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JOURNAL ARTICLE
X Vendrell, P de Castro, L Escrich, N Grau, R Gonzalez-Martin, A Quiñonero, M J Escribá, F Domínguez
STUDY QUESTION: How do transcriptomics vary in haploid human androgenote embryos at single cell level in the first four cell cycles of embryo development? SUMMARY ANSWER: Gene expression peaks at the fourth cell cycle, however some androcytes exhibit unique transcriptional behaviors. WHAT IS KNOWN ALREADY: The developmental potential of an embryo is determined by the competence of the oocyte and the sperm. However, studies of the contribution of the paternal genome using pure haploid androgenotes are very scarce...
April 15, 2024: Human Reproduction
#22
JOURNAL ARTICLE
Filipe Ferrari, Anderson D da Silveira, Patrícia K Ziegelmann, Haroldo Aleixo, Guilherme D Dilda, Luiz G M Emed, Flávia C O Magalhães, Fernando B Cardoso, Henrique C da Silva, Felipe E F Guerra, Luciano G Soares, Fernando Bassan, Fabrício Braga, Artur H Herdy, Victor Froelicher, Ricardo Stein
OBJECTIVES: To evaluate the prevalence of abnormal ECG findings and their association with imaging results in male Brazilian football players. METHODS: The 'B-Pro Foot ECG' is a multicentre observational study conducted in 82 Brazilian professional clubs. It analysed 6125 players aged 15-35 years (2496 white, 2004 mixed-race and 1625 black individuals) who underwent cardiovascular screening from 2002 to 2023. All ECGs were reviewed by two experienced cardiologists in the athlete's care...
April 15, 2024: British Journal of Sports Medicine
#23
JOURNAL ARTICLE
Fred Cooper, Avinash Khare, John F Dawson, Efstathios G Charalampidis, Avadh Saxena
In this work, we discuss an application of the "inverse problem" method to find the external trapping potential, which has particular N trapped soliton-like solutions of the Gross-Pitaevskii equation (GPE) also known as the cubic nonlinear Schrödinger equation (NLSE). This inverse method assumes particular forms for the trapped soliton wave function, which then determines the (unique) external (confining) potential. The latter renders these assumed waveforms exact solutions of the GPE (NLSE) for both attractive (g<0) and repulsive (g>0) self-interactions...
April 1, 2024: Chaos
#24
JOURNAL ARTICLE
A remarkable genetic shift in a transmitted/founder virus broadens antibody responses against HIV-1.
Swati Jain, Gherman Uritskiy, Marthandan Mahalingam, Himanshu Batra, Subhash Chand, Hung V Trinh, Charles Beck, Woong-Hee Shin, Wadad Alsalmi, Gustavo Kijak, Leigh A Eller, Jerome Kim, Daisuke Kihara, Sodsai Tovanabutra, Guido Ferrari, Merlin L Robb, Mangala Rao, Venigalla B Rao
A productive HIV-1 infection in humans is often established by transmission and propagation of a single transmitted/founder (T/F) virus, which then evolves into a complex mixture of variants during the lifetime of infection. An effective HIV-1 vaccine should elicit broad immune responses in order to block the entry of diverse T/F viruses. Currently, no such vaccine exists. An in-depth study of escape variants emerging under host immune pressure during very early stages of infection might provide insights into such a HIV-1 vaccine design...
