keyword
https://read.qxmd.com/read/38525743/impact-of-antibiotics-used-for-acute-aspiration-bronchitis-on-the-prevention-of-pneumonia
#1
JOURNAL ARTICLE
Akihiko Goto, Kosaku Komiya, Kenji Umeki, Kazufumi Hiramatsu, Jun-Ichi Kadota
BACKGROUNDS: It remains unclear if antibiotics should be used for the treatment of acute aspiration bronchitis to prevent the development of pneumonia. This study aimed to assess the associations between the use of antibiotics and the development of pneumonia among patients with acute aspiration bronchitis. METHODS: We retrospectively reviewed consecutive patients with acute aspiration bronchitis aged ≥75 years. Acute aspiration bronchitis was defined as a condition with aspiration risk, high fever (body temperature, ≥37...
February 25, 2024: Geriatrics
https://read.qxmd.com/read/38525219/probiotic-supplementation-as-an-alternative-to-antibiotics-in-broiler-chickens
#2
JOURNAL ARTICLE
Grzegorz Tomczyk, Jowita Samanta Niczyporuk, Wojciech Kozdruń, Anna Sawicka-Durkalec, Łukasz Bocian, Marcin Barabasz, Marcin Michalski
INTRODUCTION: The broiler chicken digestive tract microbiome maintains the bird's immunity. Its composition has been shown to be important not only for the immune system but also for the gastrointestinal function and productivity of broiler chickens. If the microbiome is populated by supplementation with Lactobacillus, Pediococcus and Saccharomyces spp. - microorganisms with probiotic properties and alternatives to antibiotics - the immune system is stimulated. The use of probiotic supplements in the broiler production cycle can boost bird immunity and prevent adenovirus infection...
March 2024: Journal of Veterinary Research
https://read.qxmd.com/read/38510651/chinese-medicine-phragmites-communis-lu-gen-for-acute-respiratory-tract-infections-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#3
Min Fang, Ling-Yao Kong, Guang-He Ji, Feng-Lan Pu, You-Zhu Su, Yu-Fei Li, Michael Moore, Merlin Willcox, Jeanne Trill, Xiao-Yang Hu, Jian-Ping Liu
Background: Acute respiratory tract infections (ARTIs) are the most common cause of morbidity and mortality worldwide, with most people experiencing at least one episode per year. Current treatment options are mainly symptomatic therapy. Antivirals, antibiotics, and glucocorticoids are of limited benefit for most infections. Traditional Chinese medicine has shown potential benefits in the treatment of ARTIs. Objective: The objective of this study was to determine the efficacy, effectiveness, and safety of Phragmites communis Trin...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38496201/purpuric-type-drug-eruption-caused-by-azithromycin-a-case-report-and-literature-review
#4
Natsuko Saito-Sasaki, Yu Sawada
Azithromycin, an azolide antibiotic with structural and functional similarities to macrolides, possesses distinct features such as its effects persisting for seven days, an extended half-life by administering it once daily for three days, and strong antimicrobial activity. Notably, vomiting and diarrhea are recognized as the primary adverse events related to azithromycin. In this particular case, we present a unique case describing a purpuric-type drug eruption associated with azithromycin, which represents an uncommon cutaneous manifestation...
February 2024: Curēus
https://read.qxmd.com/read/38456194/diagnosis-and-treatment-of-pneumonia-in-urgent-care-clinics-opportunities-for-improving-care
#5
JOURNAL ARTICLE
James H Hart, Theadora Sakata, Jacqueline R Eve, Allison M Butler, Anthony Wallin, Chad Carman, Brenda Atwood, Rajendu Srivastava, Barbara E Jones, Edward A Stenehjem, Nathan C Dean
BACKGROUND: Community-acquired pneumonia is a well-studied condition; yet, in the urgent care setting, patient characteristics and adherence to guideline-recommended care are poorly described. Within Intermountain Health, a nonprofit integrated US health care system based in Utah, more patients present to urgent care clinics (UCCs) than emergency departments (EDs) for pneumonia care. METHODS: We performed a retrospective cohort study 1 January 2019 through 31 December 2020 in 28 UCCs within Utah...
