keyword
MENU ▼
Read by QxMD icon Read
search

stimuli responsive

keyword
https://www.readbyqxmd.com/read/28738665/aggregation-control-by-multi-stimuli-responsive-poly-n-vinylamide-derivatives-in-aqueous-system
#1
Ryo Kawatani, Yasuhiro Nishiyama, Hironari Kamikubo, Kiyomi Kakiuchi, Hiroharu Ajiro
Thermal and photo responsive copolymer based on N-vinylamide backbone was designed. Methoxyethyl group and azobenzene were selected to improve hydrophilicity and photoresponsive moieties, respectively. The N-(methoxyethyl)-N-vinylformamide was synthesized and copolymerized with N-vinylformamide by free radical polymerization. In order to control the nanosized structures, poly(N-vinylformamide) derivatives bearing azobenzene at the N-position near to the vinyl polymer main chain were synthesized by polymer reaction with the poly(N-vinylformamide-co-N-(methoxyethyl)-N-vinylformamide) and azobenzene...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28738063/atypical-speech-versus-non-speech-detection-and-discrimination-in-4-to-6-yr-old-children-with-autism-spectrum-disorder-an-erp-study
#2
Alena Galilee, Chrysi Stefanidou, Joseph P McCleery
Previous event-related potential (ERP) research utilizing oddball stimulus paradigms suggests diminished processing of speech versus non-speech sounds in children with an Autism Spectrum Disorder (ASD). However, brain mechanisms underlying these speech processing abnormalities, and to what extent they are related to poor language abilities in this population remain unknown. In the current study, we utilized a novel paired repetition paradigm in order to investigate ERP responses associated with the detection and discrimination of speech and non-speech sounds in 4- to 6-year old children with ASD, compared with gender and verbal age matched controls...
2017: PloS One
https://www.readbyqxmd.com/read/28737801/optical-properties-and-mechanofluorochromism-of-new-bodipy-dyes-based-on-the-pyridine-pyrimidine-hybrid-structure
#3
Yi Liu, Jicheng Duan, Fen Qi, Dan Tian, Xiaoqing Wang, Zhipeng Liu, Wei Huang
A new family of BODIPY dyes (PPB1-4) based on the pyridine-pyrimidine hybrid structure has been synthesized. These dyes show high cyan fluorescence in hexane with quantum yields (Φf) ranging from 0.33 to 0.90. Interestingly, moderate fluorescence of PPB1-4 is observed in the solid state (Φf, 0.11-0.26). X-ray structure analysis demonstrates that H-aggregation should be responsible for the red-shifted and quenched emission in the solid state. Moreover, PPB1-4 show high contrast and reversible mechanochromic fluorescence based on the proposed mechanism of mechanical stimuli triggered dimer dissolution and formation...
July 24, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28737765/adrenocorticotropic-hormone-and-1-25-dihydroxyvitamin-d3-enhance-human-osteogenesis-in-vitro-by-synergistically-accelerating-the-expression-of-bone-specific-genes
#4
Irina L Tourkova, Li Liu, Nareerat Sutjarit, Quitterie C Larrouture, Jianhua Luo, Lisa J Robinson, Harry C Blair
To improve definition of the physical and hormonal support of bone formation, we studied differentiation of human osteoblasts in vitro at varying combinations of ACTH, 1α,25-dihydroxyvitamin D3 (1,25(OH)2D), and extracellular calcium, with and without added cortisol. Bone mineralization, alkaline phosphatase activity, and osteoblast-specific markers RunX2, osterix, and collagen I increased with 10 pM ACTH, 10 nM 1,25(OH)2D, or at 2 mM calcium with important synergistic activity of combinations of any of these stimuli...
July 24, 2017: Laboratory Investigation; a Journal of Technical Methods and Pathology
https://www.readbyqxmd.com/read/28737694/the-role-of-p16-ink4a-pathway-in-human-epidermal-stem-cell-self-renewal-aging-and-cancer
#5
REVIEW
Daniela D'Arcangelo, Lavinia Tinaburri, Elena Dellambra
The epidermis is a self-renewing tissue. The balance between proliferation and differentiation processes is tightly regulated to ensure the maintenance of the stem cell (SC) population in the epidermis during life. Aging and cancer may be considered related endpoints of accumulating damages within epidermal self-renewing compartment. p16(INK4a) is a potent inhibitor of the G1/S-phase transition of the cell cycle. p16(INK4a) governs the processes of SC self-renewal in several tissues and its deregulation may result in aging or tumor development...
