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https://www.readbyqxmd.com/read/28350576/absence-of-resting-cardiovascular-dysfunction-in-middle-aged-endurance-trained-athletes-with-exaggerated-exercise-blood-pressure-responses
#1
Katharine D Currie, Ryan T Sless, Catherine F Notarius, Scott G Thomas, Jack M Goodman
OBJECTIVE: Untrained individuals with exaggerated blood pressure (EBP) responses to graded exercise testing are characterized as having resting dysfunction of the sympathetic and cardiovascular systems. The purpose of this study was to determine the resting cardiovascular state of endurance-trained individuals with EBP through a comparison of normotensive athletes with and without EBP. METHODS: EBP was defined as a maximal systolic blood pressure (SBP) at least 190 mmHg and at least 210 mmHg for women and men respectively, in response to a graded exercise test...
March 27, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28346898/modelling-of-escherichia-coli-concentrations-in-bathing-water-at-microtidal-coasts
#2
A Palazón, I López, L Aragonés, Y Villacampa, F J Navarro-González
Monitoring of the quality of bathing water in line with the European Commission bathing water directive (Directive 2006/7/EC) is a significant economic expense for those countries with great lengths of coastline. In this study a numerical model based on finite elements is generated whose objective is partially substituting the microbiological analysis of the quality of coastal bathing waters. According to a study of the concentration of Escherichia coli in 299 Spanish Mediterranean beaches, it was established that the most important variables that influence the concentration are: monthly sunshine hours, mean monthly precipitation, number of goat cattle heads, population density, presence of Posidonia oceanica, UV, urbanization level, type of sediment, wastewater treatment ratio, salinity, distance to the nearest discharge, and wave height perpendicular to the coast...
March 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28346426/mrl-proteins-cooperate-with-activated-ras-in-glia-to-drive-distinct-oncogenic-outcomes
#3
E Taylor, N Alqadri, L Dodgson, D Mason, E Lyulcheva, G Messina, D Bennett
The Mig10/RIAM/Lpd (MRL) adapter protein Lpd regulates actin dynamics through interactions with Scar/WAVE and Ena/VASP proteins to promote the formation of cellular protrusions and to stimulate invasive migration. However, the ability of MRL proteins to interact with multiple actin regulators and to promote serum response factor (SRF) signalling has raised the question of whether MRL proteins employ alternative downstream mechanisms to drive oncogenic processes in a context-dependent manner. Here, using a Drosophila model, we show that overexpression of either human Lpd or its Drosophila orthologue Pico can promote growth and invasion of Ras(V12)-induced cell tumours in the brain...
March 27, 2017: Oncogene
https://www.readbyqxmd.com/read/28346324/t-wave-alternans-and-long-qt-syndrome
#4
Rebecca S Isserman, Allan F Simpao, Alan Jay Schwartz, Matthew F Pearsall
No abstract text is available yet for this article.
March 27, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28340715/short-wave-infrared-chemical-imaging-as-future-tool-for-analysing-gunshot-residues-patterns-in-targets
#5
F E Ortega-Ojeda, M Torre-Roldán, C García-Ruiz
This work used chemical imaging in the short-wave infrared region for analysing gunshot residues (GSR) patterns in cotton fabric targets shot with conventional and non-toxic ammunition. It presents a non-destructive, non-toxic, highly visual and hiperspectral-based approach. The method was based on classical least squares regression, and was tested with the ammunition propellants and their standard components' spectra. The propellants' spectra were satisfactorily used (R(2) >0.966, and CorrCoef >0.982) for identifying the GSR irrespective of the type of ammunition used for the shooting...
May 15, 2017: Talanta
https://www.readbyqxmd.com/read/28339242/comment-on-matter-wave-interferometry-of-a-levitated-thermal-nano-oscillator-induced-and-probed-by-a-spin
#6
F Robicheaux
No abstract text is available yet for this article.
March 10, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28339227/cosmic-tsunamis-in-modified-gravity-disruption-of-screening-mechanisms-from-scalar-waves
#7
R Hagala, C Llinares, D F Mota
Extending general relativity by adding extra degrees of freedom is a popular approach for explaining the accelerated expansion of the Universe and to build high energy completions of the theory of gravity. The presence of such new degrees of freedom is, however, tightly constrained from several observations and experiments that aim to test general relativity in a wide range of scales. The viability of a given modified theory of gravity, therefore, strongly depends on the existence of a screening mechanism that suppresses the extra degrees of freedom...
March 10, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28336203/is-extracorporeal-shock-wave-lithotripsy-a-current-treatment-for-urolithiasis-a-systematic-review
#8
P Bahílo Mateu, A Budía Alba, E Liatsikos, M Trassierra Villa, J D López-Acón, D de Guzmán Ordaz, F Boronat Tormo
INTRODUCTION: Technological advances have prompted a change in the management of urolithiasis. Endourological techniques are gaining importance because they are highly effective treatments. The aim of this study was to answer the question of whether extracorporeal shock wave lithotripsy (ESWL) is still a competitive alternative compared with other therapeutic modalities. ACQUISITION OF EVIDENCE: We conducted a literature search of articles published in the past 5 years...
