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https://www.readbyqxmd.com/read/28095338/docosahexaenoic-acid-attenuates-lps-stimulated-inflammatory-response-by-regulating-the-ppar%C3%AE-nf-%C3%AE%C2%BAb-pathways-in-primary-bovine-mammary-epithelial-cells
#1
REVIEW
Xuexiu He, Weijian Liu, Mingyu Shi, Zhengtao Yang, Xichen Zhang, Pengtao Gong
BACKGROUND: Docosahexaenoic acid (DHA) is a major dietary n-3 polyunsaturated fatty acid (n-3 PUFA) in fish oil, and has been reported to possess a number of biological properties, such as anti-inflammatory, antitumor and immune-regulatory properties. However, whether DHA exert anti-inflammatory effect on lipopolysaccharide (LPS)-induced mastitis remains unclear. In this study, we investigate the effect and underlying mechanisms of the effects of DHA on LPS-stimulated primary bovine mammary epithelial cells (bMEC)...
January 5, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28088425/short-communication-staphylococcus-aureus-infection-modulates-expression-of-drug-transporters-and-inflammatory-biomarkers-in-mouse-mammary-gland
#2
A Oskarsson, Y Yagdiran, S Nazemi, J Tallkvist, C H Knight
Mastitis is the most common disease in dairy herds worldwide and is often caused by Staphylococcus aureus. Little is known about the effect of mastitis on transporters in the mammary gland and the effect on transporter-mediated secretion of drugs into milk. We studied gene expressions of ATP-binding cassette and solute carrier transporters in S. aureus-infected mammary glands of mice. On d 7 of lactation, NMRI mice were inoculated with 1,000 cfu of S. aureus in 2 mammary glands and with a saline vehicle in 2 control glands...
January 11, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28077102/effects-of-aqueous-extracts-of-taraxacum-officinale-on-expression-of-tumor-necrosis-factor-alpha-and-intracellular-adhesion-molecule-1-in-lps-stimulated-rmmvecs
#3
Ge Hu, Junjie Wang, Dong Hong, Tao Zhang, Huiqin Duan, Xiang Mu, Zuojun Yang
BACKGROUND: Mastitis gives rise to big financial burden to farm industry (mainly dairy production) and public health. Its incidence is currently high and therefore, highly effective treatments for therapy, especially with natural products are required. Taraxacum officinale has been reported to use for anti-inflammation. However, its effect on endothelium during mastitis has not been reported. METHODS: We firstly established inflammation experimental model of rat mammary microvascular endothelial cells (RMMVECs)...
January 11, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28065639/imaging-features-and-diagnosis-of-tuberculosis-of%C3%A2-the-breast
#4
C F Longman, T Campion, B Butler, T D Suaris, A Khanam, H Kunst, S Tiberi, S A O'Keeffe
AIM: To outline the pathophysiology, clinical presentation, imaging features, and relevant investigations of the different subtypes of breast tuberculosis (TB). MATERIALS AND METHODS: A review was undertaken of all cases (33 in total) of breast TB presenting to Barts Health NHS Trust within a 10-year period, including patient demographics, imaging features, and route of diagnosis. RESULTS: Thirty-three cases of proven granulomatous TB of the breast were identified (11 mastitis obliterans, 10 nodular caseous form, five sclerosing form, four disseminated disease, and three abnormal axillary lymph nodes)...
January 6, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28050664/rifampicin-for-idiopathic-granulomatous-lobular-mastitis-a-promising-alternative-for-treatment
#5
Omar Farouk, Mohamed Abdelkhalek, Ahmed Abdallah, Ahmed Shata, Ahmed Senbel, Essam Attia, Mohamed Abd Elghaffar, Mahmoud Mesbah, Nermine Soliman, Maha Amin, Dina El-Tantawy
BACKGROUND: Idiopathic granulomatous lobular mastitis (IGLM) is a chronic, non-caseating, inflammatory breast disease of obscure aetiology characterized by multiple masses, abscesses and sinus formation. There is no standard treatment to date, but surgical procedures and systemic corticosteroids are effective in its treatment despite high recurrence rates. PATIENTS AND METHODS: This prospective study including 30 patients with IGLM between November 2012 and May 2016 aimed to investigate the possibility of administration of Rifampicin (300 mg twice daily for a period of 6-9 months) as an alternative therapy for both surgery and corticosteroids in patients with IGLM...
