keyword
https://read.qxmd.com/read/37307318/appraising-jackson-based-unrestorability-to-competence-to-stand-trial-the-demonstration-model
#21
JOURNAL ARTICLE
Kirk Heilbrun, Christy Giallella, H Jean Wright, David DeMatteo, Patricia A Griffin, Neil Gowensmith, Benjamin Locklair, David Ayers, Alisha Desai, Victoria Pietruszka
Under United States law, criminal prosecution may not proceed against a defendant who is incompetent to participate in this process. The vast majority of defendants who are adjudicated incompetent to stand trial (IST) will subsequently regain sufficient capacities to be adjudicated competent to stand trial (CST). However, a small subgroup of defendants do not show sufficient improvement in clinical functioning and functional-legal capacities to regain CST. Under Jackson v. Indiana (1972), such individuals should be adjudicated unrestorably IST, with associated actions (e...
June 12, 2023: Psychological Services
https://read.qxmd.com/read/37210426/regulatory-aspects-of-a-nanomaterial-for-imaging-therapeutic-cells
#22
JOURNAL ARTICLE
Margriet van der Zee, Claudette de Vries, Marc Masa, Marta Morales, Marta Rayo, Ingrid Hegger
The ability to track therapeutic cells upon administration to the patient is of interest to both regulators and developers of cell therapy. The European Commission Horizon2020 project nTRACK from 2017-2022 aimed to develop a multi-modal nano-imaging agent to track therapeutic cells during development of a cell therapy. As part of this project, we investigated the regulatory pathway involved for such a product if marketed as a stand-alone product. An important regulatory hurdle appeared to be the appropriate regulatory classification of the nTRACK nano-imaging agent, as neither the definition for medicinal product nor the definition for medical device appeared to be a good fit for the purpose of the product and we were confronted with diverging views of competent authorities on the classification...
May 20, 2023: Drug Delivery and Translational Research
https://read.qxmd.com/read/37162478/effectiveness-of-patient-education-as-a-stand-alone-intervention-for-patients-with-chronic-widespread-pain-and-fibromyalgia-a-systematic-review-and-meta-analysis-of-randomized-trials
#23
JOURNAL ARTICLE
P H Duhn, E E Wæhrens, M B Pedersen, S M Nielsen, H Locht, H Bliddal, R Christensen, K Amris
OBJECTIVE: Patient education is recommended as an integral component of the therapeutic plan for the management of chronic widespread pain (CWP) and fibromyalgia (FM). The key purpose of patient education is to increase the patient's competence to manage his or her own health requirements, encouraging self-management and a return to desired everyday activities and lifestyle. The aim of this systematic review was to evaluate the evidence for the benefits and potential harms associated with the use of patient education as a stand-alone intervention for individuals with CWP and FM through randomized controlled trials (RCTs)...
May 10, 2023: Scandinavian Journal of Rheumatology
https://read.qxmd.com/read/37130597/theory-and-application-of-neuropsychological-underpinnings-of-adjudicative-competency
#24
COMMENT
Lori L Hauser
In their article, Aveson and colleagues postulate a model for understanding the neurocognitive underpinnings of competence to stand trial, and they present evidence to support that model for two specific facets: social intelligence and auditory verbal (episodic) memory. This commentary attempts to extend those findings by outlining specific interventions and assessment methods in the inpatient restoration setting that focus on strengthening these capacities and connecting them to the psycho legal context. It echoes the work of Aveson et al...
June 2023: Journal of the American Academy of Psychiatry and the Law
https://read.qxmd.com/read/37070263/a-public-health-perspective-to-reform-the-competence-to-stand-trial-system
#25
JOURNAL ARTICLE
Lauren E Kois, Daniel C Murrie, W Neil Gowensmith, Ira K Packer
No abstract text is available yet for this article.
