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Momodou G Bah, Zachary M Wilseck, Leanne Y Lin, Andrew J Peterson, Neeraj Chaudhary, Joseph J Gemmete
BACKGROUND: This case report highlights the rare association among a dental procedure, infective endocarditis, and an acute ischemic stroke. CASE DESCRIPTION: A 54-year-old woman who experienced an acute ischemic stroke 5 weeks after a tooth extraction is described. The initial symptoms of this patient included mild to moderate word-finding difficulty and right facial droop. Computed tomographic angiography revealed a left M1 segment middle cerebral artery occlusion (thrombolysis in cerebral infarction scale, 0) with reconstitution of the distal middle cerebral branches through arterial collaterals...
March 2024: Journal of the American Dental Association
#22
JOURNAL ARTICLE
Isabelle L Piotrowski, Hannah K Junge, Colin C Schwarzwald
Mitral and aortic valve insufficiencies have been commonly reported in horses. The objective of this study was to establish the use of acoustic cardiography (Audicor® ) in horses with aortic (AI) or mitral valve insufficiency (MI). A total of 17 healthy horses, 18 horses with AI, and 28 horses with MI were prospectively included. None of the horses was in heart failure. Echocardiography and Audicor® analyses were conducted. Electromechanical activating time (EMAT), rate-corrected EMATc, left ventricular systolic time (LVST), rate-corrected LVSTc, and intensity and persistence of the third and fourth heart sound (S3, S4) were reported by Audicor® ...
January 21, 2024: Animals: An Open Access Journal From MDPI
#23
JOURNAL ARTICLE
Alon Shechter, Mirae Lee, Danon Kaewkes, Vivek Patel, Ofir Koren, Tarun Chakravarty, Keita Koseki, Takashi Nagasaka, Sabah Skaf, Moody Makar, Raj R Makkar, Robert J Siegel
BACKGROUND: Limited data exist regarding the impact of mitral annular calcification (MAC) on outcomes of transcatheter edge-to-edge repair for mitral regurgitation (MR). METHODS: We retrospectively analyzed 968 individuals (median age, 79 [interquartile range, 70-86] years; 60.0% males; 51.8% with functional MR) who underwent an isolated, first-time intervention. Stratified by MAC extent per baseline transthoracic echocardiogram, the cohort was assessed for residual MR, functional status, all-cause mortality, heart failure hospitalizations, and mitral reinterventions post-procedure...
January 18, 2024: Circulation. Cardiovascular Interventions
#24
JOURNAL ARTICLE
André Luiz Cerqueira Almeida, Marcelo Dantas Tavares de Melo, David Costa de Souza Le Bihan, Marcelo Luiz Campos Vieira, José Luiz Barros Pena, José Maria Del Castillo, Henry Abensur, Renato de Aguiar Hortegal, Maria Estefania Bosco Otto, Rafael Bonafim Piveta, Maria Rosa Dantas, Jorge Eduardo Assef, Adenalva Lima de Souza Beck, Thais Harada Campos Espirito Santo, Tonnison de Oliveira Silva, Vera Maria Cury Salemi, Camila Rocon, Márcio Silva Miguel Lima, Silvio Henrique Barberato, Ana Clara Rodrigues, Arnaldo Rabschkowisky, Daniela do Carmo Rassi Frota, Eliza de Almeida Gripp, Rodrigo Bellio de Mattos Barretto, Sandra Marques E Silva, Sanderson Antonio Cauduro, Aurélio Carvalho Pinheiro, Salustiano Pereira de Araujo, Cintia Galhardo Tressino, Carlos Eduardo Suaide Silva, Claudia Gianini Monaco, Marcelo Goulart Paiva, Cláudio Henrique Fisher, Marco Stephan Lofrano Alves, Cláudia R Pinheiro de Castro Grau, Maria Veronica Camara Dos Santos, Isabel Cristina Britto Guimarães, Samira Saady Morhy, Gabriela Nunes Leal, Andressa Mussi Soares, Cecilia Beatriz Bittencourt Viana Cruz, Fabio Villaça Guimarães Filho, Bruna Morhy Borges Leal Assunção, Rafael Modesto Fernandes, Roberto Magalhães Saraiva, Jeane Mike Tsutsui, Fábio Luis de Jesus Soares, Sandra Nívea Dos Reis Saraiva Falcão, Viviane Tiemi Hotta, Anderson da Costa Armstrong, Daniel de Andrade Hygidio, Marcelo Haertel Miglioranza, Ana Cristina Camarozano, Marly Maria Uellendahl Lopes, Rodrigo Julio Cerci, Maria Eduarda Menezes de Siqueira, Jorge Andion Torreão, Carlos Eduardo Rochitte, Alex Felix
Central Illustration : Position Statement on the Use of Myocardial Strain in Cardiology Routines by the Brazilian Society of Cardiology's Department Of Cardiovascular Imaging - 2023 Proposal for including strain in the integrated diastolic function assessment algorithm, adapted from Nagueh et al.67 Am: mitral A-wave duration; Ap: reverse pulmonary A-wave duration; DD: diastolic dysfunction; LA: left atrium; LASr: LA strain reserve; LVGLS: left ventricular global longitudinal strain; TI: tricuspid insufficiency...
