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Early intervention psychosis

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https://www.readbyqxmd.com/read/29431144/paradigm-shift-purity-progress-and-the-origins-of-first-episode-psychosis
#1
Suze G Berkhout
First-episode psychosis has garnered significant attention and resources within mental health services in North America, Europe and Australia/New Zealand since the 1990s. Despite this widespread embrace, little scholarship exists that examines underlying concepts, ideologies and imagery embedded within the early intervention paradigm. In this paper, I offer a sociohistorical analysis of the emergence of first-episode psychosis and early intervention as entities in psychiatry, drawing on contemporary philosophical thought to explore various concepts embedded in them...
February 3, 2018: Medical Humanities
https://www.readbyqxmd.com/read/29417730/role-of-poor-sleep-in-determining-distress-in-caregivers-of-individuals-with-early-psychosis
#2
Lindsay M Smith, Juliana Onwumere, Thomas Craig, Elizabeth Kuipers
AIM: Looking after someone in the early stages of psychosis can have a negative impact on caregivers, but there is little clarity about which interventions, if any, caregivers should be offered. This study investigated sleep disturbances in early psychosis caregivers and the relationship between their sleep quality and distress. METHOD: In all, 79 caregivers of patients with a recent first episode of psychosis completed self-report measures including the Pittsburgh Sleep Quality Index (PSQI), the RAND 36-item Health Survey 1...
February 8, 2018: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29399952/the-last-taboo-the-experience-of-violence-in-first-episode-psychosis-caregiving-relationships
#3
Juliana Onwumere, Grace Parkyn, Stephanie Learmonth, Elizabeth Kuipers
OBJECTIVES: Informal caregiving relationships play an important role in facilitating recovery outcomes in psychosis. The relationship can serve as a source of positive experiences that co-exist alongside common challenges typically associated with mental health problems. People with psychosis, when compared to the general population, are more likely to perpetrate acts of violence, a relationship that is particularly evident during the first psychosis episode. Although victims of service user violence are typically people already known to them, such as informal carers, there remains a lack of understanding about their caring experiences and needs...
February 5, 2018: Psychology and Psychotherapy
https://www.readbyqxmd.com/read/29395604/patterns-and-predictors-of-trajectories-for-social-and-occupational-functioning-in-patients-presenting-with-first-episode-non-affective-psychosis-a-three-year-follow-up-study
#4
Wing Chung Chang, Angel On Ki Chu, Vivian Wing Yan Kwong, Corine Sau Man Wong, Christy Lai Ming Hui, Sherry Kit Wa Chan, Edwin Ho Ming Lee, Eric Yu Hai Chen
BACKGROUND: Functional impairment is prevalent in patients with first-episode psychosis (FEP). Longitudinal course of functioning in the early stage of psychotic illness is under-studied. In this report, we aimed to investigate the patterns and baseline predictors of social-occupational functional trajectories over 3 years, utilizing growth mixture modeling (GMM) analysis, in a large representative Chinese young FEP cohort in Hong Kong. METHOD: Six hundred seventeen consecutive patients aged 15-25 years presenting with first-episode non-affective psychosis to a specialized early intervention service were studied...
January 27, 2018: Schizophrenia Research
https://www.readbyqxmd.com/read/29387876/mortality-rates-after-the-first-diagnosis-of-psychotic-disorder-in-adolescents-and-young-adults
#5
Gregory E Simon, Christine Stewart, Bobbi Jo Yarborough, Frances Lynch, Karen J Coleman, Arne Beck, Belinda H Operskalski, Robert B Penfold, Enid M Hunkeler
Importance: Individuals with psychotic disorders have increased mortality, and recent research suggests a marked increase shortly after diagnosis. Objective: To use population-based data to examine overall and cause-specific mortality after first diagnosis of a psychotic disorder. Design, Setting, and Participants: This cohort study used records from 5 integrated health systems that serve more than 8 million members in 5 states. Members aged 16 through 30 years who received a first lifetime diagnosis of a psychotic disorder from September 30, 2009, through September 30, 2015, and 2 comparison groups matched for age, sex, health system, and year of diagnosis were selected from all members making an outpatient visit (general outpatient group) and from all receiving a first diagnosis of unipolar depression (unipolar depression group)...
