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https://www.readbyqxmd.com/read/28370567/vertically-oriented-and-shape-tailored-electrocatalytic-metal-nanowire-arrays-for-enzyme-free-galactosemia-rapid-diagnosis
#1
Laura García-Carmona, María Cristina González, Alberto Escarpa
Metallic catalytic nanowires such as nickel and copper nanowires (NWs) for electrochemical detection of carbohydrates involved in metabolic rare diseases are proposed. NWs were electrodeposited using a polycarbonate membrane template, which was cut with the desired shape, stuck in double-sided adhesive tape, pasted into a non-conductive substrate and in situ removed. This simple and versatile approach allowed to obtain NWs vertically oriented (v-NWs), which are contained in the double-sided adhesive tape, becoming highly versatile...
April 3, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28370452/linbo3-pr-3-a-multipiezo-material-with-simultaneous-piezoelectricity-and-sensitive-piezoluminescence
#2
Dong Tu, Chao-Nan Xu, Akihito Yoshida, Masayoshi Fujihala, Jou Hirotsu, Xu-Guang Zheng
Red-emitting piezoluminescence (elasticoluminescence) is achieved by doping rare earth Pr(3+) into the well-known piezoelectric matrix, LiNbO3 . By precisely tuning the Li/Nb ratio in nonstoichiometric Li x NbO3 :Pr(3+) , a material that exhibits an unusually high piezoluminescence intensity, which far exceeds that of any well-known piezoelectric material, is produced. Li x NbO3 :Pr(3+) shows excellent strain sensitivity at the lowest strain level, with no threshold for stress sensing. These multipiezo properties of sensitive piezoluminescence in a piezoelectric matrix are ideal for microstress sensing, damage diagnosis, electro-mechano-optical energy conversion, and multifunctional control in optoelectronics...
April 3, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28356764/study-of-nasal-exhaled-nitric-oxide-levels-in-diagnosis-of-allergic-rhinitis-in-subjects-with-and-without-asthma
#3
Sy Duong-Quy, Thuc Vu-Minh, Thong Hua-Huy, Tram Tang-Thi-Thao, Khiet Le-Quang, Dinh Tran-Thanh, Nhu Doan-Thi-Quynh, Nhat-Nam Le-Dong, Timothy J Craig, Anh-Tuan Dinh-Xuan
BACKGROUND: The measure of fractional exhaled nitric oxide (FENO) in the airways is a useful tool to guide the diagnosis and titration of inhaled corticosteroids in patients with asthma. However, its role in diagnosis of allergic rhinitis (AR), especially in subjects with asthma, is not well established. OBJECTIVE: To study the cutoff of nasal FENO in the diagnosis of subjects with AR and AR-asthma compared to age-matched subjects without AR or asthma and its correlations with the clinical and functional characteristics...
2017: Journal of Asthma and Allergy
https://www.readbyqxmd.com/read/28335260/a-label-free-microelectrode-array-based-on-one-step-synthesis-of-chitosan-multi-walled-carbon-nanotube-thionine-for-ultrasensitive-detection-of-carcinoembryonic-antigen
#4
Huiren Xu, Yang Wang, Li Wang, Yilin Song, Jinping Luo, Xinxia Cai
Carcinoembryonic antigen (CEA) has been an extensively used tumor marker responsible for clinical early diagnosis of cervical carcinomas, and pancreatic, colorectal, gastric and lung cancer. Combined with micro-electro mechanical system (MEMS) technology, it is important to develop a novel immune microelectrode array (MEA) not only for rapid analysis of serum samples, but also for cell detection in vitro and in vivo. In this work, we depict a simple approach to modify chitosan-multi-walled carbon nanotubes-thionine (CS-MWCNTs-THI) hybrid film through one-step electrochemical deposition and the CS-MWCNTs-THI hybrid films are successfully employed to immobilize anti-CEA for fabricating simple, label-free, and highly sensitive electro-chemical immune MEAs...
