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https://www.readbyqxmd.com/read/28944613/propensity-score-matched-all-comers-population-treated-with-ultra-thin-strut-bare-metal-and-sirolimus-probucol-coated-drug-eluting-stents-of-identical-stent-architecture
#1
Florian Krackhardt, Mohd Ali Rosli, Matthias Leschke, André Schneider, Christian Sperling, Tay Mok Heang, Maxime Pons, Pedro Jerónimo Sousa, Behrouz Kherad, Matthias Waliszewski
OBJECTIVE: The objective of this study was to compare the safety and efficacy of a polymer-free sirolimus coated, ultrathin strut drug eluting stent (PF-SES) to its uncoated bare-metal stent (BMS) platform of identical stent architecture. BACKGROUND: Recently published randomized trials comparing BMS to DES with a focus on shortened dual-antiplatelet therapy reported incidences of stent thrombosis (ST) and bleeding complications (LEADERS FREE) in favor of drug eluting stents (DES)...
September 25, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28940292/different-patients-different-outcomes-a-case-control-study-of-spontaneous-coronary-artery-dissection-versus-acute-coronary-syndrome
#2
Heath Adams, Elizabeth Paratz, Jithendra Somaratne, Jamie Layland, Andrew Burns, Sonny Palmer, Andrew MacIsaac, Robert Whitbourn
INTRODUCTION: There is progressive interest worldwide in spontaneous coronary artery dissection (SCAD). To identify a SCAD cohort and compare risk factors, presentation, and management outcomes compared to acute coronary syndrome (ACS) matched controls. METHODS: Retrospective analysis was performed from 2000 to 2015. Clinical data included a neuropsychiatric history, with management and clinical outcomes assessed at 12 months. Patients were matched on a 1:3 case-control basis according to type of ACS...
September 20, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/28939719/clinical-characteristics-and-management-of-coronary-artery-perforations-a-single-center-11-year-experience-and-practical-overview
#3
Miguel E Lemmert, Rutger J van Bommel, Roberto Diletti, Jeroen M Wilschut, Peter P de Jaegere, F Zijlstra, Joost Daemen, Nicolas M Van Mieghem
BACKGROUND: Coronary artery perforation (CAP) is a potentially lethal complication of percutaneous coronary intervention. We report on the incidence, clinical characteristics, and management of iatrogenic coronary perforations based on an 11-year single-center experience. METHODS AND RESULTS: From February 9, 2005, through November 20, 2016, 150 CAP cases were identified from our percutaneous coronary intervention database of 21 212 procedures (0.71%). Mean age of CAP patients was 66±11 years, and 62...
September 22, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28938644/intravascular-ultrasound-guidance-in-drug-eluting-stents-implantation-a-meta-analysis-and-trial-sequential-analysis-of-randomized-controlled-trials
#4
Cheng Qian, Hong Feng, Jianlei Cao, Guangyu Zhang, Yanggan Wang
OBJECTIVE: Previous evidence suggested that intravascular ultrasound (IVUS) guidance could improve outcomes after drug-eluting stents (DES) placement, largely driven by data from observational studies. We, therefore, performed a meta-analysis and trial sequential analysis of randomized controlled trials to overcome this limitation. RESULTS: The retrieval process yielded 7 RCTs with 3,192 patients. Compared to the angiography guidance, IVUS-guided DES implantation was associated with a significant reduction in the major adverse cardiac events (MACE) (OR 0...
August 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/28935075/6-month-clinical-and-angiographic-outcomes-of-a-novel-radiopaque-sirolimus-eluting-bioresorbable-vascular-scaffold-the-fantom-ii-study
#5
Alexandre Abizaid, Didier Carrié, Norbert Frey, Matthias Lutz, Joachim Weber-Albers, Darius Dudek, Bernard Chevalier, Shu-Chuan Weng, Ricardo A Costa, Jeffrey Anderson, Gregg W Stone
OBJECTIVES: The purpose of this study was to evaluate the outcomes of the novel Fantom coronary bioresorbable scaffold at 6 months. BACKGROUND: The Fantom sirolimus-eluting bioresorbable scaffold incorporates a unique proprietary iodinated, polycarbonate copolymer of tyrosine analogs that is radiopaque, with thin struts (125 μm) that facilitate device delivery and precise target lesion treatment. METHODS: The 6-month outcomes and performance of the Fantom scaffold were evaluated in 117 patients with single de novo native coronary artery lesions of length ≤20 mm and reference vessel diameter 2...
