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Carlos García Encinas, Patricia Guzmán Rojas, Jorge Espinoza-Rios, Víctor Aguilar Sánchez, Eduar Bravo Paredes, Andrea Portocarrero, Jorge Huerta-Mercado, Jaime Cáceres Pizarro, Alejandro Bussalleu Rivera
Inflammatory bowel disease is associated with extraintestinal manifestations. Among these manifestations is the venous tromboembolism which presents a risk three times more than that presented in general population. We report the case of a 61-year-old male with a history of abdominal pain, chronic diarrhea and fever, with leukocytosis, and fecal samples containing leukocytes, partial ileal stenosis with multiple ulcers in the enteroscopy, with histologic findings compatible with Crohn's disease. The patient has a good outcome with prednisone and maintenence azathioprine, presenting at the fifth month deep venous thrombosis of both lower extremities that resolvewith anticoagulation treatment...
July 2016: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
Cemşit Karakurt, Rıza Türköz, Bülent Sarıtaş, Serkan Çelik, Özlem Elkıran
UNLABELLED: Cardiac pseudoaneurysm is an extremely rare condition in children. It can be congenital or acquired and has been primarily described in the left side of the heart. The congenital form of pseudoaneurysm is thought to be related to muscular dysplasia of the muscular layer of the heart. The acquired form is related to myocardial infarction, infective endocarditis or chest trauma. In this report we described a 5-month-old baby with left atrial pseudoaneurysm who was referred to our hospital due to tachycardia and hemodynamic instability...
January 2016: Acta Cardiol Sin
Cornelius Barlascini, Maria Grazia Piroddi, Alessandro Perazzo, Renata Senarega, Mario Santo, Antonello Nicolini
The ovarian hyperstimulation syndrome (OHSS) is a serious but rarely fatal complication of medical interventions that seek to induce fertility; it is typically encountered in women who undergo controlled ovarian hyperstimulation, but there are very rare patients who have genetic defects who present with OHSS. In recent years, its pathogenesis has been elucidated; this knowledge will decrease the frequency of this syndrome. Clinical signs may include any or all of the following: rapid weight gain, ascites, oliguria, hemoconcentration, leukocytosis, along with intravascular hypovolemia, hyponatremia, and hyperkalemia...
2015: Pneumologia: Revista Societății Române de Pneumologie
Fulvio Pomero, Matteo Nicola Dario Di Minno, Luigi Fenoglio, Monica Gianni, Walter Ageno, Francesco Dentali
Diabetes mellitus (DM), a chronic disease with an increasing incidence and prevalence worldwide, is an established risk factor for arterial cardiovascular, cerebrovascular and peripheral vascular diseases including acute myocardial infarction, stroke and peripheral artery disease. On the other hand, its role as independent risk factor for venous thromboembolism (VTE) and for cardioembolic stroke or systemic embolism (SE) in patients with atrial fibrillation (AF) is more conflicting. Venous and arterial thromboses have traditionally been regarded as separate diseases, but recent studies have documented an association between these vascular complications...
December 2015: Acta Diabetologica
Petros Zezos, Georgios Kouklakis, Fred Saibil
Patients with inflammatory bowel disease (IBD) have an increased risk of vascular complications. Thromboembolic complications, both venous and arterial, are serious extraintestinal manifestations complicating the course of IBD and can lead to significant morbidity and mortality. Patients with IBD are more prone to thromboembolic complications and IBD per se is a risk factor for thromboembolic disease. Data suggest that thrombosis is a specific feature of IBD that can be involved in both the occurrence of thromboembolic events and the pathogenesis of the disease...
October 14, 2014: World Journal of Gastroenterology: WJG
Jan Vojáček
Recently, new peroral antithrombotic agents have proved better prevention of thrombotic complications in many clinical events such as acute coronary syndrome, tromboembolic disease or atrial fibrillation. New peroral anticoagulants (NPA) were introduced - dabigatran, rivaroxaban and apixaban and new antiplatelet agents - ticagrelol and prasugrel. Outcomes of pilot studies: RE-LY, ROCKET AF, ARISTOTLE, PLATO a TIMI 38 TRITON and subsequent clinical experiences supported their usage. NPA have proved non-inferiority in incidence of stroke or systemic embolism...
