyte donation cycles where hormone replacement is given to recipients, progesterone administration is necessary to induce the luteal phase and synchronize the endometrium with the embryo stage. Most studies suggest that 5-7 days of progesterone are needed to prepare the endometrium for a day-5 embryo transfer and provide optimal implantation rate. This paper reports a case where an agonadal oocyte recipient received only 2 days of progesterone prior to the embryo transfer of a day-5 embryo. She subsequently had a clinical pregnancy and a live birth...
October 2012: Reproductive Biomedicine Online
Sicco A Bus, Roelof Waaijman, Frans Nollet
OBJECTIVE: To assess the validity and feasibility of a new temperature-based adherence monitor to measure footwear use. DESIGN: Observational study. SETTING: University medical center and participants' homes. PARTICIPANTS: Convenience sample of healthy subjects (n=11) and neuropathic diabetic patients at high risk for foot ulceration (n=14). INTERVENTIONS: In healthy subjects, the validity of the in-shoe attached adherence monitor was investigated by comparing its registrations of donning and doffing of footwear during 7 days to an accurately kept log registration...
November 2012: Archives of Physical Medicine and Rehabilitation
Robert H Schmicker, Brian G Leroux, Gena K Sears, Ian Stiell, Laurie J Morrison, Tom P Aufderheide, Ray Fowler, Rusty Lowe, Stanley Morrow, Ed Plumlee, Sheldon Cheskes
BACKGROUND: Low compliance to randomized nondrug interventions can affect treatment estimates of clinical trials. Cluster-randomized crossover may be appropriate for increasing compliance in the out-of-hospital cardiac arrest setting. PURPOSE: The purpose was to determine whether the elapsed time from start of a nonblinded treatment period to episode enrollment date in a cluster-randomized crossover trial is associated with compliance to either a period of brief cardiopulmonary resuscitation (CPR) with electrocardiogram (ECG) rhythm analysis or a period of longer CPR with a delayed ECG rhythm analysis in patients with out-of-hospital cardiac arrest...
June 2012: Clinical Trials: Journal of the Society for Clinical Trials
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