March 2024: Open Forum Infectious Diseases
https://read.qxmd.com/read/38419286/effect-of-enrofloxacin-on-clinical-parameters-and-mucociliary-system-of-broilers-challenged-with-h9n2-avian-influenza-infectious-bronchitis-viruses
#6
JOURNAL ARTICLE
Mohammad Abbasnia, Najmeh Mosleh, Habibollah Dadras, Tahoora Shomali
BACKGROUND: Effect of antibacterials on mucociliary system and clinical outcome of chickens with mixed viral respiratory conditions is not properly addressed. OBJECTIVE: We evaluated enrofloxacin effects on clinical parameters and mucociliary system of broilers challenged with H9N2/IB viruses. METHODS: Broilers (105), at the age of 25 days, were randomly allocated into three groups: Group 1 (negative control), no treatment; Group 2 (positive control [PC]) challenged by intranasal and intraocular route...
March 2024: Veterinary Medicine and Science
https://read.qxmd.com/read/38272261/characteristics-of-pediatric-patients-claimed-with-acute-upper-respiratory-infection-during-otorhinolaryngology-consultations-a-descriptive-study-of-a-large-japanese-medical-claims-database
#7
JOURNAL ARTICLE
Saki Ito, Yuichi Muraki, Ryo Inose, Kanako Mizuno, Ryota Goto, Makiko Kiyosuke, Yoshitsugu Iinuma, Tetsuya Yagi, Hiroki Ohge
This study aimed to clarify other diseases claimed simultaneously with acute upper respiratory infection (URI), antibiotic prescriptions, and examinations associated with infectious diseases in pediatric patients with acute URI insurance claims at otorhinolaryngology outpatient visits. Pediatric patients who visited an otolaryngology department between 2019 and 2021 and were definitively diagnosed with URI were selected using a large Japanese medical claims database. Patient backgrounds, antibiotic use, and examinations were descriptively evaluated...
January 23, 2024: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://read.qxmd.com/read/38252922/early-career-general-practitioners-antibiotic-prescribing-for-acute-infections-a-systematic-review
#8
JOURNAL ARTICLE
Emma J Baillie, Greg Merlo, Mieke L Van Driel, Parker J Magin, Lisa Hall
BACKGROUND: Antimicrobial resistance is a worldwide threat, exacerbated by inappropriate prescribing. Most antibiotic prescribing occurs in primary care. Early-career GPs are important for the future of antibiotic prescribing and curbing antimicrobial resistance. OBJECTIVES: To determine antibiotic prescribing patterns by early-career GPs for common acute infections. METHODS: A systematic literature search was conducted using PubMed, Embase and Scopus...
January 22, 2024: Journal of Antimicrobial Chemotherapy
https://read.qxmd.com/read/38200763/precision-glycan-supplementation-improves-gut-microbiota-diversity-performance-and-disease-outbreak-resistance-in-broiler-chickens
#9
JOURNAL ARTICLE
Edina Lobo, Yadav S Bajagai, Advait Kayal, Santiago Ramirez, Anja Nikolić, Rolando Valientes, Dragana Stanley
The poultry industry contributes significantly to the global meat industry but faces many production challenges like high-density housing, welfare issues, and pathogenic infections. While antibiotics have commonly been used to treat many of these issues, they are being removed from poultry production globally due to increased microbial resistance. Precision glycans offer a viable alternative to antibiotics by modulating microbial metabolic pathways. In this study, we investigated the effects of precision glycan supplementation on productivity and gut microbiota in broilers...
December 21, 2023: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38193298/perspectives-of-primary-care-physicians-on-academic-detailing-for-antimicrobial-stewardship-feasibility-and-impact-assessment
#10
JOURNAL ARTICLE
Darija Kuruc Poje, Maja Kuharić, Ana Posavec Andrić, Vesna Mađarić, Janeš Vlatka Poje, Marina Payerl-Pal, Arjana Tambić Andrašević, Juraj Mark Poje, Vesna Bačić Vrca, Srećko Marušić
OBJECTIVE: To understand primary care physicians' perspectives on academic detailing from an antimicrobial stewardship team to combat antibiotic overuse for upper respiratory infections and bronchitis in the COVID-19 era, which will help prevent avoidable outpatient visits. METHODS: In this prospective study, 14 female Croatian physicians completed standardized qualitative interviews using a semi-structured guide. The data were analyzed using inductive methodology based on reflexive thematic analysis...
January 2024: Journal of International Medical Research
https://read.qxmd.com/read/38151632/compound-isolation-through-bioassay-guided-fractionation-of-tectona-grandis-leaf-extract-against-vibrio-pathogens-in-shrimp
#11
JOURNAL ARTICLE
Alokesh Kumar Ghosh, Sujogya Kumar Panda, Haibo Hu, Liliane Schoofs, Walter Luyten
Tectona grandis Linn, commonly known as teak, is traditionally used to treat a range of diseases, including the common cold, headaches, bronchitis, scabies, diabetes, inflammation, and others. The present study was conducted with the purpose of isolating and identifying the active compounds in T. grandis leaf against a panel of Vibrio spp., which may induce vibriosis in shrimp, using bioassay-guided purification. The antimicrobial activity was assessed using the microdilution method, followed by the brine shrimp lethality assay to determine toxicity...
