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https://www.readbyqxmd.com/read/28905640/neurobiological-mechanisms-of-exercise-and-psychotherapy-in-depression-the-speed-study-rationale-design-and-methodological-issues
#1
Stephan Heinzel, Michael A Rapp, Thomas Fydrich, Andreas Ströhle, Christina Terán, Gunnar Kallies, Melanie Schwefel, Andreas Heissel
BACKGROUND/AIMS: Even though cognitive behavioral therapy has become a relatively effective treatment for major depressive disorder and cognitive behavioral therapy-related changes of dysfunctional neural activations were shown in recent studies, remission rates still remain at an insufficient level. Therefore, the implementation of effective augmentation strategies is needed. In recent meta-analyses, exercise therapy (especially endurance exercise) was reported to be an effective intervention in major depressive disorder...
September 1, 2017: Clinical Trials: Journal of the Society for Clinical Trials
https://www.readbyqxmd.com/read/28902127/altered-gene-expression-of-rnf34-and-pacap-possibly-involved-in-mechanism-of-exercise-induced-analgesia-for-neuropathic-pain-in-rats
#2
Shintaro Yamaoka, Yusuke Oshima, Hideki Horiuchi, Tadao Morino, Masayuki Hino, Hiromasa Miura, Tadanori Ogata
Despite the availability of several modalities of treatment, including surgery, pharmacological agents, and nerve blocks, neuropathic pain is often unresponsive and sometimes progresses to intractable chronic pain. Although exercise therapy is a candidate for treatment of neuropathic pain, the mechanism underlying its efficacy has not been elucidated. To clarify the molecular mechanism for pain relief induced by exercise, we measured Rnf34 and Pacap mRNA levels in the spinal cord dorsal horn of SNL rats, a model of neuropathic pain...
September 13, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28895770/the-use-of-platelet-rich-plasma-prp-in-the-treatment-of-gastrocnemius-strains-a-retrospective-observational-study
#3
Paolo Borrione, Chiara Fossati, Maria Teresa Pereira, Silvana Giannini, Marco Davico, Carlo Minganti, Fabio Pigozzi
The aim of the present retrospective observational study was to evaluate the time of functional recovery following a specific combined therapeutic approach characterized by an active exercise therapy carried out immediately after Platelet-rich plasma (PRP) injections for the treatment of the muscular lesion of the distal musculotendinous junction of the gastrocnemius medial head.Medical records of 31 subjects treated with three PRP intra-lesional ultrasound guided injections and 30 patients treated with the standard therapeutic approach (control group) were analyzed...
September 12, 2017: Platelets
https://www.readbyqxmd.com/read/28893711/supervised-exercise-therapy-for-intermittent-claudication-is-increasingly-endorsed-by-dutch-vascular-surgeons
#4
David Hageman, Gert-Jan Lauret, Lindy N M Gommans, Mark J W Koelemay, Marc R H M van Sambeek, Marc R M Scheltinga, Joep A W Teijink
INTRODUCTION: Although supervised exercise therapy (SET) is generally accepted as an effective noninvasive treatment for intermittent claudication (IC), Dutch vascular surgeons were initially somewhat hesitant as reported by a 2011 questionnaire study. Later on, a nationwide multidisciplinary network for SET was introduced in the Netherlands. The aim of this questionnaire study was to determine possible trends in conceptions among Dutch vascular surgeons regarding the prescription of SET...
September 8, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28878480/anti-gravity-treadmill-can-promote-aerobic-exercise-for-lower-limb-osteoarthritis-patients
#5
Toshihiro Kawae, Yukio Mikami, Kouki Fukuhara, Hiroaki Kimura, Nobuo Adachi
[Purpose] The anti-gravity treadmill (Alter-G(®)) allows the load on the lower limbs to be adjusted, which is considered useful for patients with lower limb osteoarthritis. The aim of the present study was to examine the effects of aerobic exercise using an anti-gravity treadmill in patients with lower limb osteoarthritis by using a cardiopulmonary exercise load monitoring system. [Subjects and Methods] The subjects were 20 patients with lower limb osteoarthritis. These subjects walked naturally for 8 minutes and then walked on the Alter-G for 8 minutes at their fastest speed at a load where lower limb pain was alleviated...
