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https://www.readbyqxmd.com/read/28088555/injury-in-pelvic-fracture-urethral-injury-is-membrano-bulbar-fact-or-myth
#1
Pankaj M Joshi, Devang J Desai, Darshan Shah, Devashree Joshi, Sanjay B Kulkarni
Pelvic fracture urethral injuries (PFUI) commonly result from motor vehicle collisions. The mechanism of injury conventionally thought was a shearing injury at the membranous urethra, which would destroy the striated sphincter. Continence would therefore depend on the bladder neck. Striated sphincter and site of injury has not been shown clearly on preoperative imaging. We demonstrate a our protocol of performing MRI whereby the membranous sphincter is seen intact and the injury is shown to be at the membrano-bulbar junction contrary to conventional belief...
January 11, 2017: Urology
https://www.readbyqxmd.com/read/28079513/high-dose-aspirin-for-kawasaki-disease-outdated-myth-or-effective-aid
#2
Gil Amarilyo, Yael Koren, Dafna Brik Simon, Maskit Bar-Meir, Hilla Bahat, Mona Hanna Helou, Amir Mendelson, Nofar Hezkelo, Gabriel Chodick, Yackov Berkun, Eli Eisenstein, Yonatan Butbul Aviel, Galia Barkai, Yoav Bolkier, Shai Padeh, Riva Brik, Phillip J Hashkes, Liora Harel, Yosef Uziel
OBJECTIVES: To compare the efficacy and safety of intravenous immunoglobulin (IVIG) plus high-dose aspirin (HDA) vs. IVIG plus low-dose aspirin (LDA) for the treatment of Kawasaki disease, with an emphasis on coronary artery outcomes. METHODS: This study was a retrospective, medical record review of paediatric patients with Kawasaki disease comparing 6 centres that routinely used HDA for initial treatment and 2 that used LDA in 2004-2013. Treatment response and adverse events were compared...
January 5, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28070666/health-beneficial-nutraceuticals-myth-or-reality
#3
REVIEW
Sascha Sauer, Annabell Plauth
The modern term nutraceutical sounds extremely promising to the health-conscious consumers and to the broad audience. But what are the scientific foundations of this hybrid between nutrient and pharmaceutical? Still, most compelling evidence for potential health-beneficial effects of nutraceuticals seem to derive from descriptive and correlative epidemiological data. Here, we will take an inventory of the general concepts of research to assess the current plethora of health claims that were made for nutraceutical products...
January 9, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28066026/response-to-letter-to-editor-internet-addiction-disorder-hype-a-myth
#4
P K Dalal, Debasish Basu
No abstract text is available yet for this article.
July 2016: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/28066025/internet-addiction-disorder-hype-a-myth
#5
Rajshekhar Bipeta
No abstract text is available yet for this article.
July 2016: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/28065597/a-global-analysis-of-the-receptor-tyrosine-kinase-protein-phosphatase-interactome
#6
Zhong Yao, Katelyn Darowski, Nicole St-Denis, Victoria Wong, Fabian Offensperger, Annabel Villedieu, Shahreen Amin, Ramy Malty, Hiroyuki Aoki, Hongbo Guo, Yang Xu, Caterina Iorio, Max Kotlyar, Andrew Emili, Igor Jurisica, Benjamin G Neel, Mohan Babu, Anne-Claude Gingras, Igor Stagljar
Receptor tyrosine kinases (RTKs) and protein phosphatases comprise protein families that play crucial roles in cell signaling. We used two protein-protein interaction (PPI) approaches, the membrane yeast two-hybrid (MYTH) and the mammalian membrane two-hybrid (MaMTH), to map the PPIs between human RTKs and phosphatases. The resulting RTK-phosphatase interactome reveals a considerable number of previously unidentified interactions and suggests specific roles for different phosphatase families. Additionally, the differential PPIs of some protein tyrosine phosphatases (PTPs) and their mutants suggest diverse mechanisms of these PTPs in the regulation of RTK signaling...
December 21, 2016: Molecular Cell
https://www.readbyqxmd.com/read/28064514/statistics-myth-busters
#7
Simon W Lam, Seth R Bauer, Wei Yang, Todd A Miano
Proficiency in research design and statistical analysis is crucial to the success of a clinical pharmacist. However, new pharmacy graduates and residents may not have received adequate training and education in these areas. During the authors' tenure as clinical pharmacists, several statistical "myths" were consistently maintained by residents and new clinical practitioners. The purpose of this narrative review is to discuss and dispel several of these statistical fallacies. The myths discussed involve 3 common areas of consideration when evaluating any clinical study: assessing the risk of bias from confounding (propensity score analysis and multivariable modeling), interpretation of the main study findings ( P values and hypothesis testing), and secondary evaluations (subgroup analyses)...
