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https://www.readbyqxmd.com/read/28964283/thyroglossal-duct-cyst-surgery-a-ten-year-single-institution-experience
#1
Justin Ross, Alexander Manteghi, Kimberly Rethy, James Ding, Sri Kiran Chennupati
OBJECTIVE: 1. Review our institution's experience with thyroglossal duct cyst (TGDC) excision. 2. Determine if TGDC recurrence rate is influenced by surgical technique, preoperative infection, or surgeon specialty. METHODS: We conducted a retrospective analysis of patients at a tertiary care children's hospital who underwent excision of neck mass with proven TGDC histopathology from 2005 to 2015. Patient demographics and presentation, preoperative workup, surgeon specialty, procedural details, lesion characteristics, and complication rates including recurrence were evaluated...
October 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28816214/synchronous-malignancies-of-thyroglossal-duct-cyst-and-thyroid-gland
#2
Chinna Naik, Sandip Basu
Malignant involvement of thyroglossal duct cyst is rare, still rarer is the synchronous malignant involvement of the thyroid gland. Although the Sistrunk procedure is often regarded as adequate, controversy exists of the need for an additional total thyroidectomy and radioiodine ablative therapy, the decision of which depends upon the presence of (i) suspicious thyroid gland nodule; (ii) presence of lymphadenopathy; or (iii) a previous history of neck irradiation. We report a 47-year-old woman diagnosed with papillary carcinoma within a recurrent thyroglossal duct cyst with infiltration into surrounding soft tissues and a suspicious thyroid nodule of the left thyroid lobe with no regional lymph node involvement...
March 2017: National Medical Journal of India
https://www.readbyqxmd.com/read/28611468/insights-into-enterotoxigenic-escherichia-coli-diversity-in-bangladesh-utilizing-genomic-epidemiology
#3
Jason W Sahl, Jeticia R Sistrunk, Nabilah Ibnat Baby, Yasmin Begum, Qingwei Luo, Alaullah Sheikh, Firdausi Qadri, James M Fleckenstein, David A Rasko
Enterotoxigenic Escherichia coli (ETEC) cause more than 500,000 deaths each year in the developing world and are characterized on a molecular level by the presence of genes that encode the heat-stable (ST) and/or heat-labile (LT) enterotoxins, as well as surface structures, known as colonization factors (CFs). Genome sequencing and comparative genomic analyses of 94 previously uncharacterized ETEC isolates demonstrated remarkable genomic diversity, with 28 distinct sequence types identified in three phylogenomic groups...
June 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28390616/five-years-experience-with-outpatient-thyroglossal-duct-cyst-surgery
#4
Ana Coelho, Catarina Sousa, Ana Sofia Marinho, Joana Barbosa-Sequeira, João Ribeiro-Castro, Fátima Carvalho, João Moreira-Pinto
OBJECTIVES: Many pediatric surgeons feel uncomfortable doing Sistrunk procedure without drain placement and in an outpatient setting. This study aimed to review our pediatric surgery department's experience in managing thyroglossal duct cyst surgery and to prove feasibility and safety of Sistrunk procedure without drain placement in an outpatient setting. METHODS: A retrospective review was performed of all patients who underwent Sistrunk procedure, between January 2011 and December 2015, in our department...
May 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28348056/analysis-of-shigella-flexneri-resistance-biofilm-formation-and-transcriptional-profile-in-response-to-bile-salts
#5
Kourtney P Nickerson, Rachael B Chanin, Jeticia R Sistrunk, David A Rasko, Peter J Fink, Eileen M Barry, James P Nataro, Christina S Faherty
The Shigella species cause millions of cases of watery or bloody diarrhea each year, mostly in children in developing countries. While many aspects of Shigella colonic cell invasion are known, crucial gaps in knowledge regarding how the bacteria survive, transit, and regulate gene expression prior to infection remain. In this study, we define mechanisms of resistance to bile salts and build on previous research highlighting induced virulence in Shigella flexneri strain 2457T following exposure to bile salts...