April 2014: Vnitr̆ní Lékar̆ství
P Gavornik, A Dukát, L Gašpar
UNLABELLED: The aim of Guidelines of the Angiology Section of the Slovak Medical Chamber (AS SMC) is to address a last european guidelines for the management of thrombophlebitis superficialis, as well as results in evidence based  medicine (EBM) in order to assess their contribution to our expanding knowledge on rational management of thrombophlebitis superficialis. DISCUSSION: Superficial thrombophlebitis is a common disease, usually considered to be benign. However, the practice of systemic duplex ultrasonography has revealed a large number of cases of deep vein thrombosis concomitant with superficial thrombophlebitis...
November 2013: Vnitr̆ní Lékar̆ství
Vesna Cukic, Rusmir Baljic
INTRODUCTION: Pulmonary thromboembolism (PTE) is the most serious manifestation of thromboembolic disease. OBJECTIVE: To determine the most common risk and etiologic factors of pulmonary tromboembolism in patients treated in Intensive care unit of Clinic for Pulmonary Diseases and TB "Podhrastovi" in three-year- period from 2008. to 2010. MATERIAL AND METHODS: We retrospectively analysed patients with PTE treated in Intensive care unit of Clinic for Pulmonary Diseases and TB "Podhrastovi" in three-year period from 2008...
2012: Materia Socio-medica
V I Shevelev, S G Kanorsky
We compared the efficacy and safety of warfarin, dabigartan, and clopidogrel used to prevent tromboembolism in 210 elderly patients with non-valvular atrial fibrillation depending on the age. In patients aged 65--74 yr treatment with dabigartan (110 mg twice daily) for 6 months was associated with ischemic stroke as frequently as warfarin therapy but less frequently than with severe hemorrhages (4.4 vs. 27.7%, p < 0.05). Clopidogrel prevented stroke as effectively as warfarin and dabigartan and was equally safe...
2012: Klinicheskaia Meditsina
Wojciech Poncyljusz, Aleksander Falkowski, Monika Rać, Leszek Sagan, Ireneusz Kojder
Thrombotic occlusion of the middle cerebral artery's branch occurred just after embolization of a nonruptured cerebral aneurysm. Bail-out stent-assisted mechanical thrombectomy of the clot was performed. DSA revealed normal vessel patency at the end of the procedure. There were no adverse events related to this thrombectomy, and the patient recovered from the embolization with minor neurologic deficit. There was no neurologic deficit after 90 days follow-up.
2012: Przegla̧d Lekarski
Airi Jussila, Irina Rinta-Kiikka, Pekka Collin
Tromboembolic complications are 2-4-fold more likely in patients with inflammatory bowel disease (IBD) than in healthy individuals; active IBD may increase the relative risk even 15-fold. Deep vein thrombosis and pulmonary embolism are the most common involvements, but also atypical forms occur. We describe such uncommon thrombotic manifestations in two IBD patients: one had mesenterial vein and the other cavernoid sinus thrombosis. The risk of thrombotic complications should be estimated individually, and prophylactic management with low molecular weight heparin should be considered in hospitalized IBD patients...
2012: Duodecim; Lääketieteellinen Aikakauskirja
M Táborský, P Heinc, Y Hrčková
Dabigatrane is the first new generation antiacoagulant that at a dose of 150 mg twice daily was, in the RE-LY study, more effective in cerebrovascular event and systemic embolisation prevention than well-controlled warfarin and had comparable or better safety profile than well-controlled warfarin. The 110 mg twice daily dose showed comparable efficacy and superior safety against warfarin. Crucial and unique among modern anticoagulants is its ability to significantly reduce ischemic as well as hemorrhagic CVEs at a dose of 150 mg twice daily...
October 2012: Vnitr̆ní Lékar̆ství
Maarten J Postma, Bregt S Kappelhoff, Marinus van Hulst, Jacobus R B J Brouwers
OBJECTIVES: Dabigatran etexilate is a new oral direct thrombin inhibitor for prophylaxis of venous thromboembolism (VTE) in patients who have elective surgery for total hip replacement (THR) or total knee replacement (TKR). Among the advantages of dabigatran etexilate over subcutaneous prophylaxis with Low Molecular Weight Heparin (LMWH) are reduced resource uses for (i) teaching patients to self-inject; (ii) home-care visits for subcutaneous administration; and (iii) absence of heparin-induced thrombocytopenia (HIT)...