August 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28878453/pulsed-electromagnetic-field-with-or-without-exercise-therapy-in-the-treatment-of-benign-prostatic-hyperplasia
#6
Hany M Elgohary, Sayed A Tantawy
[Purpose] To investigate the effect of pulsed electromagnetic field with or without exercise therapy in the treatment of benign prostatic hyperplasia. [Subjects and Methods] Sixty male patients aged 55-65 years with benign prostatic hyperplasia were invited to participate in this study. Patients were randomly assigned to Group A (n=20; patients who received pulsed electromagnetic field in addition to pelvic floor and aerobic exercises), Group B (n=20; patients who received pulsed electromagnetic field), and Group C (n=20; patients who received placebo electromagnetic field)...
August 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28874320/exercise-training-for-intermittent-claudication
#7
Mary M McDermott
OBJECTIVE: The objective of this study was to provide an overview of evidence regarding exercise therapies for patients with lower extremity peripheral artery disease (PAD). METHODS: This manuscript summarizes the content of a lecture delivered as part of the 2016 Crawford Critical Issues Symposium. RESULTS: Multiple randomized clinical trials demonstrate that supervised treadmill exercise significantly improves treadmill walking performance in people with PAD and intermittent claudication symptoms...
September 2, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28865049/exercise-therapy-for-treatment-of-supraspinatus-tears-does-not-alter-glenohumeral-kinematics-during-internal-external-rotation-with-the-arm-at-the-side
#8
Gerald A Ferrer, R Matthew Miller, Jason P Zlotnicki, Scott Tashman, James J Irrgang, Volker Musahl, Richard E Debski
PURPOSE: Rotator cuff tears are a significant clinical problem, with exercise therapy being a common treatment option for patients. Failure rates of exercise therapy may be due to the failure to improve glenohumeral kinematics. Tears involving the supraspinatus may result in altered glenohumeral kinematics and joint instability for internal/external rotation with the arm at the side because not all muscles used to stabilize the glenohumeral joint are functioning normally. The objective of the study is to assess in vivo glenohumeral kinematic changes for internal/external rotation motions with the arm at the side of patients with a symptomatic full-thickness supraspinatus tear before and after a 12-week exercise therapy programme...
September 1, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28862315/effectiveness-of-postoperative-home-exercise-compared-with-usual-care-on-kinesiophobia-and-physical-activity-in-spondylolisthesis-a-randomized-controlled-trial
#9
Outi Ilves, Arja Häkkinen, Joost Dekker, Marko Wahlman, Sami Tarnanen, Liisa Pekkanen, Jari Ylinen, Hannu Kautiainen, Marko Neva
OBJECTIVE: To study the effectiveness of a 12-month exercise therapy on kinesiophobia and physical activity in patients with spondylolisthesis after lumbar spine fusion. DESIGN: Randomized controlled trial. SUBJECTS: Patients (n = 98) with spondylolisthesis who had undergone lumbar spine fusion. METHODS: All patients (mean age 59 years) had received lumbar spine fusion surgery and identical postoperative instructions...
September 1, 2017: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28856518/changes-of-patient-reported-outcomes-and-protein-fingerprint-biomarkers-after-exercise-therapy-for-axial-spondyloarthritis
#10
Marketa Husakova, Anne Sofie Siebuhr, Karel Pavelka, Maja Spiritovic, Anne-Christine Bay-Jensen, Andrea Levitova
The objective of this study was to investigate the patient-reported outcomes (PROs) and matrix metalloproteinase (MMP) derived extracellular matrix (ECM) biomarkers in non-radiographic (nr)-axial spondyloarthritis (axSpA) and radiographic (r)-axSpA after exercise intervention. Forty-six axSpA patients with stable disease and treatment underwent 24 weeks long exercise intervention. The clinical and laboratory assessments were performed at baseline and at follow-up. The PROs included evaluation of patient's global disease activity (PGDA), disease activity (DA7), pain (PAIN7) and fatigue during last week and quality of life questionnaires...
