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https://www.readbyqxmd.com/read/29611031/metabolomics-study-of-immune-responses-of-new-zealand-greenshell%C3%A2-mussels-perna-canaliculus-infected-with-pathogenic-vibrio-sp
#1
Thao V Nguyen, Andrea C Alfaro, Tim Young, Sridevi Ravi, Fabrice Merien
Vibrio coralliilyticus is a bacterial pathogen which can affect a range of marine organisms, such as corals, fish and shellfish, with sometimes devastating consequences. However, little is known about the mechanisms involved in the host-pathogen interaction, especially within molluscan models. We applied gas chromatography-mass spectrometry (GC-MS)-based metabolomics to characterize the physiological responses in haemolymph of New Zealand Greenshell™ mussels (Perna canaliculus) injected with Vibrio sp. DO1 (V...
April 2, 2018: Marine Biotechnology
https://www.readbyqxmd.com/read/29584640/greenshell%C3%A2-mussels-a-review-of-veterinary-trials-and-future-research-directions
#2
REVIEW
Charles T Eason, Serean L Adams, Jonathan Puddick, Donato Romanazzi, Matthew R Miller, Nick King, Sarah Johns, Elizabeth Forbes-Blom, Paul A Hessian, Lisa K Stamp, Michael A Packer
The therapeutic benefits of Greenshell™ mussel (GSM; Perna canaliculus ) preparations have been studied using in vitro test systems, animal models, and human clinical trials focusing mainly on anti-inflammatory and anti-arthritic effects. Activity is thought to be linked to key active ingredients that include omega-3 polyunsaturated fatty acids, a variety of carotenoids and other bioactive compounds. In this paper, we review the studies that have been undertaken in dogs, cats, and horses, and outline new research directions in shellfish breeding and high-value nutrition research programmes targeted at enhancing the efficacy of mussel and algal extracts...
March 27, 2018: Veterinary Sciences
https://www.readbyqxmd.com/read/29577102/a-case-with-corneal-perforation-due-to-bacterial-concretion-derived-from-lacrimal-canaliculitis
#3
Sho Ishikawa, Naoko Kato
Purpose: To report a case with corneal perforation, presumably due to ocular cicatricial pemphigoid (OCP) and bacterial concretion derived from lacrimal canaliculitis. Observations: A patient with OCP demonstrated adherence of concretion to the cornea of her right eye. She also demonstrated canaliculitis in this eye. We removed a whitish precipitate from the bottom of the corneal ulcer. When we flushed her lacrimal pathway, a marked amount of bacterial concretion and dense mucosa were refluxed from both puncta on the right side...
March 2018: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29563770/a-new-surgical-approach-for-punctal-occlusion-using-fibrous-tissue-from-under-the-lacrimal-caruncle
#4
Norihiko Yokoi, Aoi Komuro, Chie Sotozono, Shigeru Kinoshita
Purpose: Surgical punctal occlusion is indispensable for the treatment of severe dry eye in cases where punctal-plug insertion is not applicable due to an enlarged or deformed punctum. However, permanent punctal occlusion is difficult in some cases. In our aim to establish a more reliable punctal occlusion, we have devised a new surgical approach for punctal occlusion. Patients and methods: This study involved 20 puncta of 12 eyes of 12 patients (1 male and 11 females; mean age: 65...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29561477/repair-of-lower-canalicular-laceration-using-the-mini-monoka-stent-primary-and-revisional-repairs
#5
Yong-Ha Kim, Chi-Ho Yeo, Kyu-Jin Chung, Jun Ho Lee, Taegon Kim
BACKGROUND: We present our results of primary repair of lower canalicular injury using the Mini-Monoka stent and report our experience with revisional repair of canalicular blocks to treat epiphora following primary repair METHODS:: We performed primary repair in 169 canalicular laceration patients using Mini-Monoka. The primary repair was defined as the first operation proceeded within 48 hours after injury. Revisional repairs were performed in patients who underwent primary repair of canalicular laceration and subsequently complained of epiphora with canalicular block owing to peripheral scarring...
