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https://www.readbyqxmd.com/read/29236301/synergistic-effect-of-carnosine-on-browning-of-adipose-tissue-in-exercised-obese-rats-a-focus-on-circulating-irisin-levels
#1
Mona F Schaalan, Basma K Ramadan, Azza H Abd Elwahab
BACKGROUND: The recent appreciation of the energy burning capacity of brown adipose tissue turns it to an attractive target as anti-obesity therapy. OBJECTIVE: to evaluate the effect of L-carnosine on browning of white adipose tissue in exercised obese rats. METHODS: Sixty adult male Wistar albino rats between 7-8 weeks-old weighing 130-150 g were allocated into six groups;(i) normal control rats fed normal diet; (ii) high fat diet (HFD)-induced obese rats, (iii) normal control rats fed normal diet and injected with L-carnosine (250mg/kg), (iv) HFD-rats injected with L-carnosine (250mg/kg),(v): HFD-rats subjected to exercise training; (vi): HFD- rats subjected to exercise training and L-carnosine together...
December 13, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29236164/the-influence-of-isoflavone-for-denervation-induced-muscle-atrophy
#2
Shinpei Tabata, Miki Aizawa, Masakazu Kinoshita, Yoshinori Ito, Yusuke Kawamura, Minoru Takebe, Weijun Pan, Kunihiro Sakuma
PURPOSE: Decrease in activity stress induces skeletal muscle atrophy. A previous study showed that treatment with a high level (20%) of isoflavone inhibits muscle atrophy after short-term denervation (at 4 days) in mice. The present study was designed to elucidate whether the dietary isoflavone aglycone (AglyMax) at a 0.6% prevents denervation-mediated muscle atrophy, based on the modulation of atrogin-1- or apoptosis-dependent signaling. METHODS: Mice were fed either a normal diet or 0...
December 13, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/29236119/estimation-of-the-bioaccessibility-and-bioavailability-of-fe-mn-cu-and-zn-in-chinese-vegetables-using-the-in-vitro-digestion-caco-2-cell-model-the-influence-of-gut-microbiota
#3
Xiaolin Cai, Xiaochen Chen, Naiyi Yin, Huili Du, Guoxin Sun, Lihong Wang, Yudong Xu, Yuqing Chen, Yanshan Cui
The influence of the human gut microbiota on the bioaccessibility and bioavailability of trace elements in vegetables has barely been studied. An in vitro digestion model combining the physiologically based extraction test (PBET) and the Simulator of Human Intestinal Microbial Ecosystem (SHIME) was applied. Results showed that the gut microbiota increased the bioaccessibility of iron (Fe) in ten test vegetables by 1.3-1.8 times, but reduced the bioaccessibility of manganese (Mn), copper (Cu), and zinc (Zn) in vegetables in the colon phase by 3...
December 13, 2017: Food & Function
https://www.readbyqxmd.com/read/29236075/risks-and-benefits-of-increased-nut-consumption-cardiovascular-health-benefits-outweigh-the-burden-of-carcinogenic-effects-attributed-to-aflatoxin-b%C3%A2-exposure
#4
Hanna Eneroth, Stina Wallin, Karin Leander, Johan Nilsson Sommar, Agneta Åkesson
Nuts are rich in nutrients and mounting evidence shows that consumption reduces cardiovascular disease (CVD) incidence. Nuts may also be a major source of aflatoxin B₁, a potent liver carcinogen and the risk/benefit balance is unknown. Based on national statistics and data from the PREDIMED intervention trial, we estimated the potential CVD-reduction if Swedes aged 55-79 consumed 30 g nuts/day, instead of the current national average of five grams per day. We also assessed the reduction in disability-adjusted life years (DALYs) due to myocardial infarction (MI) and stroke...
December 13, 2017: Nutrients
https://www.readbyqxmd.com/read/29235703/characteristics-of-healthy-weight-advertisements-in-three-countries
#5
Simone Pettigrew, Zenobia Talati, Isla Henriques, Belinda Morley, Kylie Ball
OBJECTIVE: High rates of population obesity have resulted in the dissemination of mass media campaigns that focus on achieving and maintaining a healthy weight. The aim of the present study was to analyse advertising techniques used in such campaigns to identify common and differential approaches in three countries with similar cultures and rates of obesity (Australia, the United Kingdom and the United States). METHODS: An Internet search was conducted to identify healthy weight television advertisements aired in the three countries...