April 15, 2024: ELife
#25
JOURNAL ARTICLE
M Ablikim, M N Achasov, P Adlarson, X C Ai, R Aliberti, A Amoroso, M R An, Q An, Y Bai, O Bakina, I Balossino, Y Ban, H-R Bao, V Batozskaya, K Begzsuren, N Berger, M Berlowski, M Bertani, D Bettoni, F Bianchi, E Bianco, A Bortone, I Boyko, R A Briere, A Brueggemann, H Cai, X Cai, A Calcaterra, G F Cao, N Cao, S A Cetin, J F Chang, T T Chang, W L Chang, G R Che, G Chelkov, C Chen, Chao Chen, G Chen, H S Chen, M L Chen, S J Chen, S L Chen, S M Chen, T Chen, X R Chen, X T Chen, Y B Chen, Y Q Chen, Z J Chen, S K Choi, X Chu, G Cibinetto, S C Coen, F Cossio, J J Cui, H L Dai, J P Dai, A Dbeyssi, R E de Boer, D Dedovich, Z Y Deng, A Denig, I Denysenko, M Destefanis, F De Mori, B Ding, X X Ding, Y Ding, Y Ding, J Dong, L Y Dong, M Y Dong, X Dong, M C Du, S X Du, Z H Duan, P Egorov, Y H Fan, J Fang, S S Fang, W X Fang, Y Fang, Y Q Fang, R Farinelli, L Fava, F Feldbauer, G Felici, C Q Feng, J H Feng, K Fischer, M Fritsch, C D Fu, J L Fu, Y W Fu, H Gao, Y N Gao, Yang Gao, S Garbolino, I Garzia, P T Ge, Z W Ge, C Geng, E M Gersabeck, A Gilman, K Goetzen, L Gong, W X Gong, W Gradl, S Gramigna, M Greco, M H Gu, Y T Gu, C Y Guan, Z L Guan, A Q Guo, L B Guo, M J Guo, R P Guo, Y P Guo, A Guskov, J Gutierrez, T T Han, W Y Han, X Q Hao, F A Harris, K K He, K L He, F H H Heinsius, C H Heinz, Y K Heng, C Herold, T Holtmann, P C Hong, G Y Hou, X T Hou, Y R Hou, Z L Hou, B Y Hu, H M Hu, J F Hu, T Hu, Y Hu, G S Huang, K X Huang, L Q Huang, X T Huang, Y P Huang, T Hussain, N Hüsken, N In der Wiesche, M Irshad, J Jackson, S Jaeger, S Janchiv, J H Jeong, Q Ji, Q P Ji, X B Ji, X L Ji, Y Y Ji, X Q Jia, Z K Jia, H J Jiang, P C Jiang, S S Jiang, T J Jiang, X S Jiang, Y Jiang, J B Jiao, Z Jiao, S Jin, Y Jin, M Q Jing, X M Jing, T Johansson, X Kui, S Kabana, N Kalantar-Nayestanaki, X L Kang, X S Kang, M Kavatsyuk, B C Ke, V Khachatryan, A Khoukaz, R Kiuchi, R Kliemt, O B Kolcu, B Kopf, M Kuessner, A Kupsc, W Kühn, J J Lane, P Larin, A Lavania, L Lavezzi, T T Lei, Z H Lei, H Leithoff, M Lellmann, T Lenz, C Li, C Li, C H Li, Cheng Li, D M Li, F Li, G Li, H Li, H B Li, H J Li, H N Li, Hui Li, J R Li, J S Li, J W Li, Ke Li, L J Li, L K Li, Lei Li, M H Li, P R Li, Q X Li, S X Li, T Li, W D Li, W G Li, X H Li, X L Li, Xiaoyu Li, Y G Li, Z J Li, Z X Li, C Liang, H Liang, H Liang, Y F Liang, Y T Liang, G R Liao, L Z Liao, Y P Liao, J Libby, A Limphirat, D X Lin, T Lin, B J Liu, B X Liu, C Liu, C X Liu, F H Liu, Fang Liu, Feng Liu, G M Liu, H Liu, H B Liu, H M Liu, Huanhuan Liu, Huihui Liu, J B Liu, J Y Liu, K Liu, K Y Liu, Ke Liu, L