August 30, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28836351/efficacy-and-safety-of-once-weekly-oral-trelagliptin-switched-from-once-daily-dipeptidyl-peptidase-4-inhibitor-in-patients-with-type-2-diabetes-mellitus-an-open-label-phase-3-exploratory-study
#11
Nobuya Inagaki, Hiroki Sano, Yoshifumi Seki, Shingo Kuroda, Kohei Kaku
INTRODUCTION: Trelagliptin, a novel once-weekly oral dipeptidyl peptidase-4 (DPP-4) inhibitor, has shown favorable efficacy and safety in type 2 diabetes mellitus (T2DM) patients. Trelagliptin was launched in Japan and is expected to be initially used for switchover from a daily DPP-4 inhibitor in the clinical setting. Thus, this study was planned to explore the efficacy and safety of trelagliptin after a daily DPP-4 inhibitor was switched to it. MATERIALS AND METHODS: This was an open-label phase 3 exploratory study to evaluate the efficacy and safety of trelagliptin in Japanese T2DM patients who had stable glycemic control on once-daily sitagliptin therapy...
August 24, 2017: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/28833185/expiratory-muscle-strength-training-for-radiation-associated-aspiration-after-head-and-neck-cancer-a-case-series
#12
Katherine A Hutcheson, Martha P Barrow, Emily K Plowman, Stephen Y Lai, Clifton David Fuller, Denise A Barringer, George Eapen, Yiqun Wang, Rachel Hubbard, Sarah K Jimenez, Leila G Little, Jan S Lewin
OBJECTIVE/HYPOTHESIS: Expiratory muscle strength training (EMST) is a simple, inexpensive, device-driven exercise therapy. Therapeutic potential of EMST was examined among head and neck cancer survivors with chronic radiation-associated aspiration. STUDY DESIGN: Retrospective case series. METHODS: Maximum expiratory pressures (MEPs) were examined among n = 64 radiation-associated aspirators (per penetration-aspiration scale score ≥ 6 on modified barium swallow)...
August 22, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28830024/cognitive-remediation-training-improves-performance-in-patients-with-chronic-fatigue-syndrome
#13
Richard L McBride, Sarah Horsfield, Carolina X Sandler, Joanne Cassar, Sally Casson, Erin Cvejic, Uté Vollmer-Conna, Andrew R Lloyd
Neurocognitive disturbance with subjectively-impaired concentration and memory is a common, disabling symptom reported by patients with chronic fatigue syndrome (CFS). We recently reported preliminary evidence for benefits of cognitive remediation as part of an integrated cognitive-behavioral therapy (CBT)/ graded exercise therapy (GET) program. Here, we describe a contemporaneous, case-control trial evaluating the effectiveness of an online cognitive remediation training program (cognitive exercise therapy; CET) in addition to CBT/GET (n=36), compared to CBT/GET alone (n=36)...
August 18, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28829873/exercise-therapy-offers-modest-benefits-for-chronic-fatigue
#14
Anita Slomski
No abstract text is available yet for this article.
August 22, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28827270/study-protocol-for-a-randomised-controlled-trial-of-meniscal-surgery-compared-with-exercise-and-patient-education-for-treatment-of-meniscal-tears-in-young-adults
#15
Søren Thorgaard Skou, Martin Lind, Per Hölmich, Hans Peter Jensen, Carsten Jensen, Muhammad Afzal, Uffe Jørgensen, Jonas Bloch Thorlund
INTRODUCTION: Arthroscopic surgery is a very common orthopaedic procedure. While several trials have investigated the effect of knee arthroscopy for middle-aged and older patients with meniscal tears, there is a paucity of trials comparing meniscal surgery with non-surgical treatment for younger adults. The aim of this randomised controlled trial (RCT) is to investigate if early arthroscopic surgery is superior to exercise therapy and education, with the option of later surgery if needed, in improving pain, function and quality of life in younger adults with meniscal tears...
