Yu-Ting Wu, Guo-Yong Zhang, Lei Li, Bin Liu, Ru-Yu Wang, Rong-Qiang Song, Yue Hua, Yi-Ming Bi, Xin Han, Feng Zhang, Dong Wang, Ling-Peng Xie, Ying-Chun Zhou
ETHNOPHARMACOLOGICAL RELEVANCE: Ferroptosis, a recently identified non-apoptotic form of cell death reliant on iron, is distinguished by an escalation in lipid reactive oxygen species (ROS) that are iron-dependent. This phenomenon has a strong correlation with irregularities in iron metabolism and lipid peroxidation. Salvia miltiorrhiza Bunge (DS), a medicinal herb frequently utilized in China, is highly esteemed for its therapeutic effectiveness in enhancing blood circulation and ameliorating blood stasis, particularly during the treatment of cardiovascular diseases (CVDs)...
April 17, 2024: Journal of Ethnopharmacology