July 11, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28328288/the-role-of-mf-erg-in-the-diagnosis-and-treatment-of-age-related-macular-degeneration-electrophysiological-features-of-amd
#5
Marilita M Moschos, Eirini Nitoda
INTRODUCTION: Age-related macular cegeneration (AMD) is the leading cause of visual dysfunction worldwide, affecting 9-25% of individuals between 65 and 75 years old. METHODS: We have reviewed the published articles investigating the role of multifocal electroretinogram (mf-ERG) in the diagnosis and treatment of AMD. RESULTS: Visual evoked potentials have revealed decreased amplitudes and higher latencies in patients with AMD, while the degeneration of photoreceptors and abnormalities of retinal pigment epithelium can be identified by electro-oculogram recordings...
March 22, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28315816/longest-gallbladder-a-case-report
#6
Rahul Yadav, Jeevan Kankaria
INTRODUCTION: A gallbladder mucocele is the distention of the gallbladder by an inappropriate accumulation of mucus. Decreased bile flow, decreased gallbladder motility, and altered absorption of water from the gallbladder lumen are predisposing factors to biliary sludge. However, it is more likely to be a small part of a complex disease process involving inflammation of the gallbladder wall and changes to the lining of the gallbladder changing the consistency of its secretions. We would like to present a case of mucocele gallbladder operated successfully by laparoscopic cholecystectomy...
February 28, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28299696/finger-powered-electro-digital-microfluidics
#7
Cheng Peng, Y Sungtaek Ju
Portable microfluidic devices are promising for point-of-care (POC) diagnosis and bio- and environmental surveillance in resource-constrained or non-laboratory environments. Lateral-flow devices, some built off paper or strings, have been widely developed but the fixed layouts of their underlying wicking/microchannel structures limit their flexibility and present challenges in implementing multistep reactions. Digital microfluidics can circumvent these difficulties by addressing discrete droplets individually...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28238390/electro-clinical-etiological-associations-of-epilepsia-partialis-continua-in-57-chinese-children
#8
Hui Li, Jiao Xue, Ping Qian, Yuehua Zhang, Xinhua Bao, Xiaoyan Liu, Zhixian Yang
OBJECTIVE: Epilepsia partialis continua (EPC) was one type of focal status epilepticus. The aim of this study was to analyze the clinical and electroencephalography (EEG) characteristics, and outcome of 57 child-onset patients with EPC according to different etiologies, and further explore the electro-clinical-etiological associations. METHODS: We retrospectively reviewed 57 children diagnosed with EPC in our department over last ten years. Etiology, clinical and EEG data, and outcome were categorized and analyzed...
June 2017: Brain & Development
https://www.readbyqxmd.com/read/28171686/the-relationship-between-procalcitonin-and-thyroid-autoantibodies-in-patients-with-autoimmune-thyroiditis
#9
Ali Oncul, Ihsan Ates, Mehmet Fettah Arikan, Nisbet Yilmaz, Canan Topcuoglu, Fatma Meric Yilmaz, Mustafa Altay
BACKGROUND: The aim of this study is to investigate the serum levels of procalcitonin and its association with autoantibodies in patients with euthyroid Hashimoto's thyroiditis. METHODS: A total of 80 participants were included in the study; 40 of which were newly diagnosed with Hashimoto's thyroiditis, aged over 18, and 40 of which were healthy volunteers. The serum levels of procalcitonin were measured by enzyme-linked immunosorbent assay kit. Thyroid function tests were analyzed in hormone laboratory with Electro-chemiluminescence immunoassay...
February 7, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/27998453/-clinical-features-of-neurosyphilis-with-optic-neuritis-as-an-initial-finding
#10
S S Cao, H Y Li, Q G Xu, S Y Tan, S H Wei
Objective: To study the characteristics of neurosyphilis with optic neuritis as an initial finding. Methods: Retrospective analysis of clinical data and laboratory testing results of 16 cases (27 eyes) with optic neuritis as an initial finding of neurosyphilis from October 2010 to March 2015 in General Hospital of People's Liberation Army was made. Results: Six-teen patients (12 males, 4 females) were collected, the median age of patients was 47 (range 33 to 65) years ,the mean age was (49.63±9.05) years. Treponema pallidum particle agglutination assay (TPPA) analysis was positive in all of the patients and rapid plasma reagin (RPR) test was positive in 14 patients (2 patients did not test)...
