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https://www.readbyqxmd.com/read/29054353/the-rate-of-radial-head-prosthesis-removal-or-revision-a-systematic-review-and-meta-analysis
#1
Amir R Kachooei, Aslan Baradaran, Mohammad H Ebrahimzadeh, C Niek van Dijk, Neal Chen
PURPOSE: We conducted a meta-analysis and systematic review with the primary objective to determine the overall incidence of radial head prosthesis removal or revision. Our secondary objectives addressed the incidence of removal or revision based on the type of prosthesis fixation (cemented, uncemented smooth stem, uncemented press-fit), material (metal, Vitallium, titanium, pyrocarbon), and design (short vs long stem and monopolar vs bipolar), and the reasons for prosthetic removal or revision...
October 18, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29051537/microarray-gene-expression-of-periosteum-in-spontaneous-bone-regeneration-of-mandibular-segmental-defects
#2
Zheyi Li, Juli Pan, Jinling Ma, Zhen Zhang, Yuxing Bai
Spontaneous bone regeneration could occur to reestablish mandibular bony continuity in patients who underwent partial or total mandibulectomy for tumors with periosteum-preserving. However, scarce data is available related to the precise role of periosteum in this bone regeneration. Therefore we aimed to investigate the gene expression of periosteum that were involved in the mandibular bone regeneration. Mandibular segmental defects were created in six mini-pigs with periosteum preserved. The periosteum of defects and control site were harvested at 1 and 2 weeks...
October 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29050162/-two-stage-total-hip-arthroplasty-using-an-antibiotic-loaded-cement-spacer-for-infected-internal-fixation-of-hip-fractures
#3
X Li, M Ni, H Li, J L Song, X G Song, J Fu, K Liu, B Z Yu, J Y Chen
Objective: To evaluate the application and clinical results of two-stage total hip arthroplasty in the treatment of the deep hip infection following the internal fixation of hip fractures. Methods: From May 2007 to November 2014, 21 patients with active hip infection secondary to internal fixation of hip fractures were treated with two-stage total hip arthroplasty using a temporary antibiotic-loaded cement spacers. Of 21 cases, 15 were males and 6 were females, aged from 27 to 64 years (mean, 45); there are 18 cases of femoral neck fractures and 3 cases of intertrochanteric fractures...
October 10, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29044619/variation-in-crocodilian-dorsal-scute-organization-and-geometry-with-a-discussion-of-possible-functional-implications
#4
Lauren T English
Dermal ossifications, including osteoderms, are present in many vertebrates and are frequently interpreted as a defense against predators. Nevertheless, osteoderms remain ubiquitous in adult crocodilians while being absent in hatchlings, even though adults rarely experience predation. In other biological systems, increased variation, particularly fluctuating asymmetry, have proven useful for identifying biological structures likely to have evolved under relaxed selection, which in turn may inform their function...
October 17, 2017: Journal of Morphology
https://www.readbyqxmd.com/read/29044618/ultrasonographic-screening-for-subclinical-osteochondrosis-of-the-femoral-trochlea-in-foals-28-166-days-old-a-prospective-farm-study
#5
G Martel, D Crowley, J Olive, J Halley, S Laverty
BACKGROUND: Extensive osteochondritis dissecans (OCD) lesions of the lateral ridge of the trochlea of the femur (LRTF), the most common OCD- affected site in the stifle, have a poor outcome with surgical debridement and can be career ending. The early detection of osteochondrosis lesions and their conservative management holds the promise to enhance outcome. We hypothesise that ultrasonography is a valuable field screening tool to detect and monitor early subclinical LRTF osteochondrosis...
