keyword
https://read.qxmd.com/read/38175574/-influenza-associated-acute-necrotizing-encephalitis-unknown-makes-undertreated
#21
JOURNAL ARTICLE
Roel L N Huijsmans, Annemarije Braber, Christiaan Fokke, Jerome R Lo Ten Foe, Marnix Kuindersma
BACKGROUND: Influenza-associated acute necrotizing encephalitis (ANE) is a very rare, but severe complication from influenza infection. CASE DESCRIPTION: We present a 48 year old male who presented with fever, malaise, confusion and altered mental status (E4M5V2) and influenza A infection. He quickly develops convulsions after which he is intubated and admitted to the Intensive Care Unit following which he remains comatose (E1M1V1). The diagnosis of influenza associated acute necrotizing encephalitis is made based on his neurological symptoms, generalized slowing on electro-encephalogram, classic bilateral findings on MRI in the thalamus and basal ganglia and proven influenza infection in the cerebrospinal fluid...
November 23, 2023: Nederlands Tijdschrift Voor Geneeskunde
https://read.qxmd.com/read/38160579/coexistence-of-temporal-lobe-epilepsy-and-idiopathic-generalized-epilepsy
#22
JOURNAL ARTICLE
Ali A Asadi-Pooya, Mahdi Malekpour, Ehsan Taherifard, Arashk Mallahzadeh, Mohsen Farjoud Kouhanjani
OBJECTIVE: We investigated the frequency of coexistence of temporal lobe epilepsy (TLE) and idiopathic generalized epilepsy (IGE) in a retrospective database study. We also explored the underlying pathomechanisms of the coexistence of TLE and IGE based on the available information, using bioinformatics tools. METHODS: The first phase of the investigation was a retrospective study. All patients with an electro-clinical diagnosis of epilepsy were studied at the outpatient epilepsy clinic at Shiraz University of Medical Sciences, Shiraz, Iran, from 2008 until 2023...
December 30, 2023: Epilepsy & Behavior: E&B
https://read.qxmd.com/read/38067765/optical-sensors-for-bacterial-detection
#23
REVIEW
Olga I Guliy, Olga A Karavaeva, Andrey V Smirnov, Sergei A Eremin, Viktor D Bunin
Analytical devices for bacterial detection are an integral part of modern laboratory medicine, as they permit the early diagnosis of diseases and their timely treatment. Therefore, special attention is directed to the development of and improvements in monitoring and diagnostic methods, including biosensor-based ones. A promising direction in the development of bacterial detection methods is optical sensor systems based on colorimetric and fluorescence techniques, the surface plasmon resonance, and the measurement of orientational effects...
November 24, 2023: Sensors
https://read.qxmd.com/read/38050376/interfacial-electromigration-for-analysis-of-biofluid-lipids-in-small-volumes
#24
JOURNAL ARTICLE
Madison E Edwards, Dallas P Freitas, Erin A Hirtzel, Nicholas White, Hongying Wang, Laurie A Davidson, Robert S Chapkin, Yuxiang Sun, Xin Yan
Lipids are important biomarkers within the field of disease diagnostics and can serve as indicators of disease progression and predictors of treatment effectiveness. Although lipids can provide important insight into how diseases initiate and progress, mass spectrometric methods for lipid characterization and profiling are limited due to lipid structural diversity, particularly the presence of various lipid isomers. Moreover, the difficulty of handling small-volume samples exacerbates the intricacies of biological analyses...
December 4, 2023: Analytical Chemistry
https://read.qxmd.com/read/38002486/neuropsychological-functioning-in-bilateral-versus-unilateral-temporal-lobe-epilepsy
#25
JOURNAL ARTICLE
Martina Baggio, Alberto Danieli, Cristiano Crescentini, Gian Marco Duma, Martina Da Rold, Sara Baldini, Eric Pascoli, Lisa Antoniazzi, Alec Vestri, Franco Fabbro, Paolo Bonanni
Although relatively specific anatomo-electro-clinical features of temporal lobe epilepsy (TLE) with bilateral ictal involvement (bitemporal epilepsy-BTLE) have been described, differentiating between BTLE and unilateral TLE (UTLE) remains challenging. Surgery is often the treatment of choice for drug-resistant UTLE, whereas its use is more controversial in BTLE. It is currently unclear whether neuropsychological assessment can contribute to the differential diagnosis. We retrospectively reviewed the neuropsychological evaluation of 46 consecutive patients with refractory TLE...
