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Mitral Valve Insufficiency

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https://www.readbyqxmd.com/read/29887228/dose-dependent-effects-of-isoflurane-and-dobutamine-on-cardiovascular-function-in-dogs-with-experimental-mitral-regurgitation
#1
Seijirow Goya, Tomoki Wada, Kazumi Shimada, Daiki Hirao, Ryou Tanaka
OBJECTIVE: To investigate the dose-dependent effects of isoflurane and dobutamine on haemodynamics in dogs with experimentally induced mitral valve insufficiency (MI). STUDY DESIGN: Experimental, dose-response study. ANIMALS: Six healthy Beagle dogs. METHODS: Dogs with surgically induced MI were anaesthetized once. First, anaesthesia was maintained at an end-tidal isoflurane concentration (Fe'Iso) 1.0% (ISO1.0) for 20 minutes...
April 18, 2018: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/29877743/cardioband-system-as-a-treatment-for-functional-mitral-regurgitation
#2
Adolfo Ferrero Guadagnoli, Carlotta De Carlo, Francesco Maisano, Edwin Ho, Matteo Saccocci, Oscar Cuevas, Marco Luciani, Shingo Kuwata, Fabian Nietlispach, Maurizio Taramasso
Are the current data on the Cardioband in the clinical area enough to consider it a tool for mitral regurgitation treatment? Severe secondary mitral valve insufficiency frequently affects high-risk surgical patients. The Cardioband system is a novel percutaneous surgical-like device for direct annuloplasty. It is implanted into the beating heart by transvenous femoral access, with minimal impact on hemodynamic and cardiac function during implantation. So far, it has demonstrated safety and feasibility in high-risk patients with functional mitral regurgitation; it has imparted significant annular reduction and regurgitation improvements...
June 7, 2018: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/29861131/long-term-results-of-mitral-valve-repair-for-severe-mitral-regurgitation-in-asymptomatic-patients
#3
Anton Tomšič, Yasmine L Hiemstra, Fabienne M A van Hout, Thomas J van Brakel, Michel I M Versteegh, Nina Ajmone Marsan, Robert J M Klautz, Meindert Palmen
BACKGROUND: In asymptomatic patients with severe degenerative mitral valve regurgitation (MR), early surgery is often performed in experienced centers. The patient- and valve-related results and the quality of life after surgery in these patients remain insufficiently explored. METHODS: Between 1/2000 and 12/2015, 83 asymptomatic patients (mean age 56.6±12.6 years, 21 female) without any complications related to long-lasting MR underwent early surgery. Follow-up clinical and echocardiographic data and health-related quality of life assessment (SF-36) were studied and matched to the general population...
May 31, 2018: Journal of Cardiology
https://www.readbyqxmd.com/read/29743415/management-of-incomplete-initial-repair-in-the-treatment-of-degenerative-mitral-insufficiency
#4
Wenrui Ma, Wei Shi, Wei Zhang, Weihua Wu, Wei Ye, Ye Kong
We sought to present our institutional protocol to manage incomplete initial repair of degenerative mitral regurgitation and to evaluate its mid-term outcomes. Eight hundred and fifteen patients with degenerative mitral insufficiency undergoing mitral valve repair were investigated in this study. The initial repair attempt was incomplete in 48 patients, leaving a degree of residual regurgitation > mild, and an elevated transmitral gradient or systolic anterior motion (SAM). These patients were further treated with medication or mitral valve re-repair or replacement under reinstituted cardiopulmonary bypass...
May 9, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29730345/hemiarch-reconstruction-vs-clamped-aortic-anastomosis-for-concomitant-ascending-aortic-aneurysm
#5
Ibrahim Sultan, Valentino Bianco, Ibrahim Yajzi, Arman Kilic, Keith Dufendach, Arturo Cardounel, Andrew D Althouse, Ahmad Masri, Forozan Navid, Thomas G Gleason
BACKGROUND: Deep hypothermic circulatory arrest (DHCA) is often avoided in patients with concomitant ascending aortic pathology when treating other cardiac disease to avoid increased risk of morbidity and mortality. We hypothesized that the use of DHCA with retrograde cerebral perfusion (RCP) does not add incremental risk to ascending aortic replacement alone in the setting of concomitant cardiac surgery. METHODS: 408 ascending aortic ± hemiarch replacements and aortic (root)/mitral/tricuspid valve(s), CABG, or MAZE procedures were performed for concomitant cardiac disease...