December 11, 2016: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/27866080/highly-sensitive-detection-of-cancer-cells-with-an-electrochemical-cytosensor-based-on-boronic-acid-functional-polythiophene
#11
Muamer Dervisevic, Mehmet Senel, Tugba Sagir, Sevim Isik
The detection of cancer cells through important molecular recognition target such as sialic acid is significant for the clinical diagnosis and treatment. There are many electrochemical cytosensors developed for cancer cells detection but most of them have complicated fabrication processes which results in poor reproducibility and reliability. In this study, a simple, low-cost, and highly sensitive electrochemical cytosensor was designed based on boronic acid-functionalized polythiophene. In cytosensors fabrication simple single-step procedure was used which includes coating pencil graphite electrode (PGE) by means of electro-polymerization of 3-Thienyl boronic acid and Thiophen...
April 15, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/27858695/carpal-tunnel-syndrome-investigating-the-sensitivity-of-initial-diagnosis-with-electro-diagnostic-tests-in-600-cases-and-associated-risk-factors-especially-manual-milking
#12
Abdulkadir Tunç, Belma Doğan Güngen
BACKGROUND: Electro-diagnostic studies are the most reliable methods in diagnosis of carpal tunnel syndrome (CTS). Although there are many risk factors associated with CTS, there are a limited number of studies in the literature indicating that manual milking, which is frequently seen in Turkey, is a risk factor for CTS. OBJECTIVE: The purpose of this study was to evaluate demographic findings of cases referred due to initial diagnosis of CTS as well as aetiological data especially manual milking and to investigate the sensitivity of initial diagnosis of CTS...
2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/27822276/demographic-and-diagnostic-features-of-3147-inpatients-with-mood-disorders-in-iran
#13
Atefeh Ghanbari Jolfaei, Pari Ghadamgahi, Masoud Ahmadzad-Asl, Amir Shabani
OBJECTIVES: To assess and compare demographic and diagnostic characteristics of inpatients with mood disorders in Iran. MATERIALS AND METHODS: We collected the demographic, clinical, and treatment characteristics of patients, who were hospitalized during five years from April 2006 to March 2010, in Iran hospital of psychiatry, a residency training center to evaluate the general clinical picture of the disorder. RESULTS: Overall, 95.3% of subjects had a diagnosis of bipolar I disorder (BID), 2...
September 2016: Iranian Journal of Psychiatry and Behavioral Sciences
https://www.readbyqxmd.com/read/27631726/plasma-mir-22-3p-mir-642b-3p-and-mir-885-5p-as-diagnostic-biomarkers-for-pancreatic-cancer
#14
Neveen Abd El Moneim Hussein, Zenat A El Kholy, Medhat M Anwar, Mohamed A Ahmad, Shaymaa M Ahmad
BACKGROUND: Diagnosis of pancreatic cancer (PC) by using sensitive and specific biomarkers is considered necessary. MiRNAs are master regulators of gene expression and several biological processes, and they are dysregulated in various cancers, where they play a vital role in either cancer progression or suppression. So, this study was designed to investigate the role of plasma miR-22-3p, miR-642b-3p and miR-885-5p expression as possible diagnostic markers in PC patients as compared to serum CA19-9...
January 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/27577954/electronic-activation-of-a-dna-nanodevice-using-a-multilayer-nanofilm
#15
Hyejoong Jeong, Simona Ranallo, Marianna Rossetti, Jiwoong Heo, Jooseok Shin, Kwangyong Park, Francesco Ricci, Jinkee Hong
A method to control activation of a DNA nanodevice by supplying a complementary DNA (cDNA) strand from an electro-responsive nanoplatform is reported. To develop functional nanoplatform, hexalayer nanofilm is precisely designed by layer-by-layer assembly technique based on electrostatic interaction with four kinds of materials: Hydrolyzed poly(β-amino ester) can help cDNA release from the film. A cDNA is used as a key building block to activate DNA nanodevice. Reduced graphene oxides (rGOs) and the conductive polymer provide conductivity...
