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Piotr Kukla, Dariusz A Kosior, Andrzej Tomaszewski, Katarzyna Ptaszyńska-Kopczyńska, Katarzyna Widejko, Robert Długopolski, Andrzej Skrzyński, Piotr Błaszczak, Kamil Fijorek, Marcin Kurzyna
BACKGROUND: Electrocardiography (ECG) is still one of the first tests performed at admission, mostly in patients (pts) with chest pain or dyspnea. The aim of this study was to assess the correlation between electrocardiographic abnormalities and cardiac biomarkers as well as echocardiographic parameter in patients with acute pulmonary embolism. METHODS: We performed a retrospective analysis of 614 pts. (F/M 334/280; mean age of 67.9 ± 16.6 years) with confirmed acute pulmonary embolism (APE) who were enrolled to the ZATPOL-2 Registry between 2012 and 2014...
February 18, 2017: Annals of Noninvasive Electrocardiology
Bohan Wang, Hongxiu Ning, Amanda B Reed-Maldonado, Jun Zhou, Yajun Ruan, Tie Zhou, Hsun Shuan Wang, Byung Seok Oh, Lia Banie, Guiting Lin, Tom F Lue
Low-intensity extracorporeal shock wave therapy (Li-ESWT) is used in the treatment of erectile dysfunction, but its mechanisms are not well understood. Previously, we found that Li-ESWT increased the expression of brain-derived neurotrophic factor (BDNF). Here we assessed the underlying signaling pathways in Schwann cells in vitro and in penis tissue in vivo after nerve injury. The result indicated that BDNF were significantly increased by the Li-ESWT after nerve injury, as well as the expression of BDNF in Schwann cells (SCs, RT4-D6P2T) in vitro...
February 16, 2017: International Journal of Molecular Sciences
Vladimir Zhdankin, Gregory R Werner, Dmitri A Uzdensky, Mitchell C Begelman
We present results from particle-in-cell simulations of driven turbulence in magnetized, collisionless, and relativistic pair plasmas. We find that the fluctuations are consistent with the classical k_{⊥}^{-5/3} magnetic energy spectrum at fluid scales and a steeper k_{⊥}^{-4} spectrum at sub-Larmor scales, where k_{⊥} is the wave vector perpendicular to the mean field. We demonstrate the development of a nonthermal, power-law particle energy distribution f(E)∼E^{-α}, with an index α that decreases with increasing magnetization and increases with an increasing system size (relative to the characteristic Larmor radius)...
February 3, 2017: Physical Review Letters
A Martinelli, P Manfrinetti, A Provino, A Genovese, F Caglieris, G Lamura, C Ritter, M Putti
In this Letter we report high-resolution synchrotron x-ray powder diffraction and transmission electron microscope analysis of Mn-substituted LaFeAsO samples, demonstrating that a static incommensurate modulated structure develops across the low-temperature orthorhombic phase, whose modulation wave vector depends on the Mn content. The incommensurate structural distortion is likely originating from a charge-density-wave instability, a periodic modulation of the density of conduction electrons associated with a modulation of the atomic positions...
February 3, 2017: Physical Review Letters
Fernanda Zucki, Thais C Morata, Josilene L Duarte, Maria Cecília F Ferreira, Manoel H Salgado, Kátia F Alvarenga
INTRODUCTION: The literature has reported the association between lead and auditory effects, based on clinical and experimental studies. However, there is no consensus regarding the effects of lead in the auditory system, or its correlation with the concentration of the metal in the blood. OBJECTIVE: To investigate the maturation state of the auditory system, specifically the auditory nerve and brainstem, in rats exposed to lead acetate and supplemented with ferrous sulfate...
January 23, 2017: Brazilian Journal of Otorhinolaryngology
S Bellissima, M Neumann, E Guarini, U Bafile, F Barocchi
Extending a preceding study of the velocity autocorrelation function (VAF) in a simulated Lennard-Jones fluid [Phys. Rev. E 92, 042166 (2015)PLEEE81539-375510.1103/PhysRevE.92.042166] to cover higher-density and lower-temperature states, we show that the recently demonstrated multiexponential expansion method allows for a full account and understanding of the basic dynamical processes encompassed by a fundamental quantity as the VAF. In particular, besides obtaining evidence of a persisting long-time tail, we assign specific and unambiguous physical meanings to groups of exponential modes related to the longitudinal and transverse collective dynamics, respectively...
January 2017: Physical Review. E
Tommy Dessup, Christophe Coste, Michel Saint Jean
We study the path toward equilibrium of pairs of solitary wave envelopes (bubbles) that modulate a regular zigzag pattern in an annular channel. We evidence that bubble pairs are metastable states, which spontaneously evolve toward a stable single bubble. We exhibit the concept of topological frustration of a bubble pair. A configuration is frustrated when the particles between the two bubbles are not organized in a modulated staggered row. For a nonfrustrated (NF) bubble pair configuration, the bubbles interaction is attractive, whereas it is repulsive for a frustrated (F) configuration...