Liu, L C Liu, Lu Liu, M H Liu, P L Liu, Q Liu, S B Liu, T Liu, W K Liu, W M Liu, X Liu, Y Liu, Y Liu, Y B Liu, Z A Liu, Z Q Liu, X C Lou, F X Lu, H J Lu, J G Lu, X L Lu, Y Lu, Y P Lu, Z H Lu, C L Luo, M X Luo, T Luo, X L Luo, X R Lyu, Y F Lyu, F C Ma, H Ma, H L Ma, J L Ma, L L Ma, M M Ma, Q M Ma, R Q Ma, X Y Ma, Y Ma, Y M Ma, F E Maas, M Maggiora, S Malde, Q A Malik, A Mangoni, Y J Mao, Z P Mao, S Marcello, Z X Meng, J G Messchendorp, G Mezzadri, H Miao, T J Min, R E Mitchell, X H Mo, B Moses, N Yu Muchnoi, J Muskalla, Y Nefedov, F Nerling, I B Nikolaev, Z Ning, S Nisar, Q L Niu, W D Niu, Y Niu, S L Olsen, Q Ouyang, S Pacetti, X Pan, Y Pan, A Pathak, P Patteri, Y P Pei, M Pelizaeus, H P Peng, Y Y Peng, K Peters, J L Ping, R G Ping, S Plura, V Prasad, F Z Qi, H Qi, H R Qi, M Qi, T Y Qi, S Qian, W B Qian, C F Qiao, J J Qin, L Q Qin, X S Qin, Z H Qin, J F Qiu, S Q Qu, C F Redmer, K J Ren, A Rivetti, M Rolo, G Rong, Ch Rosner, S N Ruan, N Salone, A Sarantsev, Y Schelhaas, K Schoenning, M Scodeggio, K Y Shan, W Shan, X Y Shan, J F Shangguan, L G Shao, M Shao, C P Shen, H F Shen, W H Shen, X Y Shen, B A Shi, H C Shi, J L Shi, J Y Shi, Q Q Shi, R S Shi, X Shi, J J Song, T Z Song, W M Song, Y J Song, Y X Song, S Sosio, S Spataro, F Stieler, Y J Su, G B Sun, G X Sun, H Sun, H K Sun, J F Sun, K Sun, L Sun, S S Sun, T Sun, W Y Sun, Y Sun, Y J Sun, Y Z Sun, Z T Sun, Y X Tan, C J Tang, G Y Tang, J Tang, Y A Tang, L Y Tao, Q T Tao, M Tat, J X Teng, V Thoren, W H Tian, W H Tian, Y Tian, Z F Tian, I Uman, Y Wan, S J Wang, B Wang, B L Wang, Bo Wang, C W Wang, D Y Wang, F Wang, H J Wang, J P Wang, K Wang, L L Wang, M Wang, Meng Wang, N Y Wang, S Wang, S Wang, T Wang, T J Wang, W Wang, W Wang, W P Wang, X Wang, X F Wang, X J Wang, X L Wang, Y Wang, Y D Wang, Y F Wang, Y L Wang, Y N Wang, Y Q Wang, Yaqian Wang, Yi Wang, Z Wang, Z L Wang, Z Y Wang, Ziyi Wang, D Wei, D H Wei, F Weidner, S P Wen, C W Wenzel, U Wiedner, G Wilkinson, M Wolke, L Wollenberg, C Wu, J F Wu, L H Wu, L J Wu, X Wu, X H Wu, Y Wu, Y H Wu, Y J Wu, Z Wu, L Xia, X M Xian, T Xiang, D Xiao, G Y Xiao, S Y Xiao, Y L Xiao, Z J Xiao, C Xie, X H Xie, Y Xie, Y G Xie, Y H Xie, Z P Xie, T Y Xing, C F Xu, C J Xu, G F Xu, H Y Xu, Q J Xu, Q N Xu, W Xu, W L Xu, X P Xu, Y C Xu, Z P Xu, Z S Xu, F Yan, L Yan, W B Yan, W C Yan, X Q Yan, H J Yang, H L Yang, H X Yang, Tao Yang, Y Yang, Y F Yang, Y X Yang, Yifan Yang, Z W Yang, Z P Yao, M Ye, M H Ye, J H Yin, Z Y You, B X Yu, C X Yu, G Yu, J S Yu, T Yu, X D Yu, C Z Yuan, L Yuan, S C Yuan, Y Yuan, Z Y Yuan, C X Yue, A A Zafar, F R Zeng, S H Zeng, X Zeng, Y