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https://www.readbyqxmd.com/read/29441457/effect-of-vsl-3-probiotic-in-a-patient-with-glycogen-storage-disease-type-ia-and-irritable-bowel-disease-like-disease
#1
Miguel Carnero-Gregorio, Alberto Molares-Vila, Alberte Corbalán-Rivas, Carlos Villaverde-Taboada, Carmen Rodríguez-Cerdeira
Gut Inflammatory bowel disease (IBD) is a group of chronic gastrointestinal disorders characterised by relapsing and remitting inflammation of the gastrointestinal tract. The two most common types of IBDs are ulcerative colitis and Crohn's disease. Patients with glycogen storage disease (GSD) type Ia present with gastrointestinal symptoms such as recurrent abdominal pain, bloating and changes in stool form or frequency, which is clinically difficult to distinguish from IBD. We report the case of a 36-year-old man with GSD type Ia and IBD-like disease...
February 13, 2018: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29424814/cytomegalovirus-infection-in-pediatric-severe-ulcerative-colitis-a-multicenter-study-from-the-pediatric-inflammatory-bowel-disease-porto-group-of-the-european-society-of-pediatric-gastroenterology-hepatology-and-nutrition
#2
Shlomi Cohen, Christine Martinez-Vinson, Marina Aloi, Dan Turner, Amit Assa, Lissy de Ridder, Victorien M Wolters, Tim de Meij, Patrizia Alvisi, Jiri Bronsky, Uri Kopylov
BACKGROUND: Data on the clinical course and outcomes of pediatric patients with cytomegalovirus (CMV) infection complicating acute severe ulcerative colitis (ASC) are very limited. The aim of our study was to compare outcomes of children with ASC who were CMV positive or CMV negative. METHODS: This was a multicenter retrospective case-controlled study, from centers affiliated with the Pediatric Inflammatory Bowel Disease Porto Group of European Society of Pediatric Gastroenterology, Hepatology, and Nutrition...
March 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29423389/food-elimination-diet-and-nutritional-deficiency-in-patients-with-inflammatory-bowel-disease
#3
Hee-Sook Lim, Soon-Kyung Kim, Su-Jin Hong
Certain types of foods are common trigger for bowel symptoms such as abdominal discomfort or pain in patients with inflammatory bowel disease (IBD). But indiscriminate food exclusions from their diet can lead extensive nutritional deficiencies. The aim of this study was to investigate nutritional status, food restriction and nutrient intake status in IBD patients. A total 104 patients (food exclusion group: n = 49; food non-exclusion group: n = 55) participated in the survey. The contents were examined by 3 categories: 1) anthropometric and nutritional status; 2) diet beliefs and food restriction; and 3) nutrient intake...
January 2018: Clinical Nutrition Research
https://www.readbyqxmd.com/read/29413010/nutritional-interventions-in-the-patient-with-inflammatory-bowel-disease
#4
REVIEW
Berkeley N Limketkai, Andrea Wolf, Alyssa M Parian
Nutritional strategies have been explored as primary or adjunct therapies for inflammatory bowel disease (IBD). Exclusive enteral nutrition is effective for the induction of remission in Crohn disease and is recommended as a first-line therapy for children. Dietary strategies focus on adjusting the ratio of consumed nutrients that are proinflammatory or antiinflammatory. Treatments with dietary supplements focus on the antiinflammatory effects of the individual supplements (eg, curcumin, omega-3 fatty acids, vitamin D) or their positive effects on the intestinal microbiome (eg, prebiotics, probiotics)...
March 2018: Gastroenterology Clinics of North America
https://www.readbyqxmd.com/read/29408835/incidence-and-factors-correlating-with-incisional-hernia-following-open-bowel-resection-in-patients-with-inflammatory-bowel-disease-a-review-of-1000-patients
#5
Tomas M Heimann, Santosh Swaminathan, Adrian J Greenstein, Randolph M Steinhagen
OBJECTIVE: The aim of this study was to identify the incidence and factors associated with the development of incisional hernia (IH) in patients with inflammatory bowel disease (IBD) undergoing open bowel resections. BACKGROUND: Predisposing factors for IH have not been well studied in patients with IBD undergoing open bowel resection. The role of duration of the disease, nutritional factors, anti-inflammatory treatment, previous operative procedures, wound infection, and other complicating factors remains unclear...
