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https://www.readbyqxmd.com/read/29788066/lipid-changes-and-tolerability-in-a-cohort-of-adult-hiv-infected-patients-who-switched-to-rilpivirine-emtricitabine-tenofovir-due-to-intolerance-to-previous-combination-art-the-pro-str-study
#1
A Ocampo, P Domingo, P Fernández, J Diz, J R Barberá, M A Sepúlveda, X Salgado, M Rodriguez, J Santos, M Yzusqui, M I Mayorga, J F Lorenzo, A Bahamonde, P Bachiller, E Martínez, N Rozas, C Torres, A Muñoz, A Casado, D Podzamczer
Objectives: To analyse lipid changes and tolerability in a cohort of HIV-infected patients who switched their antiretroviral regimens to rilpivirine/emtricitabine/tenofovir (RPV/FTC/TDF) in a real-world setting. Methods: PRO-STR is a 48 week prospective observational post-authorization study in 25 hospitals. Patients with a viral load <1000 copies/mL, receiving at least 12 months of combination ART (cART), with constant posology for at least the prior 3 months, were categorized according to previous treatment [NNRTI or ritonavir-boosted PI (PI/r)]...
May 16, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29778558/successful-kidney-transplant-with-eculizumab-thymoglobulin-and-belatacept-therapy-in-a-highly-sensitised-patient-with-atypical-haemolytic-uraemic-syndrome-due-to-factor-h-mutation
#2
John Fredy Nieto-Ríos, Mónica Zuluaga-Quintero, Diana Carolina Bello-Márquez, Arbey Aristizabal-Alzate, Catalina Ocampo-Kohn, Lina María Serna-Higuita, Lina Arias, Gustavo Zuluaga-Valencia
Atypical haemolytic uremic syndrome is a disease caused by complement regulation abnormalities that generally progresses to chronic end-stage renal disease with a high rate of recurrence in kidney transplantation and a high risk of graft loss. Anti-complement therapy has improved the prognosis of these patients, achieving disease remission in most cases, increasing the likelihood of a successful kidney transplant and increasing patient and graft survival. Drugs with low risk of induction of thrombotic microangiopathies such as belatacept and mycophenolate have also been used with satisfactory results...
May 16, 2018: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/29760765/an-improved-method-for-agrobacterium-rhizogenes-mediated-transformation-of-tomato-suitable-for-the-study-of-arbuscular-mycorrhizal-symbiosis
#3
Tania Ho-Plágaro, Raúl Huertas, María I Tamayo-Navarrete, Juan A Ocampo, José M García-Garrido
Background: Solanum lycopersicum , an economically important crop grown worldwide, has been used as a model for the study of arbuscular mycorrhizal (AM) symbiosis in non-legume plants for several years and several cDNA array hybridization studies have revealed specific transcriptomic profiles of mycorrhizal tomato roots. However, a method to easily screen candidate genes which could play an important role during tomato mycorrhization is required. Results: We have developed an optimized procedure for composite tomato plant obtaining achieved through Agrobacterium rhizogenes -mediated transformation...
2018: Plant Methods
https://www.readbyqxmd.com/read/29756958/poor-breastfeeding-complementary-feeding-and-dietary-diversity-in-children-and-their-relationship-with-stunting-in-rural-communities
#4
Jessica Zaragoza Cortes, Luis Eduardo Trejo Osti, Moisés Ocampo Torres, Laura Maldonado Vargas, Alicia Arminda Ortiz Gress
INTRODUCTION: stunted growth is the most common manifestation of malnutrition in México. Breastfeeding, adequate introduction of complementary feeding and dietary diversity can avoid this. OBJECTIVE: to characterize the feeding practices in children 1-24 months of age in rural communities of Hidalgo and define their relationship with stunting. METHODS: a 24-hour recall was used to obtain information. Z-scores for length-for-age (ZLA), complementary feeding (CF) and minimal dietary diversity (MDD) were determined...
February 27, 2018: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29754706/ethics-committees-and-mental-health
#5
Carlos Enrique Yepes Delgado, Andrea Ocampo Montoya
Although research processes are covered by the objectivity of science, they are still influenced by the interests of those who conduct them. This is why high level committees have been tasked with defining the scope of the studies and performing a thorough assessment of them, since these imply great dilemmas. This premise leads to the emergence of Ethics Committees, where liaison psychiatry has an important place due to its communication abilities and knowledge of the human behavior. This paper attempts to provide some observations to take into account when discussing the link between ethics and mental health...
