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REVIEW
Ahmad Parvinian, Scott M Thompson, John J Schmitz, Brian T Welch, Rebecca Hibbert, Daniel A Adamo, A Nicholas Kurup
PURPOSE OF REVIEW: To provide an update on the current state of percutaneous thermal ablation in the treatment of sarcoma. RECENT FINDINGS: Data continue to accrue in support of ablation for local control and palliation of specific sarcoma subtypes such as extra-abdominal desmoid fibromatosis and for broader indications such as the treatment of oligometastatic disease. The synergistic possibilities of various combination therapies such as cryoablation and immunotherapy represent intriguing areas of active investigation...
April 22, 2024: Current Oncology Reports
#2
JOURNAL ARTICLE
Dominika Adamczyk, Dominika Maison, Stella Lignou, Omobolanle O Oloyede, Miriam Clegg, Lisa Methven, Carol Fairfield, Margot Gosney, Maria José Hernando, Javier Amézaga, Mercedes Caro, Itziar Tueros
PURPOSE: Many cancer patients have problems eating which are usually connected to taste and smell alterations due to side effects of cancer treatment. These problems have consequences both in terms of malnutrition and reduced quality of life. In order to explore social and psychological consequences of eating problems in cancer patients, qualitative interviews were conducted with cancer patients, their caregivers and healthcare professionals. METHODS: The study was conducted in three European countries (Poland, Spain and the UK) that differed in culture, oncology care approaches and availability of nutritional products targeted to cancer patients in the market...
April 22, 2024: Supportive Care in Cancer
#3
JOURNAL ARTICLE
Gaurav Karna, Amit Sehrawat, Saurabh Karna, Ravi Kant, Deepak Sundriyal, Summi Karn, Dipesh Jha
BACKGROUND: Noncommunicable diseases (NCDs) contribute significantly to global morbidity and mortality, with cancer being one of the leading causes. In this prospective observational study, we aimed to investigate the prevalence and impact of endocrine disorders, specifically diabetes and thyroid dysfunction, in patients with advanced metastatic cancer undergoing cancer-directed therapy. METHODS: Over 15 months, we recruited 100 histologically proven advanced metastatic cancer patients from the Department of Medical Oncology Haematology, All India Institute of Medical Sciences, Rishikesh, and conducted institutional-based prospective observational study...
April 2024: Cancer reports
#4
JOURNAL ARTICLE
Nozomi Okamura, Emi Kubo, Ayaka Ishida, Sakiho Noda, Mariko Harada, Keisuke Ishizuka, Yujiro Inoue, Kazuhiro Kosugi, Tomofumi Miura
PURPOSE: To compare the details, oncologists include in discharge letters with what home care physicians need. Although discharge letters are important to share patients' information for home palliative care, few studies have compared the details, especially patients' emotions, regarding what oncologists include in discharge letters and home care physicians' needs. METHODS: This cross-sectional study was conducted by sending anonymous, self-administered questionnaires to 500 certified oncologists (OCs) and 500 directors of home care supporting clinics (HCs) in Japan between March and May 2023...
April 22, 2024: Supportive Care in Cancer
#5
JOURNAL ARTICLE
Brooke Worster, Yifan Zhu, Gregory Garber, Sawyer Kieffer, Aaron Smith-McLallen
BACKGROUND: Supportive oncology (SO) care reduces symptom severity, admissions, and costs in patients with advanced cancer. This study examines the impact of SO care on utilization and costs. METHODS: Retrospective analysis of utilization and costs comparing patients enrolled in SO versus three comparison cohorts who did not receive SO. Using claims, the authors estimated differences in health care utilization and cost between the treatment group and comparison cohorts...
April 20, 2024: Cancer
#6
JOURNAL ARTICLE
Natural history and health care burden of non-curative treatment for muscle-invasive bladder cancer.
Haim Herzberg, Yossi Ventura, Karin Lifshitz, Ziv Savin, Shay Golan, Jack Baniel, Ofer Yossepowitch, Roy Mano
OBJECTIVE: Muscle-invasive bladder cancer is an aggressive disease. Yet, many patients, especially those with advanced age and multiple comorbidities, do not receive treatment with curative intent. We evaluated the disease course and health care burden of these patients. MATERIALS AND METHODS: Bi-center, retrospective analysis of patients diagnosed with muscle-invasive bladder cancer who did not undergo curative-intent treatment (radical cystectomy or trimodal therapy) between 2016 and 2021...
April 18, 2024: Urologic Oncology
#7
JOURNAL ARTICLE
Sarah Ehmann, Clarissa Lam, Qin Zhou, Alexia Iasonos, Rachel N Grisham, William P Tew, Roisin E O'Cearbhaill, Kara Long Roche, Oliver Zivanovic, Yukio Sonoda, Dennis S Chi, Ginger J Gardner
OBJECTIVES: To compare oncologic outcomes of secondary cytoreductive surgery (SCS) before and after FDA approval of Poly(ADP-ribose) polymerase inhibitor (PARPi) and bevacizumab maintenance therapies for platinum-sensitive recurrent ovarian cancer (PS-ROC). METHODS: Patients who underwent SCS for first recurrence of PS-ROC from 1/1/2013-1/1/2020 were identified. Exclusion criteria included prior chemotherapy for recurrence, bowel obstruction procedures, and palliative surgery...