September 25, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28934715/stercoral-perforation-of-the-rectosigmoid-colon-due-to-chronic-constipation-a-case-report
#6
Mustafa Fevzi Celayir, Hakan Mustafa Köksal, Mehmet Uludag
INTRODUCTION: Chronic constipation is very common in elderly patients. As a result of this situation fecaloma is also frequently seen at these ages. However, the stercoral perforation caused by fecaloma is a rare situation to occur. The rectosigmoid colon is the most affected colonic segment. It is seen in older patients with concomitant diseases and a low quality of life. PRESENTATION OF CASE: Here in this case, we have to report an 83 - year-old male patient who came to the emergency room with complaints of abdominal pain and constipation for two days...
September 14, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28933424/the-efficacy-and-safety-of-cilostazol-as-an-alternative-to-aspirin-in-chinese-patients-with-aspirin-intolerance-after-coronary-stent-implantation-a-combined-clinical-study-and-computational-system-pharmacology-analysis
#7
Ying Xue, Zhi-Wei Feng, Xiao-Ye Li, Zi-Heng Hu, Qing Xu, Zi Wang, Jia-Hui Cheng, Hong-Tao Shi, Qi-Bing Wang, Hong-Yi Wu, Xiang-Qun Xie, Qian-Zhou Lv
Dual antiplatelet therapy (DAT) with aspirin and clopidogrel is the standard regimen to achieve rapid platelet inhibition and prevent thrombotic events. Currently, little information is available regarding alternative antiplatelet therapy in patients with an allergy or intolerance to aspirin. Although cilostazol is already a common alternative to aspirin in clinical practice in China, its efficacy and safety remain to be determined. We retrospectively analyzed 613 Chinese patients who had undergone primary percutaneous coronary intervention (PCI)...
September 21, 2017: Acta Pharmacologica Sinica
https://www.readbyqxmd.com/read/28931790/clinical-characteristics-and-long-term-outcomes-of-rotational-atherectomy%C3%A3-j2t-multicenter-registry
#8
Iwao Okai, Tomotaka Dohi, Shinya Okazaki, Kentaro Jujo, Makoto Nakashima, Hisao Otsuki, Kazuki Tanaka, Hiroyuki Arashi, Ryuta Okabe, Fukuko Nagura, Yugo Nara, Hiroshi Tamura, Takeshi Kurata, Hideyuki Kawashima, Hiroyuki Kyono, Junichi Yamaguchi, Katsumi Miyauchi, Ken Kozuma, Nobuhisa Hagiwara, Hiroyuki Daida
BACKGROUND: Rotational atherectomy (RA) is an adjunct tool for the management of heavily calcified coronary lesions during percutaneous coronary intervention (PCI), but the long-term clinical outcomes of RA use remain unclear in this drug-eluting stent era.Methods and Results:This multi-center registry assessed the characteristics and outcomes of patients treated by RA for calcified coronary lesions between 2004 and 2015. Among 1,090 registered patients, mean age was 70±10 years and 815 (75%) were male...
September 21, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28929334/efficacy-of-biolimus-a9-eluting-stent-for-treatment-of-right-coronary-ostial-lesion-with-intravascular-ultrasound-guidance-a-multi-center-registry
#9
Kenya Nasu, Yuji Oikawa, Maoto Habara, Shinichi Shirai, Hidetoshi Abe, Makoto Kadotani, Ryo Gotoh, Hidenari Hozawa, Hiroshi Ota, Takashi Suzuki, Yoshihisa Shibata, Masaki Tanabe, Yuya Nakagawa, Takeshi Serikawa, Shiro Nagasaka, Yasuyo Takeuchi, Yoshihide Fujimoto, Hiroshi Tamura, Yuichi Kobori, Junji Yajima, Tadanori Aizawa, Takahiko Suzuki
The aim of this study was to assess the efficacy of a biolimus A9-eluting stent in patients with a right coronary artery (RCA) ostial lesion. Ostial lesions of the RCA have been a limitation of percutaneous coronary intervention even in the drug-eluting stent (DES) era. However, clinical outcomes after the deployment of a second generation DES to an RCA ostial lesion with intravascular ultrasound (IVUS) guidance have not been fully elucidated. From September 2011 to March 2013, 74 patients were enrolled in 17 centers from Japan...
September 19, 2017: Cardiovascular Intervention and Therapeutics
https://www.readbyqxmd.com/read/28924604/is-it-possible-to-perform-gastric-endoscopic-submucosal-dissection-without-discontinuation-of-a-single-antiplatelet-of-thienopyridine-derivatives
#10
Satoshi Ono, Masahiro Myojo, Hideaki Harada, Kunihiro Tsuji, Daisuke Murakami, Satoshi Suehiro, Hisashi Doyama, Jiro Ando, Itaru Saito, Mitsuhiro Fujishiro, Issei Komuro, Kazuhiko Koike
BACKGROUND AND STUDY AIMS : Combined use of thienopyridine derivatives and other antithrombotic agents is reported to be a risk factor for postoperative bleeding after gastric endoscopic submucosal dissection (ESD). However, risk associated with a single thienopyridine derivative has not been evaluated. In this study, we aimed to evaluate bleeding risks of gastric ESD without discontinuation of a single thienopyridine derivative agent. PATIENTS AND METHODS:  This multicenter, prospective, observational cohort study included patients who had undergone implantation of a coronary artery stent and who were taking a combination of aspirin antiplatelet therapy and a thienopyridine derivative agent...