May 3, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29710128/association-of-timing-of-aortic-valve-replacement-surgery-after-stroke-with-risk-of-recurrent-stroke-and-mortality
#6
Charlotte Andreasen, Mads Emil Jørgensen, Gunnar H Gislason, Andreas Martinsson, Robert D Sanders, Jawdat Abdulla, Per Føge Jensen, Christian Torp-Pedersen, Lars Køber, Charlotte Andersson
Importance: Timing of surgical aortic valve replacement (SAVR) in patients with aortic valve stenosis and previous stroke for the risk of recurrent stroke is insufficiently investigated. Objective: To evaluate the association of time elapsed between previous stroke and SAVR with the risk of recurrent perioperative stroke, major adverse cardiovascular events (MACE), and mortality among patients with aortic valve stenosis. Design, Setting, and Participants: This cohort study using data from Danish administrative registries included all patients with aortic valve stenosis older than 18 years who underwent SAVR between 1996 and 2014 (n = 14 030)...
April 25, 2018: JAMA Cardiology
https://www.readbyqxmd.com/read/29667898/wernicke-s-encephalopathy-after-cardiac-surgery
#7
Yoshiyuki Nishimura
A 76-year-old woman who had been on hemodialysis for 3 years developed ischemic mitral valve insufficiency, tricuspid insufficiency, and chronic atrial fibrillation, and underwent cardiac surgery. On the 4th postoperative day, she experienced a sudden disturbance of consciousness, aphasia, and limb ataxia. Brain computed tomography and magnetic resonance imaging showed no abnormalities. Wernicke's encephalopathy was suspected and the patient was given vitamin B1, whereupon her symptoms gradually improved. On the 42nd postoperative day, she was free of neurological symptoms and discharged...
May 2018: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/29663941/using-the-oculocardiac-reflex-to-characterize-autonomic-imbalance-in-a-naturally-occurring-canine-model-of-valvular-insufficiency
#8
Bruna C Brüler, Thayane C Vieira, Marcela Wolf, Stephany B Lucina, Fabiano Montiani-Ferreira, Marlos G Sousa
Congestive heart failure (CHF) is characterized by reduced heart rate variability. Although various methods to achieve parasympathetic withdrawal and sympathetic activation have been documented, stimulation of the vagal nerve (that is, vagal maneuvers) has not often been used to assess the autonomic impairment associated with disease progression in veterinary species. In this study, we investigated cardiac autonomic control in a naturally occurring canine model of mitral insufficiency by means of individual responses to oculocardiac reflex...
April 2, 2018: Comparative Medicine
https://www.readbyqxmd.com/read/29623557/late-right-ventricular-performance-after-mitral-valve-repair-assessed-by-exercise-echocardiography
#9
Sigurdur Ragnarsson, Johan Sjögren, Martin Stagmo, Per Wierup, Shahab Nozohoor
OBJECTIVES: The aim of the study was to evaluate the right ventricular (RV) performance during exercise in patients who underwent mitral valve repair for chronic mitral valve insufficiency relative to healthy individuals and to assess exercise capacity using a semisupine ergometer. METHODS: We studied 56 patients who underwent mitral valve repair for degenerative posterior mitral leaflet prolapse between 2005 and 2014 and a control group of 13 healthy individuals...
April 5, 2018: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29617977/aortic-sarcoidosis-complicated-by-a-pulmonary-artery-aneurysm
#10
Wataru Uchida, Yoshiyuki Tokuda, Masato Mutsuga, Akihiko Usui
A 76-year-old woman, who had a history of ocular sarcoidosis, was incidentally found to have a huge pulmonary artery aneurysm, along with aortic, mitral and tricuspid valve insufficiency. She underwent pulmonary artery plication along with surgeries for 3 valves. A specimen of the slightly enlarged ascending aorta revealed the involvement of sarcoidosis in the aortic wall. The systemic granulomatous inflammation process of sarcoidosis possibly affected the valvular and vascular pathology. Herein, we report a rare case of aortic sarcoidosis complicated by a pulmonary artery aneurysm...