August 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/28814244/history-prevalence-and-assessment-of-limited-joint-mobility-from-stiff-hand-syndrome-to-diabetic-foot-ulcer-prevention
#16
Piergiorgio Francia, Roberto Anichini, Giuseppe Seghieri, Alessandra De Bellis, Massimo Gulisano
INTRODUCTION: Diabetes mellitus (DM) is one of the most important global public health problems. Patients with DM may develop different dreaded complications during their lifetime, one of which is limited joint mobility (LJM). Joint abnormalities and LJM are problems that can arise at disease onset, and progressively worsen together with the disease. Because LJM shares causal factors with other chronic diabetes-induced complications, its study has been considered useful for monitoring the risk of developing other chronic complications due to DM such as vascular disease or diabetic foot...
August 16, 2017: Current Diabetes Reviews
https://www.readbyqxmd.com/read/28813889/design-of-a-clinically-relevant-upper-limb-exoskeleton-robot-for-stroke-patients-with-spasticity
#17
Dong Jin Lee, Sung Jin Bae, Sung Ho Jang, Pyung Hun Chang
The purpose of this research is to propose a design of a clinically relevant upper-limb (hand, wrist, and elbow) exoskeleton that meets the clinical requirements. At first, the proposed robot was designed to have sufficient torque for passive exercise therapy and spasticity measurement of post-stroke patients with spasticity (grade 3 or lower in Modified Ashworth Scale). Because the therapy of patients with high level spasticity could be laborious for therapists by increased muscle tone, and the patients tend not to get enough rehabilitation treatment...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28805777/-accelerated-postoperative-rehabilitation-in-patients-undergoing-pancreatoduodenectomy
#18
Z A Kovalenko, V K Lyadov, K V Lyadov
AIM: To assess safety and clinical-economic effectiveness of complex postoperative rehabilitation after pancreatoduodenectomy. MATERIAL AND METHODS: 73 patients were included in the study. Main group consisted of 39 patients who underwent accelerated postoperative rehabilitation that was developed in our clinic. In the control group of 34 patients this protocol was not applied. The main components of rehabilitation were multicomponent analgesia, early enteral nutrition, physical rehabilitation by using of exercise therapy and physiotherapy...
2017: Khirurgiia
https://www.readbyqxmd.com/read/28805528/pace-investigators-response-is-misleading-regarding-patient-survey-results
#19
Karen D Kirke
The PACE investigators' citation of a patient survey might mislead readers into thinking that the experience of people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) supports PACE findings. In fact, patient survey evidence directly contradicts the results of the PACE trial. A review of survey data published between 2001 and 2015 reveals that for most patients, graded exercise therapy leads to worsening of symptoms, cognitive behavioural therapy leads to no change in symptoms, and pacing leads to improvement...
August 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/28805527/bias-misleading-information-and-lack-of-respect-for-alternative-views-have-distorted-perceptions-of-myalgic-encephalomyelitis-chronic-fatigue-syndrome-and-its-treatment
#20
Ellen Goudsmit, Sandra Howes
The PACE trial is one of the most recent studies evaluating cognitive behavioural therapy and graded exercise therapy for myalgic encephalomyelitis/chronic fatigue syndrome. These interventions are based on a model which assumes that symptoms are perpetuated by factors such as misguided beliefs and a lack of activity. Our analysis indicates that the researchers have shown significant bias in their accounts of the literature and may also have overstated the effectiveness of the above treatments. We submit that their approach to criticisms undermines the scientific process and is inconsistent with best practice...
August 2017: Journal of Health Psychology
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