April 18, 2023: Psychiatric Services: a Journal of the American Psychiatric Association
https://read.qxmd.com/read/37056195/evaluations-of-competence-to-stand-trial-are-evolving-amid-a-national-competency-crisis
#26
JOURNAL ARTICLE
Daniel C Murrie, W Neil Gowensmith, Lauren E Kois, Ira K Packer
Across the United States, court orders for competence to stand trial (CST) evaluations and competence restoration services have been increasing much more rapidly than states can provide these services, prompting what has been called a national "competency crisis." The challenge in providing timely competence restoration services has, in several jurisdictions, prompted a change in competence evaluations. Evaluators are more often required to address broader clinical issues-such as recommending placement or addressing the urgency of hospitalization-rather than addressing only CST...
April 13, 2023: Behavioral Sciences & the Law
https://read.qxmd.com/read/37036553/the-impact-of-chronotropic-incompetence-on-atrioventricular-conduction-times-in-heart-failure-patients
#27
JOURNAL ARTICLE
Hongxia Niu, Yinghong Yu, Vasanth Ravikumar, Michael R Gold
BACKGROUND: Intrinsic atrioventricular (AV) conduction is used to optimize AV intervals with cardiac resynchronization therapy (CRT) in most device algorithms. Atrial pacing and heart rate affect conduction times, but little is known regarding differeces among chronotropic incompetent(CI) and competent(CC) patients to guide programming. METHODS: RAVE was a multicenter prospective trial of CRT patients. Heart rate was increased with incremental atrial pacing and with submaximal exercise...
April 10, 2023: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://read.qxmd.com/read/37023371/perioperative-therapy-for-resectable-non-small-cell-lung-cancer-weighing-options-for-the-present-and-future
#28
REVIEW
Dipesh Uprety, Howard Jack West
Anatomic surgical resection followed by cisplatin-based platinum-doublet adjuvant chemotherapy has been a long-standing standard of care for patients with early-stage, resectable non-small-cell lung cancer (NSCLC). More recently, incorporating of immunotherapy and targeted therapy in the perioperative setting has demonstrated improved disease-free or event-free survival in biomarker-defined subsets of patients. This article summarizes the results of major trials that led to approvals beyond chemotherapy in the perioperative setting...
April 6, 2023: JCO oncology practice
https://read.qxmd.com/read/37020567/food-and-drug-administration-guidance-on-design-of-clinical-trials-for-gene-therapy-products-with-potential-for-genome-integration-or-genome-editing-and-associated-long-term-follow-up-of-research-subjects
#29
REVIEW
Daniel Eisenman, Scott Swindle
INTRODUCTION: With the burgeoning growth of the gene therapy industry, the Food and Drug Administration (FDA) has produced various guidance documents intended to help gene therapy manufacturers design their preclinical testing and clinical trials to facilitate the process of obtaining marketing approval. DISCUSSION: Biosafety professionals and institutional biosafety committees (IBCs) with oversight of clinical trials or biopharmaceutical manufacturing stand to benefit from understanding how these guidance documents set the standard for writing the clinical research protocols that are reviewed by IBCs...
December 1, 2022: Applied Biosafety: Journal of the American Biological Safety Association
https://read.qxmd.com/read/36934388/forensic-assessment-instruments-their-reliability-and-applicability-to-criminal-forensic-issues
#30
JOURNAL ARTICLE
Richard Rogers, Kamar Y Tazi, Eric Y Drogin
Forensic evaluations have advanced considerably with the development of specialized measures validated on forensic and correctional samples. Prior to this progress, such evaluations relied heavily on extrapolations from general psychological tests to crucial, legally relevant questions. Since then, decades of empirical work have produced forensic assessment instruments (FAIs) addressing psycholegal standards in addition to forensically relevant instruments (FRIs) examining issues central to forensic practice (e...