October 17, 2017: Equine Veterinary Journal
https://www.readbyqxmd.com/read/29044593/patterns-of-chondrification-and-ossification-in-the-skull-of-graptemys-pseudogeographica-the-false-map-turtle-emydidae
#6
Sharon C Danielson, Christopher A Sheil
Patterns of ossification and chondrification are well-described for several species of turtles, but details of the chondrocranial anatomy are known for only a handful of species. Cleared and double-stained embryos of Graptemys pseudogeographica were used to examine the fully formed chondrocranium and the formation, chondrification, and ossification of the cranium. The chondrocranium of G. pseudogeographica possesses an unusually large, irregularly shaped foramen epiphaniale that is joined with the fenestra olfactoria...
October 17, 2017: Journal of Morphology
https://www.readbyqxmd.com/read/29039630/impairment-of-the-chondrogenic-phase-of-endochondral-ossification-in-vivo-by-inhibition-of-cyclooxygenase-2
#7
M P Janssen, M M Caron, B van Rietbergen, D A Surtel, L W van Rhijn, T J Welting, P J Emans
Many studies have reported on the effects of cyclooxygenase-2 (COX-2) inhibition on osteogenesis. However, far less is known about the effects of COX-2 inhibition on chondrogenic differentiation. Previous studies conducted by our group show that COX-2 inhibition influences in vitro chondrogenic differentiation. Importantly, this might have consequences on endochondral ossification processes occurring in vivo, such as bone fracture healing, growth plate development and ectopic generation of cartilage. The goal of our study was to investigate, in vivo, the effect of COX-2 inhibition by celecoxib on the cartilaginous phase of three different endochondral ossification scenarios...
October 17, 2017: European Cells & Materials
https://www.readbyqxmd.com/read/29038962/a-comparative-study-between-traditional-fixation-with-miniplates-and-modified-lag-screws-for-the-treatment-of-mandibular-fractures
#8
Ana Rocío García Carricondo, Francisco Javier Quesada Bravo, Fernando Espín Gálvez, Tesifón Parrón Carreño, Raquel Alarcón Rodriguez
OBJECTIVES: The objective of this study is to investigate two internal fixation surgical techniques for mandibular fractures in order to compare modified lag screw techniques with standard miniplates. MATERIALS AND METHODS: This is an observational prospective study. Three hundred eighteen patients were operated on for mandibular fractures. The patients were divided into two groups according to the type of surgical technique used: modified lag screws (155 patients) and traditional miniplates (163 patients)...
October 16, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29038780/pulmonary-ossification-and-microlithiasis-in-a-bitch-with-multicentric-mammary-tumors
#9
Mahir A G Kubba
Microliths and ossification were found in the lungs of a 12-year-old bitch suffering from compound mammary gland tumor which has disseminated in the inguinal lymph node glands and the lungs. Pulmonary ossification appeared grossly as irregular stony sharp particles which infiltrated the lung tissue and were readily recognizable from under the pleura as grayish sharp protruding particles. Microscopic examination revealed the existence of intra-alveolar single or multilobular particles of ossification which are formed of lamellated osseous substance with osteocytes in lacunae...
2017: Open veterinary journal
https://www.readbyqxmd.com/read/29036029/-anterior-skull-base-and-pericranial-flap-ossification-after-frontofacial-monobloc-advancement
#10
Anne Morice, Giovanna Paternoster, Agnès Ostertag, Syril James, Martine Cohen-Solal, Roman H Khonsari, Eric Arnaud
BACKGROUND: Frontofacial monobloc advancement (FFMBA) creates a communication between the anterior cranial fossa and nasal cavities. To tackle this issue, trans-orbital pericranial pedicled flaps (PF) are routinely performed in our center. This study aimed to assess the post-operative ossification of the anterior skull base and PF following FFMBA, and to identify factors influencing this ossification. METHODS: Measurements of the skull base only (SB) and of the ossified PF together with the SB (SB-OPF) were performed on CT scans at the naso-frontal (NF) and the naso-ethmoïdo-frontal (NEF) junctions...