December 13, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/29235585/corrigendum-to-antihypercholesterolemic-effects-of-fruit-aqueous-extract-of-copernicia-prunifera-miller-h-e-moore-in-mice-diet-induced-hypercholesterolemia
#6
Raquel Teixeira Terceiro Paim, Stephen Rathinaraj Benjamin, Davide Rondina, Márcia Maria Mendes Marques, Daniel de Araújo Viana, Maria Leônia da Costa Gonzaga, Ícaro Gusmão Pinto Vieira, Francisca Noélia Pereira Mendes, Paula Alves Salmito Rodrigues, Maria Izabel Florindo Guedes
[This corrects the article DOI: 10.1155/2017/6376173.].
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29235214/the-effect-of-administration-of-copper-nanoparticles-to-chickens-in-their-drinking-water-on-the-immune-and-antioxidant-status-of-the-blood
#7
Katarzyna Ognik, Iwona Sembratowicz, Ewelina Cholewińska, Jan Jankowski, Krzysztof Kozłowski, Jerzy Juśkiewicz, Zenon Zduńczyk
The aim of this experiment was to determine what dosage of copper (Cu) nanoparticles, added to a standard dietary supplementation with copper sulfate, would improve antioxidant and immune defense in chickens. The experiment was conducted with 126 broiler chickens assigned to seven treatments with three pens per treatment and six broiler chickens per pen. The basal-diet treatment did not receive Cu nanoparticles (nano-Cu) and as shown by analyses it was Cu-deficient (-29% vs. National Research Council (NRC) recommendations; 5...
December 12, 2017: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/29235157/dietary-intake-in-people-consuming-a-low-carbohydrate-diet-in-the-uk-biobank
#8
M Shafique, S Russell, S Murdoch, J D Bell, N Guess
BACKGROUND: Low-carbohydrate diets are becoming increasingly popular, although their dietary quality outside of clinical studies is unknown. A previous study analysed the dietary intake in people consuming a reduced-carbohydrate diet (<40% calories). However, it is not clear what foods people consume when carbohydrate is reduced to below 26% of total calories. METHODS: In the present cross-sectional study, the dietary and nutrient intake collected via up to five consecutive 24-h dietary recalls and a food frequency questionnaire of 444 individuals (aged 46-79 years) consuming <26% of calories from carbohydrate (LCHO) was compared with that of 131 897 individuals consuming ≥45% calories from carbohydrate (NCHO) using the UK Biobank Dataset...
December 13, 2017: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
https://www.readbyqxmd.com/read/29235103/dietary-patterns-and-risk-of-recurrence-and-progression-in-non-muscle-invasive-bladder-cancer
#9
Ellen Westhoff, Xifeng Wu, Lambertus A Kiemeney, Seth P Lerner, Yuanqing Ye, Maosheng Huang, Colin P Dinney, Alina Vrieling, Huakang Tu
The association of dietary factors with urinary bladder cancer prognosis has scarcely been investigated, and results of studies conducted to date are inconsistent. We investigated whether empirically derived dietary patterns are associated with risks of recurrence and progression in non-muscle invasive bladder cancer patients. Data from 595 newly diagnosed non-muscle-invasive bladder cancer patients from an ongoing prospective cohort study were used to derive dietary patterns using exploratory factor analysis...
December 13, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29235101/aquatic-food-web-dynamics-following-incorporation-of-nutrients-derived-from-atlantic-anadromous-fishes
#10
K M Samways, D X Soto, R A Cunjak
Changes in the isotopic composition (δ13 C and δ15 N) in biofilm, macro-invertebrates and resident salmonids were used to characterize temporal dynamics of marine derived nutrients (MDNs) incorporation between stream reaches with and without MDN inputs. Five Atlantic rivers were chosen to represent contrasting MDN subsidies: four rivers with considerable numbers of anadromous fishes; one river with little MDN input. Rainbow smelt Osmerus mordax, alewife Alosa pseudoharengus, sea lamprey Petromyzon marinus and Atlantic salmon Salmo salar, were the primary anadromous species for the sampled rivers...