April 2018: Revista Colombiana de Psiquiatría
https://www.readbyqxmd.com/read/29742195/longitudinal-melanonychia-biopsy-what-not-to-do
#6
Jorge Ocampo-Garza, Joana Mendes Bretas, Daiane Matana, Paula Jacomini Sobral, Curtis T Thompson, Martin Zaiac, Antonella Tosti
The nail matrix biopsy is an important technique in confirming or excluding a diagnosis of melanoma in a patient with longitudinal melanonychia. Dermatologists are the first-line diagnosticians for these pigmented lesions of the nail unit, however, for different reasons, some are reluctant to perform a nail biopsy. This case demonstrates how a poor biopsy technique resulted in a misdiagnosis in a patient with melanoma in situ. J Drugs Dermatol. 2018;17(5):587-588.
May 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29735288/clinical-practice-guidelines-for-the-treatment-of-systemic-lupus-erythematosus-by-the-mexican-college-of-rheumatology
#7
Daniel Xibillé-Friedmann, Marcela Pérez-Rodríguez, Sandra Carrillo-Vázquez, Everardo Álvarez-Hernández, Francisco Javier Aceves, Mario C Ocampo-Torres, Conrado García-García, José Luis García-Figueroa, Javier Merayo-Chalico, Ana Barrera-Vargas, Margarita Portela-Hernández, Sandra Sicsik, Lilia Andrade-Ortega, Víctor Manuel Rosales-Don Pablo, Aline Martínez, Pilar Prieto-Seyffert, Mario Pérez-Cristóbal, Miguel Ángel Saavedra, Zully Castro-Colín, Azucena Ramos, Gabriela Huerta-Sil, María Fernanda Hernández-Cabrera, Luis Javier Jara, Leonardo Limón-Camacho, Lizbet Tinajero-Nieto, Leonor A Barile-Fabris
There are national and international clinical practice guidelines for systemic lupus erythematosus treatment. Nonetheless, most of them are not designed for the Mexican population or are devoted only to the treatment of certain disease manifestations, like lupus nephritis, or are designed for some physiological state like pregnancy. The Mexican College of Rheumatology aimed to create clinical practice guidelines that included the majority of the manifestations of systemic lupus erythematosus, and also incorporated guidelines in controversial situations like vaccination and the perioperative period...
May 4, 2018: Reumatología Clinica
https://www.readbyqxmd.com/read/29701207/new-highlights-on-the-health-improving-effects-of-sulforaphane
#8
REVIEW
Alfredo Briones-Herrera, Dianelena Eugenio-Pérez, Jazmin Gabriela Reyes-Ocampo, Susana Rivera-Mancía, José Pedraza-Chaverri
In this paper, we review recent evidence about the beneficial effects of sulforaphane (SFN), which is the most studied member of isothiocyanates, on both in vivo and in vitro models of different diseases, mainly diabetes and cancer. The role of SFN on oxidative stress, inflammation, and metabolism is discussed, with emphasis on those nuclear factor E2-related factor 2 (Nrf2) pathway-mediated mechanisms. In the case of the anti-inflammatory effects of SFN, the point of convergence seems to be the downregulation of the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), with the consequent amelioration of other pathogenic processes such as hypertrophy and fibrosis...
April 27, 2018: Food & Function
https://www.readbyqxmd.com/read/29692940/lymph-drainage-of-posttraumatic-edema-of-lower-limbs
#9
Ana Carolina Pereira de Godoy, Rodrigo Ocampos Troitino, Maria de Fátima Guerreiro Godoy, José Maria Pereira de Godoy
Objective: The present study was aimed at evaluating the use of mechanical and manual lymphatic therapy as a treatment for lymphedema resulting from orthopedic surgery that became painful after an episode of erysipelas. Case Report: A 70-year-old male patient suffered direct trauma resulting in a compound fracture of the tibia and fibula of the left leg. He was treated with an external fixator for four months followed by plaster cast immobilization for three weeks...
2018: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/29680064/fermented-non-digestible-fraction-from-combined-nixtamalized-corn-zea-mays-l-cooked-common-bean-phaseolus-vulgaris-l-chips-modulate-anti-inflammatory-markers-on-raw-264-7-macrophages
#10
I Luzardo-Ocampo, R Campos-Vega, M L Cuellar-Nuñez, P A Vázquez-Landaverde, L Mojica, J A Acosta-Gallegos, G Loarca-Piña
Chronic non-communicable diseases (NCDs) are low-level inflammation processes affected by several factors including diet. It has been reported that mixed whole grain and legume consumption, e.g. corn and common bean, might be a beneficial combination due to its content of bioactive compounds. A considerable amount would be retained in the non-digestible fraction (NDF), reaching the colon, where microbiota produce short-chain fatty acids (SCFAs) and phenolic compounds (PC) with known anti-inflammatory effect...