January 3, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28012631/estimating-us-dairy-clinical-disease-costs-with-a-stochastic-simulation-model
#6
D Liang, L M Arnold, C J Stowe, R J Harmon, J M Bewley
A farm-level stochastic model was used to estimate costs of 7 common clinical diseases in the United States: mastitis, lameness, metritis, retained placenta, left-displaced abomasum, ketosis, and hypocalcemia. The total disease costs were divided into 7 categories: veterinary and treatment, producer labor, milk loss, discarded milk, culling cost, extended days open, and on-farm death. A Monte Carlo simulation with 5,000 iterations was applied to the model to account for inherent system variation. Four types of market prices (milk, feed, slaughter, and replacement cow) and 3 herd-performance factors (rolling herd average, product of heat detection rate and conception rate, and age at first calving) were modeled stochastically...
December 21, 2016: Journal of Dairy Science
https://www.readbyqxmd.com/read/28007038/semi-quantitative-method-for-staphylococci-magnetic-detection-in-raw-milk
#7
Carla Margarida Duarte, Carla Carneiro, Susana Cardoso, Paulo Peixeiro Freitas, Ricardo Bexiga
Bovine mastitis is the most costly disease for dairy farmers, hence, control measures to prevent it are crucial for dairy farm sustainability. Staphylococcus aureus is considered a major mastitis pathogen because of its impact on milk quality and low cure rates. Prevention of S. aureus mastitis includes segregation of infected animals, whilst treatment of such animals should be performed for a longer time to improve cure rates. This makes identification of S. aureus infected quarters and animals of significant importance...
December 23, 2016: Journal of Dairy Research
https://www.readbyqxmd.com/read/27984712/mangiferin-inhibits-mastitis-induced-by-lps-via-suppressing-nf-%C3%A4-b-and-nlrp3-signaling-pathways
#8
Shihui Qu, Wenqing Wang, Depeng Li, Shumin Li, Like Zhang, Yunhe Fu, Naisheng Zhang
During the past era, small molecules derived from various plants have attracted extensive attention for their versatile medicinal benefits. Among these, one organic molecule called mangiferin from certain plant species including mangoes and honey bush tea is widely used in treating inflammation. In this study, a LPS-induced mastitis model in mouse is established to investigate the anti-inflammatory effects and mechanism of mangiferin. The result shows that mangiferin significantly alleviates LPS-induced histopathology, meanwhile, also decreases LPS-induced MPO activity...
February 2017: International Immunopharmacology
https://www.readbyqxmd.com/read/27939551/antimicrobial-treatment-of-clinical-mastitis-in-the-eastern-united-states-the-influence-of-dairy-farmers-mastitis-management-and-treatment-behavior-and-attitudes
#9
J Kayitsinga, R L Schewe, G A Contreras, R J Erskine
To assess both the behaviors and social variables related to antimicrobial therapy for clinical mastitis, we sent a survey to 1,700 dairy farms in Michigan, Pennsylvania, and Florida in January and February 2013. The survey included questions related to 7 major areas: sociodemographic and farm characteristics, milking proficiency, milking systems, cow environment, infected cow monitoring and treatment, farm labor, and attitudes toward mastitis and related antimicrobial use. The overall response rate was 41% (21% in Florida, 39% in Michigan, and 45% in Pennsylvania)...
December 8, 2016: Journal of Dairy Science
https://www.readbyqxmd.com/read/27939157/a-dominant-lineage-of-mycoplasma-bovis-is-associated-with-an-increased-number-of-severe-mastitis-cases-in-cattle
#10
Sibylle Bürki, Joachim Spergser, Michèle Bodmer, Paola Pilo
Mycoplasma bovis is the most frequent etiologic agent of bovine mycoplasmosis. It causes various diseases in bovines and considerable economic loss due to the lack of effective treatment or preventive measures such as vaccination. In contrast to the US, where M. bovis-mastitis has been reported for a long time, M. bovis infections in Switzerland and Austria were predominantly associated with pneumonia and subclinical mastitis. However, since 2007 the situation has changed with the emergence of severe M. bovis-associated mastitis cases in both countries...