December 2023: Arquivos Brasileiros de Cardiologia
#25
Marah Mansour, Ahmed AlZoubi, Sham Zoukar, Ghina Aljammal, Raghad Makki, Noor Al Huda Khaled, Yara Aletesh, Rama Aljundi, Ahmad Mohammad Deeb, Mohammad Obada Ajlouni
INTRODUCTION AND IMPORTANCE: Edward syndrome is a severe chromosomal defect that occurs as a result of non-disjunction through meiosis. It presents with cardiac septal defects, horseshoe kidneys, patent ductus arteriosus, central nervous system dysgenesis, distinctive craniofacial deformities, and overriding or overlapping fingers. Klinefelter syndrome (47, XXY) is found in 1 in 660 newborn males. It is considered to be one of the most common genetic causes of infertility. It manifests with small firm testes, androgen insufficiency, and azoospermia...
January 2024: Annals of Medicine and Surgery
#26
REVIEW
Akshay Gaur, Fiona Carr, David Warriner
It is estimated that by 2050, 17% of the world's population will be greater than 85 years old, which, combined with cardiovascular disease (CVD) being the leading cause of death and disability, sets an unprecedented burden on our health and care systems. This perfect storm will be accompanied by a rise in the prevalence of CVD due to increased survival of patients with pre-existing CVD and the incidence of CVD that is associated with the process of ageing. In this review, we will focus on the diagnosis and management of common CVD conditions in old age, namely: heart failure (HF), coronary artery disease (CAD), atrial fibrillation (AF) and valvular heart disease (VHD)...
January 11, 2024: Heart
#27
Ana Correia de Sá, Marta Batista, Ana L Ferreira, Daniela Casanova, Bebiana Faria, Jorge Cotter
Systemic lupus erythematosus (SLE) is a disease characterized by clinical heterogeneity with unpredictable course. Several disease endotypes have been identified, including SLE with antiphospholipid syndrome (APS). We report a case of a pregnant woman with hypertension and proteinuria, diagnosed with APS, Libman-Sacks endocarditis that led to moderate to severe mitral valve insufficiency, and SLE. We describe the diagnostic steps, evolution, and complications. This case highlights the asynchrony behavior of SLE, emphasizing the importance of a multidisciplinary approach to an early diagnosis...
December 2023: Curēus
#28
JOURNAL ARTICLE
Daniel J P Burns, Jeevanantham Rajeswaran, Milind Y Desai, A Marc Gillinov, Kevin Hodges, Eric E Roselli, Patrick R Vargo, Lars G Svensson
OBJECTIVE: The study objective was to determine repair durability and survival in patients with and without connective tissue disorders undergoing concomitant aortic valve reimplantation and mitral valve repair. METHODS: From 2002 to 2019, 68 patients underwent concomitant aortic valve reimplantation and mitral valve repair, including 27 patients with Marfan syndrome (39.7%). Follow-up echocardiograms were analyzed using nonlinear multiphase mixed-effects cumulative logistic regression...