March 20, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29550995/first-report-of-toxoplasma-gondii-sporulated-oocysts-and-giardia-duodenalis-in-commercial-green-lipped-mussels-perna-canaliculus-in-new-zealand
#6
Alicia Coupe, Laryssa Howe, Elizabeth Burrows, Abigail Sine, Anthony Pita, Niluka Velathanthiri, Emilie Vallée, David Hayman, Karen Shapiro, Wendi D Roe
Pollution of marine ecosystems with the protozoan parasites Toxoplasma gondii, Cryptosporidium spp. and Giardia duodenalis can be studied using bivalve shellfish as biosentinels. Although evidence suggests that these parasites are present in New Zealand coastal waters, the extent of protozoal pollution has not been investigated. This study used optimised molecular methods to detect the presence of Cryptosporidium spp., G. duodenalis and T. gondii in commercially sourced green-lipped mussel (Perna canaliculus), an endemic species found throughout coastal New Zealand...
March 17, 2018: Parasitology Research
https://www.readbyqxmd.com/read/29373404/idiopathic-canalicular-inflammatory-disease-new-disease-description-of-clinical-patterns-investigations-management-and-outcomes
#7
Mohammad Javed Ali
PURPOSE: The objective of this perspective is to present a separate disease description of "idiopathic canalicular inflammatory disease" and outline the diagnostic criteria and early experiences with its investigations and management. METHODS: Retrospective case series of 44 canaliculi of 22 eyes of 11 patients presenting at a tertiary care Dacryology service over a period of 2 years with typical clinical patterns of inflammatory canaliculitis and its outcomes were studied...
January 25, 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29272988/the-influence-of-the-subarcuate-artery-in-the-superior-semicircular-canal-dehiscence-and-its-frequency-on-stillbirths-illustrative-cases-and-systematic-review
#8
Gabriela Pereira Bom Braga, Jack H Noble, Eloisa Maria Mello Santiago Gebrim, Robert F Labadie, Ricardo Ferreira Bento
Literature describes that on the 25th gestational week the labyrinth is fully formed and with adult size. However, recent studies have shown that the cranial and labyrinth development continues until 3 years of age. OBJECTIVES: To demonstrate through tomographic study the frequency of semicircular canal dehiscence on nine specimens of stillbirths between 32 and 40 weeks and, through literature review, present another possible etiology for its cause. METHODS: Tomographic study of the temporal bone of 9 specimens of stillbirths between 32 and 40 weeks...
December 22, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29210641/dynamic-localization-of-hepatocellular-transporters-role-in-biliary-excretion-and-impairment-in-cholestasis
#9
Marcelo Gabriel Roma, Ismael R Barosso, Gisel S Miszczuk, Fernando A Crocenzi, Enrique J Sanchez Pozzi
Bile flow generation is driven by the vectorial transfer of osmotically active compounds from sinusoidal blood into a confined space, the bile canaliculus. Hence, localization of hepatocellular transporters relevant to bile formation is crucial for bile secretion. Hepatocellular transporters are localized either in the plasma membrane or in recycling endosomes, from where they can be relocated to the plasma membrane on demand, or endocytosed when the demand decreases. The balance between endocytic internalization/exocytic targeting to/from this recycling compartment is therefore the main determinant of the hepatic capability to generate bile, and to dispose endo- and xenobiotics...