September 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28923692/polymer-free-biolimus-a9-coated-stents-in-the-treatment-of-de-novo-coronary-lesions-with-short-dapt-9-month-angiographic-and-clinical-follow-up-of-the-prospective-multicenter-biofreedom-usa-clinical-trial
#11
Ron Waksman, Guy N Piegari, Ameer Kabour, Louis Cannon, John Wang, George Adams, Naresh Solankhi, Anthony Smeglin, Dean J Kereiakes, Roy Leiboff, Mia-Ashley Spad, Rebecca Torguson, Nina Chandra, Roshni Bastian, Jolanda DeGroot, Margaret W Kayo, Hans-Peter Stoll, Hector M Garcia-Garcia
BACKGROUND: BioFreedom is a polymer- and carrier-free drug-coated stent that delivers Biolimus A9 to the vessel wall. Our purpose was to evaluate the efficacy and safety of this DCS in patients with short-duration dual antiplatelet therapy. METHODS: The BioFreedom US IDE feasibility trial was a single-arm, open-label, prospective study of patients requiring stenting of de novo lesions. Patients received 3 months of DAPT, repeat angiography at 9 months, and clinical follow-up at multiple intervals...
July 31, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28923550/feelings-of-being-disabled-as-a-prognostic-factor-for-mortality-in-men-and-women-post-pci-up-to-12years
#12
Michael J Bergmann, Elisabeth M W J Utens, Tom A J de Jager, Sumant P Radhoe, Joost Daemen, Mattie J Lenzen, Ron T van Domburg, Karolijn Dulfer
BACKGROUND: It remains unclear whether feelings of being disabled are a relevant psychological factor that determines long term outcome after percutaneous coronary intervention (PCI). Therefore, we evaluated 'feelings of being disabled' as an independent risk factor for mortality 12years post-PCI. METHODS: The study population comprised a consecutive series of CAD patients (n=845) treated with PCI as part of the Taxus-Stent Evaluated At Rotterdam Cardiology Hospital (T-SEARCH) registry...
September 14, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28920634/outcomes-analysis-of-stent-graft-repair-for-thoracic-aorta-emergencies
#13
Mourad Boufi, Florent Vernet, Bianca Dona, Olivier Hartung, Anderson D Loundou, Martine Haccoun, Marc Leone, Yves S Alimi
BACKGROUND: This study aimed to identify patient, pathology and procedure-related factors affecting perioperative and mid-term mortality of thoracic aorta emergencies. METHODS: Between 2007 and 2014, patients treated emergently with thoracic stent-graft were retrospectively reviewed. Variables analyzed were: age, renal insufficiency, shock, cardiac arrest, transfer status, pathology, debranching procedures, operation duration, vascular access and European System for Cardiac Operative Risk Evaluation (EuroSCORE)...
December 2017: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28919628/coronary-artery-bypass-graft-with-endarterectomy-and-stent-removal-in-patient-with-multivessel-in-stent-restenosis
#14
S S Husain, C M Ahmed, A B Adhikary, S A Sunny, M N Hasan
In the age of stent deployment after balloon angioplasty. In stent restenosis (ISR) has become a major concern. Various coronary interventional measures and coronary artery bypass graft (CABG) has employed to manage the ISR. Although CABG seems to offer advantages over other coronary intervention methods in patients with multi vessel ISR; lack of appropriate graftable vessels often make the surgery difficult and end up with incomplete revascularization. Coronary endarterectomy with stent removal mitigated some of the limitations of CABG but initial results of this surgical measure were not favorable...
July 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28916600/white-blood-cell-count-and-major-adverse-cardiovascular-events-after-percutaneous-coronary-intervention-in-the-contemporary-era-insights-from-the-paris-study-patterns-of-non-adherence-to-anti-platelet-regimens-in-stented-patients-registry
#15
Binita Shah, Usman Baber, Stuart J Pocock, Mitchell W Krucoff, Cono Ariti, C Michael Gibson, Philippe Gabriel Steg, Giora Weisz, Bernhard Witzenbichler, Timothy D Henry, Annapoorna S Kini, Thomas Stuckey, David J Cohen, Ioannis Iakovou, George Dangas, Melissa B Aquino, Samantha Sartori, Alaide Chieffo, David J Moliterno, Antonio Colombo, Roxana Mehran
BACKGROUND: Elevated white blood cell (WBC) count is associated with increased major adverse cardiovascular events (MACE) in the setting of acute coronary syndrome. The aim of this study was to evaluate whether similar associations persist in an all-comers population of patients undergoing percutaneous coronary intervention in the contemporary era. METHODS AND RESULTS: In the multicenter, prospective, observational PARIS study (Patterns of Non-Adherence to Anti-Platelet Regimens in Stented Patients Registry), 4222 patients who underwent percutaneous coronary intervention in the United States and Europe between July 1, 2009, and December 2, 2010, were evaluated...