January 1, 2017: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/28062338/family-caregiver-participation-in-palliative-care-research-challenging-the-myth
#8
Samar Aoun, Susan Slatyer, Kathleen Deas, Cheryl Nekolaichuk
BACKGROUND: Despite international guidelines emphasizing consumer directed care and autonomous decisions in research participation, there is a common myth that research can be an additional and unwanted burden on patients and their family members. AIM: to examine the experiences and impact of research involvement on family caregivers (FC) of terminally ill people, focusing within home-based palliative care. DESIGN: and participants: 316 of 322 participants (98...
January 3, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28054198/strategies-for-working-with-asian-americans-in-mental-health-community-members-policy-perspectives-and-recommendations
#9
Suzie S Weng, Jennifer Spaulding-Givens
This qualitative study used snowball sampling of individuals known to provide informal assistance to Asian American community members with their mental health problems in a locality in the South where there has been an exponential increase of the Asian American population. The major themes found include: (1) the existence of cultural, language, knowledge, and transportation barriers and the importance of policy in addressing them; (2) the impact of the model minority myth and the need for inclusive policymaking; and (3) the unique service and policy needs of immigrants...
January 4, 2017: Administration and Policy in Mental Health
https://www.readbyqxmd.com/read/28052894/camus-and-modern-psychiatry-the-myth-of-sisyphus-reflection
#10
Thom Proven
No abstract text is available yet for this article.
January 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28048056/mo-fg-207a-00-radiation-and-cancer-reality-extrapolations-myths-practice
#11
Madan Rehani, Donald Miller
: There has been increasing use of CT scans globally. This increased use is not in itself of concern, and largely reflects the remarkable clinical benefits of CT. Inappropriate use of CT is, however, of concern, particularly as the potential for carcinogenic effects is yet to be fully understood. The first major media attention to cancer risk from CT scan arose from a series of papers and an Editorial published in AJR in 2001. This was followed by another series of papers in 2007 and associated media attention to the estimation of the number of cancer deaths that may occur in US as a result of radiation exposure from CT...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28043698/-healthcare-professionals-perceptions-of-islamic-beliefs-and-traditions-as-barriers-to-organ-donation-and-transplantation-in-algeria
#12
Nouhad Laidouni, Érica Briones-Vozmediano, Pilar Garrido Clemente, Diana Gil González
OBJECTIVE: The aim of this study is to explore healthcare professionals' perception of the influence of Islamic beliefs and traditions concerning organ donation and transplants in Algeria. METHODS: Exploratory qualitative study using individual semi-structured interviews of 17 healthcare professionals (9 men, 8 women) of different specialties in a University hospital in Algiers (Algeria). Qualitative content analysis of transcripts was performed using the computer software ATLAS...
December 30, 2016: Gaceta Sanitaria
https://www.readbyqxmd.com/read/28040090/masquelet-technique-myth-or-reality-a-systematic-review-and-meta-analysis
#13
Ilaria Morelli, Lorenzo Drago, David A George, Enrico Gallazzi, Sara Scarponi, Carlo L Romanò
INTRODUCTION: The induced membrane technique (IMT) or Masquelet technique, is a two-step surgical procedure used to treat pseudoarthroses and bony defects. Many authors have introduced variants to the technique. This study aims to compare the surgical variants of IMT and to evaluate its efficacy in achieving infection eradication and bone union. METHODS: A systematic review was carried out following the PRISMA guidelines. PubMed and other medical databases were explored using keywords "Masquelet technique" and "induced membrane technique"...
December 2016: Injury
https://www.readbyqxmd.com/read/28039887/the-mitochondrial-replacement-therapy-myth
#14
Tina Rulli
This article argues that two forms of mitochondrial replacement therapy, maternal spindle transfer (MST) and pro-nuclear transfer (PNT), are not therapies at all because they do not treat children who are coming into existence. Rather, these technologies merely create healthy children where none was inevitable. Even if creating healthy lives has some value, it is not to be confused with the medical value of a cure or therapy. The article addresses a recent Bioethics article, 'Mitochondrial Replacement: Ethics and Identity,' by Wrigley, Wilkinson, and Appleby, who argue that PNT is morally favorable to MST due to the Non-Identity Problem...