December 5, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/29205455/the-middle-and-inner-ears-of-the-palaeogene-golden-mole-namachloris-a-comparison-with-extant-species
#10
Matthew J Mason, Nigel C Bennett, Martin Pickford
Many living species of golden moles (Chrysochloridae) have greatly enlarged middle ear ossicles, believed to be used in the detection of ground vibrations through inertial bone conduction. Other unusual features of chrysochlorids include internally coupled middle ear cavities and the loss of the tensor tympani muscle. Our understanding of the evolutionary history of these characteristics has been limited by the paucity of fossil evidence. In this article, we describe for the first time the exquisitely preserved middle and inner ears of Namachloris arenatans from the Palaeogene of Namibia, visualised using computed tomography, as well as ossicles attributed to this species...
March 2018: Journal of Morphology
https://www.readbyqxmd.com/read/29132968/canaliculitis-due-to-gemella-haemolysans-in-a-single-isolate
#11
J L Romero-Trevejo, J Somavilla-Lupiáñez
CASE REPORT: An 84 year-old woman was referred for evaluation of a painless swelling with small purulent discharge in her left upper canaliculus, and an associated epiphora of one-month duration. The patient was diagnosed with acute primary canaliculitis. She was treated with topical and oral antibiotics, as well as topical corticoids for three months, with little response. Surgical treatment with left upper canaliculotomy and curettage was then performed, and Gemella haemolysans was identified from the curetted material...
November 10, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/28990978/bicanalicular-canaliculops-and-its-dacryoendoscopic-findings
#12
Alice Venyir Ramyil, Shweta Gupta, Mohammad Javed Ali, Milind N Naik
Canaliculops is a noninflammatory ectasia of the canaliculus and so far only 7 histopathologically confirmed cases have been reported worldwide. The authors present a middle aged female with right-sided bicanalicular cystic swellings associated with punctal agenesis. Ultrasound biomicroscopy showed a cystic dilatation of the canaliculus and dacryoendoscopy showed a cavity lined by whitish canalicular mucosa, thrown into numerous irregular folds with a blind medial end. Histopathological examination confirmed the diagnosis of canaliculops...
September 27, 2017: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28985810/effectiveness-of-indocyanine-green-gel-in-the-identification-and-complete-removal-of-the-medial-wall-of-the-lacrimal-sac-during-endoscopic-endonasal-dacryocystorhinostomy
#13
Jinhwan Park, Jongsuk Lee, Hwa Lee, Sehyun Baek
OBJECTIVE: We investigated the effect of using indocyanine green (ICG) gel, a mixture of ICG and Viscoat, on complete removal of the medial wall of the lacrimal sac as well as the success rate of endoscopic endonasal dacryocystorhinostomy (DCR) for primary acquired nasolacrimal duct obstruction. METHODS: Consecutive cases of endoscopic endonasal DCR between January and December 2010 were included in a retrospective, comparative manner. A total of 91 patients with primary acquired nasolacrimal duct obstruction were enrolled...
October 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/28979842/msp22-8-is-a-protease-inhibitor-like-protein-involved-in-shell-mineralization-in-the-edible-mussel-mytilus-galloprovincialis
#14
Juan Calvo-Iglesias, Daniel Pérez-Estévez, África González-Fernández
The mussel shell protein 22.8 (MSP22.8) is recognized by a monoclonal antibody (M22.8) directed against larvae of the mussel Mytilus galloprovincialis . After being secreted by cells of the mantle-edge epithelium into the extrapallial (EP) space (the gap between the mantle and the shell), the protein is detected in the extrapallial fluid (EPF) and EP hemocytes and finally becomes part of the shell matrix framework in adult specimens of M. galloprovincialis . In the work described here, we show how MSP22.8 is detected in EPF samples from different species of mussels ( M...
