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https://www.readbyqxmd.com/read/28322121/thyroglossal-duct-cyst-carcinoma-a-systematic-review-of-clinical-features-and-outcomes
#1
Hani M Rayess, Ian Monk, Peter F Svider, Amar Gupta, S Naweed Raza, Ho-Sheng Lin
Objective Although thyroglossal duct cysts (TGDCs) are relatively common, malignancies within these lesions are infrequent. As a result, there are no large-scale series describing clinical characteristics. Our objectives were to perform a systematic review of the literature evaluating patient demographics, pathology, management, and prognosis of these patients. Data Sources PubMed, Embase, Cochrane reviews, and Google Scholar were searched for relevant articles. Articles meeting inclusion criteria were reviewed for data detailing epidemiology, treatment, and outcomes...
March 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28293858/thyroglossal-duct-cyst-carcinomas-in-pediatric-patients-report-of-two-cases-with-a-comprehensive-literature-review
#2
Lester D R Thompson, Hannah B Herrera, Sean K Lau
Thyroglossal duct cyst (TGDC) carcinomas are rarely encountered in the pediatric population. The clinical behavior of these tumors in the pediatric setting is unclear and management is not well defined. Two cases of pediatric thyroglossal duct cyst carcinoma were identified in a review of all thyroglossal duct cysts diagnosed over a ten year period. These two cases were analyzed along with 57 cases of thyroglossal duct cyst carcinoma affecting patients less than 21 years of age compiled from the English literature...
March 14, 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/28284788/application-of-trotter-approach-for-large-intralingual-thyroglossal-duct-cyst-in-an-88-year-old-patient
#3
Richard L Arden, Laura K Miller
Thyroglossal duct cysts (TDCs) are the most common congenital cyst formations in the neck, typically occurring at midline infrahyoid positions in younger patients. Traditional management has used the Sistrunk procedure to minimize recurrence rates. Reports on elderly patients are sparse, and currently only 14 cases have been reported in patients older than 70 years and 4 patients older than 80 years. This report describes the oldest known patient with TDC who had a purely intralingual location requiring a Trotter approach and a Sistrunk procedure for symptomatic management...
February 17, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28273922/the-role-of-super-atom-molecular-orbitals-in-doped-fullerenes-in-a-femtosecond-intense-laser-field
#4
Hui Xiong, Benoit Mignolet, Li Fang, Timur Osipov, Thomas J A Wolf, Emily Sistrunk, Markus Gühr, Francoise Remacle, Nora Berrah
The interaction of gas phase endohedral fullerene Ho3N@C80 with intense (0.1-5 × 10(14) W/cm(2)), short (30 fs), 800 nm laser pulses was investigated. The power law dependence of Ho3N@C80(q+), q = 1-2, was found to be different from that of C60. Time-dependent density functional theory computations revealed different light-induced ionization mechanisms. Unlike in C60, in doped fullerenes, the breaking of the cage spherical symmetry makes super atomic molecular orbital (SAMO) states optically active...
December 2017: Scientific Reports
https://www.readbyqxmd.com/read/28270939/simultaneous-papillary-carcinoma-in-thyroglossal-duct-cyst-and-thyroid
#5
Gustavo Cancela E Penna, Henrique Gomes Mendes, Adele O Kraft, Cynthia Koeppel Berenstein, Bernardo Fonseca, Wagner José Martorina, Andreise Laurian N R de Souza, Gustavo Meyer de Moraes, Kamilla Maria Araújo Brandão Rajão, Bárbara Érika Caldeira Araújo Sousa
Thyroglossal duct cyst (TDC) is a cystic expansion of a remnant of the thyroglossal duct tract. Carcinomas in the TDC are extremely rare and are usually an incidental finding after the Sistrunk procedure. In this report, an unusual case of a 36-year-old woman with concurrent papillary thyroid carcinoma arising in the TDC and on the thyroid gland is presented, followed by a discussion of the controversies surrounding the possible origins of a papillary carcinoma in the TDC, as well as the current management options...