June 2017: Infection and Immunity
https://www.readbyqxmd.com/read/28322121/thyroglossal-duct-cyst-carcinoma-a-systematic-review-of-clinical-features-and-outcomes
#6
REVIEW
Hani M Rayess, Ian Monk, Peter F Svider, Amar Gupta, S Naweed Raza, Ho-Sheng Lin
Objective Although thyroglossal duct cysts (TGDCs) are relatively common, malignancies within these lesions are infrequent. As a result, there are no large-scale series describing clinical characteristics. Our objectives were to perform a systematic review of the literature evaluating patient demographics, pathology, management, and prognosis of these patients. Data Sources PubMed, Embase, Cochrane reviews, and Google Scholar were searched for relevant articles. Articles meeting inclusion criteria were reviewed for data detailing epidemiology, treatment, and outcomes...
May 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28293858/thyroglossal-duct-cyst-carcinomas-in-pediatric-patients-report-of-two-cases-with-a-comprehensive-literature-review
#7
Lester D R Thompson, Hannah B Herrera, Sean K Lau
Thyroglossal duct cyst (TGDC) carcinomas are rarely encountered in the pediatric population. The clinical behavior of these tumors in the pediatric setting is unclear and management is not well defined. Two cases of pediatric thyroglossal duct cyst carcinoma were identified in a review of all thyroglossal duct cysts diagnosed over a ten year period. These two cases were analyzed along with 57 cases of thyroglossal duct cyst carcinoma affecting patients less than 21 years of age compiled from the English literature...
March 14, 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/28284788/application-of-trotter-approach-for-large-intralingual-thyroglossal-duct-cyst-in-an-88-year-old-patient
#8
Richard L Arden, Laura K Miller
Thyroglossal duct cysts (TDCs) are the most common congenital cyst formations in the neck, typically occurring at midline infrahyoid positions in younger patients. Traditional management has used the Sistrunk procedure to minimize recurrence rates. Reports on elderly patients are sparse, and currently only 16 cases have been reported in patients older than 70 years and 4 patients older than 80 years. This report describes the oldest known patient with TDC who had a purely intralingual location requiring a Trotter approach and a Sistrunk procedure for symptomatic management...
September 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28273922/the-role-of-super-atom-molecular-orbitals-in-doped-fullerenes-in-a-femtosecond-intense-laser-field
#9
Hui Xiong, Benoit Mignolet, Li Fang, Timur Osipov, Thomas J A Wolf, Emily Sistrunk, Markus Gühr, Francoise Remacle, Nora Berrah
The interaction of gas phase endohedral fullerene Ho3N@C80 with intense (0.1-5 × 10(14) W/cm(2)), short (30 fs), 800 nm laser pulses was investigated. The power law dependence of Ho3N@C80(q+), q = 1-2, was found to be different from that of C60. Time-dependent density functional theory computations revealed different light-induced ionization mechanisms. Unlike in C60, in doped fullerenes, the breaking of the cage spherical symmetry makes super atomic molecular orbital (SAMO) states optically active...
December 2017: Scientific Reports
https://www.readbyqxmd.com/read/28270939/simultaneous-papillary-carcinoma-in-thyroglossal-duct-cyst-and-thyroid
#10
Gustavo Cancela E Penna, Henrique Gomes Mendes, Adele O Kraft, Cynthia Koeppel Berenstein, Bernardo Fonseca, Wagner José Martorina, Andreise Laurian N R de Souza, Gustavo Meyer de Moraes, Kamilla Maria Araújo Brandão Rajão, Bárbara Érika Caldeira Araújo Sousa
Thyroglossal duct cyst (TDC) is a cystic expansion of a remnant of the thyroglossal duct tract. Carcinomas in the TDC are extremely rare and are usually an incidental finding after the Sistrunk procedure. In this report, an unusual case of a 36-year-old woman with concurrent papillary thyroid carcinoma arising in the TDC and on the thyroid gland is presented, followed by a discussion of the controversies surrounding the possible origins of a papillary carcinoma in the TDC, as well as the current management options...