October 29, 2023: Brain Sciences
https://read.qxmd.com/read/37993482/lemon-extract-supported-green-synthesis-of-bimetallic-cuo-ag-nanoporous-materials-for-sensitive-detection-of-vitamin-d3
#26
JOURNAL ARTICLE
Gowhar A Naikoo, Fay M Almashali, Fatima A S Habis, Mustri Bano, Jahangir Ahmad Rather, Israr U Hassan, Rayees Ahmad Sheikh, Palanisamy Kannan, Iman M Alfagih, Murtaza M Tambuwala
In modern era, deficiency of Vitamin D3 is predominantly due to limited exposure to sunlight and UV radiation resulting from indoor lifestyles. Several studies have revealed that vitamin D deficiency can lead to chronic vascular inflammation, diabetes mellitus, hypertension, congestive left ventricular hypertrophy, and heart failure. This study introduces a green synthesis of novel bimetallic nanoporous composite, CuO/Ag using lemon extract. The synthesized nanoporous material, CuO/Ag@lemon extract was characterized using several analytical techniques, including X-ray diffraction (XRD), transmission electron microscopy (TEM), scanning electron microscopy (SEM), and energy-dispersive X-ray spectroscopy (EDX)...
November 22, 2023: Scientific Reports
https://read.qxmd.com/read/37967099/intelligent-diagnosis-and-prediction-of-turbine-digital-electro-hydraulic-control-system-faults-design-and-experimentation
#27
JOURNAL ARTICLE
Ling Zhong, Qing Li
A physical modeling approach was adopted to build a Digital Electro-Hydraulic Control (DEH) system simulation model and the fault models using the SIMULINK tool. This research combined the advantages of the gray system and neural network to build a multi-parameter gray error neural network fault prediction model for the first time. Furthermore, an embedded platform for intelligent fault diagnosis and prediction was developed using an Application Specific Integrated Circuit chip. The results show that the simulation model of the DEH system has good performance...
2023: PloS One
https://read.qxmd.com/read/37960557/endoluminal-procedures-and-devices-for-esophageal-tract-investigation-a-critical-review
#28
REVIEW
Giorgia Spreafico, Marcello Chiurazzi, Davide Bagnoli, Sergio Emiliani, Nicola de Bortoli, Gastone Ciuti
Diseases of the esophageal tract represent a heterogeneous class of pathological conditions for which diagnostic paradigms continue to emerge. In the last few decades, innovative diagnostic devices have been developed, and several attempts have been made to advance and standardize diagnostic algorithms to be compliant with medical procedures. To the best of our knowledge, a comprehensive review of the procedures and available technologies to investigate the esophageal tract was missing in the literature. Therefore, the proposed review aims to provide a comprehensive analysis of available endoluminal technologies and procedures to investigate esophagus health conditions...
October 31, 2023: Sensors
https://read.qxmd.com/read/37957665/label-free-multimodal-electro-thermo-mechanical-etm-phenotyping-as-a-novel-biomarker-to-differentiate-between-normal-benign-and-cancerous-breast-biopsy-tissues
#29
JOURNAL ARTICLE
Anil Vishnu G K, Gayatri Gogoi, Midhun C Kachappilly, Annapoorni Rangarajan, Hardik J Pandya
BACKGROUND: Technologies for quick and label-free diagnosis of malignancies from breast tissues have the potential to be a significant adjunct to routine diagnostics. The biophysical phenotypes of breast tissues, such as its electrical, thermal, and mechanical properties (ETM), have the potential to serve as novel markers to differentiate between normal, benign, and malignant tissue. RESULTS: We report a system-of-biochips (SoB) integrated into a semi-automated mechatronic system that can characterize breast biopsy tissues using electro-thermo-mechanical sensing...
November 13, 2023: Journal of Biological Engineering
https://read.qxmd.com/read/37875328/enhancing-classical-swine-fever-virus-identification-the-advantages-of-field-lamp-testing
#30
JOURNAL ARTICLE
D H Tran, H T Tran, Btt Vo, T T Than, V T Nguyen, V P Le, Htt Phung
Classical swine fever virus (CSFV) identification has witnessed significant advancements with the development of rapid reverse-transcription loop-mediated isothermal amplification (RT-LAMP) assays. However, conventional RT-LAMP assays for CSFV diagnosis are hindered by a laborious RNA extraction step. Moreover, the need for thermal incubators and expensive micropipettes has limited their application in field settings. Addressing these challenges, our study presents a groundbreaking solution-an electro-free and point-of-care (POC) tool known as the field-LAMP assay-for the rapid clinical detection of CSFV...
October 24, 2023: Australian Veterinary Journal
https://read.qxmd.com/read/37835729/sperm-quality-assessment-in-stallions-how-to-choose-relevant-assays-to-answer-clinical-questions
#31
REVIEW
Sophie Egyptien, Stéfan Deleuze, Joy Ledeck, Jérôme Ponthier
Stallion sperm analysis is indicated for infertility diagnosis, pre-sale expertise, production of fresh or frozen doses, and frozen straw quality control. Various collection methods are described, and numerous assays can be performed on semen. Determining an approach for each of these cases is challenging. This review aims to discuss how to obtain relevant clinical results, answering stallion owners' concerns. Semen can be collected with an artificial vagina on a phantom or a mare, by electro-ejaculation under anesthesia, or after pharmacological induction...