March 19, 2023: Behavioral Sciences & the Law
https://read.qxmd.com/read/36931860/an-uncomfortable-tension-reconciling-the-principles-of-forensic-psychology-and-cultural-competency
#31
REVIEW
Jude Bergkamp, Katharine A McIntyre, Magen Hauser
OBJECTIVE: State of Washington v. Sisouvanh (2012) was the first case in which an appellate court asserted the need for cultural competence in competency-to-stand-trial evaluations. A court reiterated this need in State of Washington v. Ortiz-Abrego (2017). Research in forensic psychology seldom addressed cultural considerations in pretrial evaluations until this past decade, but the growing body of literature pales in comparison to the work found in clinical and counseling psychology...
February 2023: Law and Human Behavior
https://read.qxmd.com/read/36928134/towards-a-heuristic-neuropsychological-model-of-adjudicative-competency
#32
JOURNAL ARTICLE
Olivia Aveson, Paul G Nestor, Kristy Klein
This study sought to delineate the neuropsychological processes that undergird the psycho-legal concept of competency to stand trial (CST). Accordingly, we retrospectively examined the relationship between clinical judgments of competence or incompetence of defendants committed to a maximum-security psychiatric facility and neuropsychological measures of cognitive and social intelligence and declarative memory. Results indicated that both groups (competent and incompetent) showed similar levels of depressed cognitive intelligence with Wechsler full-scale IQ levels falling in the upper end of the borderline range...
June 2023: Journal of the American Academy of Psychiatry and the Law
https://read.qxmd.com/read/36849185/working-with-persons-involved-in-the-legal-system-who-are-deaf
#33
JOURNAL ARTICLE
Lisa A Kuntz, Julie Pratt, Mark Cotterell
Between 2006 and 2016, the team at Whiting Forensic Hospital saw seven defendants who were deaf or hard of hearing for restoration to competence to stand trial. As a result of this experience, the team developed expertise in understanding Deaf Culture, the effects of hearing loss on psychological development and evaluation and treatment techniques for this population. Based on the team's experiences, we discuss best practices to ensure that deaf defendants have the same access as hearing persons to fair treatment by the legal system and to the education and treatment required for restoration...
February 27, 2023: Journal of the American Academy of Psychiatry and the Law
https://read.qxmd.com/read/36804937/evidence-based-teaching-in-contact-lenses-education-teaching-and-learning-strategies
#34
JOURNAL ARTICLE
Fabrizio Zeri, Frank Eperjesi, Craig Woods, Stefan Bandlitz, Ajay Kumar Bhootra, Mahesh R Joshi, Manbir Nagra, Helmer Schweizer, Shehzad A Naroo
INTRODUCTION: Contact lens (CL) practice is an ever-changing field with clinical knowledge, techniques and equipment continuously evolving. These new developments are backed with clinical trials and research to ensure that practitioners feel confident that there is an evidence base to support these advances. Evidence-based practice is now a crucial part of CL practice, and its importance also filters down to CL education. For example, lectures are one of the most popular tools for an educator but, is standing at the front of a lecture theatre full of students a more effective way of teaching than providing the same material for students to read by themselves? What evidence exists specific to CL education? METHOD: An expert panel of educators completed a comprehensive literature review of current evidence of teaching methods in CL training, or if not available then what can be learnt from other health care professional training that could be potentially applicable to CL education...
February 15, 2023: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://read.qxmd.com/read/36741811/jail-based-competency-restoration-services-in-the-united-states-the-need-the-controversy-the-impact-of-covid-19-and-implications-for-future-treatment-delivery
#35
JOURNAL ARTICLE
Douglas E Lewis, Peter Ash, Victoria C Roberts, Tomina J Schwenke, Melvin Pagán-González, Glenn J Egan
Jail-based competency restoration largely emerged as a method to address the backlog at forensic hospitals around the United States, as the number of justice-involved persons in need of restoration outgrew available beds. Jail-based competency restoration units (JBCRUs) appear to be highly effective and cost-saving. However, after the COVID-19 outbreak, services at some JBCRUs were stalled, as providers were forced to either quickly initiate or ramp up technology use to maintain services. The present study describes the course of programming for a JBCRU in Fulton County, Georgia, prior to and after the onset of COVID-19, during which time all treatment shifted to telehealth...