December 27, 2023: International Microbiology: the Official Journal of the Spanish Society for Microbiology
https://read.qxmd.com/read/38089462/improving-antibiotic-prescribing-quality-in-out-of-hours-primary-care-a-mixed-methods-study-using-participatory-action-research
#12
JOURNAL ARTICLE
Annelies Colliers, Samuel Coenen, Stefan Teughels, Yentry Boogaerts, Olivia Vandeput, Anouk Tans, Helene Vermeulen, Roy Remmen, Hilde Philips, Sibyl Anthierens
BACKGROUND: During out-of-hours (OOH) primary care, GPs overprescribe antibiotics for respiratory tract infections (RTIs). Many interventions have been shown to improve antibiotic prescribing quality, but their implementation in practice remains difficult. Participatory action research (PAR) aims to explore, implement and evaluate change in practice with an active involvement of local stakeholders, while generating knowledge through experience. OBJECTIVES: To evaluate whether PAR improves antibiotic prescribing quality for RTIs during OOH primary care and simultaneously identify the pivotal lessons learned...
December 2023: JAC-antimicrobial resistance
https://read.qxmd.com/read/38072176/incomplete-and-possibly-selective-recording-of-signs-symptoms-and-measurements-in-free-text-fields-of-primary-care-electronic-health-records-of-adults-with-lower-respiratory-tract-infections
#13
JOURNAL ARTICLE
M H Merijn Rijk, T N Tamara Platteel, A M M Marissa Mulder, G J Geert-Jan Geersing, F H Frans Rutten, M Maarten van Smeden, R P Roderick Venekamp, A M Tuur Leeuwenberg
OBJECTIVE: To assess the completeness of recording of relevant signs, symptoms, and measurements in Dutch free text fields of primary care electronic health records (EHR) of adults with lower respiratory tract infections (LRTI). STUDY DESIGN AND SETTING: Retrospective cohort study embedded in a prediction modelling project using routine health care data of the Julius General Practitioners' Network of adult patients with LRTIs. Free text fields of 1,000 primary care consultations of LRTI episodes between 2016-2019 were manually annotated to retrieve data on the recording of sixteen relevant signs, symptoms, and measurements...
December 8, 2023: Journal of Clinical Epidemiology
https://read.qxmd.com/read/38066373/successful-use-of-phage-and-antibiotics-therapy-for-the-eradication-of-two-bacterial-pathogens-from-the-respiratory-tract-of-an-infant
#14
JOURNAL ARTICLE
Vera V Morozova, Yulia N Kozlova, Nina V Tikunova
Phage therapy can be a useful approach in a number of clinical cases associated with multidrug-resistant (MDR) bacterial infections. In this study, we describe a successful consecutive phage and antibiotic application to cure a 3-month-old girl suffering from severe bronchitis after tracheostomy. Bronchitis was associated with two bacterial agents, MDR Pseudomonas aeruginosa and a rare opportunistic pathogen Dolosigranulum pigrum. The phage cocktail "Pyobacteriophage" containing at least two different phages against isolated MDR P...
2024: Methods in Molecular Biology
https://read.qxmd.com/read/38058504/do-family-medicine-residents-optimally-prescribe-antibiotics-for-common-infectious-conditions-seen-in-a-primary-care-setting
#15
JOURNAL ARTICLE
Bernard Ho, Sahana Kukan, Warren McIsaac
BACKGROUND: Antimicrobial resistance is a worldwide phenomenon that leads to a significant number of unnecessary deaths and costly hospital admissions. More than 90% of antibiotic use happens in the community and of this, family physicians account for two-thirds of these prescriptions. Our study aims to determine whether family medicine residents are optimally trained in antibiotic prescribing for common infectious conditions seen in a primary care setting. METHODS: This study is a secondary analysis of a prior study of antimicrobial stewardship in two urban primary care clinics in central Toronto, Ontario...