Zeng, Y J Zeng, X Y Zhai, Y C Zhai, Y H Zhan, A Q Zhang, B L Zhang, B X Zhang, D H Zhang, G Y Zhang, H Zhang, H C Zhang, H H Zhang, H H Zhang, H Q Zhang, H Y Zhang, J Zhang, J Zhang, J J Zhang, J L Zhang, J Q Zhang, J W Zhang, J X Zhang, J Y Zhang, J Z Zhang, Jianyu Zhang, L M Zhang, L Q Zhang, Lei Zhang, P Zhang, Q Y Zhang, Shuihan Zhang, Shulei Zhang, X D Zhang, X M Zhang, X Y Zhang, Y Zhang, Y Zhang, Y T Zhang, Y H Zhang, Yan Zhang, Yao Zhang, Z D Zhang, Z H Zhang, Z L Zhang, Z Y Zhang, Z Y Zhang, G Zhao, J Y Zhao, J Z Zhao, Lei Zhao, Ling Zhao, M G Zhao, R P Zhao, S J Zhao, Y B Zhao, Y X Zhao, Z G Zhao, A Zhemchugov, B Zheng, J P Zheng, W J Zheng, Y H Zheng, B Zhong, X Zhong, H Zhou, L P Zhou, X Zhou, X K Zhou, X R Zhou, X Y Zhou, Y Z Zhou, J Zhu, K Zhu, K J Zhu, L Zhu, L X Zhu, S H Zhu, S Q Zhu, T J Zhu, W J Zhu, Y C Zhu, Z A Zhu, J H Zou, J Zu
We present cross sections for the reaction e^{+}e^{-}→K_{S}^{0}K_{L}^{0} at center-of-mass energies ranging from 3.51 to 4.95 GeV using data samples collected in the BESIII experiment, corresponding to a total integrated luminosity of 26.5 fb^{-1}. The ratio of neutral-to-charged kaon form factors at large momentum transfers (12<Q^{2}<25 GeV^{2}) is determined to be 0.21±0.01, which indicates a small but significant effect of flavor-SU(3) breaking in the kaon wave function, and, consequently, excludes the possibility that flavor-SU(3) breaking is the primary reason for the strong experimental violation of the pQCD prediction |F(π^{±})|/|F(K^{±})|=f_{π}^{2}/f_{K}^{2}, where F(π^{±}) and F(K^{±}) are the form factors, and f_{π} and f_{K} are the decay constants of charged pions and kaons, respectively...
March 29, 2024: Physical Review Letters
#26
JOURNAL ARTICLE
Ekaterina E Galenko, Mikhail S Novikov, Alexander S Bunev, Alexander F Khlebnikov
Easy-to-handle N -hydroxyacridinecarbimidoyl chloride hydrochlorides were synthesized as convenient nitrile oxide precursors in the preparation of 3-(acridin-9/2-yl)isoxazole derivatives via 1,3-dipolar cycloaddition with terminal alkynes, 1,1-dichloroethene, and acrylonitrile. Azirines with an acridin-9/2-yl substituent attached directly or via the 1,2,3-triazole linker to the azirine C2 were also synthesized. The three-membered rings of the acridine-azirine hybrids were found to be resistant to irradiation in the UV/visible boundary region, despite their long-wave absorption at 320-420 nm, indicating that the acridine moiety cannot be used as an antenna to transfer light energy to generate nitrile ylides from azirines for photoclick cycloaddition...