August 31, 2016: Small
https://www.readbyqxmd.com/read/27538913/analysis-of-multiple-sclerosis-patients-with-electrophysiological-and-structural-tests
#16
Mualla Hamurcu, Gürdal Orhan, Murat Sinan Sarıcaoğlu, Semra Mungan, Zeynep Duru
We aimed to analyze the effects of progressive myelin loss and neurodegeneration seen in patients with multiple sclerosis (MS) on visual tract with electrophysiological and structural tests. Fifty-one patients diagnosed with MS in the Neurology Department were followed up in neuro-ophthalmology outpatient clinic irrespective of their visual symptoms, and were included in our study. The patients were classified as the ones with the history of optic neuritis (group II) and ones without the history (group I) of optic neuritis...
August 18, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/27417043/electroencephalographic-characteristics-of-epileptic-seizures-in-preterm-neonates
#17
Soňa Janáčková, Steward Boyd, Elissa Yozawitz, Tammy Tsuchida, Marie-Dominique Lamblin, Sophie Gueden, Ronit Pressler
OBJECTIVE: Although seizures are more common in the neonatal period than in any other stage of childhood, those in preterm neonates are still poorly described. The aim of this study was to assess electro-clinical characteristics of seizures occurring before a corrected age of 40weeks in neonates born prematurely. METHOD: Retrospective analysis of EEG-documented seizures in neonates born prematurely. Seizures in a group of term neonates served as controls. RESULTS: Fifty-six prematurely born and 46 term born neonates were included...
August 2016: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/27382202/multiple-biomarkers-to-assess-the-pathophysiological-state-in-critically-ill-patients-with-sepsis
#18
Prashanth Ashok Kumar, Usha Anand
Sepsis is associated with various metabolic derangements as a consequence of inflammatory response, ischemia and oxidative stress. Four parameters of relevance are procalcitonin (PCT), ischemia modified albumin (IMA) pH and lactate. The study was carried out to highlight the concomitant occurrence of sepsis, ischemia and lactic acidosis, all of which could have deleterious effects on organ function. 26 critically ill patients with a provisional diagnosis of sepsis were the test subjects. The control group had 25 apparently healthy volunteers...
July 2016: Indian Journal of Clinical Biochemistry: IJCB
https://www.readbyqxmd.com/read/27376049/the-role-of-median-nerve-terminal-latency-index-in-the-diagnosis-of-carpal-tunnel-syndrome-in-comparison-with-other-electrodiagnostic-parameters
#19
Babak Vahdatpour, Saeid Khosrawi, Maryam Chatraei
BACKGROUND: Carpal tunnel syndrome (CTS) considers the most common compression neuropathy, which nerve conduction studies (NCSs) used for its detection routinely and universally. This study was performed to determine the value of the median TLI and other NCS variables and to investigate their sensitivity and specificity in the diagnosis of CTS. MATERIALS AND METHODS: The study was carried out among 100 hands of healthy volunteers and 50 hands of patients who had a positive history of paresthesia and numbness in upper extremities...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/27353700/-description-of-clinical-pathological-concordance-and-patient-satisfaction-in-minor-surgery-in-a-primary-care-centre
#20
María Gabriela Ramírez Arriola, Naima Hamido Mohamed, Juan José Abad Vivás-Pérez, Juan José Bretones Alcaráz, Juan Manuel García Torrecillas, Evelyn Huber
AIM: To describe the minor surgery (MS) characteristics in a Primary Care (PC) centre, and to evaluate the clinical pathological concordance and patient satisfaction. DESIGN: Descriptive and retrospective study. SETTING: Primary Care, urban health care centre, Almería, Spain. PARTICIPANTS: The population were the patients belonging to urban Primary Health Care centre, referred by their family physicians or paediatricians for the performing of MS during year 2013, and who consented to the intervention...
June 25, 2016: Atencion Primaria
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