March 2018: Annals of Surgery
https://www.readbyqxmd.com/read/29389238/inflammatory-diseases-of-the-gut
#6
Michael Rohr, Chandrakala Aluganti Narasimhulu, Dhara Sharma, Mitsushita Doomra, Aladdin Riad, Saleh Naser, Sampath Parthasarathy
Inflammatory bowel diseases (IBD), including Crohn's disease and ulcerative colitis, are chronic inflammatory disorders of the gastrointestinal tract whose prevalence has been dramatically increasing over the past decade. New studies have shown that IBD is the second most common chronic inflammatory disease worldwide after rheumatoid arthritis, affecting millions of people mainly in industrialized countries. Symptoms of IBD include frequent bloody diarrhea, abdominal cramping, anorexia, abdominal distension, and emesis...
February 1, 2018: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29384890/nutrition-in-paediatric-inflammatory-bowel-disease-a-position-paper-on-behalf-of-the-porto-ibd-group-of-espghan
#7
Erasmo Miele, Raanan Shamir, Marina Aloi, Amit Assa, Christian Braegger, Jiri Bronsky, Lissy de Ridder, Johanna C Escher, Iva Hojsak, Sanja Kolaček, Sibylle Koletzko, Arie Levine, Paolo Lionetti, Massimo Martinelli, Frank Ruemmele, Richard K Russell, Rotem Sigall Boneh, Johan van Limbergen, Gigi Veereman, Annamaria Staiano
BACKGROUND AND AIMS: A growing body of evidence supports the need for detailed attention to nutrition and diet in children with IBD. We aimed to define the steps in instituting dietary or nutritional management in light of the current evidence and to offer a useful and practical guide to physicians and dieticians involved in the care of paediatric IBD patients. METHODS: A group of 20 experts in paediatric IBD participated in an iterative consensus process including 2 face-to-face meetings, following an open call to ESPGHAN Porto, IBD Interest and Nutrition Committee...
January 29, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29337777/rescue-diverting-loop-ileostomy-an-alternative-to-emergent-colectomy-in-the-setting-of-severe-acute-refractory-ibd-colitis
#8
Tara A Russell, Aaron J Dawes, Danielle S Graham, Stephanie A K Angarita, Christina Ha, Jonathan Sack
BACKGROUND: Severe acute refractory colitis has traditionally been an indication for emergent colectomy in IBD, yet under these circumstances patients are at elevated risk for complications because of their heightened inflammatory state, nutritional deficiencies, and immunocompromised state. OBJECTIVE: We hypothesized that rescue diverting loop ileostomy may be a viable alternative to emergent colectomy, providing the opportunity for colonic healing and patient optimization before more definitive surgery...
February 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29328869/inflammatory-bowel-diseases-and-fermentable-oligosaccharides-disaccharides-monosaccharides-and-polyols-an-overview
#9
Sandra Maria Barbalho, Ricardo de Alvares Goulart, Ana Luíza de Carvalho Aranão, Pamela Grazielle Correa de Oliveira
Inflammatory bowel diseases (IBDs) are mainly represented by ulcerative colitis and Crohn's disease, and the increase in the incidence tends to follow the rapid industrialization and lifestyle of modern societies. FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides, and polyols) consist of molecules that are poorly absorbed in the small intestine and are fermented by bacteria in the colon leading to symptoms such as bloating, flatulence, diarrhea, and abdominal pain. Reduction of the ingestion of FODMAP could reduce the symptoms and improve the quality of life...
January 12, 2018: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29324477/assuring-quality-for-non-hospital-based-biologic-infusions-in-pediatric-inflammatory-bowel-disease-a-clinical-report-from-the-north-american-society-for-pediatric-gastroenterology-hepatology-and-nutrition
#10
Elaine Barfield, Robbyn Sockolow, Edward Hoffenberg, Shehzad Saeed, Sandra Kim, Leah Siebold, Joseph Picoraro, Jonathan Moses, Dana Dykes, Andrew Grossman, Ghassan Wahbeh, K T Park
The primary aim of this Clinical Report by the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition is to provide formal guidance to pediatric gastroenterologists and clinicians, health systems, and insurance payers regarding home- and office-based infusions for biologic therapies in pediatric inflammatory bowel disease (IBD). Patients in North America are increasingly denied coverage by payers based on "place of service" codes at hospital-based infusion units where the treating clinicians primarily provide care...