December 30, 2016: Bioethics
https://www.readbyqxmd.com/read/28032083/dihydropyrimidine-dehydrogenase-mutation-in-neoadjuvant-chemotherapy-in-head-and-neck-cancers-myth-or-reality
#15
Vijay M Patil, Vanita Noronha, Amit Joshi, Saurabh Zanwar, Anant Ramaswamy, Supreeta Arya, Abhishek Mahajan, Atanu Bhattacharjee, Kumar Prabhash
PURPOSE: The docetaxel, 5-fluorouracil (5-FU), and cisplatin (TPF) regimen in India is associated with high percentages of Grade 3-4 toxicity. This analysis was planned to evaluate the incidence of dihydropyrimidine dehydrogenase (DPD) mutation in patients with severe gastrointestinal toxicity, to assess whether the mutation could be predicted by a set of clinical criteria and whether it has any impact on postneoadjuvant chemotherapy response. METHODS: All consecutive patients who received TPF regimen in head and neck cancers between January 2015 and April 2015 were selected...
October 2016: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/28031302/a-review-of-10-years-of-vasectomy-programming-and-research-in-low-resource-settings
#16
REVIEW
Dominick Shattuck, Brian Perry, Catherine Packer, Dawn Chin Quee
Vasectomy is a highly effective and safe contraceptive method for couples who want to stop childbearing, but only 2.4% of men around the world use this method. We conducted an extensive review of the vasectomy research literature and programmatic reports, published between April 2005 and April 2015, to synthesize barriers and facilitators to vasectomy adoption. Of the more than 230 documents initially retrieved in our search, we ultimately included 75 documents in our review and synthesized the findings according to the Supply-Enabling Environment-Demand (SEED) Programming Model...
December 23, 2016: Global Health, Science and Practice
https://www.readbyqxmd.com/read/28030406/1-5-ce-test-hours-human-papillomavirus-related-oral-cancers-the-nurse-s-role-in-mitigating-stigma-and-dispelling-myths
#17
Emily Contrada
No abstract text is available yet for this article.
January 2017: American Journal of Nursing
https://www.readbyqxmd.com/read/28030405/ce-human-papillomavirus-related-oral-cancers-the-nurse-s-role-in-mitigating-stigma-and-dispelling-myths
#18
Anne Katz
: The prevalence of human papillomavirus (HPV)-related oral cancers has been rising, the cancers occurring in adults at a younger age than HPV-negative oral cancers typically do and in men more often than women. Patients who are diagnosed often don't understand the disease's etiology. Because HPV is sexually transmitted, diagnosis with an HPV-related oral cancer may prompt feelings of shame, embarrassment, and guilt. There are currently three vaccines for HPV. It's essential for nurses to educate patients on HPV transmission and HPV-related oral cancer, thus helping to mitigate the stigma and dispel myths, and to promote vaccination in at-risk populations, including children and young adults...
January 2017: American Journal of Nursing
https://www.readbyqxmd.com/read/28028418/buccal-corridors-a-fact-or-a-myth-in-the-eyes-of-laymen
#19
Omnia A Elhiny, Asmaa Y Harhash
AIM: This study aimed to investigate laymen knowledge of the existence of the buccal corridor and whether it was an important factor for them in judging smile attractiveness and the effect of introducing the knowledge to them on their further judgment. MATERIALS AND METHODS: Nine subjects were randomly selected with variable buccal corridor percentages. They were coached to smile in a posed fashion and full face smile photographs were taken from a standardised distance...
December 15, 2016: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28024137/-secrets-of-the-red-headed
#20
REVIEW
Zygmunt Zdrojewicz, Małgorzata Kowalik, Adam Jagodziński
Only 1-2% of people is red-headed but in the Russian Udmurt Republic or United Kingdom they can be met more often. A specific variant of MC1R gene (R allele) is responsible for the red hair. The gene encodes a receptor for melanocortins. These substances stimulate melanocytes to product melanin- a dye of the skin which is transported to keratinocytes. It protects a cellular nucleus from ultraviolet radiation. Melanin has two types: eumelanin which is dark brown or even black and red/orange pheomelanin. The second one is mostly observed in red-headed which is caused by R allele...
December 22, 2016: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
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