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Verruca treatment

Binti Zain Rosnah, George Kallarakkal Thomas, Ramanathan Anand, Kim Jin, Tilakaratne Wm, Takata Takashi, Warnakulasuriya Saman, Kumar Hazarey Vinay, Rich Alison, Mohd Hussaini Haizal, Jalil Ajura
Verruco-papillary lesions (VPLs) of the oral cavity described in the literature involve a spectrum of conditions including squamous papilloma, verruca vulgaris, focal epithelial hyperplasia, condyloma, proliferative verrucous leukoplakia and verrucous carcinoma. A majority of the VPLs are slow growing, benign in nature and have a viral aetiology. Virus associated benign mucosal outgrowths are not too difficult to diagnose either clinically or by microscopy. Apart from virus-associated lesions, VPLs harboring malignant potential or behaviour such as verrucous carcinoma, proliferative verrucous leukoplakia, oral verrucous hyperplasia (OVH), oral papillary squamous cell carcinoma (PSCC) and oral conventional squamous cell carcinoma with papillary features (CSCC) need to be further clarified for better understanding of their predictable biologic behavior and appropriate treatment...
January 9, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
Ali Balevi, Pelin Üstüner, Mustafa Özdemir
BACKGROUND: Recalcitrant facial verruca plana (FVP) may persist for years and full remission is not always achieved with conventional therapies. The clinical success rates reported for different lasers are highly variable and only one study evaluated the Er:YAG laser for the treatment of FVP. OBJECTIVE: To determine whether Er:YAG is safe and effective for the treatment of recalcitrant FVP. METHODS: Forty-six patients with recalcitrant FVP were treated by Er:YAG at four-week intervals...
October 3, 2016: Journal of Dermatological Treatment
Lindsey Zubritsky, Ali Alikhan
Verruca vulgaris is a common dermatological disease with many treatment options including destructive modalities and more recently, immunotherapy. Intralesional injections of Candida antigen have been described as a safe and effective treatment with the most common adverse reactions including local reactions (burning, blistering, peeling), local erythema, and pain at the injection site. We describe the first reported case of lymphangitis after intralesional Candida antigen injection for verruca vulgaris in a healthy 18-year-old woman...
2016: Dermatology Online Journal
Samujjala Deb, P Ishwara Bhat, Naveen Thomas
Viral warts are a common lesion found in patients who have undergone a renal transplant. The occurrence of verrucae also depends on the choice of immunosuppressant and posttransplant time interval. The presence of viral warts only on sun-exposed parts of the body is extremely uncommon and rarely reported. It might also influence the choice of treatment since these warts are often resistant to treatment.
July 2016: Indian Journal of Dermatology
Sarah Cockayne, Catherine Hewitt, Farina Hashmi, Kate Hicks, Michael Concannon, Caroline McIntosh, Kim Thomas, Jill Hall, Judith Watson, David Torgerson, Ian Watt
BACKGROUND: Trials using inadequate levels of blinding may report larger effect sizes than blinded studies. It has been suggested that blinded outcome assessment in open trials may in some cases be undertaken by assessments of photographs. The aim of this paper is to explore the effect of using different methods to assess the primary outcome in the EVerT (Effective Verruca Treatments) trial. It also aims to give an overview of the experiences of using digital photographs within the trial...
2016: Journal of Foot and Ankle Research
E L Maranda, V M Lim, A H Nguyen, K Nouri
Facial verruca plana, or flat warts, are benign skin papillomas caused by human papillomavirus infections. A large portion of cases are refractory to treatment and can cause psychosocial distress in patients. Laser and light modalities offer an alternative therapeutic approach that has not been extensively explored. We systematically reviewed PubMed for studies describing treatment of facial verruca plana using lasers, photodynamic therapy and infrared coagulation. Final inclusion and review of eighteen studies suggests laser and light therapies to have considerable potential in the treatment of this recalcitrant condition...
