Wimonrat Panpetch, Pratsanee Hiengrach, Sumanee Nilgate, Somying Tumwasorn, Naraporn Somboonna, Alisa Wilantho, Piraya Chatthanathon, Piyapan Prueksapanich, Asada Leelahavanichkul
Candida albicans is abundant in the human gut mycobiota but this species does not colonize the mouse gastrointestinal tract. C. albicans administration in dextran-sulfate solution (DSS) induced-colitis mouse model (DSS+ Candida ) might resemble more to human condition, therefore, a DSS colitis model with Candida administration was studied; first, to test the influence of fungi in DSS model and second, to test the efficacy of Lactobacillus rhamnosus L34. We demonstrated serum (1→3)-β-D-glucan (BG) elevation in patients with IBD and endoscopic moderate colitis in clinical remission, supporting the possible influence of gut fungi toward IBD in human...
September 18, 2019: Gut Microbes