November 2023: Journal of the Association of Medical Microbiology and Infectious Disease Canada, Journal officiel de l’Association pour la microbiologie médicale et l’infectiologie Canada
https://read.qxmd.com/read/38035342/high-oral-carriage-of-multidrug-resistant-gram-negative-bacilli-in-adolescents-the-sopkard-junior-study
#16
JOURNAL ARTICLE
Marta Katkowska, Katarzyna Garbacz, Ewa Kwapisz, Klaudia Suligowska, Aida Kusiak, Dominika Cichońska, Dariusz Świetlik
INTRODUCTION: The colonization of the oral cavity by potentially pathogenic antimicrobial-resistant bacteria in adolescents and its consequences is very poorly understood. The present study focused on the occurrence of oral colonization by Gram-negative bacilli (GNB) and their multidrug resistance, including the production of extended-spectrum β-lactamases (ESBLs) and carbapenemases, among healthy adolescents and risk factors associated with GNB colonization. MATERIALS AND METHODS: This study was conducted as part of "A program for the early detection of risk factors for lifestyle diseases SOPKARD-Junior" (SOPKARD-Junior)...
2023: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38034220/can-antibiotic-stewardship-be-achieved-by-utilizing-the-stewardship-through-educating-patients-s-t-e-p-process
#17
JOURNAL ARTICLE
Kathy L Havlicek, Ahmed Muhsin
BACKGROUND: Despite research and efforts to mitigate bacterial resistance, antibiotic overprescribing continues to occur, often due to real or perceived expectations of patients.  Objective: The purpose of this study was to determine: (1) if there's an association between the provider's patient education efforts and the patient's satisfaction, and (2) the research participant's subsequent behavior concerning antibiotic prescriptions, by utilizing the Stewardship Through Educating Patients (S...
October 2023: Curēus
https://read.qxmd.com/read/37986387/fatal-bacteremia-caused-by-staphylococcus-argenteus-a-case-report
#18
JOURNAL ARTICLE
Yu Zhan, Ruizhi Tang, Yingmiao Zhang, Xun Li, Yue Fan, Jing Wang, Hui Wang, Zhongxin Lu
RATIONALE: Staphylococcus argenteus (S argenteus) is a novel and emerging species that is part of the Staphylococcus aureus (S aureus) complex. Fatal cases of bloodstream infection caused by S argenteus are rarely reported and should be considered in medical practice. PATIENT CONCERNS: A 44-year-old male was admitted to our hospital with reduced appetite, high fever and unconsciousness. Laboratory tests indicated infection, muscle damage, and alkalosis in the patient...
November 17, 2023: Medicine (Baltimore)
https://read.qxmd.com/read/37887192/changes-in-the-prescription-of-antibiotics-and-phytopharmaceuticals-in-children-treated-for-acute-upper-and-lower-respiratory-tract-infections-in-pediatric-practices-in-germany-in-2013-2018-and-2022
#19
JOURNAL ARTICLE
Karel Kostev, Louisa van den Boom, Christian Tanislav, Louis Jacob
Background : Little is known about the recent trends in antibiotic and phytopharmaceutical prescribing for acute upper (URIs) and lower respiratory tract infections (LRIs) in children and adolescents. Therefore, this study investigated changes in the prescription of antibiotics and phytopharmaceuticals in children diagnosed with acute URIs and LRIs in pediatric practices in Germany in 2013, 2018, and 2022. Methods : The present retrospective study included children aged 2-12 years diagnosed with acute URIs or LRIs in one of 180 pediatric practices in 2013, 2018, and 2022...
September 28, 2023: Antibiotics
https://read.qxmd.com/read/37870542/choosing-wisely-interventions-to-reduce-antibiotic-overuse-in-the-safety-net
#20
JOURNAL ARTICLE
Richard K Leuchter, Catherine A Sarkisian, Rebecca Trotzky-Sirr, Eric K Wei, Carmen A Carrillo, Sitaram Vangala, Charles Coffey, Brad Spellberg, Oleg Melamed, Arthur C Jeng, John N Mafi
OBJECTIVES: Physician pay-for-performance (P4P) programs frequently target inappropriate antibiotics. Yet little is known about P4P programs' effects on antibiotic prescribing among safety-net populations at risk for unintended harms from reducing care. We evaluated effects of P4P-motivated interventions to reduce antibiotic prescriptions for safety-net patients with acute respiratory tract infections (ARTIs). STUDY DESIGN: Interrupted time series. METHODS: A nonrandomized intervention (5/28/2015-2/1/2018) was conducted at 2 large academic safety-net hospitals: Los Angeles County+University of Southern California (LAC+USC) and Olive View-UCLA (OV-UCLA)...
October 2023: American Journal of Managed Care
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