2017: Case Reports in Endocrinology
https://www.readbyqxmd.com/read/28239588/a-decade-of-experience-of-management-of-thyroglossal-duct-cyst-in-a-tertiary-care-hospital-differentiation-between-children-and-adults
#11
Shakeel Uz Zaman, Mubasher Ikram, Mohammad Sohail Awan, Nabeel Humayun Hassan
Variations in thyroglossal duct cysts (TGDCs) between children and adult are mentioned very little in literature. The lesion mostly found in children but adult population also possesses this anomaly. The aim of this study was to determine the differences in clinical presentations and surgical outcomes of TGDC between children and adults. A retrospective chart review of all patients with TGDCs managed in our hospital from July 2004 to June 2014. All records were reviewed for age, sex, location of cyst in neck and with relation to hyoid bone, size, postoperative complication and recurrence rates...
March 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28235652/ultrasonographic-findings-of-thyroglossal-duct-papillary-carcinoma-a-case-report
#12
Chonticha Srivanitchapoom, Pichit Sittitrai, Kedsaraporn Yata, Piyadara Khongpiboonkit
INTRODUCTION: Reports on thyroglossal duct cyst carcinoma (TGDCCa) are rare, occurring in approximately 1% of thyroglossal duct cyst (TGDC) cases. The origin and treatment of carcinoma arising in TGDC are controversy. PRESENTATION OF CASE: A 38-year-old woman presented with a midline neck mass at the thyrohyoid level for 3 years. Ultrasound revealed a 2.4cm cystic mass with a solid mural component and microcalcification. A small right thyroid nodule was also detected...
2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28156123/thyroglossal-duct-cyst-abbreviated-review-and-case-report
#13
Nicholas J Fujii, Tanya M Gibson, Keerthana M Satheesh, Charles M Cobb
The thyroglossal duct cyst (TGDC) is the most common developmental cyst of the neck. The cyst typically occurs along the midline of the neck on the ventral surface. Malignant transformation is rare and can be diagnosed only after histologic examination of a biopsy specimen. This article presents a brief, focused narrative review, which includes a discussion of successful treatment of a TGDC, and a single case report that describes a Sistrunk-like procedure.
February 2017: Compendium of Continuing Education in Dentistry
https://www.readbyqxmd.com/read/27957639/treatment-efficacy-and-safety-of-ethanol-ablation-for-thyroglossal-duct-cysts-a-comparison-with-surgery
#14
Mi Sun Chung, Jung Hwan Baek, Jeong Hyun Lee, Young Jun Choi, Jong Ho Yoon, Soon Yuhl Nam, Seong Chul Kim, Jin Yong Sung, Seon Mi Baek, Dong Gyu Na
OBJECTIVE: To compare the efficacy and safety of ethanol ablation (EA) for thyroglossal duct cyst (TGDC) against surgery. METHODS: This study included 345 patients (289, surgery; 56, EA) treated for TGDC at four institutions between May 2005 and June 2014. Surgery (whole surgery and Sistrunk operation which is the current standard surgical method) and EA were compared with respect to the treatment failure and complication rates. The cost of EA and surgery was also compared...
July 2017: European Radiology
https://www.readbyqxmd.com/read/27833882/adult-thyroglossal-duct-carcinoma-of-thyroid-epithelial-origin-a-retrospective-observational-study
#15
Rahim Akram, Joseph J Wiltshire, Jonathan Wadsley, Sabapathy P Balasubramanian
Thyroglossal duct or cyst carcinoma (TGDCCa) is uncommon. Current treatments follow those of thyroid cancer but controversy exists over the extent of thyroid and lymph node surgery. Our aim was to study the presentation, treatment strategies and clinical outcomes in patients presenting with TGDCCa. Of 637 patients diagnosed with thyroid cancer over 15-years, 4 patients (0.6 %) with TGDCCa were identified. Two patients were diagnosed outside this time period. Details of demographics, presentation, diagnosis, management and outcomes of all 6 patients were reviewed...
