Paul Ford, Michael Kreuter, Kevin K Brown, Wim A Wuyts, Marlies Wijsenbeek, Dominique Israël-Biet, Richard Hubbard, Steven D Nathan, Hilario Nunes, Bjorn Penninckx, Niyati Prasad, Ineke Seghers, Paolo Spagnolo, Nadia Verbruggen, Nik Hirani, Juergen Behr, Robert J Kaner, Toby M Maher
BACKGROUND: There is no standard definition of respiratory-related hospitalisation, a common end-point in idiopathic pulmonary fibrosis (IPF) clinical trials. As diverse aetiologies and complicating comorbidities can present similarly, external adjudication is sometimes employed to achieve standardisation of these events. METHODS: An algorithm for respiratory-related hospitalisation was developed through a literature review of IPF clinical trials with respiratory-related hospitalisation as an end-point...
January 2024: ERJ Open Research