March 20, 2017: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/28336107/enriched-enteral-nutrition-may-improve-short-term-survival-in-stage-iv-gastric-cancer-patients-a-randomized-controlled-trial
#9
Stanislaw Klek, Lucyna Scislo, Elzbieta Walewska, Ryszard Choruz, Aleksander Galas
OBJECTIVE: The aim of the study was to determine whether the postoperative use of enteral nutrition enriched with arginine, glutamine, and omega-3 fatty acids influences survival in patients diagnosed with stomach cancer. For the purpose of the study, the second wave of the trial performed in 2003 to 2009 was done. METHODS: Ninety-nine patients who underwent surgery for gastric cancer (27 F, 72 M, mean age: 62.9 y) met the inclusion criteria. Of those, 54 were randomized to standard and 45 to enriched enteral nutrition (EEN)...
April 2017: Nutrition
https://www.readbyqxmd.com/read/28334662/the-association-between-personality-disorders-with-alcohol-use-and-misuse-a-population-based-twin-study
#10
E C Long, S H Aggen, M C Neale, G P Knudsen, R F Krueger, S C South, N Czajkowski, R Nesvåg, E Ystrom, F A Torvik, K S Kendler, N A Gillespie, T Reichborn-Kjennerud
BACKGROUND: A clearer understanding of the etiological overlap between DSM-IV personality disorders (PDs) and alcohol use (AU) and alcohol use disorder (AUD) is needed. To our knowledge, no study has modeled the association between all 10 DSM-IV PDs and lifetime AU and AUD. The aim of the present study is to identify which PDs are most strongly associated with the phenotypic, genetic, and environmental risks of lifetime AU and AUD, and to determine if these associations are stable across time...
March 7, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28333321/preconception-and-early-pregnancy-maternal-haemodynamic-changes-in-healthy-women-in-relation-to-pregnancy-viability
#11
F L Foo, A Collins, C M McEniery, P R Bennett, I B Wilkinson, C C Lees
STUDY QUESTION: Are there differences in preconception cardiovascular function between women who have a viable pregnancy and those who have a first trimester miscarriage? SUMMARY ANSWER: Preconception cardiovascular function of central haemodynamics and arterial function are similar between women who have a viable pregnancy and those who have a first trimester miscarriage. WHAT IS KNOWN ALREADY: Miscarriages have been associated with increased long-term cardiovascular disease risk, and arterial and cardiovascular dysfunction has been hypothesised as the common link...
March 16, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28332508/prolactin-as-a-predictor-of-endothelial-dysfunction-and-arterial-stiffness-progression-in-menopause
#12
G Georgiopoulos, I Lambrinoudaki, F Athanasouli, E Armeni, A Koliviras, A Augoulea, D Rizos, C Papamichael, A Protogerou, K Stellos, K Stamatelopoulos
Postmenopausal women are at increased risk for progression of arteriosclerosis and hypertension. Recent cross-sectional evidence suggests that high normal circulating prolactin levels may accelerate vascular ageing in menopause. Postmenopausal women (n=201) were consecutively recruited from a Menopause Clinic and re-evaluated in at least one follow-up visit within the next 3 years. Baseline circulating prolactin levels were measured while both baseline and follow-up vascular and biochemical measurements were performed...
March 23, 2017: Journal of Human Hypertension
https://www.readbyqxmd.com/read/28324775/investigation-of-the-ultrasonic-attenuation-in-anisotropic-weld-materials-with-finite-element-modeling-and-grain-scale-material-description
#13
P E Lhuillier, B Chassignole, M Oudaa, S O Kerhervé, F Rupin, T Fouquet
A finite element modeling approach of ultrasonic propagation combined with a description of the microstructure at the scale of the grains has been implemented. The simulations seek to determine the contribution of scattering to the ultrasonic attenuation in polycrystalline materials. The approach is applied to anisotropic microstructures exhibiting both elongated grains and transversely isotropic crystallographic texture which can be found in multipass welds. The ultrasonic propagation is computed with the 2D finite element code ATHENA 2D...
March 8, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28322338/flexible-frequency-selective-metamaterials-for-microwave-applications
#14
Bo Gao, Matthew M F Yuen, Terry Tao Ye
Metamaterials have attracted more and more research attentions recently. Metamaterials for electromagnetic applications consist of sub-wavelength structures designed to exhibit particular responses to an incident EM (electromagnetic) wave. Traditional EM (electromagnetic) metamaterial is constructed from thick and rigid structures, with the form-factor suitable for applications only in higher frequencies (above GHz) in microwave band. In this paper, we developed a thin and flexible metamaterial structure with small-scale unit cell that gives EM metamaterials far greater flexibility in numerous applications...