2012: Journal of Medical Economics
O I Novosad, I A Kriachok, T V Kadnikova, K S Filonenko, I B Tytorenko, A V Martynchyk, O M Aleksyk, Iu O Gusachenko, I A Filonenko
Achievements of world practice about development and prophilaxis of tromboembolic events (VTE) in cancer patients. Particular attention is paid to prevention of VTE in patients with multiply myeloma who receive chemotherapy with Thalidomide.
April 2011: Likars'ka Sprava
K Bremme, R Rafik Hamad, Elisabeth Berg, K Strandberg, J Stenflo
BACKGROUND: The risk of venous tromboembolism (VTE) in women taking combined oral contraceptives (COCs) is attributed to changes in coagulation and fibrinolysis. The impact of the COCs may be greater in women with preexisting thrombophilic defects. Nevertheless most women who suffer from venous thrombosis do not have any of the well known hereditary or acquired risk factors. A simple and sensitive marker of"thrombogenicity" has not been identified. OBJECTIVES: To investigate the effects of two different monophasic combined oral contraceptives (COCs) on the plasma concentrations of activated protein C-inhibitor of protein C ( APC-PCI) and on comparable hemostatic factors in fertile women...
October 2012: Thrombosis Research
Luciano Rapold Souza, Carlos Manuel de Almeida Brandão, Pablo Maria Alberto Pomerantzeff, Osanam Amorim Leite Filho, Luiz Francisco Cardoso, Noedir Antonio Groppo Stolf
INTRODUCTION: The good results of open mitral commissurotomy are well known and there is a hypothesis that it could provide better results in patients selected by echocardiographic score. OBJECTIVE: The purpose of this study is to analyze the late results with open mitral commissurotomy in patients selected by score and to identify variables influencing these results. METHODS: From January 1990 to August 1994, 50 patients were submitted to open mitral commissurotomy due to rheumatic mitral stenosis in Heart Institute of University of Sao Paulo Medical School...
July 2011: Revista Brasileira de Cirurgia Cardiovascular
A Silvani, P Gaviani, E Lamperti, A Botturi, D Ferrari, G Simonetti, L Fariselli, A Salmaggi
In malignant gliomas, the management of symptoms and minimization of side effects assume major importance. Corticosteroids provide transient relief from neurological symptoms. However, treatment with steroids is also commonly associated with considerable side-effects including: hyperglycemia, osteoporosis, myopathy, lymphopenia and others. Sometimes, antiepileptic drugs may contribute to clinical decline of neuro-oncological patients in stable disease not only by neuropsychological impairment but also by metabolic interations...
November 2011: Neurological Sciences
T A Zhirova, I L Shlykov, V A Rudnov
The aim of the study is to measure the effectiveness and safety of tranexam acid during hip and knee joint endoprothesis surgeries. Tranexam (Mir-Pharm, Russia) was administered to 45 patients 30 minutes before the surgery in the dose of 10-15 mg/kg and 6 hours after first infusion in the same dose. In the control group (n = 45) Tranexam was not administered. The intraoperative, drain and general blood loss, need of donor blood and dynamics of hematological parameters were assessed. The total number of complications and potential transfusion complications was measured...
May 2011: Anesteziologiia i Reanimatologiia
V Tsankova, V Petrov, A Astrug
There is consistent evidence that the use of oral contraceptives and is associated with increased risk of deep vein thrombosis. The study objective was to assess age specific incidence of deep venous thrombosis and pulmonary embolism in women 20 to 50 years of age associated with the use of oral contraceptives, and smoking habit. A case-control study of vein thrombosis was conducted in National Heart Hospital in Sofia. The study consists of studies for vascular events (peripheral vascular disease) during hormonal therapy...
2010: Akusherstvo i Ginekologii︠a︡
Ana Paula Torres Liberati, Camila Ferrari Ribeiro, Thelma Skare
Ischemia is common in systemic scleroderma and it is caused by vasospasm and thrombosis. In the present study we analyzed the association of peripheral vascular events and anticardiolipin (aCl) antibodies in 54 patients suffering from systemic scleroderma. The results showed that 100% of the patients presented Raynaud; 59.2% presented digital micro scars; 43.3%, presented teleangiectasies and 14.8%, presented peripheral thromboembolism. ACl IgG were positive in 9.2% and IgM, in 7.4%. Peripheral tromboembolic phenomena had a positive association with aCl IgG (p=0...
May 2010: Anais Brasileiros de Dermatologia
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