July 22, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28737296/neurodevelopmental-maturation-as-a-function-of-irritable-temperament-insights-from-a-naturalistic-emotional-video-viewing-paradigm
#6
Helmet T Karim, Susan B Perlman
Few studies have investigated the neural systems involved in decreasing behavioral reactivity to emotional stimuli as children age. It has been suggested that this process may interact with temperament-linked variations in neurodevelopment to better explain individual differences in the maturation of emotion regulation. In this investigation, children ages 4 to 12 (n = 30, mean age = 7.62 years, SD = 1.71 years) and adults (n = 21, mean age = 26.67 years) watched clips from popular children's films containing positive, negative, or neutral emotional content during functional magnetic resonance imaging...
July 24, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28736924/evaluation-of-spiral-acquisition-variants-for-functional-imaging-of-human-superior-colliculus-at-3t-field-strength
#7
Vimal Singh, Josef Pfeuffer, Tiejun Zhao, David Ress
PURPOSE: High-resolution functional magnetic resonance imaging of human subcortical brain structures is challenging because of their deep location in the cranium, and their comparatively weak blood oxygen level dependent responses to strong stimuli. Magnetic resonance imaging data for subcortical brain regions exhibit both low signal-to-noise ratio and low functional contrast-to-noise ratio. To overcome these challenges, this work evaluates the use of dual-echo spiral variants that combine outward and inward trajectories...
July 24, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28736653/hemispheric-differences-in-electrical-and-hemodynamic-responses-during-hemifield-visual-stimulation-with-graded-contrasts
#8
Juanning Si, Xin Zhang, Yujin Zhang, Tianzi Jiang
A multimodal neuroimaging technique based on electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS) was used with horizontal hemifield visual stimuli with graded contrasts to investigate the retinotopic mapping more fully as well as to explore hemispheric differences in neuronal activity, the hemodynamic response, and the neurovascular coupling relationship in the visual cortex. The fNIRS results showed the expected activation over the contralateral hemisphere for both the left and right hemifield visual stimulations...
April 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28736529/detection-of-ros-induced-proteomic-signatures-by-mass-spectrometry
#9
REVIEW
Brian McDonagh
Reversible and irreversible post-translational modifications (PTMs) induced by endogenously generated reactive oxygen species (ROS) in regulatory enzymes and proteins plays an essential role in cellular signaling. Almost all cellular processes including metabolism, transcription, translation and degradation have been identified as containing redox regulated proteins. Specific redox modifications of key amino acids generated by ROS offers a dynamic and versatile means to rapidly alter the activity or functional structure of proteins in response to biochemical, environmental, genetic and pathological perturbations...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28736519/isolating-discriminant-neural-activity-in-the-presence-of-eye-movements-and-concurrent-task-demands
#10
Jon Touryan, Vernon J Lawhern, Patrick M Connolly, Nima Bigdely-Shamlo, Anthony J Ries
A growing number of studies use the combination of eye-tracking and electroencephalographic (EEG) measures to explore the neural processes that underlie visual perception. In these studies, fixation-related potentials (FRPs) are commonly used to quantify early and late stages of visual processing that follow the onset of each fixation. However, FRPs reflect a mixture of bottom-up (sensory-driven) and top-down (goal-directed) processes, in addition to eye movement artifacts and unrelated neural activity. At present there is little consensus on how to separate this evoked response into its constituent elements...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28736261/genetic-disruption-of-the-cardiomyocyte-circadian-clock-differentially-influences-insulin-mediated-processes-in-the-heart
#11
Graham R McGinnis, Yawen Tang, Rachel A Brewer, Manoja K Brahma, Haley L Stanley, Gobinath Shanmugam, Namakkal Soorappan Rajasekaran, Glenn C Rowe, Stuart J Frank, Adam R Wende, E Dale Abel, Heinrich Taegtmeyer, Silvio Litovsky, Victor Darley-Usmar, Jianhua Zhang, John C Chatham, Martin E Young
Cardiovascular physiology exhibits time-of-day-dependent oscillations, which are mediated by both extrinsic (e.g., environment/behavior) and intrinsic (e.g., circadian clock) factors. Disruption of circadian rhythms negatively affects multiple cardiometabolic parameters. Recent studies suggest that the cardiomyocyte circadian clock directly modulates responsiveness of the heart to metabolic stimuli (e.g., fatty acids) and stresses (e.g., ischemia/reperfusion). The aim of this study was to determine whether genetic disruption of the cardiomyocyte circadian clock impacts insulin-regulated pathways in the heart...