March 29, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29605416/lyme-endocarditis
#11
Ana C Paim, Larry M Baddour, Bobbi S Pritt, Audrey N Schuetz, John W Wilson
BACKGROUND: Valvular involvement as a manifestation of Lyme carditis is rare. The first case describing a possible association between Lyme disease and cardiac valvular disease in the United States was published in 1993. Since that time there have been 2 cases of Lyme endocarditis confirmed by Borrelia-positive 16S ribosomal RNA polymerase chain reaction and sequencing from valvular tissue and reported from Europe. Here we describe a case of Lyme endocarditis that, to our knowledge, is the first reported case confirmed by molecular diagnostics in the United States...
March 29, 2018: American Journal of Medicine
https://www.readbyqxmd.com/read/29575435/implication-of-pulmonary-hypertension-in-patients-undergoing-mitraclip-therapy-results-from-the-german-transcatheter-mitral-valve-interventions-trami-registry
#12
Eike Tigges, Stefan Blankenberg, R Stephan von Bardeleben, Christine Zürn, Raffi Bekeredjian, Taoufik Ouarrak, Horst Sievert, Georg Nickenig, Peter Boekstegers, Jochen Senges, Wolfgang Schillinger, Edith Lubos
AIMS: We sought to evaluate the impact of pulmonary hypertension on outcomes following MitraClip therapy. METHODS AND RESULTS: The 643 patients in the TRAnscatheter Mitral valve Interventions (TRAMI) registry were divided into three groups according to echocardiographically graded systolic pulmonary artery pressure (sPAP) (Group 1: patients with sPAP of ≤36 mmHg; Group 2: patients with sPAP of 37-50 mmHg; Group 3: patients with sPAP of >50 mmHg) and followed for 1 year...
March 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29507739/normal-function-of-a-43-year-old-braunwald-cutter-heart-valve
#13
Gian Manuel Jiménez-Rodríguez, Sergio Criales-Vera, Mario Adrian Juárez-Peñaloza, Luis Alonso González-Tapia, Mariana Chaire-Hernández
We present the case of a 72-year-old woman diagnosed with rheumatic fever at the age of 6. In 1972, she was diagnosed with mitral valve insufficiency and mitral valve stenosis, then in 1974, a decision was made to perform mitral valve replacement surgery with a 32-mm Braunwald-Cutter ball cage prosthesis. An echocardiogram performed in 2014 revealed normal biventricular systolic function, mechanical prosthesis in mitral position with maximum speed of 1.9 m/s, maximum gradient of 15 mmHg, mean gradient of 6 mmHg, severe tricuspid valve insufficiency, inferior vena cava measuring 15 mm with more than 50% collapse and pulmonary artery systolic pressure of 40 mmHg...
February 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29470257/dynamic-patient-specific-three-dimensional-simulation-of-mitral-repair-can-we-practice-mitral-repair-preoperatively
#14
Olivia K Ginty, John M Moore, Yuanwei Xu, Wenyao Xia, Satoru Fujii, Daniel Bainbridge, Terry M Peters, Bob B Kiaii, Michael W A Chu
OBJECTIVE: Planned mitral repair strategies are generally established from preoperative echocardiography; however, specific details of the repair are often determined intraoperatively. We propose that three-dimensional printed, patient-specific, dynamic mitral valve models may help surgeons plan and trial all the details of a specific patient's mitral repair preoperatively. METHODS: Using preoperative echocardiography, segmentation, modeling software, and three-dimensional printing, we created dynamic, high-fidelity, patient-specific mitral valve models including the subvalvular apparatus...