January 31, 2018: JAMA Psychiatry
https://www.readbyqxmd.com/read/29385619/the-healing-healer-a-psychologist-s-personal-narrative-of-psychosis-and-early-intervention
#6
(no author information available yet)
No abstract text is available yet for this article.
January 29, 2018: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29382210/event-related-potentials-in-the-clinical-high-risk-chr-state-for-psychosis-a-systematic-review
#7
Jennifer R Lepock, Romina Mizrahi, Michele Korostil, R Michael Bagby, Elizabeth W Pang, Michael Kiang
There is emerging evidence that identification and treatment of individuals in the prodromal or clinical high-risk (CHR) state for psychosis can reduce the probability that they will develop a psychotic disorder. Event-related brain potentials (ERPs) are a noninvasive neurophysiological technique that holds promise for improving our understanding of neurocognitive processes underlying the CHR state. We aimed to systematically review the current literature on cognitive ERP studies of the CHR population, in order to summarize and synthesize the results, and their implications for our understanding of the CHR state...
January 1, 2018: Clinical EEG and Neuroscience: Official Journal of the EEG and Clinical Neuroscience Society (ENCS)
https://www.readbyqxmd.com/read/29373755/can-we-reduce-the-duration-of-untreated-psychosis-a-systematic-review-and-meta-analysis-of-controlled-interventional-studies
#8
Dominic Oliver, Cathy Davies, Georgia Crossland, Steffiany Lim, George Gifford, Philip McGuire, Paolo Fusar-Poli
Reduction of duration of untreated psychosis (DUP) is the key strategy of early interventions for improving the outcomes of first-episode psychosis. Although several controlled interventional studies have been conducted with the aim of reducing DUP, the results are highly inconsistent and conflicting. The current study systematically searches Web of Science and Ovid for English original articles investigating interventions adopted to reduce DUP, compared to a control intervention, up to April 6, 2017. Sixteen controlled interventional studies were retrieved, including 1964 patients in the intervention arm and 1358 in the control arm...
January 24, 2018: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29356438/impact-of-tobacco-alcohol-and-cannabis-use-on-treatment-outcomes-among-patients-experiencing-first-episode-psychosis-data-from-the-national-raise-etp-study
#9
Oladunni Oluwoye, Maria Monroe-DeVita, Ekaterina Burduli, Lydia Chwastiak, Sterling McPherson, Jon M McClellan, Michael G McDonell
AIM: The primary aim of this study was to examine the effect of recent tobacco, alcohol and cannabis use on treatment outcomes among participants experiencing first episode psychosis (FEP). METHODS: Secondary data analyses were conducted on 404 participants enrolled in the Recovery After an Initial Schizophrenia Episode-Early Treatment Program (RAISE-ETP) study. RAISE-ETP investigated the effectiveness of a coordinated specialty care (CSC) intervention for FEP in community mental health agencies in the United States...
January 22, 2018: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29353178/impulsivity-in-early-psychosis-a-complex-link-with-violent-behaviour-and-a-target-for-intervention
#10
V Moulin, P Golay, J Palix, P S Baumann, M-M Gholamrezaee, A Azzola, J Gasser, K Q Do, L Alameda, P Conus
BACKGROUND: Violent behaviour (VB) occurs in first episode of schizophrenia and can have devastating impact both on victims and patients themselves. A better knowledge of the underlying mechanisms of VB may pave the way to preventive treatments. OBJECTIVES: 1) To explore the nature of the link between impulsivity and VB in early psychosis (EP) patients; 2) To explore the interactions between impulsivity and substance abuse, insight, and positive symptoms, the main dynamic risk factors of VB described to date...
January 17, 2018: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/29332009/poststroke-psychosis-a-systematic-review
#11
REVIEW
Helle Stangeland, Vasiliki Orgeta, Vaughan Bell
A preregistered systematic review of poststroke psychosis examining clinical characteristics, prevalence, diagnostic procedures, lesion location, treatments, risk factors and outcome. Neuropsychiatric outcomes following stroke are common and severely impact quality of life. No previous reviews have focused on poststroke psychosis despite clear clinical need. CINAHL, MEDLINE and PsychINFO were searched for studies on poststroke psychosis published between 1975 and 2016. Reviewers independently selected studies for inclusion, extracted data and rated study quality...
