Pavel Osmancik, Barbora Bacova, Marek Hozman, Jitka Pistkova, Veronika Kunstatova, Veronika Sochorova, Petr Waldauf, Sabri Hassouna, Jakub Karch, Jana Vesela, Lukas Poviser, Lucie Znojilova, Vera Filipcova, Klara Benesova, Dalibor Herman
BACKGROUND: Pulsed-field ablation (PFA) represents a new, nonthermal ablation energy for the ablation of atrial fibrillation (AF). Ablation energies producing thermal injury are associated with an inflammatory response, platelet activation, and coagulation activation. OBJECTIVES: This study aimed to compare the systemic response in patients undergoing pulmonary vein isolation (PVI) using pulsed-field and radiofrequency (RF) energy. METHODS: Patients with AF indicated for PVI were enrolled and randomly assigned to undergo PVI using RF (CARTO Smart Touch, Biosense Webster) or pulsed-field (Farapulse, Boston-Scientific) energy...
November 6, 2023: JACC. Clinical Electrophysiology