April 18, 2024: Gynecologic Oncology
#8
REVIEW
Javier Fernández-Sánchez, Daniel Trujillo-Colmena, Adrián Rodríguez-Castaño, Ana Myriam Lavín-Pérez, Juan Del Coso, Arturo Casado, Daniel Collado-Mateo
PURPOSE: A cancer diagnosis is commonly associated with a decline in patient's life satisfaction and more pessimistic expectations about the future. The identification of strategies to improve life satisfaction in patients with cancer is of great interest to health practitioners since it may be associated with a better prognosis of cancer and higher survival rates. Previous meta-analyses and reviews concluded that exercise could significantly improve health-related quality of life in this population, but the effects of exercise on life satisfaction are still not well-known...
April 19, 2024: Supportive Care in Cancer
#9
JOURNAL ARTICLE
Paolo Morgagni, Maria Bencivenga, Fatima Carneiro, Stefano Cascinu, Sarah Derks, Maria Di Bartolomeo, Claire Donohoe, Clarisse Eveno, Suzanne Gisbertz, Peter Grimminger, Ines Gockel, Heike Grabsh, Paulo Kassab, Rupert Langer, Sara Lonardi, Marco Maltoni, Sheraz Markar, Markus Moehler, Daniele Marrelli, Maria Antonietta Mazzei, Davide Melisi, Carlo Milandri, Paul Stefan Moenig, Bianca Mostert, Gianni Mura, Wojciech Polkowski, John Reynolds, Luca Saragoni, Mark I Van Berge Henegouwen, Richard Van Hillegersberg, Michael Vieth, Giuseppe Verlato, Lorena Torroni, Bas Wijnhoven, Guido Alberto Massimo Tiberio, Han-Kwang Yang, Franco Roviello, Giovanni de Manzoni
BACKGROUND: Many gastric cancer patients in Western countries are diagnosed as metastatic with a median overall survival of less than twelve months using standard chemotherapy. Innovative treatments, like targeted therapy or immunotherapy, have recently proved to ameliorate prognosis, but a general agreement on managing oligometastatic disease has yet to be achieved. An international multi-disciplinary workshop was held in Bertinoro, Italy, in November 2022 to verify whether achieving a consensus on at least some topics was possible...
April 18, 2024: Gastric Cancer
#10
JOURNAL ARTICLE
Betty Ferrell, Justin Sanders
Patients with cancer and their families comprise a significant population served by palliative care. Close collaboration between oncology clinicians and palliative care teams has demonstrated improved patient-centered care, especially when this care is integrated early in the course of the disease. The American Society of Clinical Oncology recently released their updated clinical practice guidelines for palliative care in oncology, which provide new opportunities for collaboration to expand the scope of care...
April 18, 2024: Journal of Palliative Medicine
#11
JOURNAL ARTICLE
Mahesh Menon, Subhashini Perumal, Raza Ahmad, Priya Das, Shiv Pratap Singh Rana, Asif Sardar
OBJECTIVES: Our research aimed to examine the characteristics of palliative oncology patients hospitalised through an emergency to look for the symptom profile, characteristics of dyselectrolytemia and blood investigations, and possible associations with mortality. MATERIALS AND METHODS: After institutional review board approval, a retrospective, observational study of patients hospitalised in our tertiary care specialty oncology hospital was undertaken. Records of hospitalised cancer patients admitted from the emergency department under palliative care from January 2019 to October 2021 were examined...
2024: Indian Journal of Palliative Care
#12
REVIEW
Samiyah Alsaiari, Aisha Alhofaian, Afnan Tunsi
Nursing care plays a crucial role in the management of cancer pain, but nurses often face challenges due to inadequate knowledge, negative attitudes towards opioid use, and suboptimal pain evaluation practices. This scoping review aims to examine nurses' level of knowledge and practices in cancer pain management and identify the barriers they encounter when caring for patients with cancer. A comprehensive search of 50 articles was conducted using multiple databases such as Web of Science, PubMed, Ovid MEDLINE, Embase Classic + EMBASE (Ovid), The Cochrane Library (Wiley), and CINAHL...
2024: Indian Journal of Palliative Care
#13
JOURNAL ARTICLE
Udit Nindra, Peter Lin, Therese Becker, Tara L Roberts, Wei Chua
Prostate cancer remains one of the leading causes of cancer-related death in the world. There have been significant advances in chemotherapy, hormonal therapy and targeted therapy options for patients with castrate-resistant disease. However, these systemic treatments are often associated with unwanted toxicities. Targeted therapy with radiopharmaceuticals has become of key interest to limit systemic toxicity and provides a more precision oncology approach to treatment. Strontium-89, Samarium-153 EDTMP and Radium-223 have been trialled with mixed results...