March 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28320462/varying-the-item-format-improved-the-range-of-measurement-in-patient-reported-outcome-measures-assessing-physical-function
#15
Gregor Liegl, Barbara Gandek, H Felix Fischer, Jakob B Bjorner, John E Ware, Matthias Rose, James F Fries, Sandra Nolte
BACKGROUND: Physical function (PF) is a core patient-reported outcome domain in clinical trials in rheumatic diseases. Frequently used PF measures have ceiling effects, leading to large sample size requirements and low sensitivity to change. In most of these instruments, the response category that indicates the highest PF level is the statement that one is able to perform a given physical activity without any limitations or difficulty. This study investigates whether using an item format with an extended response scale, allowing respondents to state that the performance of an activity is easy or very easy, increases the range of precise measurement of self-reported PF...
March 21, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28319298/diversity-in-gold-finger-structure-elucidated-by-traveling-wave-ion-mobility-mass-spectrometry
#16
Zhifeng Du, Raphael E F de Paiva, Kristina Nelson, Nicholas P Farrell
Traveling wave ion mobility (TWIM) mass spectrometry (MS) is a powerful method for the structural and conformational analysis of proteins and peptides, enabling the differentiation of isomeric peptides (or proteins) that have the same sequence but are modified at different residues. In this study, the TWIM-MS technique was used to separate isomeric Au(I) metallopeptide ions that were formed by Zn(II) displacement from the parent zinc fingers (ZFs). The synthetic gold finger peptides were derived from the C-terminus of the HIV nucleocapsid p7 protein (NCp7-F2) and finger 3 of the Sp1 transcription factor (Sp1-F3)...
March 20, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28317163/the-value-of-diastolic-flow-reversal-in-the-descending-thoracic-aorta-as-a-determinant-of-invasively-measured-aortic-pulse-pressure
#17
Hack-Lyoung Kim, Yu Nui Kim, Hee-Jun Kim, Woo-Hyun Lim, Jae-Bin Seo, Sang-Hyun Kim, Myung-A Kim, Joo-Hee Zo
AIM: Although the diastolic flow reversal of the descending aorta has been recognized in patients with aortic regurgitation, its generation without this condition is still unknown. This study was performed to investigate whether flow patterns of the descending thoracic aorta, as measured by echocardiography, can represent invasively measured aortic pulse pressure (APP). METHODS: A total of 100 patients (age, 62.3±11.0 years; men, 62.0%) undergoing invasive coronary angiography (ICA) was analyzed...
March 19, 2017: Echocardiography
https://www.readbyqxmd.com/read/28314742/acute-changes-in-left-atrial-pressure-after-mitraclip-are-associated-with-improvement-in-6-minute-walk-distance
#18
Elad Maor, Claire E Raphael, Sidakpal S Panaich, Guy S Reeder, Rick A Nishimura, Vuyisile T Nkomo, Charanjit S Rihal, Mackram F Eleid
BACKGROUND: Data on the clinical use of left atrial (LA) hemodynamic monitoring during MitraClip procedure are limited. This study evaluated the association between intraprocedural changes in LA pressure after MitraClip and improvement in exercise capacity as documented by 6-minute walk test (6MWT). METHODS AND RESULTS: Study population included 50 patients who underwent MitraClip at the Mayo Clinic (Rochester, MN), between June 2014 and July 2016 and completed both baseline and 30-day follow-up 6MWT...
April 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28297938/extracting-trajectory-equations-of-classical-periodic-orbits-from-the-quantum-eigenmodes-in-two-dimensional-integrable-billiards
#19
Y H Hsieh, Y T Yu, P H Tuan, J C Tung, K F Huang, Y F Chen
The trajectory equations for classical periodic orbits in the equilateral-triangular and circular billiards are systematically extracted from quantum stationary coherent states. The relationship between the phase factors of quantum stationary coherent states and the initial positions of classical periodic orbits is analytically derived. In addition, the stationary coherent states with noncoprime parametric numbers are shown to correspond to the multiple periodic orbits, which cannot be explicable in the one-particle picture...
February 2017: Physical Review. E
https://www.readbyqxmd.com/read/28297918/energy-partition-scale-by-scale-in-magnetic-archimedes-coriolis-weak-wave-turbulence
#20
A Salhi, F S Baklouti, F Godeferd, T Lehner, C Cambon
Magnetic Archimedes Coriolis (MAC) waves are omnipresent in several geophysical and astrophysical flows such as the solar tachocline. In the present study, we use linear spectral theory (LST) and investigate the energy partition, scale by scale, in MAC weak wave turbulence for a Boussinesq fluid. At the scale k^{-1}, the maximal frequencies of magnetic (Alfvén) waves, gravity (Archimedes) waves, and inertial (Coriolis) waves are, respectively, V_{A}k,N, and f. By using the induction potential scalar, which is a Lagrangian invariant for a diffusionless Boussinesq fluid [Salhi et al...
February 2017: Physical Review. E
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