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John Y K Lee, John T Pierce, Sukhmeet K Sandhu, Dmitriy Petrov, Andrew I Yang
OBJECTIVE Endoscopic surgery has revolutionized surgery of the ventral skull base but has not yet been widely adopted for use in the cerebellopontine angle. Given the relatively normal anatomy of the cerebellopontine angle in patients with trigeminal neuralgia (TN), the authors hypothesized that a fully endoscopic microvascular decompression (E-MVD) might provide pain outcomes equivalent to those of microscopic MVD (M-MVD) but with fewer complications. METHODS The authors conducted a single-institution, single-surgeon retrospective study with patients treated in the period of 2006-2013...
July 29, 2016: Journal of Neurosurgery
Marcelo Martins Kalytczak, Paulo Roberto Garcia Lucareli, Amir Curcio Dos Reis, André Serra Bley, Daniela Aparecida Biasotto-Gonzalez, João Carlos Ferrari Correa, Fabiano Politti
Possible delays in pre-activation or deficiencies in the activity of the dynamic muscle stabilizers of the knee and hip joints are the most common causes of the patellofemoral pain syndrome (PFPS). The aim of the study was to compare kinematic variables and electromyographic activity of the vastus lateralis, biceps femoris, gluteus maximus and gluteus medius muscles between patients with PFPS and health subjects during the single leg triple hop test (SLTHT). This study included 14 female with PFPS (PFPS group) and 14 female healthy with no history of knee pain (Healthy group)...
September 2016: Gait & Posture
Sadi Turkan, Mehmet Kalkan, Ozan Ekmekcioglu, Hacer Haltas, Coskun Sahin
Paratesticular fibrous pseudotumors (PFPs) are rare pathologies with quite wide and variable topographic-morphological features. It is difficult to distinguish PFPs from malignant masses. Treatment can be done by resection of the mass. We reported a young patient's findings about this rare pathology.
June 28, 2016: Rare Tumors
Gul Deniz Yilmaz Yelvar, Yasemin Çirak, Murat Dalkilinç, Yasemin Parlak Demir, Gul Baltaci, Mahmut Kömürcü, Gul Deniz Yilmaz Yelvar
BACKGROUND: Postural control allows performance of daily and sports activities. The previous studies show that postural sway inceases in orthopaedic injuries such as osteoarthritis and total knee arthroplasty. OBJECTIVE: To compare postural sway, risk of falling and function between individuals with and without patellofemoral pain syndrome (PFS). METHODS: This study included 22 subjects with patellofemoral pain syndrome, age-matched pain-free 22 females serving as a control group...
June 30, 2016: Journal of Back and Musculoskeletal Rehabilitation
Justin M Lantz, Alicia J Emerson-Kavchak, John J Mischke, Carol A Courtney
BACKGROUND AND PURPOSE: Patellofemoral pain syndrome (PFPS) is a common source of anterior knee pain. Controversy exists over the exact clinical findings which define PFPS, thus, diagnosis and management can be challenging for clinicians. There is paucity in the literature concerning joint mobilization as treatment for PFPS, particularly at the tibiofemoral joint, as standard management is currently focused on therapeutic exercise, orthotics, bracing and taping. Therefore, the purpose of this case report is to describe the effects of tibiofemoral joint mobilization in the successful treatment of an individual with chronic PFPS as it relates to pain, function and central processing of pain...
June 2016: International Journal of Sports Physical Therapy
Qian-Li Xue, Jing Tian, Linda P Fried, Rita R Kalyani, Ravi Varadhan, Jeremy D Walston, Karen Bandeen-Roche
Different phenotypes have increasingly been used as tools for clinical characterization of frailty among older adults. Although there have been studies about the comparability and effectiveness of various simplifications and approximations of existing frailty phenotypes for risk prediction, there have been no studies in which investigators evaluated the stability of the clinical characterization achieved. In the present study, we used baseline (1992-1996) data from 786 community-dwelling women who were 70-79 years of age in the Women's Health and Aging Study I and II to compare physical frailty phenotypes (PFPs)...
June 1, 2016: American Journal of Epidemiology
Wolf Petersen, Andree Ellermann, Ingo Volker Rembitzki, Sven Scheffler, Mirco Herbort, Gert Peter Brüggemann, Raymond Best, Thore Zantop, Christian Liebau
BACKGROUND: It has been previously shown that exercise programs for patellofemoral pain syndrome (PFPS) can be supported by medially directed taping. Evidence supporting the use of patellar braces is limited because previous studies have been low quality. The aim of this study is to compare the outcomes of patients with PFPS after treatment with a medially directed patellar realignment brace and supervised exercise. METHODS: In a prospective randomized multicenter trial, 156 patients with PFPS were included and randomly assigned to 6 weeks of supervised physiotherapy in combination with the patellar realignment brace, or supervised physiotherapy alone...