December 12, 2017: Journal of Fish Biology
https://www.readbyqxmd.com/read/29235048/serum-lipid-enzyme-and-hematological-responses-of-broilers-fed-acacia-angustissima-leaf-meal-based-diets
#11
Sharai Ncube, Petronella Tapiwa Saidi, Musavengana Tapera Tivapasi, Venancio Edward Imbayarwo-Chikosi, Tinyiko Edward Halimani
The objective of the study was to determine serum lipid, enzyme, and hematological responses of broilers to Acacia angustissima leaf meal. Acacia angustissima leaves were harvested at mid maturity, ground into a leaf meal, and included in broiler diets at 0, 5, and 10%. One hundred and fifty-day-old chicks of 41.7 ± 1.560 g were randomly allocated to 15 groups of the three diets. Feed and water were provided ad libitum throughout the trial. At days 14, 28, and 42, 4 ml of blood were collected from the jugular vein in plain vacutainer tubes for alanine aminotransferase (ALT), alkaline phosphatase (ALP), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and total cholesterol (TC) analyses...
December 12, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/29235014/increased-bile-acid-signals-after-duodenal-jejunal-bypass-improve-non-alcoholic-steatohepatitis-nash-in-a-rodent-model-of-diet-induced-nash
#12
Takahiro Tsuchiya, Takeshi Naitoh, Munenori Nagao, Naoki Tanaka, Kazuhiro Watanabe, Hirofumi Imoto, Tomohiro Miyachi, Fuyuhiko Motoi, Michiaki Unno
BACKGROUND: The increasing incidence of non-alcoholic steatohepatitis (NASH) has resulted in it becoming a common cause of liver-related mortality; however, no efficient treatment has been established. It has been reported that bariatric surgery improves metabolic comorbidities, such as diabetes mellitus and NASH. Although the mechanism is unclear, it is thought that the changes in bile acid (BA) signaling via its nuclear receptor, farnesoid X receptor (FXR), produce various metabolic effects...
December 12, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/29235012/implications-of-celiac-disease-among-patients-undergoing-gastric-bypass
#13
Lindsey M Freeman, Andrew T Strong, Gautam Sharma, Suriya Punchai, John H Rodriguez, Donald F Kirby, Matthew Kroh
INTRODUCTION: Bariatric surgery is generally safe and effective, but co-existing malabsorptive processes may increase the risk of complications or nutritional deficiencies. Bariatric surgery has not been well studied in the setting of pre-existing celiac disease. MATERIALS AND METHODS: Patients who underwent Roux-en-Y gastric bypass (RYGB) from January 2002 to December 2015 were retrospectively reviewed for either diagnosis of or serum testing for celiac disease...
December 12, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/29234969/monoclonal-antibodies-for-treatment-of-eosinophilic-esophagitis
#14
REVIEW
Mahsa Eskian, MirHojjat Khorasanizadeh, Amal H Assa'ad, Nima Rezaei
Eosinophilic esophagitis (EoE) is a chronic inflammatory disease of the esophagus affecting both children and adults, with debilitating and progressive symptoms. EoE has shown an explosive epidemiological rise in the past few decades. Many patients experience a poor level of disease control despite maximal use of available guideline-based therapies, which seriously hampers their quality of life. Diet restrictions and systemic and topical corticosteroids are the current mainstays of EoE therapy, but are associated with significant efficacy, treatment compliance, and safety issues such as oral or esophageal candidiasis, growth retardation, osteopenia, osteoporosis, glucose intolerance, and cataract formation...
December 12, 2017: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/29234934/early-detection-of-left-ventricular-diastolic-dysfunction-using-conventional-and-speckle-tracking-echocardiography-in-a-large-animal-model-of-metabolic-dysfunction
#15
Mark M P van den Dorpel, Ilkka Heinonen, Sanne M Snelder, Hendrik J Vos, Oana Sorop, Ron T van Domburg, Daphne Merkus, Dirk J Duncker, Bas M van Dalen
Left ventricular (LV) diastolic dysfunction is one of the important mechanisms responsible for symptoms in patients with heart failure. The aim of the current study was to identify parameters that may be used to detect early signs of LV diastolic dysfunction in diabetic pigs on a high fat diet, using conventional and speckle tracking echocardiography. The study population consisted of 16 healthy Göttingen minipigs and 18 minipigs with experimentally induced metabolic dysfunction. Echocardiography measurements were performed at baseline and 3-month follow-up...