March 29, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
#27
JOURNAL ARTICLE
Antonio F M Vainieri, Elisa Brando, Antonio De Vincentis, Giulia Di Pasquale, Valentina Flagiello, Paolo Gallo, Francesca Barone, Teresa Massaro Cenere, Evelyn Di Matteo, Antonio Picardi, Giovanni Galati
Acoustic radiation forced impulse (ARFI) is an integrated ultrasound method, measuring stiffness by point shear wave elastography. To evaluate the diagnostic performance of the ARFI of the liver and the spleen, combined with spleen dimension and platelet count, in predicting high-risk esophageal varices (HRVs) in cirrhotic patients, a prospective and cross-sectional study was conducted between February 2017 and February 2021. The following ratio scores were calculated based on ARFI measurements: ALSDP (ARFI Liver-Spleen Diameter-to-Platelet Ratio Score), ASSDP (ARFI Spleen-Spleen Diameter-to-Platelet Ratio Score), ASSAP (ARFI Spleen-Spleen Area-to-Platelet Ratio Score), and ALSAP (ARFI Liver-Spleen Area-to-Platelet Ratio Score)...
March 25, 2024: Diagnostics
#28
JOURNAL ARTICLE
Xinhang Wang, Ying Zhang, Haibin Yuan, Yanhui Lu
Cotton aphid Aphis gossypii Glover damages plants such as cotton directly by feeding on leaves and indirectly by transmitting viruses and excreting honeydew, which interferes with photosynthesis. The control of A. gossypii is still dominated by the frequent use of insecticides, which leads to a gradual increase in pesticide resistance in A. gossypii . Research is therefore needed on non-pesticide controls. In this study, seven plant essential oils (EOs) of Ocimum sanctum L., Ocimum basilicum L., Ocimum gratissimum L...
March 22, 2024: Plants (Basel, Switzerland)
#29
JOURNAL ARTICLE
Chang Hyeon Jeong, Hyunmi Lim, Jiye Lee, Hye Sun Lee, Jeonghun Ku, Youn Joo Kang
INTRODUCTION: Brain computer interface-based action observation (BCI-AO) is a promising technique in detecting the user's cortical state of visual attention and providing feedback to assist rehabilitation. Peripheral nerve electrical stimulation (PES) is a conventional method used to enhance outcomes in upper extremity function by increasing activation in the motor cortex. In this study, we examined the effects of different pairings of peripheral nerve electrical stimulation (PES) during BCI-AO tasks and their impact on corticospinal plasticity...
2024: Frontiers in Neuroscience
#30
JOURNAL ARTICLE
Amaranta Ramirez, David B Rivera, Adrian M Valadez, Samantha Mattis, Alison Cerezo
Objective: The COVID-19 global pandemic has created severe, long-lasting challenges to college students in the United States (US). In the present study, we assessed mental health symptomatology (depression, anxiety, life stress), academic challenges, and economic stress during the first wave of the Coronavirus pandemic. Method: A total sample of 361 college students ( M age = 22.26, SD = 5.56) was gathered from a community college ( N = 134) and mid-size public university ( N = 227) in Southwest US, both designated as Hispanic Serving Institutions...
July 2023: Community College Review
#31
JOURNAL ARTICLE
Christopher W Jones, Olivia Larson, Mathias Basner, David F Dinges
Healthy sleep of sufficient duration preserves mood and disturbed sleep is a risk factor for a range of psychiatric disorders. As adults commonly experience chronic sleep restriction (SR), an enhanced understanding of the dynamic relationship between sleep and mood is needed, including whether susceptibility to SR-induced mood disturbance differs between sexes. To address these gaps, data from N=221 healthy adults who completed one of two multi-day laboratory studies with identical 9-day SR protocols were analyzed...
April 11, 2024: Sleep
#32
JOURNAL ARTICLE
Jayantika Chakraborty, Sampurna Kundu
Discrimination is harmful action taken against individuals or groups to protect customary relations of power and privilege. Older adults are particularly vulnerable to experiences of discrimination that adversely affect their quality of life. We use data from the Longitudinal Ageing Study of India (LASI; Wave 1; 2017-2018) to examine different contextual forces that shape the experiences of discrimination in older adults in India, specifically gender, caste, and economic condition. We used the theory of intersectionality to hypothesize that economic condition, caste, and gender combine uniquely to engender perceived discrimination in older adults...