July 20, 2017: Journal of Molecular and Cellular Cardiology
https://www.readbyqxmd.com/read/28736172/early-integration-of-temperature-and-humidity-stimuli-in-the-drosophila-brain
#12
Dominic D Frank, Anders Enjin, Genevieve C Jouandet, Emanuela E Zaharieva, Alessia Para, Marcus C Stensmyr, Marco Gallio
The Drosophila antenna contains receptor neurons for mechanical, olfactory, thermal, and humidity stimuli. Neurons expressing the ionotropic receptor IR40a have been implicated in the selection of an appropriate humidity range [1, 2], but although previous work indicates that insect hygroreceptors may be made up by a "triad" of neurons (with a dry-, a cold-, and a humid-air-responding cell [3]), IR40a expression included only cold- and dry-air cells. Here, we report the identification of the humid-responding neuron that completes the hygrosensory triad in the Drosophila antenna...
July 13, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28736160/macrophage-phenotype-in-response-to-ecm-bioscaffolds
#13
REVIEW
Luai Huleihel, Jenna L Dziki, Joseph G Bartolacci, Theresa Rausch, Michelle E Scarritt, Madeline C Cramer, Tatiana Vorobyov, Samuel T LoPresti, Ilea T Swineheart, Lisa J White, Bryan N Brown, Stephen F Badylak
Macrophage presence and phenotype are critical determinants of the healing response following injury. Downregulation of the pro-inflammatory macrophage phenotype has been associated with the therapeutic use of bioscaffolds composed of extracellular matrix (ECM), but phenotypic characterization of macrophages has typically been limited to small number of non-specific cell surface markers or expressed proteins. The present study determined the response of both primary murine bone marrow derived macrophages (BMDM) and a transformed human mononuclear cell line (THP-1 cells) to degradation products of two different, commonly used ECM bioscaffolds; urinary bladder matrix (UBM-ECM) and small intestinal submucosa (SIS-ECM)...
July 20, 2017: Seminars in Immunology
https://www.readbyqxmd.com/read/28736107/cholinergic-opioid-interaction-in-anterior-cingulate-cortex-reduces-the-nociceptive-response-of-vocalization-in-guinea-pigs
#14
João Zugaib, Leda Menescal-de-Oliveira
The anterior cingulate cortex (ACC) is crucial in the modulation of the sensory, affective and cognitive aspects of nociceptive processing. Also, it participates in the plannig and execution of behavioral responses evoked by nociceptive stimuli via descending projections to the brainstem. In laboratory animals nociceptive experimental tests evaluate behavioral responses that preferentially express the sensory-discriminative or affective-motivational component of pain. The objective of this study was to investigate the participation of opioid and cholinergic neurotransmission in the ACC on different nociceptive responses in guinea pigs...
July 20, 2017: Brain Research
https://www.readbyqxmd.com/read/28735970/blunted-neural-response-to-implicit-negative-facial-affect-in-anorexia-nervosa
#15
Jenni Leppanen, Valentina Cardi, Yannis Paloyelis, Andy Simmons, Kate Tchanturia, Janet Treasure
BACKGROUND: People with anorexia nervosa (AN) have difficulties in a wide range of social-emotional processes. Previous work suggests atypical involvement of the prefrontal cortex (PFC), amygdala, insula, and fusiform gyri during social-emotional processing in AN. METHODS: Twenty women with AN and twenty healthy comparison (HC) women were presented with happy, fearful, and neutral faces during a functional magnetic resonance imaging study. Group differences were investigated in the following regions of interest: lateral PFC, amygdala, insula, and fusiform gyri...