October 2017: FEBS Open Bio
https://www.readbyqxmd.com/read/28872387/correction-to-nesaratnam-emeriewen-smith-david-wawrzynski-sharma-and-saleh-scaling-the-punctum-and-canaliculus-in-patients-undergoing-punctoplasty-surgery-a-prospective-cohort-study
#15
https://www.readbyqxmd.com/read/28860909/anatomical-and-functional-outcomes-of-canalicular-laceration-repair-with-self-retaining-mini-monoka-stent
#16
Md Shahid Alam, Neha Shrirao Mehta, Bipasha Mukherjee
AIM: To evaluate the anatomical and functional outcomes of canalicular laceration repair with self retaining monocanalicular intubation system (Mini-MONOKA). MATERIALS AND METHODS: The data of 29 patients undergoing canalicular laceration repair from 2010 to 2014 were retrospectively analyzed. Operative details and complications were noted. The stent was removed earliest at 3 months. Anatomical and functional success was defined by a patent syringing and the absence of epiphora respectively...
July 2017: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/28837389/basaloid-adenocarcinoma-of-the-lacrimal-sac-a-rare-entity-and-approach-to-management
#17
Alison B Huggins, Mary A Stefanyszyn, Gurston Nyquist, Michael P Rabinowitz
Presented is a rare case of basaloid adenocarcinoma of the lacrimal sac. Low grade features of this malignancy permitted a conservative surgical approach to maximize functional and cosmetic outcomes. This is retrospective case description of a single 77-year-old-female patient who underwent a dacryocystorhinostomy with silicone tubes at an outside hospital for epiphora, but was referred to the Wills Eye Hospital Oculoplastics Department for a lacrimal sac biopsy showing low-grade carcinoma with basaloid features...
December 2017: Orbit
https://www.readbyqxmd.com/read/28830818/review-of-anti-inflammatory-immune-modulatory-and-wound-healing-properties-of-molluscs
#18
REVIEW
Tarek B Ahmad, Lei Liu, Michael Kotiw, Kirsten Benkendorff
ETHNOPHARMACOLOGICAL RELEVANCE: This review focuses on traditional and contemporary anti-inflammatory uses of mollusc-derived products summarising all the in vitro, in vivo and human clinical trials that have tested the anti-inflammatory activity of molluscan natural products. Inflammatory conditions, burns and wounds have been an ongoing concern for human health since the early era of civilisation. Many texts from ancient medicine have recorded the symptoms, signs and treatments for these conditions...
August 19, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28830491/a-randomized-double-blind-placebo-controlled-trial-to-investigate-the-effectiveness-and-safety-of-a-novel-green-lipped-mussel-extract-biolex%C3%A2-for-managing-pain-in-moderate-to-severe-osteoarthritis-of-the-hip-and-knee
#19
RANDOMIZED CONTROLLED TRIAL
Simon Stebbings, Andrew Gray, Anthony G Schneiders, Andrew Sansom
BACKGROUND: Extracts from perna canaliculus, the Green Lipped Mussel (GLM) are widely used as a complimentary therapy by patients with osteoarthritis (OA). The current study investigated the potential of a novel GLM formulation as a treatment for OA. A randomized double-blind placebo-controlled trial was undertaken to assess potential impacts on pain and quality of life following 12 weeks of treatment. METHODS: Eighty patients with moderate to severe OA of the hip or knee were randomized to receive either 600 mg of BioLex®-GLM daily or placebo for 12 weeks...
August 22, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28816979/a-new-method-for-locating-the-proximal-lacerated-bicanalicular-ends-in-chinese-preschoolers-and-long-term-outcomes-after-surgical-repair
#20
Ai Zhuang, Xiaoliang Jin, Yinwei Li, Xianqun Fan, Wodong Shi
This report is to explore the long-term outcomes of surgical repair of bicanalicular lacerations in Chinese preschool patients. In this report, 12 patients with bicanalicular lacerations were studied between September 2010 and September 2015. The distance from the punctum to the distal canalicular lacerated end was recorded before surgery to classify different types of trauma. All patients underwent surgical repair of the lacerated canaliculi by 1 surgeon within 48 hours after the trauma occurred. After treatment, the lesions were divided into 3 types according to the distance from the punctum to the distal lacerated canalicular end as follows: lateral, medial, and the central...
August 2017: Medicine (Baltimore)
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