April 10, 2024: BMC Psychology
#33
JOURNAL ARTICLE
Aliakbar Sepehri, Alexandar Azenkeng, Mark R Hoffmann
Potential energy curves (PECs) were calculated for 21 and 18 electronic states of NdO and NdS molecules, respectively. In each case, static electron correlation effects were described by incomplete model space multiconfiguration self-consistent field wave functions based on an active space that included the most important valence orbitals. Dynamic electron correlation was included by the multireference second-order generalized Van Vleck perturbation theory method. Scalar-relativistic contributions were included by the effective core potential approach, using def2-TZVPP basis sets...
April 10, 2024: Journal of Physical Chemistry. A
#34
JOURNAL ARTICLE
Marco Av Silva, Ana Ps De Oliveira, Ana Cs Queiroz, Amanda O Spaziani, Leticia Ab Fernandes, Kleber A De Oliveira, Valquiria Da S Lopes, Manoel P Landim, Luciana N Cosenso-Martin, Jose F Vilela-Martin
INTRODUCTION: Equations can calculate pulse wave velocity (ePWV) from blood pressure values (BP) and age. The ePWV predicts cardiovascular events beyond carotid-femoral PWV. We aimed to evaluate the correlation between four different equations to calculate ePWV. METHODS: The ePWV was estimated utilizing mean BP (MBP) from office BP (MBPOBP) or 24-hour ambulatory BP (MBP24-hBP). We separated the whole sample into two groups: individuals with risk factors and healthy individuals...
2024: PloS One
#35
JOURNAL ARTICLE
Tomoaki Masuda, Atsushi Aoki, Tadashi Omoto, Kazuto Maruta
OBJECTIVES: Although risk factors for unsuccessful Maze procedure have been demonstrated, an appropriate patient selection is still controversial. In our institute, Maze procedure is indicated for those whom normal sinus rhythm (NSR) was reestablished by intraoperative direct cardioversion (DC) after ventricular unloading by total cardiopulmonary bypass. The purpose of this study was to evaluate the effectiveness of our indication criteria for Maze procedure in patients with mitral valve disease...
April 8, 2024: Journal of Cardiothoracic Surgery
#36
JOURNAL ARTICLE
Shun Li, Zong-Yuan Liu, Hao Li, Sijia Zhou, Jiaying Liu, Ningwei Sun, Kai-Fu Yang, Vanessa Dougados, Thomas Mangeat, Karine Belguise, Xi-Qiao Feng, Yiyao Liu, Xiaobo Wang
Actomyosin networks constrict cell area and junctions to alter cell and tissue shape. However, during cell expansion under mechanical stress, actomyosin networks are strengthened and polarized to relax stress. Thus, cells face a conflicting situation between the enhanced actomyosin contractile properties and the expansion behaviour of the cell or tissue. To address this paradoxical situation, we study late Drosophila oogenesis and reveal an unusual epithelial expansion wave behaviour. Mechanistically, Rac1 and Rho1 integrate basal pulsatile actomyosin networks with ruffles and focal adhesions to increase and then stabilize basal area of epithelial cells allowing their flattening and elongation...