December 2023: JTCVS techniques
#29
REVIEW
Parameters of the mitral apparatus in patients with ischemic and nonischemic dilated cardiomyopathy.
João Presume, Mariana S Paiva, Sara Guerreiro, Regina Ribeiras
The mitral valve apparatus is a complex structure consisting of several coordinating components: the annulus , two leaflets, the chordae tendineae, and the papillary muscles. Due to the intricate interplay between the mitral valve and the left ventricle, a disease of the latter may influence the normal function of the former. As a consequence, valve insufficiency may arise despite the absence of organic valve disease. This is designated as functional or secondary mitral regurgitation, and it arises from a series of distortions to the valve components...
December 2023: Journal of International Medical Research
#30
JOURNAL ARTICLE
Firezer Haregu, Ningyan Wong, Michael McCulloch, D Scott Lim
Rigorous clinical trials have demonstrated the safety and efficacy of Transcatheter Edge-to-Edge Repair to treat severe secondary mitral regurgitation (MR) in adults with primary cardiomyopathy who have failed guideline-directed medical therapy, as well as those with primary MR at high surgical risk. To date, there are only three case reports describing this procedure in the pediatric population. We report a case series of four pediatric patients, including the youngest and smallest reported, who underwent this procedure...
December 27, 2023: Pediatric Cardiology
#31
JOURNAL ARTICLE
Kush P Patel, Michael McKenna, George D Thornton, Sebastian Vandermolen, Zaid Ali Abdulelah, Wael Awad, Andreas Baumbach, Anthony Mathur, Thomas A Treibel, Guy Lloyd, Michael J Mullen, Sanjeev Bhattacharyya
OBJECTIVES: Grading the severity of moderate mixed aortic stenosis and regurgitation (MAVD) is challenging and the disease poorly understood. Identifying markers of haemodynamic severity will improve risk stratification and potentially guide timely treatment. This study aims to identify prognostic haemodynamic markers in patients with moderate MAVD. METHODS: Moderate MAVD was defined as coexisting moderate aortic stenosis (aortic valve area (AVA) 1.0-1.5 cm2 ) and moderate aortic regurgitation (vena contracta (VC) 0...
December 26, 2023: Heart
#32
JOURNAL ARTICLE
Constance Delwarde, Claire Toquet, Anne Sophie Boureau, Robin Le Ruz, Solena Le Scouarnec, Jean Mérot, Florence Kyndt, Daniel Bernstein, Jonathan A Bernstein, Jan J J Aalberts, Hervé Le Marec, Jean-Jacques Schott, Jean-Christian Roussel, Thierry Le Tourneau, Romain Capoulade
OBJECTIVE: Variants in the FLNA gene have been associated with mitral valve dystrophy (MVD), and even polyvalvular disease has been reported. This study aimed to analyse the aortic valve and root involvement in FLNA -MVD families and its impact on outcomes. METHODS: 262 subjects (37 (18-53) years, 140 male, 79 carriers: FLNA +) from 4 FLNA -MVD families were included. Echocardiography was performed in 185 patients and histological analysis in 3 explanted aortic valves...
December 26, 2023: Heart
#33
JOURNAL ARTICLE
Liubov R Stetsiuk, Ivan M Klishch, Ihor O Stetsiuk, Borys M Todurov, Mykhailo B Todurov, Larysa Ya Fedoniuk
OBJECTIVE: The aim is to analyze patients with acute myocardial infarction with reduced ejection fraction in order to determine risk factors for mitral insufficiency. PATIENTS AND METHODS: Materials and methods: The study included 149 patients with acute myocardial infarction. Among the patients, there were 113 males (75.8%) and 36 females (24.2%). The age of the patients ranged from 43 to 86 years. Echocardiography was performed using a Phillips Epiq 7 machine...
2023: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
#34
JOURNAL ARTICLE
Kayla Chiew, Ee Ling Heng, Lauren Connolly, Jonathan Byrne, Saib Khogali, Robert Smith
No abstract text is available yet for this article.