February 2023: Criminal Justice and Behavior
https://read.qxmd.com/read/36441985/high-dose-therapy-in-treatment-refractory-psychosis-a-retrospective-study
#36
JOURNAL ARTICLE
Mujeeb U Shad
Objective: To examine the impact of antipsychotic dose adjustments (mainly reduction) on the efficacy and tolerability of antipsychotic medications (APMs) to facilitate hospital discharge in long-term hospitalized forensic patients with treatment-refractory psychosis. Methods: This was a retrospective review of the medical charts of 22 patients with psychosis who were discharged from January 2020 to August 2020 from a long-term state psychiatric facility after restoration of their competency to stand trial...
November 24, 2022: Primary Care Companion to CNS Disorders
https://read.qxmd.com/read/36418051/underfunding-of-psychiatric-services-for-the-civilly-and-criminally-committed
#37
COMMENT
Gregory B Leong
As illustrated by the State of Oregon, a lack of inpatient psychiatric resources for civil commitment and restoration of competency to stand trial has become an increasing problem. In California, the government of Los Angeles County has studied this problem and identified potential solutions. The proposed solutions not surprisingly involve increased resources, including additional inpatient psychiatric beds. Despite recognition of a potential solution, however, sufficient resources have not yet appeared in Los Angeles County...
December 2022: Journal of the American Academy of Psychiatry and the Law
https://read.qxmd.com/read/36223939/the-dramatic-decline-of-civil-commitment-in-oregon-1972-to-2020
#38
JOURNAL ARTICLE
Thomas E Hansen, Joseph D Bloom, Amela Blekic
The rate of civil commitment in Oregon fell from 53.2/100,000 in 1972 to 9.2/100,000 in 2020. The paper discusses this decline in civil commitment as related to statutory and case law changes and complex interactions including bed availability at Oregon State Hospital (OSH). The latter was in turn influenced by the significant increase in the last decade of hospitalization at OSH of competence to stand trial evaluation and restoration (CST) patients. Multnomah County, which contains the city of Portland, was responsible for the largest number of investigations and commitments and led the state in using a 14-day diversion alternative to commitment...
October 12, 2022: Journal of the American Academy of Psychiatry and the Law
https://read.qxmd.com/read/36162861/the-state-of-forensic-literature-on-persons-with-intellectual-disability-who-sexually-offend
#39
JOURNAL ARTICLE
Kathryn Ann Baselice, Sara West
Persons with intellectual disability charged with sexual crimes (PWID/SC) pose a unique challenge for the forensic psychiatrist. They represent a heterogeneous group whose motivations and pathology range from a simple lack of adaptive functioning to more complex comorbid paraphilic disorders. Although there is a growing body of literature on the risk assessment and treatment of PWID/SC, there is a relative lack of guidance and research on the evaluation of these individuals throughout the legal processes that follow being charged with a sexual crime...
September 26, 2022: Journal of the American Academy of Psychiatry and the Law
https://read.qxmd.com/read/36017438/dissociative-identity-disorder-and-the-law-guilty-or-not-guilty
#40
REVIEW
Stefane M Kabene, Nazli Balkir Neftci, Efthymios Papatzikis
Dissociative identity disorder (DID) is a dissociative disorder that gained a significant rise in the past few decades. There has been less than 50 DID cases recorded between 1922 and 1972, while 20,000 cases are recorded by 1990. Therefore, it becomes of great significant to assess the various concepts related to DID to further understand the disorder. The current review has a goal of understanding whether an individual suffering from DID is legally responsible for the committed crime, and whether or not he or she can be considered competent to stand trial...
2022: Frontiers in Psychology
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