July 2016: Archives of Orthopaedic and Trauma Surgery
Gabriel Peixoto Leão Almeida, Ana Paula de Moura Campos Carvalho E Silva, Fábio Jorge Renovato França, Maurício Oliveira Magalhães, Thomaz Nogueira Burke, Amélia Pasqual Marques
OBJECTIVE: To investigate the relationship between the q-angle and anterior knee pain severity, functional capacity, dynamic knee valgus and hip abductor torque in women with patellofemoral pain syndrome (PFPS). METHODS: This study included 22 women with PFPS. The q-angle was assessed using goniometry: the participants were positioned in dorsal decubitus with the knee and hip extended, and the hip and foot in neutral rotation. Anterior knee pain severity was assessed using a visual analog scale, and functional capacity was assessed using the anterior knee pain scale...
March 2016: Revista Brasileira de Ortopedia
Jason Bonar, Shannon Clutton Carr, Diana De Carvalho, Jay S Wunder
Balancing the assessment of musculoskeletal dysfunctions with a high level of suspicion for non-mechanical origins can be a challenge for the clinician examining a sports injury. Without timely diagnosis, non-mechanical complaints could result in surgery or loss of limb. This case describes the discovery of a Giant Cell Tumor of Bone (GCTB) following the re-evaluation of an athlete who had undergone five years of conservative management for patellofemoral pain syndrome (PFPS). Knee injuries account for 32.6% of sports injuries with PFPS being the most common and most likely diagnosis for anterior knee pain...
March 2016: Journal of the Canadian Chiropractic Association
Qianling Sun, Mengmeng Dong, Zhihui Wang, Changdong Wang, Deqiao Sheng, Zhihong Li, Debin Huang, Chengfu Yuan
Polysaccharides from medicinal plants exert antitumor activity in many cancers. Our previous study demonstrated that polysaccharides extracted from the selenium-enriched Pyracantha fortuneana (Se-PFPs) showed antiproliferative effect in breast cancer cell line. This study aimed to investigate the antitumor effect of Se-PFPs in ovarian cancer cells in vitro and in vivo. Se-PFPs could decrease cell viability, induce apoptosis, and inhibit migratory and invasive potentials in HEY and SKOV3 cells. These findings are supported by reduced expression of cyclin D1, Bcl-2 and MMP-9, enhanced cleavage of PARP and caspase-3, elevated activity of caspase-3 and caspase-9, and EMT (epithelial to mesenchymal transition) inhibition (elevated expression of E-cadherin and cytokeratin 19, and reduced expression of N-cadherin, vimentin, ZEB1 and ZEB2)...
May 10, 2016: Oncotarget
Costas Papadopoulos, Antonis Constantinou, Areti-Zoi Cheimonidou, Dimitrios Stasinopoulos
PURPOSE: To cross-culturally adapt and validate the Greek version of the Kujala anterior knee pain scale (KAKPS). METHODS: The Greek KAKPS was translated from the original English version following standard forward and backward translation procedures. The survey was then conducted in clinical settings by a questionnaire comprising the Greek KAKPS and patellofemoral pain syndrome (PFPS) severity scale. A total of 130 (62 women and 68 men) Greek-reading patients between 18 and 45 years old with anterior knee pain (AKP) for at least four weeks were recruited from physical therapy clinics...
April 6, 2016: Disability and Rehabilitation
Anna Cronström, Mark W Creaby, Jenny Nae, Eva Ageberg
BACKGROUND: Increased knee abduction angle during activity is suggested to be a risk factor for sustaining an anterior cruciate ligament (ACL) injury or developing patellofemoral pain syndrome (PFPS). Knowledge of the modifiable mechanisms that are associated with increased knee abduction will aid in the appropriate design of preventive and rehabilitative strategies for these injuries. OBJECTIVE: Our objective was to systematically review modifiable mechanisms contributing to increased knee abduction in healthy people and in individuals with an ACL injury or PFPS...
April 5, 2016: Sports Medicine
Xiuyuan Ou, Wangliang Zheng, Yiwei Shan, Zhixia Mu, Samuel R Dominguez, Kathryn V Holmes, Zhaohui Qian
UNLABELLED: The fusion peptides (FP) play an essential role in fusion of viral envelope with cellular membranes. The location and properties of the FPs in the spike (S) glycoproteins of different coronaviruses (CoV) have not yet been determined. Through amino acid sequence analysis of S proteins of representative CoVs, we identified a common region as a possible FP (pFP) that shares the characteristics of FPs of class I viral fusion proteins, including high Ala/Gly content, intermediate hydrophobicity, and few charged residues...