September 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29675624/tuberculosis-and-systemic-lupus-erythematosus-a-case-control-study-in-mexico-city
#11
Pedro Torres-González, Juanita Romero-Díaz, Miguel Enrique Cervera-Hernández, Mario Ocampo-Torres, Luis Gerardo Chaires-Garza, Ernesto Alejandro Lastiri-González, Yemil Atisha-Fregoso, Miriam Bobadilla-Del-Valle, Alfredo Ponce-de-León, José Sifuentes-Osornio
To determine, among systemic lupus erythematosus patients, factors associated with active tuberculosis. We performed a case-control study, in a tertiary-care center in Mexico City. We defined cases as systemic lupus erythematosus patients with active tuberculosis and matched them 1:1 with systemic lupus erythematosus patients without tuberculosis (controls) by age, date of systemic lupus erythematosus diagnosis, and disease duration. We analyzed clinical variables, lupus disease activity (SLEDAI-2K), and accumulated damage (SLICC/ARC-DI)...
April 20, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29675512/bonding-performance-of-universal-adhesives-to-eroded-dentin
#12
Fabiana S F Siqueira, Andres Millan Cardenas, Jessica Bedoya Ocampo, Viviane Hass, Matheus Coelho Bandeca, João Carlos Gomes, Alessandra Reis, Alessandro D Loguercio
PURPOSE: To evaluate the microtensile bond strength (μTBS) and nanoleakage (NL) of several universal adhesives to eroded dentin (ED), using etch-and-rinse (ER) or self-etch (SE) strategies, and to characterize the surface using two pH cycling models to erode dentin (citric acid and a soft drink). MATERIALS AND METHODS: Molars were eroded either by soft-drink or citric acid cycling, or were left untreated as control (SD). For each surface, the following adhesives were applied: 1...
April 19, 2018: Journal of Adhesive Dentistry
https://www.readbyqxmd.com/read/29668131/-severe-hypoxemic-respiratory-failure-caused-by-pneumocystis-jirovecii-in-a-late-kidney-transplant-recipient
#13
John Fredy Nieto-Ríos, Mónica Zuluaga-Quintero, Arbey Aristizábal-Alzate, Catalina Ocampo-Kohn, Lina María Serna-Higuita, Isabel Cristina Ramírez-Sánchez, Gustavo Adolfo Zuluaga-Valencia
Pneumonia caused by Pneumocystis jirovecii is an uncommon infection in kidney transplant patients that can have an acute and rapid progression to respiratory failure and death. The period of greatest risk occurs in the first six months after the transplant, and it relates to the high doses of immunosuppression drugs required by patients. However, it may occur late, associated with the suspension of prophylaxis with trimethoprim-sulfamethoxazole.We present two cases of renal transplant patients who had severe hypoxemic respiratory failure due to P...
March 15, 2018: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/29660123/a-new-species-of-hemibrycon-characiformes-characidae-stevardiinae-from-the-upper-magdalena-river-basin-in-colombia
#14
J E García-Melo, J G Albornoz-Garzón, L J García-Melo, F A Villa-Navarro, J A Maldonado-Ocampo
Hemibrycon iqueima sp. nov., is described from small streams in the Magdalena drainage at the foothills of the western slope of the Eastern Cordillera of the Colombian Andes, Suarez municipality, Tolima Department, Colombia. The new species is distinguished from its congeners in the Magdalena-Cauca River basin by a combination of characters related to snout-anal-fin origin length, head length, dorsal-pectoral fin distance, dorsal-fin-hypural distance, postorbital distance, orbital diameter, snout length, number of total vertebrae, pre-dorsal scales, scale rows between anal-fin origin and lateral line, number of branched rays of the anal fin, maxillary teeth number and number and arrangement of hooks on the branched rays of the pectoral and dorsal fins...
April 16, 2018: Journal of Fish Biology
https://www.readbyqxmd.com/read/29659780/health-outcomes-for-clients-of-needle-and-syringe-programs-in-prisons
#15
Jeffrey V Lazarus, Kelly Safreed-Harmon, Kristina L Hetherington, Daniel J Bromberg, Denise Ocampo, Niels Graf, Anna Dichtl, Heino Stöver, Hans Wolff
High levels of drug dependence have been observed in the prison population globally, and the sharing of injecting drug equipment in prisons has contributed to higher prevalence of bloodborne diseases in prisoners than in the general population. Few prison needle and syringe programs (PNSPs) exist. We conducted a systematic review to assess evidence regarding health outcomes of PNSPs. We searched peer-reviewed databases for data relating to needle and syringe programs in prisons. The search methodology was conducted in accordance with accepted guidelines...