September 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28915509/device-motion-indication-a-novel-image-based-tool-to-measure-relative-device-motion-during-coronary-intervention
#16
Rami Abu Fanne, Simcha Ron Meisel, Avraham Shotan, Aharon Frimerman
BACKGROUND: Movement of the stent delivery system in the coronary bed as a result of the cardiac cycle is a well-known clinical observation that usually is either underestimated or ignored. This effect may potentially jeopardize precise stent deployment. We used a novel technology to objectively measure the relative intracoronary device motion in the different coronary segments throughout the cardiac cycle. METHODS: A total of 193 patients undergoing coronary angiography were enrolled and their studies were analyzed for device movement using the SyncVision System (Philips Volcano)...
September 15, 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/28903139/percutaneous-coronary-intervention-vs-coronary-artery-bypass-grafting-in-patients-with-left-main-coronary-artery-stenosis-a-systematic-review-and-meta-analysis
#17
Daniele Giacoppo, Roisin Colleran, Salvatore Cassese, Antonio H Frangieh, Jens Wiebe, Michael Joner, Heribert Schunkert, Adnan Kastrati, Robert A Byrne
Importance: In patients with left main coronary artery (LMCA) stenosis, coronary artery bypass grafting (CABG) has been the standard therapy for several decades. However, some studies suggest that percutaneous coronary intervention (PCI) with drug-eluting stents may be an acceptable alternative. Objective: To compare the long-term safety of PCI with drug-eluting stent vs CABG in patients with LMCA stenosis. Data Sources: PubMed, Scopus, EMBASE, Web of Knowledge, and ScienceDirect databases were searched from December 18, 2001, to February 1, 2017...
September 13, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28895771/platelet-reactivity-adjusted-antiplatelet-therapy-in-patients-with-percutaneous-coronary-intervention-a-meta-analysis-of-randomized-controlled-trials
#18
Zhenhua Xing, Liang Tang, Zhaowei Zhu, Jiabing Huang, Xiaofan Peng, Xinqun Hu
Numerous number of evidences show that high on-treatment platelet reactivity is a well-known risk factor for adverse events in patients after percutaneous coronary intervention (PCI). Controversial situations still exist regarding the effectiveness of tailoring antiplatelet therapy according to platelet function monitoring. The PubMed, Embase, and Cochrane Central databases were searched for randomized trials comparing platelet reactivity-adjusted antiplatelet therapy with conventional antiplatelet therapy in patients undergoing PCI...
September 12, 2017: Platelets
https://www.readbyqxmd.com/read/28895301/early-leaflet-thrombosis-complicating-transcatheter-implantation-of-a-sapien-3-valve-in-a-native-right-ventricular-outflow-tract
#19
Mounir Riahi, Philipp Blanke, John Webb, Ronald G Carere
A 59-year-old female with Tetralogy of Fallot had a previous complete repair with RVOT patch enlargement. She developed subsequent severe symptomatic (NYHA III) pulmonary regurgitation with severe RV dilatation. She had a concomitant interstitial lung disease secondary to hypersensitivity pneumonitis that precluded her from cardiac surgery. After preprocedural assessment using computed tomography, echocardiography and invasive angiography we decided to implant a 29 mm Edwards Sapien 3 valve without pre-stenting...
September 12, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28894594/effectiveness-and-safety-of-the-absorb-bioresorbable-vascular-scaffold-for-the-treatment-of-coronary-artery-disease-systematic-review-and-meta-analysis-of-randomized-clinical-trials
#20
Rita Pavasini, Matteo Serenelli, Francesco Gallo, Giulia Bugani, Salvatore Geraci, Paolo Vicinelli, Gianluca Campo
BACKGROUND: In the last years bioresorbable vascular scaffold (BVS) become a new therapeutic option for interventional cardiologists, with the advantage of a scaffold inducing a possible vessel wall restoration. Nevertheless, several trials tried to prove the safety and efficacy profile of scaffolds, but with conflicting results. METHODS: A systematic review and meta-analysis was performed. The search was carried out in PubMed, Google Scholar, Biomed Central and Cochrane Library between January and March 2017...
August 2017: Journal of Thoracic Disease
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