October 6, 2023: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/37790161/cervical-pre-cancer-screening-by-visual-inspection-of-the-cervix-after-application-of-acetic-acid-in-rural-burkina-faso-evaluation-of-women-s-knowledge-screening-practice-habits-acceptability-and-prevalence-of-risk-factors-and-lesions-in-bouss%C3%A3-health-district
#32
JOURNAL ARTICLE
Souleymane Tassembedo, Christian Henrik Winter, Isidore Tiandiogo Traore, Adama Ouattara, Mamadou Sawadogo, Nicolas Meda
INTRODUCTION: cervical cancer is a major public health problem among women in sub-Saharan Africa. The disease can be controlled through early diagnosis through simple cost-effective methods such as visual inspection of the cervix after application of acetic acid or lugol´s iodine. However, screening for cervical cancer is still underused particularly in rural areas of Burkina Faso. The objective was to estimate the prevalence of cervical pre-cancer cancer in rural health district of Boussé, Burkina Faso...
2023: Pan African Medical Journal
https://read.qxmd.com/read/37780717/acute-motor-sensory-axonal-polyneuropathy-variant-of-guillain-barr%C3%A3-syndrome-with-a-thalamic-lesion-and-covid-19-a-case-report-and-discussion-on-mechanism
#33
Na Geng, Pengfei Wang, Yong Zhang
BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily affects the respiratory system. During the global coronavirus disease (COVID-19) pandemic, COVID-19-associated neurological diseases have been increasingly reported, including peripheral nervous system diseases, such as Guillain-Barré syndrome (GBS). Acute motor-sensory axonal polyneuropathy (AMSAN), is a GBS variant associated with COVID-19. To date, there are no reports of GBS cases with thalamic injury and dynamic evolution with fluctuating GBS symptoms...
2023: Frontiers in Neurology
https://read.qxmd.com/read/37777915/utility-of-median-to-ulnar-sensory-comparative-nerve-conduction-study-to-increase-diagnostic-accuracy-in-mild-carpal-tunnel-syndrome
#34
JOURNAL ARTICLE
R A Chowdhury, M M Rahman, M N Islam, S Roy, M H Rahman, M H Hasan, M W Rahman, I Alam
Electro-physiological diagnosis of mild Carpal Tunnel Syndrome (CTS) based on traditional median motor and sensory studies are often inconclusive. Therefore, we wanted to investigate the utility of Median-to-Ulnar Sensory Conduction studies in diagnosis of mild CTS. Data from Nerve conduction study (NCS) of 82 cases with symptoms suggestive of CTS from September 2017 to October 2020 attending electrophysiology department of Mount Adora Hospital, Sylhet, Bangladesh was selected for study. About 54(66.0%) out of 82 symptomatic patients were diagnosed as CTS by the conventional method, and 28(34...
October 2023: Mymensingh Medical Journal: MMJ
https://read.qxmd.com/read/37776308/post-hypoxic-status-epilepticus-a-distinct-subtype-of-status-epilepticus-with-poor-prognosis
#35
JOURNAL ARTICLE
Kateriine Orav, Pilar Bosque Varela, Tanja Prüwasser, Lukas Machegger, Markus Leitinger, Eugen Trinka, Giorgi Kuchukhidze
OBJECTIVE: To evaluate the clinical outcome of patients with possible and definitive post-hypoxic status epilepticus (SE) and to describe the SE types in patients with definitive post-hypoxic SE. METHODS: Patients with definitive or possible SE resulting from hypoxic brain injury after cardiac arrest (CA) were prospectively recruited. Intermittent EEG was used for the diagnosis of SE according to clinical practice. Two raters blinded to outcome analyzed EEGs retrospectively for possible and definitive SE patterns and background features (frequency, continuity, reactivity, and voltage)...
December 2023: Epileptic Disorders: International Epilepsy Journal with Videotape
https://read.qxmd.com/read/37774611/block-copolymer-derived-recessed-nanodisk-array-electrodes-for-electrochemical-detection-of-%C3%AE-lactam-antibiotics
#36
JOURNAL ARTICLE
Pratik Kolhe, Maitri Shah, Akash Nathani, Chandra Shekhar Sharma, Sonu Gandhi
Antimicrobial resistance (AMR) is one of the major socio-economic factors contributing to public health. β-lactams are most commonly prescribed drugs for variety of bacterial infections. Frequent use of antibiotics leads to AMR in humans and animals. The present work is focused on developing an electro-immunosensor to control and regulate the excessive use of antibiotics in animal-based food products. An amphiphilic block co-polymer poly(ethylene oxide-block-methyl methacrylate)(PEO-b-PMMA) was used to fabricate recessed nano-disk array electrode (RNE) and immobilized with Pen-Ab and Cef-Ab antibodies...