January 10, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29313266/factors-that-influence-treatment-and-non-treatment-decision-making-among-individuals-with-inflammatory-bowel-disease-an-integrative-review
#11
REVIEW
Kendra J Kamp, Kelly Brittain
Inflammatory bowel disease (IBD) is a chronic illness with periods of varying disease activity called flares and remissions. Since IBD impacts quality of life, patients make IBD disease management decisions every day. Previous research indicates limited insight about factors that influence decisions regarding disease management and the types of decisions IBD patients make. The purpose of this integrative review is to identify types of treatment and non-treatment decisions and the factors that influence decision making regarding disease management among individuals with IBD...
January 8, 2018: Patient
https://www.readbyqxmd.com/read/29285689/gut-microbiota-in-the-pathogenesis-of-inflammatory-bowel-disease
#12
REVIEW
Atsushi Nishida, Ryo Inoue, Osamu Inatomi, Shigeki Bamba, Yuji Naito, Akira Andoh
Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, is a chronic and relapsing inflammatory disorder of the intestine. Although its incidence is increasing globally, the precise etiology remains unclear and a cure for IBD has yet to be discovered. The most accepted hypothesis of IBD pathogenesis is that complex interactions between genetics, environmental factors, and the host immune system lead to aberrant immune responses and chronic intestinal inflammation. The human gut harbors a complex and abundant aggregation of microbes, collectively referred to as the gut microbiota...
December 29, 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/29282618/hair-mineral-and-trace-element-contents-as-reliable-markers-of-nutritional-status-compared-to-serum-levels-of-these-elements-in-children-newly-diagnosed-with-inflammatory-bowel-disease
#13
Jin Min Cho, Hye Ran Yang
Patients with inflammatory bowel disease (IBD) are at high risk for nutritional deficiencies because of long-term inflammation in the gut mucosa and decreased oral intake. Because inflammation responses affect serum micronutrient concentrations, serum levels are limited in reflecting body nutrient status in acute and chronic illness. We investigated the usefulness of measuring trace elements in hair as reliable markers of nutritional status compared to serum levels in children with IBD. We retrospectively analyzed pediatric patients newly diagnosed with Crohn's disease (n = 49) and ulcerative colitis (n = 16) and controls (n = 29) from 2012 to 2016...
December 27, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/29216349/developing-a-standard-set-of-patient-centred-outcomes-for-inflammatory-bowel-disease-an-international-cross-disciplinary-consensus
#14
Andrew H Kim, Charlotte Roberts, Brian G Feagan, Rupa Banerjee, Willem Bemelman, Keith Bodger, Marc Derieppe, Axel Dignass, Richard Driscoll, Ray Fitzpatrick, Janette Gaarentstroom-Lunt, Peter D Higgins, Paulo Gustavo Kotze, Jillian Meissner, Marian O'Connor, Zhi-Hua Ran, Corey A Siegel, Helen Terry, Welmoed K van Deen, C Janneke van der Woude, Alandra Weaver, Suk-Kyun Yang, Bruce E Sands, Séverine Vermeire, Simon Pl Travis
Background and Aims: Success in delivering value-based healthcare involves measuring outcomes that matter most to patients. Our aim was to develop a minimum Standard Set of patient-centred outcome measures for inflammatory bowel disease (IBD), for use in different healthcare settings. Methods: An international working group (n=25) representing patients, patient associations, gastroenterologists, surgeons, specialist nurses, IBD registries and patient-reported outcome measure (PROM) methodologists participated in a series of teleconferences incorporating a modified Delphi process...
December 5, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/29210919/the-role-of-combination-therapy-in-pediatric-inflammatory-bowel-disease-a-clinical-report-from-the-north-american-society-for-pediatric-gastroenterology-hepatology-and-nutrition
#15
Andrew S Day, Ajay S Gulati, Nishaben Patel, Brendan Boyle, K T Park, Shehzad A Saeed
The treatment goal for children suffering from inflammatory bowel disease has been evolving with biologic therapies like anti-tumor necrosis factor agents assuming a more central role in treatment of more aggressive and extensive phenotype. Earlier introduction of anti-tumor necrosis factor agents have shown to be more effective and may even alter the natural history of inflammatory bowel disease. Development of anti-drug antibodies, however, limits long-term usage and leads to dose adjustment in almost half of patients treated with these medications...