October 12, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29033382/clinical-pathological-correlations-in-three-patients-with-fibrodysplasia-ossificans-progressiva
#11
Kelly L Wentworth, Katherine Bigay, Tea V Chan, Jennifer P Ho, Blanca M Morales, Joseph Connor, Erin Brooks, M Shahriar Salamat, Henry Charles Sanchez, Geoffrey Wool, Robert J Pignolo, Frederick S Kaplan, Edward C Hsiao
OBJECTIVE: Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare genetic disorder in which heterotopic bone forms in the soft tissues. This often occurs in response to injury or inflammation, leading to joint immobilization and significant disability. There are currently no definitive treatment options for this devastating disease. Although the most dramatic phenotype in FOP is the episodic and progressive heterotopic ossification, patients report a number of symptoms that affect other organ systems...
October 12, 2017: Bone
https://www.readbyqxmd.com/read/29032901/bosworth-and-modified-phemister-techniques-revisited-a-comparison-of-intraarticular-vs-extraarticular-fixation-methods-in-the-treatment-of-acute-rockwood-type-iii-acromioclavicular-dislocations
#12
Engin Cetinkaya, Yavuz Arıkan, Kubilay Beng, Harun Mutlu, Merter Yalçınkaya, Onat Üzümcügil
OBJECTIVE: The aim of this study was to compare the long-term clinical and radiological results of Acromioclavicular (AC) fixation with K-wires (the modified Phemister procedure) and Coracoclavicular (CC) fixation with the Bosworth screw in the surgical treatment of Type 3 AC joint dislocations. METHODS: Thirty-two patients with complete set of medical records and who received surgical treatment between September 2005 and January 2009 due to acute Rockwood Type 3 AC joint dislocation and properly attended their follow-ups were retrospectively evaluated...
October 9, 2017: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/29032420/cochlear-implantation-with-the-nucleus-slim-modiolar-electrode-ci532-a-preliminary-experience
#13
Domenico Cuda, Alessandra Murri
To combine the benefits of perimodiolar stimulation with minimal insertion trauma, a thin, pre-curved electrode (CI532) was recently developed by Cochlear Ltd. (Sidney). This array is held straight prior to insertion by an external polymer reloadable sheath that is removed after full electrode insertion. Sixty-seven patients suffering from severe-to-profound sensorineural hearing loss (mean age 42.2 years; mean duration of the hearing loss 19.6 years; mean PTA thresholds at 250-2000 Hz 92.4 dB HL) were implanted with the CI532...
October 14, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29029772/inhibition-of-mammalian-target-of-rapamycin-signaling-with-rapamycin-prevents-trauma-induced-heterotopic-ossification
#14
Ammar T Qureshi, Devaveena Dey, Erin M Sanders, Jonathan G Seavey, Allison M Tomasino, Kaitlyn Moss, Benjamin Wheatley, David Cholok, Shawn Loder, John Li, Benjamin Levi, Thomas A Davis
A pressing clinical need exists for 63% to 65% of combat-wounded service members and 11% to 20% of civilians who develop heterotopic ossification (HO) after blast-related extremity injury and traumatic injuries, respectively. The mammalian target of rapamycin pathway is a central cellular sensor of injury. We evaluated the prophylactic effects of rapamycin, a selective inhibitor of mammalian target of rapamycin signaling, on HO formation in a rat model of blast-related, polytraumatic extremity injury. Rapamycin was administered intraperitoneally daily for 14 days at 0...
October 5, 2017: American Journal of Pathology
https://www.readbyqxmd.com/read/29029440/colorectal-carcinoma-with-osseous-metaplasia
#15
Xibo Liu, Jinghong Xu, Lirong Chen
Osseous metaplasia (OM) is rarely observed in colorectal cancer (incidence < 0.4% in rectal cancer), where it has a non-specific clinical presentation and unknown pathogenesis. Here, we report three cases of colorectal carcinoma with OM and propose a new hypothesis. All three patients (two males and one female) were Chinese and had different sites of colorectal carcinoma with OM: rectum, sigmoid colon, and appendix. The pathologic diagnoses were serrated adenocarcinoma; moderately to poorly differentiated adenocarcinoma with micropapillary carcinoma and cribriform comedo-type adenocarcinoma; and mucinous adenocarcinoma, respectively...