2017: Case Reports in Endocrinology
https://www.readbyqxmd.com/read/28239588/a-decade-of-experience-of-management-of-thyroglossal-duct-cyst-in-a-tertiary-care-hospital-differentiation-between-children-and-adults
#6
Shakeel Uz Zaman, Mubasher Ikram, Mohammad Sohail Awan, Nabeel Humayun Hassan
Variations in thyroglossal duct cysts (TGDCs) between children and adult are mentioned very little in literature. The lesion mostly found in children but adult population also possesses this anomaly. The aim of this study was to determine the differences in clinical presentations and surgical outcomes of TGDC between children and adults. A retrospective chart review of all patients with TGDCs managed in our hospital from July 2004 to June 2014. All records were reviewed for age, sex, location of cyst in neck and with relation to hyoid bone, size, postoperative complication and recurrence rates...
March 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28235652/ultrasonographic-findings-of-thyroglossal-duct-papillary-carcinoma-a-case-report
#7
Chonticha Srivanitchapoom, Pichit Sittitrai, Kedsaraporn Yata, Piyadara Khongpiboonkit
INTRODUCTION: Reports on thyroglossal duct cyst carcinoma (TGDCCa) are rare, occurring in approximately 1% of thyroglossal duct cyst (TGDC) cases. The origin and treatment of carcinoma arising in TGDC are controversy. PRESENTATION OF CASE: A 38-year-old woman presented with a midline neck mass at the thyrohyoid level for 3 years. Ultrasound revealed a 2.4cm cystic mass with a solid mural component and microcalcification. A small right thyroid nodule was also detected...
February 13, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28156123/thyroglossal-duct-cyst-abbreviated-review-and-case-report
#8
Nicholas J Fujii, Tanya M Gibson, Keerthana M Satheesh, Charles M Cobb
The thyroglossal duct cyst (TGDC) is the most common developmental cyst of the neck. The cyst typically occurs along the midline of the neck on the ventral surface. Malignant transformation is rare and can be diagnosed only after histologic examination of a biopsy specimen. This article presents a brief, focused narrative review, which includes a discussion of successful treatment of a TGDC, and a single case report that describes a Sistrunk-like procedure.
February 2017: Compendium of Continuing Education in Dentistry
https://www.readbyqxmd.com/read/27957639/treatment-efficacy-and-safety-of-ethanol-ablation-for-thyroglossal-duct-cysts-a-comparison-with-surgery
#9
Mi Sun Chung, Jung Hwan Baek, Jeong Hyun Lee, Young Jun Choi, Jong Ho Yoon, Soon Yuhl Nam, Seong Chul Kim, Jin Yong Sung, Seon Mi Baek, Dong Gyu Na
OBJECTIVE: To compare the efficacy and safety of ethanol ablation (EA) for thyroglossal duct cyst (TGDC) against surgery. METHODS: This study included 345 patients (289, surgery; 56, EA) treated for TGDC at four institutions between May 2005 and June 2014. Surgery (whole surgery and Sistrunk operation which is the current standard surgical method) and EA were compared with respect to the treatment failure and complication rates. The cost of EA and surgery was also compared...
December 12, 2016: European Radiology
https://www.readbyqxmd.com/read/27833882/adult-thyroglossal-duct-carcinoma-of-thyroid-epithelial-origin-a-retrospective-observational-study
#10
Rahim Akram, Joseph J Wiltshire, Jonathan Wadsley, Sabapathy P Balasubramanian
Thyroglossal duct or cyst carcinoma (TGDCCa) is uncommon. Current treatments follow those of thyroid cancer but controversy exists over the extent of thyroid and lymph node surgery. Our aim was to study the presentation, treatment strategies and clinical outcomes in patients presenting with TGDCCa. Of 637 patients diagnosed with thyroid cancer over 15-years, 4 patients (0.6 %) with TGDCCa were identified. Two patients were diagnosed outside this time period. Details of demographics, presentation, diagnosis, management and outcomes of all 6 patients were reviewed...