June 15, 2016: Journal of Virology
Dalia Stern, Jennifer M Poti, Shu Wen Ng, Whitney R Robinson, Penny Gordon-Larsen, Barry M Popkin
BACKGROUND: In the literature, it has been suggested that there are race-ethnic disparities in what Americans eat. In addition, some studies have shown that residents of African American and low-income neighborhoods have less access to grocery stores and supermarkets, which tend to stock healthier foods. However, it is unclear whether differences in food shopping patterns contribute to the poorer nutrient profile of food purchases made by racial-ethnic minorities. OBJECTIVES: We examined whether the mix of food stores where people shop (i...
April 2016: American Journal of Clinical Nutrition
Behnam Akhbari, Mahyar Salavati, Farshid Mohammadi, Ziaeddin Safavi-Farokhi
PURPOSE: To determine the intra- and inter-session reliability of balance performance in people with patellofemoral pain syndrome (PFPS) and matched controls. METHODS: In this methodological study, single-leg-stance performance of 15 participants with unilateral PFPS and 15 healthy matched controls was assessed using the Biodex Balance System (BBS) under 4 task difficulty levels (static and dynamic, with and without visual feedback). Intra-class correlation coefficients (ICCs), standard errors of measurement, and coefficients of variation were calculated for the overall stability index, anterior-posterior stability index, and medial-lateral stability index...
August 2015: Physiotherapy Canada. Physiothérapie Canada
Brian C Lau, Daniel U Thuillier, Valentina Pedoia, Ellison Y Chen, Zhihong Zhang, Brian T Feeley, Richard B Souza
BACKGROUND: Patellar maltracking is a leading cause of patellofemoral pain syndrome (PFPS). The aim of this study was to determine the inter- and intra-rater reliability of a semi-automated program for magnetic resonance imaging (MRI) based patellofemoral kinematics. METHODS: Sixteen subjects (10 with PFPS [mean age 32.3; SD 5.2; eight females] and six controls without PFPS 19 [mean age 28.6; SD 2.8; three females]) participated in the study. One set of T2-weighted, fat-saturated fast spin-echo (FSE) MRIs were acquired from each subject in full extension and 30° of knee flexion...
January 2016: Knee
Toby O Smith, Benjamin T Drew, Toby H Meek, Allan B Clark
BACKGROUND: Patellofemoral pain syndrome (PFPS) is a painful musculoskeletal condition, which is characterised by knee pain located in the anterior aspect (front) and retropatellar region (behind) of the knee joint. Various non-operative interventions are suggested for the treatment of this condition. Knee orthoses (knee braces, sleeves, straps or bandages) are worn over the knee and are thought to help reduce knee pain. They can be used in isolation or in addition to other treatments such as exercise or non-steroidal anti-inflammatory medications...
2015: Cochrane Database of Systematic Reviews
Christopher Plastaras, Zack McCormick, Cayli Nguyen, Monica Rho, Susan Hillary Nack, Dan Roth, Ellen Casey, Kevin Carneiro, Andrew Cucchiara, Joel Press, Jim McLean, Franklin Caldera
BACKGROUND: The current literature indicates that hip abduction weakness in female patients is associated with ipsilateral patellofemoral pain syndrome (PFPS) as part of the weaker hip abductor complex. Thus, it has been suggested that clinicians should consider screening female athletes for hip strength asymmetry to identify those at risk of developing PFPS to prevent the condition. However, no study to date has demonstrated that hip strength asymmetry exists in the early stages of PFPS...
January 2016: American Journal of Sports Medicine
Mohammad Sadegh Ghasemi, Naser Dehghan
BACKGROUND: Patellofemoral pain syndrome (PFPS) is one of the most common disorders of the knee. Conservative approaches, as well as surgery, can decrease pain and the syndrome's progress effectively. OBJECTIVE: The aim of this study was to determine the effectiveness of neoprene palumbo orthosis (NPO) and Genu direxa stable orthosis (GDSO) on pain and the activities of daily living (ADL). METHODS: Thirty patients (males, ages 18 to 40) participated in this randomized blinded clinical trial...
October 2015: Electronic Physician
Ping Miao, Yi Xu, Cuihuan Pan, Hao Liu, Chuhuai Wang
BACKGROUND: The purpose was to investigate the effect of double-leg semisquat with hip adduction on the activation of vastus medialis oblique (VMO) and vastus lateralis (VL) in patients with patellofemoral pain syndrome (PFPS). METHODS: Thirty patients with PFPS were designated to the study group, while 30 healthy matched subjects were enrolled in the control group. The activation of VL and VMO was recorded with surface electromyography (EMG) during double-leg semisquat (DS) and double-leg semisquat with hip adduction (DS-HA)...
2015: BMC Musculoskeletal Disorders
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