June 29, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
Mustafa Sagit, Ibrahim Hira, Halil Polat, Ebru Akay, Mehmet Yasar
Verruca vulgaris is a cutaneous disease manifested with a single or multiple, small painless lesions that may involve keratinized or nonkeratinized epithelium. It can be localized at skin or mucosa. It is a benign lesion; however, it is of importance to discriminate from verrucous carcinoma to plan treatment, especially in those with laryngeal localization. Total excision is adequate in the management of verruca vulgaris; thus, accurate differential diagnosis is essential to avoid unnecessary surgical interventions...
June 2016: Journal of Craniofacial Surgery
Tracey C Vlahovic, M Tariq Khan
Viral warts or verruca pedis (plantar warts) are common skin conditions seen in both children and adults. Human papilloma virus (HPV), a DNA virus, is responsible for plantar verrucae. It needs an epidermal abrasion and a transiently impaired immune system to inoculate a keratinocyte. These entities are a therapeutic conundrum for many practitioners. This article discusses HPV infiltration and its subtypes involved in plantar warts; the evaluation of patients with plantar warts; and subsequent treatment options, such as laser, Candida albicans immunotherapy, topical therapy such as phytotherapy, and surgical excision...
July 2016: Clinics in Podiatric Medicine and Surgery
Jannett Nguyen, Dorota Z Korta, Lance W Chapman, Kristen M Kelly
IMPORTANCE: Although cutaneous warts are common lesions, full remission is not always achieved with conventional therapies. Laser modalities including carbon dioxide (CO2), erbium:yttrium-aluminum-garnet (Er:YAG), pulsed dye (PDL), and Nd:YAG have been investigated as alternative treatments for warts. OBJECTIVE: To review the use and efficacy of lasers for treating nongenital cutaneous warts. EVIDENCE REVIEW: Published randomized clinical trials (RCTs), cohort studies, case series, and case reports involving laser treatment of nongenital warts were retrieved by searching PubMed with no date limits...
September 1, 2016: JAMA Dermatology
Ya-Li Yang, Junjun Sang, Ning-Xin Liao, Fang Wei, Wanqin Liao, Jiang-Han Chen
The facial flat wart (verruca plana) is one of the most common reasons for dermatology and primary care visits. Although there are many therapeutic modalities, no single therapy has been proven to be completely curative. Case reports and uncontrolled studies suggested that photodynamic therapy (PDT) with topical 5-aminolevulinic acid (ALA) can effectively treat recalcitrant facial flat warts. A total of 12 patients with recalcitrant facial flat warts were enrolled in the study. ALA gel (10 %) was applied topically to lesions and incubated for 3 h...
July 2016: Lasers in Medical Science
Yoshinari Nagakane, Hidesato Takezawa, Kanade Katsura, Yasumasa Yamamoto
A 60-year-old man was admitted to our hospital because of vertigo and repeated vomiting, which suddenly occurred 25 hours before admission. Neurologic examination revealed Wallenberg syndrome on the left side, and brain MRI showed acute infarcts in the left lateral medulla as well as in the left internal carotid artery (ICA) territory. MR angiography did not depict the left vertebral artery (VA) and the left ICA. Despite antithrombotic treatment, he developed bulbar palsy, and then, brain herniation due to infarct growth in the left middle cerebral artery territory...
2016: Rinshō Shinkeigaku, Clinical Neurology
Kai-yu Huang, Shuang Liang, Guang-yong Hu, Yang-yang Zou, Lu Lu, Jian-bin Zhang
Moxibustion is one of the major external therapies of traditional Chinese medicine (TCM) and exerts a definite favorable effect in the treatment of patients with different problems. In the present paper, the authors reviewed 38 papers about somatic thermal intervention therapy published in recent 15 years and analyzed its biological functions from local, distal, and whole body effects. The local effects include 1) improving cutaneous inflammatory illnesses as verruca, herpes simplex, Leishmania infection, cutaneous necrosis, wound disunion, and promoting percutaneous absorption of some medicines, swelling pain; 2) reliving sports fatigue and muscular injury, eliminating inflammation and pain reactions, probably by lowering local reactive oxygen species, superoxide dismutase,catalase, glutathione, etc...