November 30, 2016: Veterinary Microbiology
https://www.readbyqxmd.com/read/27939148/detection-of-the-biofilm-component-polysaccharide-intercellular-adhesin-in-staphylococcus-aureus-infected-cow-udders
#11
Sarah Schönborn, Volker Krömker
Biofilms are communities of microorganisms embedded in a self-produced extracellular matrix made up of polymeric substances. They reduce the effects of antibiotics and allow the microorganisms to evade the innate immune system. This can lead to persistent or recurrent infections. In dairy cow herds, mastitis is a serious problem. The present study aimed to investigate the occurrence of biofilms in the udders of dairy cows infected with Staphylococcus (S.) aureus, because biofilms may affect the response to treatment of bovine mastitis...
November 30, 2016: Veterinary Microbiology
https://www.readbyqxmd.com/read/27938408/mammary-inflammatory-gene-expression-was-associated-with-reproductive-stage-and-regulated-by-docosahexenoic-acid-in-vitro-and-in-vivo-studies
#12
Sen Lin, Yalin Zhang, Yanrong Long, Haifeng Wan, Lianqiang Che, Yan Lin, Shengyu Xu, Bin Feng, Jian Li, De Wu, Zhengfeng Fang
BACKGROUND: Periparturient mastitis is the most prevalent disease affecting lactating animals. However, it has long been relied on antibiotics to deal with mastitis, leading to a potential threat to food safety. This study was aimed to investigate the expression of pro-inflammatory cytokines in mammary glands of sows around parturition when mastitis and oxidative stress usually occur, and evaluate the anti-inflammatory effect of docosahexenoic acid (DHA) in porcine mammary epithelial cells (PMEC) challenged by lipopolysaccharide (LPS)...
December 9, 2016: Lipids in Health and Disease
https://www.readbyqxmd.com/read/27922724/antenatal-breastfeeding-education-for-increasing-breastfeeding-duration
#13
REVIEW
Pisake Lumbiganon, Ruth Martis, Malinee Laopaiboon, Mario R Festin, Jacqueline J Ho, Mohammad Hakimi
BACKGROUND: Breast milk is well recognised as the best food source for infants. The impact of antenatal breastfeeding (BF) education on the duration of BF has not been evaluated. OBJECTIVES: To assess the effectiveness of antenatal breastfeeding (BF) education for increasing BF initiation and duration. SEARCH METHODS: We searched Cochrane Pregnancy and Childbirth's Trials Register on 1 March 2016, CENTRAL (The Cochrane Library, 2016, Issue 3), MEDLINE (1966 to 1 March 2016) and Scopus (January 1985 to 1 March 2016)...
6, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27905374/-diagnosis-and-treatment-of-inflammatory-diseases-of-the-mammary-ducts
#14
G A Belonenko, A G Grintsov, A G Osipov, G G Pilyugin, Yu G Lutsenko, E G Aksenova, A A Aksenov
AIM: The analysis and popularization of the own experience of ultrasonic diagnostics and minimal invasive interventions for inflammatory diseases of the mammary ducts. PATIENTS AND METHODS: 249 women were observed: 182 (73.1%) cases of periductal mastitis and 67 (26.9%) cases of purulent galactophoritis. Patients with purulent galactophoritis were divided into 2 groups (main and control). The main group consisted of 50 patients after minimal invasive interventions, control - 17 women after traditional surgery...
2016: Khirurgiia
https://www.readbyqxmd.com/read/27890916/polydatin-ameliorates-staphylococcus-aureus-induced-mastitis-in-mice-via-inhibiting-tlr2-mediated-activation-of-the-p38-mapk-nf-%C3%AE%C2%BAb-pathway
#15
Kang-Feng Jiang, Gan Zhao, Gan-Zhen Deng, Hai-Chong Wu, Nan-Nan Yin, Xiu-Ying Chen, Chang-Wei Qiu, Xiu-Li Peng
Recent studies show that Polydatin (PD) extracted from the roots of Polygonum cuspidatum Sieb, a widely used traditional Chinese remedies, possesses anti-inflammatory activity in several experimental models. In this study, we investigated the anti-inflammatory effects of PD on Staphylococcus aureus-induced mastitis in mice and elucidated the potential mechanisms. In mice with S aureus-induced mastitis, administration of PD (15, 30, 45 mg/kg, ip) or dexamethasone (Dex, 5 mg/kg, ip) significantly suppressed the infiltration of inflammatory cells, ameliorated the mammary structural damage, and inhibited the activity of myeloperoxidase, a biomarker of neutrophils accumulation...