December 16, 2023: American Journal of Cardiology
#35
JOURNAL ARTICLE
Tulio Caldonazo, Michel Pompeu Sá, Xander Jacquemyn, Jef Van den Eynde, Hristo Kirov, Lamia Harik, Johannes Fischer, Dominique Vervoort, Johannes Bonatti, Ibrahim Sultan, Torsten Doenst
Mitral valve repair (MVr) has been associated with superior long-term survival and freedom from valve-related complications compared with mitral valve replacement (MVR) for primary mitral regurgitation (MR). The two main approaches for MVr are chordal replacement ("respect approach") and leaflet resection ("resect approach"). We performed a systematic review and a meta-analysis using three search databases to compare long-term endpoints between both approaches. The primary endpoint was long-term survival. The secondary endpoints were long-term MR recurrence and reoperation...
December 15, 2023: American Journal of Cardiology
#36
JOURNAL ARTICLE
Sudipta Mondal, Swasthi S Kumar, Vishnu Kesavan
No abstract text is available yet for this article.
December 15, 2023: Heart
#37
REVIEW
René Ricardo Rodríguez Olivares, José María Carrasco Rueda, José Luis Añorga Ocmin, Carlos Lobato Jerí
In recent decades, the advances in the management of functional mitral regurgitation (MR), makes knowledge of this disease extremely important to the clinical cardiologist, as it has an increasing prevalence in patients older than 50 years. The objective of this article is to review the pathophysiological bases of MR, in order to differentiate its mechanism, and to correlate them with the clinical, hemodynamic, and imaging findings that assess the severity of the disease. These data are relevant for the adequate selection of the patient and the opportune moment of the therapeutic interventions, which involves a multidisciplinary team in decision-making to achieve the greatest benefit within the treatment options of this pathology...
2023: Arch Peru Cardiol Cir Cardiovasc
#38
Xianhong Li, Liying Dai, Jian Zhang
BACKGROUND: Dilated cardiomyopathy (DCM) is a rare disease that causes heart failure due to malfunction of the heart muscle characterized by left ventricular dilation and poor systolic function. Genetic screening leads to advantages in early diagnosis and prognostic assessment of patients with suspected inherited cardiomyopathies. Here, we report a case of neonatal dilated cardiomyopathy due to a mutation of the TNNI3 gene, which has not been published in neonatal dilated cardiomyopathy before...
2023: Frontiers in Pediatrics
#39
JOURNAL ARTICLE
Avik Karak, Novonil Deb, Dibbendu Khanra, Santanu Guha, Anindya Mukherjee
INTRODUCTION: There is insufficient information on the angiographic characteristics of individuals with rheumatic valvular heart disease (VHD) from eastern India. The objective of this research is to gather important data in this area to aid the best surgical outcomes for patients with rheumatic VHD. MATERIALS AND METHODS: 978 consecutive patients with rheumatic VHD, scheduled for surgical intervention, were recruited. RESULT AND CONCLUSION: Mitral valve involvement was observed in 66...
December 1, 2023: Indian Heart Journal
#40
Aamuktha R Karla, Amélie Pinard, Maura L Boerio, Dimitri Hemelsoet, Simon J Tavernier, Michel De Pauw, Elke Vereecke, Stuart Fraser, Michael J Bamshad, Dongchuan Guo, Bert Callewaert, Dianna M Milewicz
Aicardi-Goutières syndrome (AGS) is an autosomal recessive inflammatory syndrome that manifests as an early-onset encephalopathy with both neurologic and extraneurologic clinical findings. AGS has been associated with pathogenic variants in nine genes: TREX1, RNASEH2B, RNASEH2C, RNASEH2A, SAMHD1, ADAR, IFIH1, LSM11, and RNU7-1. Diagnosis is established by clinical findings (encephalopathy and acquired microcephaly, intellectual and physical impairments, dystonia, hepatosplenomegaly, sterile pyrexia, and/or chilblains), characteristic abnormalities on cranial CT (calcification of the basal ganglia and white matter) and MRI (leukodystrophic changes), or the identification of pathogenic/likely pathogenic variants in the known genes...
December 1, 2023: American Journal of Medical Genetics. Part A
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