January 13, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29328779/transforming-the-treatment-of-schizophrenia-in-the-united-states-the-raise-initiative
#12
Lisa B Dixon, Howard Goldman, Vinod H Srihari, John M Kane
The schizophrenia spectrum disorders are neurodevelopmental illnesses with a lifetime prevalence near 1%, producing extensive functional impairment and low expectations for recovery. Until recently, treatment in the United States has largely attempted to stabilize individuals with chronic schizophrenia. The identification and promotion of evidence-based practices for schizophrenia via the Patient Outcomes Research Team, combined with international studies supporting the value of early intervention, provided the foundation for the Recovery After an Initial Schizophrenia Episode (RAISE) project...
January 12, 2018: Annual Review of Clinical Psychology
https://www.readbyqxmd.com/read/29311665/hippocampal-dysfunction-in-the-pathophysiology-of-schizophrenia-a-selective-review-and-hypothesis-for-early-detection-and-intervention
#13
J A Lieberman, R R Girgis, G Brucato, H Moore, F Provenzano, L Kegeles, D Javitt, J Kantrowitz, M M Wall, C M Corcoran, S A Schobel, S A Small
Scientists have long sought to characterize the pathophysiologic basis of schizophrenia and develop biomarkers that could identify the illness. Extensive postmortem and in vivo neuroimaging research has described the early involvement of the hippocampus in the pathophysiology of schizophrenia. In this context, we have developed a hypothesis that describes the evolution of schizophrenia-from the premorbid through the prodromal stages to syndromal psychosis-and posits dysregulation of glutamate neurotransmission beginning in the CA1 region of the hippocampus as inducing attenuated psychotic symptoms and initiating the transition to syndromal psychosis...
January 9, 2018: Molecular Psychiatry
https://www.readbyqxmd.com/read/29303949/psychosis-risk-syndrome-what-now
#14
Othman Sentissi, Maria A Andreou, Clotilde Moeglin, Logos Curtis, Micaela Santos Brosch
BACKGROUND: Schizophrenia is a chronic psychiatric disorder that generally begins in late adolescence or early adulthood. This early onset is often linked with a devastating lifelong impact on both the social network and work capacities of the affected subjects. Beginning in the mid-1990s, several sets of diagnostic criteria aiming to identify "high-risk" patients were developed and applied in clinical studies. Short-term rates of onset of psychosis in this subgroup of subjects ranged from 20% to 40%...
November 2017: Journal of Psychiatric Practice
https://www.readbyqxmd.com/read/29287626/a-comparison-of-conversion-rates-clinical-profiles-and-predictors-of-outcomes-in-two-independent-samples-of-individuals-at-clinical-high-risk-for-psychosis-in-china
#15
Huijun Li, TianHong Zhang, LiHua Xu, YingYing Tang, HuiRu Cui, YanYan Wei, XiaoChen Tang, Kristen A Woodberry, Daniel I Shapiro, ChunBo Li, Larry J Seidman, JiJun Wang
OBJECTIVE: In a previous epidemiological study, we reported on the ascertainment and outcomes of "clinical high risk" (CHR) individuals at the Shanghai Mental Health Center (SMHC, "2011 cohort"). The current study compares demographic and clinical characteristics, including conversion rates, of this sample with a subsequently recruited, independent CHR sample and with published data from western samples. METHOD: A new sample of 100 CHR subjects ("2013 cohort") was selected based on screening and semi-structured interviews...