April 8, 2024: Nature Communications
#37
JOURNAL ARTICLE
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Alvaro Curiel-Garcia, A Cole Edwards, Yingyun Wang, Bianca Lee, Margo Orlen, Sha Tian, Clint A Stalnecker, Kristina Drizyte-Miller, Marie Menard, Julien Dilly, Stephen A Sastra, Carmine F Palermo, Marie C Hasselluhn, Amanda R Decker-Farrell, Stephanie Chang, Lingyan Jiang, Xing Wei, Yu C Yang, Ciara Helland, Haley Courtney, Yevgeniy Gindin, Karl Muonio, Ruiping Zhao, Samantha B Kemp, Cynthia Clendenin, Rina Sor, William P Vostrejs, Priya S Hibshman, Amber M Amparo, Connor Hennessey, Matthew G Rees, Melissa M Ronan, Jennifer A Roth, Jens Brodbeck, Lorenzo Tomassoni, Basil Bakir, Nicholas D Socci, Laura E Herring, Natalie K Barker, Junning Wang, James M Cleary, Brian M Wolpin, John A Chabot, Michael D Kluger, Gulam A Manji, Kenneth Y Tsai, Miroslav Sekulic, Stephen M Lagana, Andrea Califano, Elsa Quintana, Zhengping Wang, Jacqueline A M Smith, Matthew Holderfield, David Wildes, Scott W Lowe, Michael A Badgley, Andrew J Aguirre, Robert H Vonderheide, Ben Z Stanger, Timour Baslan, Channing J Der, Mallika Singh, Kenneth P Olive
Broad-spectrum RAS inhibition holds the potential to benefit roughly a quarter of human cancer patients whose tumors are driven by RAS mutations1,2 . RMC-7977 is a highly selective inhibitor of the active GTP-bound forms of KRAS, HRAS, and NRAS, with affinity for both mutant and wild type (WT) variants (RAS(ON) multi-selective)3 . As >90% of human pancreatic ductal adenocarcinoma (PDAC) cases are driven by activating mutations in KRAS4 , we assessed the therapeutic potential of the RAS(ON) multi-selective inhibitor RMC-7977 in a comprehensive range of PDAC models...
April 8, 2024: Nature
#38
JOURNAL ARTICLE
Xuzhi Wang, Yuankai Zhang, Chathurangi H Pathiravasan, Nene C Ukonu, Jian Rong, Emelia J Benjamin, David D McManus, Martin G Larson, Ramachandran S Vasan, Naomi M Hamburg, Joanne M Murabito, Chunyu Liu, Gary F Mitchell
BACKGROUND: Short-term blood pressure variability (BPV) is associated with arterial stiffness in patients with hypertension. Few studies have examined associations between arterial stiffness and digital home BPV over a mid- to long-term time span, irrespective of underlying hypertension. OBJECTIVE: This study aims to investigate if arterial stiffness traits were associated with subsequent mid- to long-term home BPV in the electronic Framingham Heart Study (eFHS)...
April 8, 2024: JMIR Cardio
#39
JOURNAL ARTICLE
Joshua T B Williams, Kate Kurlandsky, Kristin Breslin, M Joshua Durfee, Amy Stein, Laura Hurley, Jo Ann Shoup, Liza M Reifler, Matthew F Daley, Bruno J Lewin, Kristin Goddard, Michelle L Henninger, Jennifer C Nelson, Gabriela Vazquez-Benitez, Kayla E Hanson, Candace C Fuller, Eric S Weintraub, Michael M McNeil, Simon J Hambidge
IMPORTANCE: Pregnant people and infants are at high risk of severe COVID-19 outcomes. Understanding changes in attitudes toward COVID-19 vaccines among pregnant and recently pregnant people is important for public health messaging. OBJECTIVE: To assess attitudinal trends regarding COVID-19 vaccines by (1) vaccination status and (2) race, ethnicity, and language among samples of pregnant and recently pregnant Vaccine Safety Datalink (VSD) members from 2021 to 2023...
April 1, 2024: JAMA Network Open
#40
JOURNAL ARTICLE
Lu Li, Guanghua Pan, Jintao Wang, Jiaqi Ren, Qi Fang, Hua Xu
OBJECTIVE: Severe infections can lead to neuromyopathy in critically ill patients, resulting in limb weakness and difficulty in weaning from a ventilator. This study aims to assess the electrophysiological test results in patients with severe infection and their correlation with severity scores (APACHE II and SOFA). METHODS: Thirty-one patients with severe infection in the EICU were prospectively studied. Factor analysis and principal component regression were applied to develop linear models of electrophysiological diagnostic outcomes with APACHE II and SOFA scores for the entire patient cohort, the younger group (age<55) cohort, and the older group (age>55) cohort of patients with severe infections, respectively...
April 5, 2024: Alternative Therapies in Health and Medicine
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