December 2016: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/27794246/incidental-papillary-thyroid-carcinoma-in-thyroglossal-duct-cyst-case-report
#11
Ana Karen Lira Medina, Eliseo Fernandez Berdeal, Ernesto Bernal Cisneros, Rebeca Betancourt Galindo, Pamela Frigerio
INTRODUCTION: The thyroglossal cyst is found in 7% of the population and the incidental papillary thyroid carcinoma in thyroglossal cyst is a rare entity with an incidence 1 to 2%. The clinical presentation is indistinguishable from a benign lesion and the histopathological postoperative study defines the diagnosis. Papillary carcinomas have favorable prognosis and cervical or distant metastases are rare. There is now a consensus on the indication of total thyroidectomy, radioablation with iodine and/or suppressive therapy with levothyroxine after being removed surgically [1-3] (Patrucco et al...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27714447/alpha-defensin-novel-synovial-fluid-biomarker-for-the-diagnosis-of-periprosthetic-joint-infection
#12
Jakrapun Pupaibool, Eric J Fulnecky, Robert L Swords, William W Sistrunk, Alastair D Haddow
PURPOSE: Periprosthetic joint infection (PJI) continues to be a significant complication after total joint arthroplasty. Diagnosis of PJI can be challenging and elusive in the absence of a gold standard. This purpose of this article is to review the current evidence on the utility of serum and synovial fluid biomarkers to help aid in the diagnosis of PJI with focusing on synovial fluid alpha-defensin. METHODS: Articles and data for this review were identified by searches of PubMed and Ovid MEDLINE up to June 1, 2016...
October 7, 2016: International Orthopaedics
https://www.readbyqxmd.com/read/27704385/thyroglossal-duct-cyst-carcinomas-a-clinicopathologic-series-of-22-cases-with-staging-recommendations
#13
Lester D R Thompson, Hannah B Herrera, Sean K Lau
Carcinomas arising from thyroglossal duct remnant cysts (TGDCs) are rare, without well-defined management and staging criteria. All TGDCs (n = 685) diagnosed between 2005 and 2015 were retrospectively reviewed, with 22 carcinomas identified (3.2 % incidence). Twenty-two patients (17 females, 5 males), aged 12-64 years (mean 39.9 years; median 39 years) were identified. An anterior, superior midline neck mass was the presenting symptom in all patients. A cancer diagnosis [all papillary thyroid carcinoma (PTC)] was made after the Sistrunk procedure (SP), with a Bethesda Category V or VI classification preoperatively by fine needle aspiration in 5 of 12 cases tested...
October 4, 2016: Head and Neck Pathology
https://www.readbyqxmd.com/read/27606652/-experience-in-thyroglossal-duct-pathology-clinical-case-series
#14
Patricio Cieri, Julia E Udaquiola, Santiago E Calello, Daniel H Libero
The thyroglossal duct cyst pathology represents the second cause of bening cervical anomalies in childhood. Diagnosis is mainly clinical. Sistrunk (1920) proposed a surgical technique that is still considered the gold standard for definitive treatment of this condition. A retrospective study was made including patients who underwent surgery for thyroglossal duct cyst pathology in our department between June 2008 and August 2015. In this period, we performed 54 procedures in 45 patients (39 primary cases). Median age was 4...
October 1, 2016: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/27492432/bilateral-areolar-endoscopic-sistrunk-operation-a-novel-technique-for-thyroglossal-duct-cyst-surgery
#15
Angkoon Anuwong, Pornpeera Jitpratoom, Thanyawat Sasanakietkul
BACKGROUND: Sistrunk operation of the thyroglossal duct is a procedure for the removal of a cyst, the middle part of the hyoid bone and tract towards the foramen caecum. Unavoidably, this procedure results in a scar on the skin in the neck area. By performing a bilateral areolar endoscopic Sistrunk operation, this study is the first to develop a procedure that can solve the aesthetic problem. This operation results in both an excellent cosmetic result and the successful treatment of TGDC...