December 12, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29234684/changes-in-the-diaphragm-lipid-content-after-administration-of-streptozotocin-and-high-fat-diet-regime
#16
Bartlomiej Lukaszuk, Agnieszka Miklosz, Malgorzata Zendzian-Piotrowska, Beata Wojcik, Jan Gorski, Adrian Chabowski
The diaphragm is a dome-shaped skeletal muscle indispensable for breathing. Its activity contributes up to 70% of the total ventilatory function at rest. In comparison to other skeletal muscles, it is distinguished by an oxidative phenotype and uninterrupted cyclic contraction pattern. Surprisingly, the research regarding diaphragm diabetic phenotype particularly in the light of lipid-induced insulin resistance is virtually nonexistent. Male Wistar rats were randomly allocated into 3 groups: control, streptozotocin-induced (STZ) type-1 diabetes, and rodents fed with high-fat diet (HFD)...
2017: Journal of Diabetes Research
https://www.readbyqxmd.com/read/29234452/genetic-variations-of-cholesteryl-ester-transfer-protein-and-diet-interactions-in-relation-to-lipid-profiles-and-coronary-heart-disease-a-systematic-review
#17
REVIEW
Parvin Mirmiran, Zohre Esfandiar, Firoozeh Hosseini-Esfahani, Gelareh Koochakpoor, Maryam S Daneshpour, Bahar Sedaghati-Khayat, Fereidoun Azizi
Data on diet-genotype interactions in the prevention or treatment of dyslipidemia have increased remarkably. This systematic review aimed to assess nutrigenetic studies regarding the modulating effect of diet on cholesteryl ester transfer protein (CETP) polymorphisms in relation to metabolic traits. Data were collected through studies published between 2000 and SEP. 2016 using five electronic databases. The quality of eligible studies was assessed using a 12-item quality checklist, derived from the STrengthening the REporting of Genetic Association Studies (STREGA) statement...
2017: Nutrition & Metabolism
https://www.readbyqxmd.com/read/29234441/euphorbia-kansui-attenuates-insulin-resistance-in-obese-human-subjects-and-high-fat-diet-induced-obese-mice
#18
Seung-Wook Lee, Hyun-Young Na, Mi Hyeon Seol, Mia Kim, Byung-Cheol Lee
Background: Obesity is a main cause of insulin resistance (IR), metabolic syndrome, and fatty liver diseases. This study evaluated Euphorbia kansui radix (Euphorbia) as a potential treatment option for obesity and obesity-induced IR in obese human and high-fat diet- (HFD-) induced obese mice. Methods: In the human study, we analyzed the body weight change of 14 patients who took a single dose of 6 g of Euphorbia powder. In the animal study, male mice were divided into three groups: normal chow, HFD, and Euphorbia (high-fat diet and 100 mg/Kg Euphorbia once per week)...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29234430/antidyslipidemic-anti-inflammatory-and-antioxidant-activities-of-aqueous-leaf-extract-of-dioscoreophyllum-cumminsii-stapf-diels-in-high-fat-diet-fed-rats
#19
O B Ibitoye, U M Ghali, J B Adekunle, J N Uwazie, T O Ajiboye
Dioscoreophyllum cumminsii (Stapf) Diels leaves are widely used in the treatment of diabetes, obesity, and cardiovascular related complications in Nigeria. This study investigates the anti-inflammatory and antiobesity effect of aqueous extract of Dioscoreophyllum cumminsii leaves in high-fat diet- (HFD-) induced obese rats. HFD-fed rats were given 100, 200, and 400 mgkg-1 body weight of aqueous extract of Dioscoreophyllum cumminsii leaves for 4 weeks starting from 9th week of HFD treatment. D. cumminsii leaves aqueous extract reversed HFD-mediated decrease in the activities of superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, and glucose 6-phosphate dehydrogenase...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29234419/effect-of-sheng-jiang-powder-on-obesity-induced-multiple-organ-injuries-in-rats
#20
Juan Li, Yu-Mei Zhang, Jun-Yi Li, Lv Zhu, Hong-Xin Kang, Hong-Yu Ren, Huan Chen, Ling Yuan, Yi-Fan Miao, Mei-Hua Wan, Wen-Fu Tang
Background and Aims: Obesity has become the main public health issue nowadays with poor control and has been associated with increased risk of multiorgan disease, but the specific mechanism and effective medication are still to be addressed. Sheng-jiang powder (SJP) showed great potential in preventing obesity in Chinese researches but has no trace in English reports. This study was designed to investigate the effect of SJP on obesity and obesity-mediated multiorgan injuries. Methods: Rats were randomized into normal group (NG), obese group (OG), and SJP treatment group (SG)...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
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