July 20, 2017: Biological Psychology
https://www.readbyqxmd.com/read/28735528/lipids-evergreen-autofluorescent-biomarkers-for-the-liver-functional-profiling
#16
Anna Cleta Croce, Giovanni Bottiroli
Depending on their chemical nature, lipids can be classified in two main categories: hydrophilic, greatly contributing to membrane composition and subcellular organelle compartmentalization, and hydrophobic, mostly triglycerides, greatly enrolled in the storage and production of energy. In both cases, some lipid molecules can be involved as signaling agents in the regulation of metabolism and protective or damaging pathways in responses to harmful stimuli. These events could affect in particular the liver, because of its central role in the maintenance of lipid homeostasis...
June 1, 2017: European Journal of Histochemistry: EJH
https://www.readbyqxmd.com/read/28735410/rhizosphere-sampling-protocols-for-microbiome-16s-18s-its-rrna-library-preparation-and-enrichment-for-the-isolation-of-drought-tolerance-promoting-microbes
#17
Venkatachalam Lakshmanan, Prasun Ray, Kelly D Craven
Natural plant microbiomes are abundant and have a remarkably robust composition, both as epiphytes on the plant surface and as endophytes within plant tissues. Microbes in the former "habitat" face limited nutrients and harsh environmental conditions, while those in the latter likely lead a more sheltered existence. The most populous and diverse of these microbiomes are associated with the zone around the plant roots, commonly referred to as the rhizosphere. A majority of recent studies characterize these plant-associated microbiomes by community profiling of bacteria and fungi, using amplicon-based marker genes and next-generation sequencing (NGS)...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28735374/changes-in-global-transcriptional-profiling-of-women-following-obesity-surgery-bypass
#18
Marcela Augusta de Souza Pinhel, Natalia Yumi Noronha, Carolina Ferreira Nicoletti, Bruno Affonso Parente de Oliveira, Cristiana Cortes-Oliveira, Vitor Caressato Pinhanelli, Wilson Salgado Junior, Ana Julia Machry, Wilson Araújo da Silva Junior, Dorotéia Rossi Silva Souza, Júlio Sérgio Marchini, Carla Barbosa Nonino
BACKGROUND: Differential gene expression in peripheral blood mononuclear cells (PBMCs) after Roux-en-Y gastric bypass (RYGB) is poorly characterized. Markers of these processes may provide a deeper understanding of the mechanisms that underlie these events. The main goal of this study was to identify changes in PBMC gene expression in women with obesity before and 6 months after RYGB-induced weight loss. METHODS: The ribonucleic acid (RNA) of PBMCs from 13 obese women was analyzed before and 6 months after RYGB; the RNA of PBMCs from nine healthy women served as control...
July 22, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28734865/single-factors-alone-can-induce-mesenchymal-like-morphology-but-not-promote-full-emt-in-breast-cancer-cell-lines-with-different-hormone-statuses
#19
Maria K Tveitarås, Inga Reigstad, Lina Leiss, Rolf K Reed, Linda Stuhr
BACKGROUND: Epithelial to mesenchymal transition (EMT) is considered to be important for cancer invasion and metastasis. Tumour hypoxia, in addition to Transforming Growth Factor-β (TGF-β) and Notch, amongst others, have been suggested to be involved in EMT. We therefore investigated if hypoxia, TGF-β1 and the Notch ligand Jagged-1 alone induced morphological changes with corresponding EMT signatures in different epithelial breast cancer cell lines in vitro. Furthermore, we also studied whether or not TGF-β1, or Jagged-1 in combination with hypoxia added any effect on EMT...
July 19, 2017: Experimental Cell Research
https://www.readbyqxmd.com/read/28734758/atypical-interference-control-in-children-with-ad-hd-with-elevated-theta-beta-ratio
#20
Da-Wei Zhang, Steven Roodenrys, Hui Li, Robert J Barry, Adam R Clarke, Zhanliang Wu, Qihua Zhao, Yan Song, Lu Liu, Qiujin Qian, Yufeng Wang, Stuart J Johnstone, Li Sun
The theta/beta ratio (TBR) is a major area of interest within electroencephalogram (EEG) research in AD/HD. While researchers suggest a prognostic role for TBR in AD/HD, its relationship to behavior remains uncertain. Recent evidence suggests that elevated TBR in AD/HD may be related to atypical inhibition, particularly at an attentional level. This study aimed to examine the performance on three inhibitory tasks of children with AD/HD. Fifty-eight children with AD/HD participated, divided into an elevated TBR (ET) group and a control group (CT)...
July 19, 2017: Biological Psychology
keyword
keyword
41483
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"