September 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/29027640/the-utility-of-botulinum-toxin-a-in-the-repair-of-distal-biceps-tendon-ruptures
#16
L S Khalil, R A Keller, N Mehran, N E Marshall, K Okoroha, N B Frisch, S P DeSilva
PURPOSE: The purpose of our study is to report the outcomes and complications in patients who underwent distal biceps tendon repair with the use of Botulinum toxin A (BoNT-A) as an adjunct to surgery. METHODS: A retrospective review of 14 patients who underwent 15 distal biceps tendon repairs was performed. All repaired tendons had their correlating muscle bellies injected intraoperatively with a mixture of 100U of BoNT-A and 10 ml of normal saline. Each patient was evaluated for surgical and post-operative complications and followed with Disabilities of the Arm, Shoulder and Hand (DASH) Disability Scores...
October 13, 2017: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/29027187/midterm-results-of-trochanteric-flip-osteotomy-technique-for-management-of-fractures-around-the-hip
#17
Vivek Trikha, Saubhik Das, Arkesh Madegowda, Prabhat Agrawal
INTRODUCTION: In this study, we aimed to investigate safety and efficacy of the trochanteric flip osteotomy with surgical hip dislocation technique in selected displaced acetabular and femoral head fractures with clinico-radiological outcome and potential complications. MATERIALS AND METHODS: We retrospectively reviewed 32 patients from January 2009 to June 2014. Selected displaced acetabular fractures with comminution and/or cranial extension of posterior wall, marginal impaction, intraarticular fragment, femoral head fractures and hip fracture-dislocations were operated by this modified approach of trochanteric flip osteotomy and surgical hip dislocation...
October 9, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/29026147/vascular-endothelial-growth-factor-in-cartilage-development-and-osteoarthritis
#18
Masashi Nagao, John L Hamilton, Ranjan Kc, Agnes D Berendsen, Xuchen Duan, Chan Wook Cheong, Xin Li, Hee-Jeong Im, Bjorn R Olsen
Genome wide studies indicate that vascular endothelial growth factor A (VEGF) is associated with osteoarthritis (OA), and increased VEGF expression correlates with increased disease severity. VEGF is also a chondrocyte survival factor during development and essential for bone formation, skeletal growth and postnatal homeostasis. This raises questions of how the important embryonic and postnatal functions of VEGF can be reconciled with an apparently destructive role in OA. Addressing these questions, we find that VEGF acts as a survival factor in growth plate chondrocytes during development but only up until a few weeks after birth in mice...
October 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29025152/cervical-myelopathy-secondary-to-metallic-irritation-of-the-dura-mater-following-insertion-of-a-spinal-cord-stimulator-in-a-patient-with-ossification-of-posterior-longitudinal-ligament
#19
Jung Eun Kim, Jae Hyuk Yang, Mi Kyoung Lee, Seung Woo Suh, Sung Wook Kang
No abstract text is available yet for this article.
August 29, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29024060/loss-of-dnmt3b-in-chondrocytes-leads-to-delayed-endochondral-ossification-and-fracture-repair
#20
Cuicui Wang, Yousef Abu-Amer, Regis J O'Keefe, Jie Shen
Despite advanced understanding of signaling mediated by local and systemic factors, the role of epigenetic factors in the regulation of bone regeneration remains vague. The DNA methyltransferases (Dnmts) Dnmt3a and Dnmt3b have tissue specific expression patterns and create unique methylation signatures to regulate gene expression. Using a stabilized murine tibia fracture model we find that Dnmt3b is induced early in fracture healing, peaks at 10 days post fracture (dpf), and declines to nearly undetectable levels by 28 dpf...
October 10, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
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