January 2017: Physical Review. E
E Guarini, S Bellissima, U Bafile, E Farhi, A De Francesco, F Formisano, F Barocchi
We show that by exploiting multi-Lorentzian fits of the self-dynamic structure factor at various wave vectors it is possible to carefully perform the Q→0 extrapolation required to determine the spectrum Z(ω) of the velocity autocorrelation function of a liquid. The smooth Q dependence of the fit parameters makes their extrapolation to Q=0 a simple procedure from which Z(ω) becomes computable, with the great advantage of solving the problems related to resolution broadening of either experimental or simulated self-spectra...
January 2017: Physical Review. E
N Ratan, N J Sircombe, L Ceurvorst, J Sadler, M F Kasim, J Holloway, M C Levy, R Trines, R Bingham, P A Norreys
Here we investigate, using relativistic fluid theory and Vlasov-Maxwell simulations, the local heating of a dense plasma by two crossing electron beams. Heating occurs as an instability of the electron beams drives Langmuir waves, which couple nonlinearly into damped ion-acoustic waves. Simulations show a factor 2.8 increase in electron kinetic energy with a coupling efficiency of 18%. Our results support applications to the production of warm dense matter and as a driver for inertial fusion plasmas.
January 2017: Physical Review. E
Fabio A Schaberle, Artur R Abreu, Nuno P F Gonçalves, Gonçalo F F Sá, Mariette M Pereira, Luís G Arnaut
Manganese(III) and manganese(II) complexes of halogenated sulfonamide tetraphenylbacteriochlorins were prepared for the first time via a transmetalation reaction and shown to be stable at room temperature. The behavior of the electronic states of the paramagnetic complexes is remarkably different from those of the metal-free bacteriochlorins or diamagnetic metallobacteriochlorins. The Mn(3+) complex exhibits eight electronic transitions between different states from 300 to 1100 nm, with a very prominent band (molar absorption coefficient of ca...
February 16, 2017: Inorganic Chemistry
Luigi F Agnati, Manuela Marcoli, Giuseppina Leo, Guido Maura, Diego Guidolin
In this review, the aspects and further developments of the concept of homeostasis are discussed also in the perspective of their possible impact in the clinical practice, particularly as far as psychic homeostasis is concerned. A brief historical survey and comments on the concept of homeostasis and allostasis are presented to introduce our proposal that is based on the classical assumption of the interstitial fluid (ISF) as the internal medium for multicellular organisms. However, the new concept of a hierarchic role of ISF of the various organs is introduced...
February 3, 2017: International Journal of Molecular Medicine
Pavel Drábek, Peter Takáč
We consider a one-dimensional population genetics model for the advance of an advantageous gene. The model is described by the semilinear Fisher equation with unbalanced bistable non-Lipschitzian nonlinearity f(u). The "nonsmoothness" of f allows for the appearance of travelling waves with a new, more realistic profile. We study existence, uniqueness, and long-time asymptotic behavior of the solutions u(x, t), [Formula: see text]. We prove also the existence and uniqueness (up to a spatial shift) of a travelling wave U...
February 14, 2017: Journal of Mathematical Biology
Santosh Kumar Sinha, Kush Bhagat, Mohammad Asif, Karandeep Singh, Mohit Sachan, Vikas Mishra, Nasar Afdaali, Mukesh Jitendra Jha, Ashutosh Kumar, Shravan Singh, Rupesh Sinha, Dibbendhu Khanra, Ramesh Thakur, Chandra Mohan Varma, Vinay Krishna, Umeshwar Pandey
BACKGROUND: Left ventricular (LV) dyssynchrony frequently occurs in patients with heart failure (HF). QRS ≥ 120 ms is a surrogate marker of electrical dyssynchrony, which occurs in only 30% of HF patients. In contrary, in those with normal QRS (nQRS) duration, LV dyssynchrony has been reported in 20-50%. This study was carried out to investigate the role of fragmented QRS (fQRS) on the surface electrocardiography (ECG) as a marker of electrical dyssynchrony to predict the presence of significant intraventricular dyssynchrony (IVD) by subsequent echocardiographic assessment...