February 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29173522/vitamins-and-minerals-in-inflammatory-bowel-disease
#16
REVIEW
Fayez K Ghishan, Pawel R Kiela
Indiscriminate use of multivitamin/mineral supplements in the general population may be misguided, but patients with chronic Inflammatory Bowel Diseases (IBD) should be monitored and compensated for nutritional deficiencies. Mechanistic links between vitamin/mineral deficiencies and IBD pathology has been found for some micronutrients and normalizing their levels is clinically beneficial. Others, like vitamin A, although instinctively desirable, produced disappointing results. Restoring normal levels of the selected micronutrients requires elevated doses to compensate for defects in absorptive or signaling mechanisms...
December 2017: Gastroenterology Clinics of North America
https://www.readbyqxmd.com/read/29173519/diet-as-a-therapeutic-option-for-adult-inflammatory-bowel-disease
#17
REVIEW
Samir Kakodkar, Ece A Mutlu
There are many mechanisms to explain how food may drive and ameliorate inflammation. Although there are no consistent macronutrient associations inflammatory bowel disease (IBD) development, many exclusion diets have been described: IgG-4 guided exclusion diet; semivegetarian diet; low-fat, fiber-limited exclusion diet; Paleolithic diet; Maker's diet; vegan diet; Life without Bread diet; exclusive enteral nutrition (EEN), the Specific Carbohydrate Diet (SCD) and the low FODMAP diet. The literature on diet and IBD is reviewed with a particular focus on EEN, SCD, and low FODMAP diets...
December 2017: Gastroenterology Clinics of North America
https://www.readbyqxmd.com/read/29173518/dietary-therapies-in-pediatric-inflammatory-bowel-disease-an-evolving-inflammatory-bowel-disease-paradigm
#18
REVIEW
Erin R Lane, Dale Lee, David L Suskind
Nutrition has long been recognized as a critical component in the treatment of pediatric inflammatory bowel disease (IBD). Formerly, nutritional interventions have focused on targeting improved weight gain and linear growth, as well as correction of micronutrient deficiencies. Recently, there has been growing interest and study of dietary interventions for induction and maintenance of remission. In addition to exclusive enteral nutrition, successes have been achieved with specific exclusion diets. This article evaluates current literature regarding the role of diet and nutrition in pathogenesis of disease, as well as the role of diet as primary therapy for pediatric IBD...
December 2017: Gastroenterology Clinics of North America
https://www.readbyqxmd.com/read/29163522/the-vagus-nerve-in-the-neuro-immune-axis-implications-in-the-pathology-of-the-gastrointestinal-tract
#19
REVIEW
Bruno Bonaz, Valérie Sinniger, Sonia Pellissier
The vagus nerve (VN) is the longest nerve of the organism and a major component of the parasympathetic nervous system which constitutes the autonomic nervous system (ANS), with the sympathetic nervous system. There is classically an equilibrium between the sympathetic and parasympathetic nervous systems which is responsible for the maintenance of homeostasis. An imbalance of the ANS is observed in various pathologic conditions. The VN, a mixed nerve with 4/5 afferent and 1/5 efferent fibers, is a key component of the neuro-immune and brain-gut axes through a bidirectional communication between the brain and the gastrointestinal (GI) tract...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29155253/the-association-of-inflammatory-bowel-disease-and-immediate-postoperative-outcomes-following-lumbar-fusion
#20
Joseph E Tanenbaum, Stephanie T Kha, Edward C Benzel, Michael P Steinmetz, Thomas E Mroz
BACKGROUND CONTEXT: The United States Centers for Disease Control estimates the prevalence of inflammatory bowel disease (IBD) at over 3.1 million people. As diagnostic techniques and treatment options for IBD improve, the prevalence of IBD is expected to increase. For spine surgeons, patients with IBD have a unique complication profile because IBD patients may present with poor nutritional status and because the medications used to manage IBD have been associated with poor vertebral bone mineralization and immunosuppression...
November 15, 2017: Spine Journal: Official Journal of the North American Spine Society
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