January 2018: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/29466170/-phenomenological-regularities-of-assessment-of-left-ventricle-function-in-mitral-valve-insufficiency
#15
V A Sandrikov, T Y Kulagina, V A Ivanov, A S Krylov, A M Yatchenko, D R Кhadzhieva, A V Tsyganov, A V Gavrilov, I V Arkhipov
OBJECTIVE: to examine relationship between anatomical changes of the left ventricle (LV), dynamics of velocity of its volume modification, and blood flows in the LV in patients with mitral regurgitation (MR) before and after surgical treatment. MATERIALS AND METHODS: We included into this study 58 patients with severe 3-4 degree MR (38 men, 20 women aged 24-69 [mean age 51±9] years) in sinus rhythm (96 %) or atrial fibrillation (4 %). The control group included 86 healthy volunteers, mean age 39±7 years...
January 2018: Kardiologiia
https://www.readbyqxmd.com/read/29425524/repair-techniques-for-mitral-valve-insufficiency-in-children
#16
REVIEW
Vladimiro L Vida, Lorenza Zanotto, Massimiliano Carrozzini, Massimo A Padalino, Giovanni Stellin
Congenital mitral valve (MV) dysplasia is a relatively rare and highly complex cardiac disease. We sought to provide a comprehensive analysis of the current surgical techniques for treating mitral valve insufficiency and the results of mitral valve repair at our institution. Between 1972 and 2017, 104 consecutive patients underwent surgical repair of congenital MV dysplasia-insufficiency at our institution. Among these, 59 patients presented with MV insufficiency (or prevalent MV insufficiency) and were part of the study...
March 2018: Seminars in Thoracic and Cardiovascular Surgery. Pediatric Cardiac Surgery Annual
https://www.readbyqxmd.com/read/29416208/gigantic-thrombus-of-the-left-atrium-in-mitral-stenosis
#17
Enisa Hodzic, Nermir Granov
Introduction: Excess dilatation of the left atrium >65 mm is known in the literature as gigantic atrium. This dilation is most commonly encountered in the mitral insufficiency of rheumatic etiology, but also in severe prolapses of the mitral valve, permanent atrial fibrillation, and at the left right shunt with cardiac insufficiency. Case report: In this paper is presented a case study of echocardiographically verified giant thrombus in left atrium in a 50 years old female patient aged 50 hospitalized because of tiredness, choking, heartburn and urinary tract symptoms...
December 2017: Medical Archives
https://www.readbyqxmd.com/read/29408404/initial-experience-with-a-new-mitral-ring-designed-to-simplify-length-determination-of-neochords
#18
Anatol Prinzing, Sabine Bleiziffer, Markus Krane, Ruediger Lange
BACKGROUND: Artificial chord implantation has become one of the most applied techniques for mitral valve repair (MVR). Many techniques have been described with the goal of optimizing neochord implantation. A new annuloplasty device designed to simplify the determination of appropriate neochord length has been recently introduced. We will describe our initial experience with this new device. METHODS: The semirigid device is equipped with removable loops on the posterior aspect of the ring...
February 3, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29397472/gastrointestinal-bleeding-in-native-and-prosthetic-valve-disease
#19
REVIEW
Joseph L Blackshear
Gastrointestinal bleeding with severe aortic stenosis was originally described in the 1950s by Heyde, although for years, the association was debated. Further discovery of mechanisms and the ubiquity and severity of acquired von Willebrand syndrome in the left ventricular assist device therapy have removed any doubts. At this time, gastrointestinal bleeding from intestinal angiodysplasia in patients with turbulence-related proteolysis of the highest molecular weight multimers of von Willebrand factor is now known to occur in patients with aortic stenosis, and also subaortic obstruction and associated mitral insufficiency in hypertrophic cardiomyopathy, isolated mitral and aortic insufficiency, endocarditis, and in patients with prosthetic valve dysfunction, either from stenosis or insufficiency...
February 3, 2018: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29334508/practical-valvular-issues-in-patients-requiring-ventricular-assist-devices
#20
Mitesh Badiwala, Terrence Yau
PURPOSE OF REVIEW: As ventricular assist device (VAD) therapy in patients with advanced heart failure continues to grow, experience with concomitant valvular diseases present either before or after VAD implantation continues to accrue. In this review, we discuss recent data and current practice as it pertains to the subject of concomitant valvular disease in patients requiring VADs. RECENT FINDINGS: Persistent aortic valve closure has been identified as a potential contributor to aortic valve 'disuse atrophy' resulting in valve degeneration...
March 2018: Current Opinion in Cardiology
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