September 22, 2023: Food Chemistry
https://read.qxmd.com/read/37713626/differences-in-atrial-substrate-localization-using-lge-mri-electrogram-voltage-and-conduction-velocity-a-cohort-study-using-a-consistent-anatomical-reference-frame-in-patients-with-persistent-atrial-fibrillation
#37
JOURNAL ARTICLE
Deborah Nairn, Martin Eichenlaub, Björn Müller-Edenborn, Taiyuan Huang, Heiko Lehrmann, Claudia Nagel, Luca Azzolin, Giorgio Luongo, Rosa M Figueras Ventura, Barbara Rubio Forcada, Anna Vallès Colomer, Dirk Westermann, Thomas Arentz, Olaf Dössel, Axel Loewe, Amir Jadidi
BACKGROUND AND AIMS: Electro-anatomical voltage, conduction velocity (CV) mapping and late gadolinium enhancement magnetic resonance imaging (LGEMRI) have been correlated with atrial cardiomyopathy (ACM). However, the comparability between these modalities remains unclear. Aims: (1) Compare pathological substrate extent and location between current modalities. (2) Establish spatial histograms in a cohort. (3) Develop a new estimated optimised image intensity threshold (EOIIT) for LGE-MRI identifying patients with ACM...
September 15, 2023: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/37639829/cost-effectiveness-of-harness-mri-protocol-in-focal-drug-resistant-epilepsy-in-a-limited-resources-country-an-egyptian-study
#38
JOURNAL ARTICLE
Nirmeen A Kishk, Reham Shamloul, Mona K Moawad, Hussein Hamdi, Ahmed A Morsy, Michael Baghdadi, Mina Rizkallah, Amani Nawito, Mohammad Edrees Mohammad, Rehab Magdy, Enas Alsayyad, Alshimaa S Othman, Amr M Fouad, Haytham Rizk
OBJECTIVES: The international league against epilepsy (ILAE) recommended the harmonized neuroimaging of epilepsy structural sequences (HARNESS-MRI) to improve the detection of epileptogenic lesions in patients with focal drug-resistant epilepsy (DRE). The application of this protocol is still limited in low-resource countries, mainly due to apparent high costs. We aimed to evaluate the cost-effectiveness of the HARNESS-MRI protocol in Egypt and highlighted our experience. METHODS: Patients diagnosed with focal DRE at Cairo University epilepsy clinic underwent both conventional MRI (c-MRI) and HARNESS-MRI...
August 18, 2023: Clinical Neurology and Neurosurgery
https://read.qxmd.com/read/37639155/safety-feasibility-and-quality-of-thulium-laser-en-bloc-resection-for-treatment-of-non-muscle-invasive-bladder-cancer
#39
JOURNAL ARTICLE
Ahmed Assem, Ayman Kassem, Mohamed Sherif, Amr Lotfi, Mohamed Abdelwahed
BACKGROUND: Trans-Urethral Resection of Bladder Tumors (TURBT) is a critical step in diagnosis, staging and treatment of bladder tumors. Conventional TURBT (cTURBT) involves the electro-resection of the tumor into small fragments. This technique leads to concerns about the completeness of resection, under-staging, bleeding, cancer cell implantation, and most importantly, risk of tumour recurrence. To circumvent this, laser en-bloc resection of bladder tumors has been introduced...
August 28, 2023: International Urology and Nephrology
https://read.qxmd.com/read/37630959/a-combined-plasmonic-and-electrochemical-aptasensor-based-on-gold-nanopit-arrays-for-the-detection-of-human-serum-albumin
#40
JOURNAL ARTICLE
Ruifeng Zhu, Gabriela Figueroa-Miranda, Lei Zhou, Ziheng Hu, Bohdan Lenyk, Sven Ingebrandt, Andreas Offenhäusser, Dirk Mayer
Electrochemical and optical platforms are commonly employed in designing biosensors. However, one signal readout can easily lead to inaccuracies due to the effect of nonstandard test procedures, different operators, and experimental environments. We have developed a dual-signal protocol that combined two transducer principles in one aptamer-based biosensor by simultaneously performing electrochemical- and extraordinary optical transmission (EOT)-based plasmonic detection using gold nanopit arrays (AuNpA). Compared with full hole structures, we found that nanopits, that did not fully penetrate the gold film, not only exhibited a better plasmonic bandwidth and refractive index sensitivity both in the finite-difference time-domain simulation and in experiments by shielding the gold/quartz mode but also enlarged the electrochemical active surface area...
August 19, 2023: Nanomaterials
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