December 2015: Zhen Ci Yan Jiu, Acupuncture Research
Autumn Bagwell, Abbey Loy, M Shawn McFarland, Amber Tessmer-Neubauer
OBJECTIVE: To describe a case in which persistent plantar warts resolved after a ten-day treatment course of oral acyclovir prescribed for herpes zoster. CASE SUMMARY: A 49 year-old Caucasian female with non-significant past medical history presented to the podiatry clinic for treatment of verrucae. Debridement was performed and monochloroacetic acid was applied to affected areas seven times over seven months. The patient was diagnosed and treated for herpes zoster with acyclovir for ten days...
February 2016: Journal of Drugs in Dermatology: JDD
Zhou Zhou, T Liu, Z Zhang
OBJECTIVES: Skin disease is one of the major components of health problems for soldiers either during war or peacetime. Despite increased numbers and scale of military missions, dermatological survey is limited. The aim of this study was to outline the dermatological profile in international peacekeepers in Lebanon and to explore the features of disease pattern. METHODS: The dermatological records of peacekeepers visiting a Chinese Level 2 hospital during a 7-year period were retrospectively assessed...
January 8, 2016: Journal of the Royal Army Medical Corps
Noriaki Nakai, Akifumi Ohshita, Junya Kuroda, Norito Katoh
No abstract text is available yet for this article.
2015: Acta Dermatovenerologica Croatica: ADC
Vikrant Saoji, Nitin R Lade, Rutuja Gadegone, Arun Bhat
BACKGROUND: Warts are known to clear spontaneously with the development of cell-mediated immunity (CMI) to the virus. Purified protein derivative (PPD) of tuberculin bacilli has been used as a non-specific stimulant of CMI to achieve this outcome. AIM: To study the effect of PPD in the treatment of warts. METHODS: Patients with difficult to treat warts were selected for immunotherapy. Each patient received 2.5 TU of PPD intralesionally in a few warts...
December 14, 2015: Indian Journal of Dermatology, Venereology and Leprology
Farina Hashmi, David Torgerson, Caroline Fairhurst, Sarah Cockayne, Kerry Bell, Michelle Cullen, Michael Harrison-Blount
INTRODUCTION: Verrucae are extremely common, and are experienced by most people at some time during their lives. Although most verrucae will spontaneously disappear without treatment, many patients seek treatment, often because they have persisted for many years, are unsightly or painful or prevent them from doing sports or other activities. There are many different treatments available; including the Falknor's needling procedure. To date, there has only been one small trial evaluating the clinical effectiveness of this treatment and no health economic analysis has been undertaken...
2015: BMJ Open
Ali Alikhan, John R Griffin, Catherine C Newman
Common warts (verruca vulgaris) are one of the most common problems encountered in dermatology and may present a difficult treatment dilemma, as no particular therapy has demonstrated complete efficacy. Intralesional injection of purified Candida antigen has produced impressive treatment results in small prospective and retrospective studies and is thought to produce its effect through stimulation of a cell-mediated immune response. We report a retrospective study of adult and pediatric patients treated with Candida antigen therapy in clinical practice...
August 2016: Journal of Dermatological Treatment
Kara Capriotti, Kevin P Stewart, Jesse S Pelletier, Joseph Capriotti
INTRODUCTION: Verruca vulgaris, also known as common warts, are benign skin growths caused by infection of the skin by human papillomavirus. Warts are common in both childhood and adulthood and are spread by direct contact or autoinoculation. Treatment options vary from locally destructive methods to immuno-modulatory therapy. Common warts are often resistant to treatment. Though many remedies exist, there is no consensus therapy backed by randomized-controlled clinical trials that are FDA approved for the treatment of verruca vulgaris...
November 3, 2015: Dermatology and Therapy
Lauren K Biesbroeck, Philip Fleckman
Nail disorders are a common presenting complaint for both the primary care physician and the dermatologist. Nail diagnoses are broad in scope and include infectious, inflammatory, and neoplastic conditions. Onychomycosis is an especially common nail condition, and treatment should always be preceded by appropriate fungal studies for confirmation of diagnosis. Inflammatory conditions of the nail unit can mimic onychomycosis, and a dermatologist can assist with diagnosis and treatment recommendations. Likewise, subungual tumors often require biopsy, and should be evaluated by a dermatologist who is experienced in nail evaluation and treatment...
November 2015: Medical Clinics of North America
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