November 28, 2016: Acta Pharmacologica Sinica
https://www.readbyqxmd.com/read/27882115/retrospective-analysis-of-seven-breast-tuberculosis-cases
#16
Beyhan Çakar, Aydin Çiledağ
The present study aimed to evaluate the demographic data, diagnostic methods, therapeutic regimens and duration of therapy in 7 breast tuberculosis (BTB) cases. The data of BTB cases treated between January 2006 and December 2013 were retrospectively evaluated, with a total of 648 tuberculosis (TB) cases recorded during the 8-year period. Among these cases, 296 patients (50%) suffered from pulmonary TB, 278 (43%) from non-pulmonary TB and 45 (7%) from PTB plus NPTB. In total, 7 BTB were diagnosed, which constituted 1...
November 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27874095/longitudinal-metagenomic-profiling-of-bovine-milk-to-assess-the-impact-of-intramammary-treatment-using-a-third-generation-cephalosporin
#17
Erika K Ganda, Rafael S Bisinotto, Svetlana F Lima, Kristina Kronauer, Dean H Decter, Georgios Oikonomou, Ynte H Schukken, Rodrigo C Bicalho
Antimicrobial usage in food animals has a direct impact on human health, and approximately 80% of the antibiotics prescribed in the dairy industry are used to treat bovine mastitis. Here we provide a longitudinal description of the changes in the microbiome of milk that are associated with mastitis and antimicrobial therapy. Next-generation sequencing, 16 S rRNA gene quantitative real-time PCR, and aerobic culturing were applied to assess the effect of disease and antibiotic therapy on the milk microbiome...
November 22, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27872722/production-of-monoclonal-antibody-against-recombinant-ns3-protein-of-bovine-viral-diarrhea-virus-nadl-strain
#18
Masood Reza Seyfi Abad Shapouri, Maryam Ekhtelat, Masood Ghorbanpoor Najaf Abadi, Mohsen Lotfi, Mohamad Rashno
This study was conducted to investigate the prevalence of subclinical mastitis caused by Staphylococcus spp. in ewes in West-Azerbaijan province of Iran. Molecular characterization of isolated Staphylococcus spp. from diseased ewes were performed using polymerase chain reaction (PCR) followed by restriction fragment length polymorphism (RFLP) and DNA sequencing of glyceraldehyde-3-phosphate dehydrogenase (gap) gene. Also, antibiotic resistance of staphylococcal isolates against different antibiotics was investigated...
2016: Veterinary Research Forum
https://www.readbyqxmd.com/read/27871373/design-and-production-of-antibodies-for-the-detection-of-streptococcus-uberis
#19
K Mihklepp, K Kivirand, M Nikopensius, D Peedel, M Utt, T Rinken
Streptococcus uberis (S. uberis) is an important environmental pathogen causing mastitis in dairy cattle. Mastitis or mammary gland infection is the most common disease in milking cows and cause significant economic burden to farmers due to the reduction of the amount of milk and its quality. The development of rapid analytical methods for the determination of mastitis-causing pathogens in milk is of utmost importance for the early identification of the causes of mastitis and the beginning of timely treatment of cows...
January 2017: Enzyme and Microbial Technology
https://www.readbyqxmd.com/read/27865491/prevalence-and-risk-factors-for-extended-spectrum-%C3%AE-lactamase-or-ampc-producing-escherichia-coli-in-organic-dairy-herds-in-the-netherlands
#20
I M G A Santman-Berends, M A Gonggrijp, J J Hage, A E Heuvelink, A Velthuis, T J G M Lam, G van Schaik
Extended-spectrum β-lactamase and AmpC-producing Escherichia coli (ESBL/AmpC) are an emerging problem and are hypothesized to be associated with antimicrobial use (AMU), and more specifically with the use of third- and fourth-generation cephalosporins. Whether ESBL/AmpC also occur in organic dairy herds, which have restricted AMU, is not known. Additionally, it is unknown whether, in addition to restricted AMU, other factors in organic herd management are associated with ESBL/AmpC herd status. The aim of this study was to estimate the prevalence of ESBL/AmpC in organic dairy herds in the Netherlands...
January 2017: Journal of Dairy Science
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