December 2016: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/27794246/incidental-papillary-thyroid-carcinoma-in-thyroglossal-duct-cyst-case-report
#16
Ana Karen Lira Medina, Eliseo Fernandez Berdeal, Ernesto Bernal Cisneros, Rebeca Betancourt Galindo, Pamela Frigerio
INTRODUCTION: The thyroglossal cyst is found in 7% of the population and the incidental papillary thyroid carcinoma in thyroglossal cyst is a rare entity with an incidence 1 to 2%. The clinical presentation is indistinguishable from a benign lesion and the histopathological postoperative study defines the diagnosis. Papillary carcinomas have favorable prognosis and cervical or distant metastases are rare. There is now a consensus on the indication of total thyroidectomy, radioablation with iodine and/or suppressive therapy with levothyroxine after being removed surgically [1-3] (Patrucco et al...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27714447/alpha-defensin-novel-synovial-fluid-biomarker-for-the-diagnosis-of-periprosthetic-joint-infection
#17
REVIEW
Jakrapun Pupaibool, Eric J Fulnecky, Robert L Swords, William W Sistrunk, Alastair D Haddow
PURPOSE: Periprosthetic joint infection (PJI) continues to be a significant complication after total joint arthroplasty. Diagnosis of PJI can be challenging and elusive in the absence of a gold standard. This purpose of this article is to review the current evidence on the utility of serum and synovial fluid biomarkers to help aid in the diagnosis of PJI with focusing on synovial fluid alpha-defensin. METHODS: Articles and data for this review were identified by searches of PubMed and Ovid MEDLINE up to June 1, 2016...
December 2016: International Orthopaedics
https://www.readbyqxmd.com/read/27704385/thyroglossal-duct-cyst-carcinomas-a-clinicopathologic-series-of-22-cases-with-staging-recommendations
#18
Lester D R Thompson, Hannah B Herrera, Sean K Lau
Carcinomas arising from thyroglossal duct remnant cysts (TGDCs) are rare, without well-defined management and staging criteria. All TGDCs (n = 685) diagnosed between 2005 and 2015 were retrospectively reviewed, with 22 carcinomas identified (3.2 % incidence). Twenty-two patients (17 females, 5 males), aged 12-64 years (mean 39.9 years; median 39 years) were identified. An anterior, superior midline neck mass was the presenting symptom in all patients. A cancer diagnosis [all papillary thyroid carcinoma (PTC)] was made after the Sistrunk procedure (SP), with a Bethesda Category V or VI classification preoperatively by fine needle aspiration in 5 of 12 cases tested...
June 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/27606652/-experience-in-thyroglossal-duct-pathology-clinical-case-series
#19
Patricio Cieri, Julia E Udaquiola, Santiago E Calello, Daniel H Libero
The thyroglossal duct cyst pathology represents the second cause of bening cervical anomalies in childhood. Diagnosis is mainly clinical. Sistrunk (1920) proposed a surgical technique that is still considered the gold standard for definitive treatment of this condition. A retrospective study was made including patients who underwent surgery for thyroglossal duct cyst pathology in our department between June 2008 and August 2015. In this period, we performed 54 procedures in 45 patients (39 primary cases). Median age was 4...
October 1, 2016: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/27492432/bilateral-areolar-endoscopic-sistrunk-operation-a-novel-technique-for-thyroglossal-duct-cyst-surgery
#20
Angkoon Anuwong, Pornpeera Jitpratoom, Thanyawat Sasanakietkul
BACKGROUND: Sistrunk operation of the thyroglossal duct is a procedure for the removal of a cyst, the middle part of the hyoid bone and tract towards the foramen caecum. Unavoidably, this procedure results in a scar on the skin in the neck area. By performing a bilateral areolar endoscopic Sistrunk operation, this study is the first to develop a procedure that can solve the aesthetic problem. This operation results in both an excellent cosmetic result and the successful treatment of TGDC...
April 2017: Surgical Endoscopy
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