Karolina Tądel, Benita Wiatrak, Dorota Bodetko, Ewa Barg
INTRODUCTION: Metformin is a widely used drug in treating type 2 diabetes and insulin resistance and nowadays scientists are searching for new poten-tial and multiple roles in prevention and treatment of carcinogenic processes. AIM OF THE STUDY: The aim of the study was to compare the impact of normoglycemia and hyperglycemia with doses of metformin on vivacity and prolifer-ation of cancer cell lines (MCF-7, MCF-7/DX, A549, CCRF/CEM, THP-1, NHDF). MATERIAL AND METHODS: We designed our experiment using raising glucose environment (40 mM, 100 mM, 150 mM, 300 mM) and we added increasing con-centrations of metformin (5 mM, 10 mM, 20 mM, 30 mM)...
November 16, 2020: Pediatric Endocrinology, Diabetes, and Metabolism