August 2016: Cardiology Research
H M T Boer, S T Butler, C Stötzel, M F W Te Pas, R F Veerkamp, H Woelders
A recently developed mechanistic mathematical model of the bovine estrous cycle was parameterized to fit empirical data sets collected during one estrous cycle of 31 individual cows, with the main objective to further validate the model. The a priori criteria for validation were (1) the resulting model can simulate the measured data correctly (i.e. goodness of fit), and (2) this is achieved without needing extreme, probably non-physiological parameter values. We used a least squares optimization procedure to identify parameter configurations for the mathematical model to fit the empirical in vivo measurements of follicle and corpus luteum sizes, and the plasma concentrations of progesterone, estradiol, FSH and LH for each cow...
February 15, 2017: Animal: An International Journal of Animal Bioscience
Yi Dong, Roxana Sirli, Giovanna Ferraioli, Ioan Sporea, Liliana Chiorean, Xinwu Cui, Mei Fan, Wen-Ping Wang, Odd Helge Gilja, Paul S Sidhu, Christoph F Dietrich
Shear wave elastography (SWE) has been developed to non-invasively estimate liver stiffness. Different techniques are available and they are described in detail in the EFSUMB guidelines on elastography. However, there are only a few published studies investigating normal ranges in healthy subjects by comparing different equipment and analysing influencing factors. In the present review, we summarize the impact factors on liver stiffness measurement (LSM) using SWE, report its reproducibility, and define normal range tables of LSM in healthy subjects for clinical practice according to the published literature...
February 2017: Zeitschrift Für Gastroenterologie
Donghwi Park, Jin-Sung Park
Amyotrophic lateral sclerosis (ALS) has a peculiar involvement pattern; clinically it is known as split hand syndrome and electrophysiologically shows abnormalities in the abductor pollicis brevis (APB)/abductor digiti minimi (ADM) ratio. The aim of this study was to find a significant electrophysiological parameter in upper limb onset ALS patients with normal APB/ADM ratio when compared to cervical spondylotic amyotrophy (CSA) and healthy controls. We retrospectively reviewed the electrophysiological results of 47 upper limb onset ALS and 42 CSA cases; 20 healthy individuals were included as controls...
February 10, 2017: Neurological Sciences
F Gustave, N Radwell, C McIntyre, J P Toomey, D M Kane, S Barland, W J Firth, G-L Oppo, T Ackemann
A stable nonlinear wave packet, self-localized in all three dimensions, is an intriguing and much sought after object in nonlinear science in general and in nonlinear photonics in particular. We report on the experimental observation of mode-locked spatial laser solitons in a vertical-cavity surface-emitting laser with frequency-selective feedback from an external cavity. These spontaneously emerging and long-term stable spatiotemporal structures have a pulse length shorter than the cavity round-trip time and may pave the way to completely independent cavity light bullets...
January 27, 2017: Physical Review Letters
James E Ip, Michael S Wu, Peter J Kennel, George Thomas, Christopher F Liu, Jim W Cheung, Steven M Markowitz, Bruce B Lerman
INTRODUCTION: The subcutaneous implantable cardioverter defibrillator (ICD) has emerged as a viable therapeutic option for patients who are deemed high risk for sudden cardiac death. Previous studies have shown that 7-15% of patients are not candidates for the S-ICD based on their intrinsic QRS/T-wave morphology. Presently, it is not known if the S-ICD can be considered as supplementary therapy in patients who are ventricularly paced. We sought to determine the proportion of ventricularly paced patients who would qualify for an S-ICD...
February 10, 2017: Journal of Cardiovascular Electrophysiology
Satoshi Nagase, Masamichi Tanaka, Hiroshi Morita, Koji Nakagawa, Tadashi Wada, Masato Murakami, Nobuhiro Nishii, Kazufumi Nakamura, Hiroshi Ito, Tohru Ohe, Kengo F Kusano
Background: Brugada syndrome (BrS) is characterized by J-point or ST-segment elevation on electrocardiograms (ECGs) and increased risk of ventricular fibrillation (VF). In BrS, epicardial depolarization abnormality with delayed potential on the right ventricular outflow tract is reportedly the predominant mechanism underlying VF. Yet VF occurrence is also associated with early repolarization (ER) pattern in the inferolateral ECG leads, which may represent the inferior and/or left lateral ventricular myocardium...
2017: Frontiers in Physiology
Yuki Fukumoto, Yoshibumi Bunno, Toshiaki Suzuki
[Purpose] This study aimed to examine the effect of motor imagery on the accuracy of motion and the excitability of spinal neural function. [Subjects and Methods] Thirty healthy volunteers (males, 15; females, 15; mean age, 20.3 ± 1.0 years) were recruited. F-waves was recorded at rest, while holding a sensor, and while using motor imagery. Next, subjects learned 50% maximum voluntary contraction. The pinch force was measured without visual feedback before and after motor imagery. F-waves were analyzed with respect to persistence and the F/M amplitude ratio...
December 2016: Journal of Physical Therapy Science
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