April 12, 2018: Epidemiologic Reviews
https://www.readbyqxmd.com/read/29659365/-association-between-diabetic-ketoacidosis-and-acromegaly
#16
Paloma Ocampo, Juan Manuel Duarte, Ricardo Barcia, Cecilia Arévalo
Diabetes mellitus occurs in nearly 10% of patients with acromegaly and is secondary to insulin resistance caused by high levels of growth hormone. Diabetes ketoacidosis has been described as a rare complication of acromegaly, resulting from a relative insulin deficiency caused by growth hormone excess. We described the case of a 38 year-old man who presented to the emergency room with a 6-week history of polydipsia, polyuria, polyphagia and weight loss. He also had nausea, vomiting and abdominal pain from two days before admission...
2018: Medicina
https://www.readbyqxmd.com/read/29656095/a-protocol-of-human-animal-interaction-to-habituate-young-sheep-and-goats-for-behavioural-studies
#17
P G González-Pech, C G Marín-Tun, D A Valladares-González, J Ventura-Cordero, G I Ortiz-Ocampo, R Cámara-Sarmiento, C Sandoval-Castro, J F J Torres-Acosta
Animal habituation is key to obtain reliable data on behavioural studies but detailed procedures to achieve it are scarce. This study designed a set of actions to habituate sheep and goats to human observers. Pelibuey sheep (n = 15) and Criollo goats (n = 10) were classified as (a) avoider, flight from human interaction, or (b) follower, seek human interaction. Habituation was measured by the reduction of flight distance by avoiders, or number of followers in the presence of observers. The habituation protocol consisted of a gradually increased series of five manoeuvres, either challenge (for avoiders) or evasion (for seekers), performed first inside a pen and subsequently in a grass paddock...
April 12, 2018: Behavioural Processes
https://www.readbyqxmd.com/read/29650461/towards-designing-a-synthetic-antituberculosis-vaccine-the-rv3587c-peptide-inhibits-mycobacterial-entry-to-host-cells
#18
Mary Lilian Carabali-Isajar, Marisol Ocampo, Deisy Carolina Rodriguez, Magnolia Vanegas, Hernando Curtidor, Manuel Alfonso Patarroyo, Manuel Elkin Patarroyo
Mycobacterium tuberculosis is considered one of the most successful pathogens in the history of mankind, having caused 1.7 million deaths in 2016. The amount of resistant and extensively resistant strains has increased; BCG has been the only vaccine to be produced in more than 100 years though it is still unable to prevent the disease's most disseminated form in adults; pulmonary tuberculosis. The search is thus still on-going for candidate antigens for an antituberculosis vaccine. This paper reports the use of a logical and rational methodology for finding such antigens, this time as peptides derived from the Rv3587c membrane protein...
April 4, 2018: Bioorganic & Medicinal Chemistry
https://www.readbyqxmd.com/read/29649858/pharmacokinetics-of-enrofloxacin-hcl-2h-2-o-enro-c-in-dogs-and-pk-pd-monte-carlo-simulations-against-leptospira-sp
#19
Hector Sumano, Luis Ocampo, Graciela Tapia, C de Jesus Mendoza, Lilia Gutierrez
Pharmacokinetics/pharmacodynamics (PK/PD) ratios of reference enrofloxacin (Enro-R) and enrofloxacin as HCl-2H2 O (Enro-C), as well as Monte Carlo simulations based on composite MIC50 and MIC90 vs. Leptospira sp., were carried out in dogs after their IM and oral administration (10 mg/kg). Plasma determination of enrofloxacin was achieved by means of high performance liquid chromatography (HPLC). Maximum plasma concentration values after oral administration were 1.47 ± 0.19 µg/mL and 5.3 ± 0.84 µg/mL for Enro-R and Enro-C, respectively, and 1...
April 12, 2018: Journal of Veterinary Science
https://www.readbyqxmd.com/read/29628310/gcn4-binding-in-coding-regions-can-activate-internal-and-canonical-5-promoters-in-yeast
#20
Yashpal Rawal, Răzvan V Chereji, Vishalini Valabhoju, Hongfang Qiu, Josefina Ocampo, David J Clark, Alan G Hinnebusch
Gcn4 is a yeast transcriptional activator induced by amino acid starvation. ChIP-seq analysis revealed 546 genomic sites occupied by Gcn4 in starved cells, representing ∼30% of Gcn4-binding motifs. Surprisingly, only ∼40% of the bound sites are in promoters, of which only ∼60% activate transcription, indicating extensive negative control over Gcn4 function. Most of the remaining ∼300 Gcn4-bound sites are within coding sequences (CDSs), with ∼75 representing the only bound sites near Gcn4-induced genes...
April 2, 2018: Molecular Cell
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