April 17, 2024: Journal of Medical Imaging and Radiation Oncology
#14
JOURNAL ARTICLE
M Field, S Vinod, G P Delaney, N Aherne, M Bailey, M Carolan, A Dekker, S Greenham, E Hau, J Lehmann, J Ludbrook, A Miller, A Rezo, J Selvaraj, J Sykes, D Thwaites, L Holloway
AIMS: The objective of this study was to develop a two-year overall survival model for inoperable stage I-III non-small cell lung cancer (NSCLC) patients using routine radiation oncology data over a federated (distributed) learning network and evaluate the potential of decision support for curative versus palliative radiotherapy. METHODS: A federated infrastructure of data extraction, de-identification, standardisation, image analysis, and modelling was installed for seven clinics to obtain clinical and imaging features and survival information for patients treated in 2011-2019...
March 16, 2024: Clinical Oncology: a Journal of the Royal College of Radiologists
#15
JOURNAL ARTICLE
C Sanghera, D P McClurg, C M Jones
BACKGROUND AND AIM: There has been limited progress made in improving the suboptimal outcomes delivered by conventionally fractionated radiotherapy (RT) for oesophageal adenocarcinoma (OAC) and squamous cell carcinoma (OSCC). A greater biological effect may be achieved using hypofractionated RT (HFRT), though the toxicity, tolerability and efficacy of this approach in OAC and OSCC is uncertain. METHODS: A systematic literature review was carried out in accordance with Preferred Reporting Items for Systematic Reviews guidance...
March 18, 2024: Clinical Oncology: a Journal of the Royal College of Radiologists
#16
JOURNAL ARTICLE
Katrine Storm Piper, Charlotte Suetta, Jakob Vasehus Schou, Jesper Ryg, Hanne Elkjær Andersen, Line Vind Langevad, Delaney Evering, Marta Kramer Mikkelsen, Cecilia Lund, Jan Christensen
INTRODUCTION: Older patients with cancer range from fit to frail with various comorbidities and resilience to chemotherapy. Besides nausea and fatigue, a significant number of patients experience dizziness and impaired walking balance after chemotherapy, which can have great impact on their functional ability and health related quality of life. Symptoms are easily overlooked and therefore often underreported and managed, which is why symptoms could end up as long-lasting side effects...
April 16, 2024: Journal of Geriatric Oncology
#17
JOURNAL ARTICLE
Jay Desai, Sujay Rajkumar, Matthew J Shepard, John Herbst, Stephen M Karlovits, Shakir Hasan, Zachary D Horne, Rodney E Wegner
PURPOSE: Diffuse midline gliomas (DMG) include all midline gliomas with a point mutation to the histone H3 gene resulting in the substitution of a lysine with a methionine (K27M). These tumors are classified as World Health Organization grade 4 with a mean survival between 9- and 19-months following diagnosis. There is currently no standard of care for DMG, and palliative radiation therapy has been proven to only extend survival by months. Our current study aims to report current treatment trends and predictors of the overall survival of DMG...
April 17, 2024: Journal of Neuro-oncology
#18
JOURNAL ARTICLE
Akansha Choudhary, Linu A Jacob, Suresh Babu, Lokesh K N, Rudresha A H, Rajeev L K, Smitha Saldanha, Tarjina Begum
Considerable advances in the diagnosis and treatment of cancer have made a huge impact on morbidity and mortality from neoplastic diseases. However, cancer remains the leading cause of death across the world. This is a retrospective study carried out at a tertiary cancer care centre (Kidwai Memorial Institute of Oncology, Bangalore) in South India. Case records of all cancer patients who died while receiving inpatient treatment between January 2022 and December 2022 under the Department of Medical Oncology were reviewed and studied...
March 2024: Curēus
#19
JOURNAL ARTICLE
Ping Chen, Mingfu Ding, Changlin Li, Yujuan Long, Deng Pan, Li Ma, Taiguo Liu, Cheng Yi
BACKGROUND: Advanced cancer patients with good Eastern Cooperative Oncology Group (ECOG) performance status (score 0-1) are underrepresented in current qualitative reports compared with their dying counterparts. AIM: To explore the experiences and care needs of advanced cancer patients with good ECOG. DESIGN: A qualitative phenomenological approach using semi-structured interview was employed. Data was analyzed using the Colaizzi's method...
April 17, 2024: BMC Palliative Care
#20
JOURNAL ARTICLE
Carolin Siech, Andrea Baudo, Mario de Angelis, Letizia Maria Ippolita Jannello, Francesco Di Bello, Jordan A Goyal, Zhe Tian, Fred Saad, Shahrokh F Shariat, Nicola Longo, Luca Carmignani, Ottavio de Cobelli, Alberto Briganti, Séverine Banek, Philipp Mandel, Luis A Kluth, Felix K H Chun, Pierre I Karakiewicz
BACKGROUND: In metastatic urethral cancer, temporal trends, and patterns of inpatient palliative care (IPC) use are unknown. METHODS: Relying on the National Inpatient Sample (2006-2019), metastatic urethral cancer patients were stratified according to IPC use. Estimated annual percentage changes (EAPC) analyses and multivariable logistic regression models (LRM) for the prediction of IPC use were fitted. RESULTS: Of 1,106 metastatic urethral cancer patients, 199 (18%) received IPC...
April 15, 2024: Urologic Oncology
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