August 4, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27488336/wide-anterior-neck-dissection-for-management-of-recurrent-thyroglossal-duct-cysts-in-adults
#16
L M O'Neil, D A Gunaratne, A T Cheng, F Riffat
OBJECTIVE: Thyroglossal duct cyst recurrence following resection is attributed to anatomical variability and residual thyroglossal ducts. In adults, thyroglossal duct cyst recurrence is extremely rare and a surgical solution is yet to be well explored. This paper describes our approach to the management of recurrent thyroglossal duct cysts and sinuses in adults using a wide anterior neck dissection. METHOD: A retrospective review was performed to identify adults who underwent a wide anterior neck dissection for recurrent thyroglossal duct cyst management between 1 January 2009 and 1 January 2015...
July 2016: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/27464994/survival-of-the-fittest-how-bacterial-pathogens-utilize-bile-to-enhance-infection
#17
REVIEW
Jeticia R Sistrunk, Kourtney P Nickerson, Rachael B Chanin, David A Rasko, Christina S Faherty
Bacterial pathogens have coevolved with humans in order to efficiently infect, replicate within, and be transmitted to new hosts to ensure survival and a continual infection cycle. For enteric pathogens, the ability to adapt to numerous host factors under the harsh conditions of the gastrointestinal tract is critical for establishing infection. One such host factor readily encountered by enteric bacteria is bile, an innately antimicrobial detergent-like compound essential for digestion and nutrient absorption...
October 2016: Clinical Microbiology Reviews
https://www.readbyqxmd.com/read/27464557/treatment-of-large-thyroglossal-duct-cyst
#18
Germano de Lelis Bezerra Júnior, Leonardo de Freitas Silva, Gabriel Gomes Pimentel, José Rodrigues Laureano Filho, Renato Luiz Maia Nogueira
The thyroglossal duct cyst is the neck congenital abnormality most common in the childhood. Clinically, it shows itself as a solitary neck mass in the region of hyoid bone, it is painless and can be dislocated during de physical examination and tongue protrusion. The most common treatment is its removal through the Sistrunk technique. Patient with diagnosis of thyroglossal duct cyst in neck region with extension to the mouth floor was treated by total surgical removal through intraoral access. The intraoral approach to the treatment of the thyroglossal duct cyst showed itself practicable and permitted the total removal of the lesion with no recurrence signs...
July 26, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27403240/presentation-management-and-outcome-of-thyroglossal-duct-cysts-in-adult-and-pediatric-populations-a-14-year-single-center-experience
#19
Hassan Al-Thani, Ayman El-Menyar, Maryam Al Sulaiti, Jamela El-Mabrok, Khairi Hajaji, Hesham Elgohary, Mohammad Asim, Ibrahim Taha, Abdelhakem Tabeb
OBJECTIVES: A thyroglossal duct cyst (TDC) is a frequent congenital midline anomaly of the neck that usually manifests during the first decade of life. We aimed to describe the presentation, management, and outcome of TDC in pediatric and adult cases. METHODS: A retrospective observational analysis was conducted for all patients diagnosed and treated for TDC between 2000 and 2014 in a single center in Qatar. Data included patients' demographics, presentations, preoperative investigations, anesthesia type, histopathological findings, surgical management, recurrences, and complications...
July 2016: Oman Medical Journal
https://www.readbyqxmd.com/read/27339199/the-extent-of-surgery-in-thyroglossal-cyst-carcinoma
#20
Sohail Bakkar, Marco Biricotti, Gianni Stefanini, Carlo Enrico Ambrosini, Gabriele Materazzi, Paolo Miccoli
PURPOSE: The optimal management of thyroglossal cyst carcinoma, particularly the extent of surgery required is controversial. The aim of this study was to evaluate the need for routinely adding total thyroidectomy to Sistrunk's operation in the management of this condition. METHODS: The clinical records of 19 patients with a diagnosis of thyroglossal cyst carcinoma encountered in an 11-year period (2004-2015) were reviewed. All patients underwent total thyroidectomy in addition to Sistrunk's procedure...
June 23, 2016: Langenbeck's Archives of Surgery
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