December 26, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/29282135/implementation-of-a-relatives-toolkit-impart-study-an-iterative-case-study-to-identify-key-factors-impacting-on-the-implementation-of-a-web-based-supported-self-management-intervention-for-relatives-of-people-with-psychosis-or-bipolar-experiences-in-a-national
#16
Fiona Lobban, Victoria Appleton, Duncan Appelbe, Johanna Barraclough, Julie Bowland, Naomi R Fisher, Sheena Foster, Sonia Johnson, Elizabeth Lewis, Céu Mateus, Barbara Mezes, Elizabeth Murray, Puffin O'Hanlon, Vanessa Pinfold, Jo Rycroft-Malone, Ron Siddle, Jo Smith, Chris J Sutton, Andrew Walker, Steven H Jones
BACKGROUND: Web-based interventions to support people to manage long-term health conditions are available and effective but rarely used in clinical services. The aim of this study is to identify critical factors impacting on the implementation of an online supported self-management intervention for relatives of people with recent onset psychosis or bipolar disorder into routine clinical care and to use this information to inform an implementation plan to facilitate widespread use and inform wider implementation of digital health interventions...
December 28, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/29275855/premorbid-iq-subgroups-in-first-episode-non-affective-psychosis-patients-long-term-sex-differences-in-function-and-neurocognition
#17
Rosa Ayesa-Arriola, Esther Setién-Suero, Karl David Neergaard, Àuria Albacete Belzunces, Fernando Contreras, Neeltje E M van Haren, Benedicto Crespo-Facorro
BACKGROUND: Low IQ has been associated with schizophrenia, even to the point of being posited as a possible causal factor for psychosis. However, individuals with normal and high IQ also develop psychotic illnesses. The aim of this study was to characterize premorbid IQ subgroups at first episode of psychosis (FEP). METHODS: The study sample comes from a large epidemiological, 3-year longitudinal, intervention program on psychosis containing individuals living in a catchment area in Spain...
December 21, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/29274223/a-survey-of-health-equity-practices-in-early-psychosis-intervention-programs-a-starting-point-for-improvement
#18
Avra Selick, Alexandra Lamoureux, Karen O'Connor, Janet Durbin
Equity has been identified as a core component of quality healthcare in Ontario. However, translating policy into practice can be challenging. This paper reports results from a province-wide survey of early psychosis intervention programs to assess the extent to which equity has been incorporated into program delivery. All 56 programs (100%) completed the survey. Results found that while most programs perceive that they are meeting equity aims, they reported limited use of practices to support this aim, and few systematically collect information on performance...
November 2017: Healthcare Policy, Politiques de Santé
https://www.readbyqxmd.com/read/29273021/randomised-controlled-trial-to-improve-health-and-reduce-substance-use-in-established-psychosis-impact-cost-effectiveness-of-integrated-psychosocial-health-promotion
#19
Margaret Heslin, Anita Patel, Daniel Stahl, Poonam Gardner-Sood, Manyara Mushore, Shubulade Smith, Kathryn Greenwood, Oluwadamilola Onagbesan, Conan O'Brien, Catherine Fung, Ruth Ohlsen, David Hopkins, Philippa Lowe, Maurice Arbuthnot, Stan Mutatsa, Gill Todd, Anna Kolliakou, John Lally, Brendon Stubbs, Khalida Ismail, Anthony David, Robin Murray, Zerrin Atakan, Fiona Gaughran
BACKGROUND: There is mounting evidence that people with severe mental illness have unhealthy lifestyles, high rates of cardiovascular and metabolic diseases, and greater risk of early mortality. This study aimed to assess the cost-effectiveness of a health promotion intervention seeking to improve physical health and reduce substance use in people with psychosis. METHODS: Participants with a psychotic disorder, aged 18-65 years old and registered on an enhanced care approach programme or equivalent were recruited from community mental health teams in six mental health trusts in England...
December 22, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/29261427/addiction-vulnerability-exploring-relationships-between-cigarette-smoking-substance-misuse-and-early-psychosis
#20
Vanessa Clark, Agatha M Conrad, Terry J Lewin, Amanda L Baker, Sean A Halpin, Ketrina A Sly, Juanita Todd
OBJECTIVE: Smoking rates in adolescents at risk of psychosis are significantly greater than those who are not at risk. Recent research suggests that cigarette smoking in adolescence may be a potential marker of transition to psychosis, although the exact relationship between the two remains unclear. Our aim was to examine whether tobacco smoking is a potential marker of transition to psychosis or subsequent episodes of psychosis, independently of other substance use, or alternatively, if smoking is essentially a general marker of later mental illness episodes...
December 20, 2017: Journal of Dual Diagnosis
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