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https://www.readbyqxmd.com/read/29932381/endoscope-assisted-contralateral-transmaxillary-approach-to-the-clivus-and-the-hypoglossal-canal-technical-case-report
#1
Eva Pamias-Portalatin, Deependra Mahato, Jordina Rincon-Torroella, Tito Vivas-Buitrago, Alfredo Quiñones-Hinojosa, Kofi O Boahene
Clival lesions are still considered surgically complex due to their anatomical location. Critical structures, such as the internal carotid arteries (ICAs), cavernous sinuses, cranial nerves, and brainstem, may be encased within the lesion. Although advances in endoscopic endonasal approaches have provided new routes to these lesions, exposure and resection of clival tumors through the endonasal route remain a technical challenge. Here, the authors report a left-sided endoscopic transmaxillary approach to access the right aspect of the clivus and the hypoglossal canal...
June 22, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29932380/comparison-of-flow-diversion-with-clipping-and-coiling-for-the-treatment-of-paraclinoid-aneurysms-in-115-patients
#2
Michael A Silva, Alfred P See, Priyank Khandelwal, Ashutosh Mahapatra, Kai U Frerichs, Rose Du, Nirav J Patel, Mohammad A Aziz-Sultan
OBJECTIVE Paraclinoid aneurysms represent approximately 5% of intracranial aneurysms (Drake et al. [1968]). Visual impairment, which occurs in 16%-40% of patients, is among the most common presentations of these aneurysms (Day [1990], Lai and Morgan [2013], Sahlein et al. [2015], and Silva et al. [2017]). Flow-diverting stents, such as the Pipeline Embolization Device (PED), are increasingly used to treat these aneurysms, in part because of their theoretical reduction of mass effect (Fiorella et al. [2009])...
June 22, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29931268/placenta-to-the-rescue-limb-salvage-using-dehydrated-human-amnion-chorion-membrane
#3
Victoria Schlanser, Andrew Dennis, Katarina Ivkovic, Kimberly Joseph, Matthew Kaminsky, Thomas Messer, Stathis Poulakidas, Frederic Starr, Faran Bokhari
Reconstruction of skin and soft tissue wounds can pose a unique surgical challenge. This is especially true for cases of exposed bone and tendon where soft tissue loss is extensive and opportunities for tissue advancement or rotation are limited. A clinical case is presented describing an experience with dehydrated human amnion/chorion membrane (dHACM, EpiFix®/AmnioFix®, MiMedx Group, Marietta, GA) graft to obtain granulation over an open fracture with desiccated bone. The 22-year-old female trauma patient presented with high-grade bilateral lower extremity soft tissue loss after being run over and dragged by a semitruck...
December 5, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/29930875/multiple-meningiomas-in-two-male-to-female-transsexual-patients-with-hormone-replacement-therapy-a-report-of-two-cases-and-a-brief-literature-review
#4
Rahul Raj, Miikka Korja, Päivi Koroknay-Pál, Mika Niemelä
Background: Exogenous sex hormones may play a role in meningioma development and growth. Thus, transsexual patients being on long-standing hormone replacement therapy (HRT) may be at particular risk for meningioma development and growth. Here we present two cases of two male-to-female transsexual patients taking HRT for an extended period of time with both patients requiring surgical treatment at our institution due to multiple growing meningiomas. Case Description: The first patient was a 50-year-old genetic male (male-to-female transsexual) who presented 7 years after an extensive sex-change operation due to progressive bitemporal visual defects...
2018: Surgical Neurology International
https://www.readbyqxmd.com/read/29930460/anterior-megalophthalmos-is-visual-restoration-possible
#5
Alok Sati, Somasheila I Murthy, S Arjun, Varsha M Rathi
We report two cases of anterior megalophthalmos with cataract. Both cases have megalocornea, cavernous anterior chamber, enlarged iris-lens diaphragm, and normal axial length. The vision was less due to cataract. To restore vision, phacoemulsification was performed in each eye in both cases. Intraoperatively, to overcome anatomical challenges, we made scleral tunnel incision, stained anterior capsule, and fixated intraocular lens (IOL) by different techniques. In thefirst case, IOL was fixated through the sclera, whereas in the second case, IOL stabilization was achieved by capturing the optic in anterior capsulorhexis margin and placing the haptics in sulcus...
May 2018: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/29929034/craniotomy-for-a-large-and-aggressive-de-novo-cavernous-malformation-resection-in-the-basal-ganglia-region
#6
Zhiyong Yan, Shusheng Che, Yingbin Jiao, JianPeng Wang, Xingze Li, Chao Wang
Cerebral cavernous malformations (CCMs) are present in up to 0.5% of the general population. While CCMs have been considered congenital lesions, numerous reports have observed de novo formations in patients with the familial form of CCM and in patients after cranial radiotherapy. Outside of these circumstances, there is scant evidence as to the potential etiologies of CCM. We present a 48-year-old woman with a medical history of endometrial hyperplasia concomitant endometrial polyps demonstrating a large de novo CCM, which grew to a large size in a period of 20 months...
June 18, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29928263/prolactin-producing-pituitary-carcinoma-hypopituitarism-and-graves-disease-report-of-a-challenging-case-and-literature-review
#7
Rita Bettencourt-Silva, Josué Pereira, Sandra Belo, Daniela Magalhães, Joana Queirós, Davide Carvalho
Introduction: The diagnosis of pituitary carcinoma is very rare, requires the evidence of metastatic disease, and has a poor overall survival. Malignant prolactinoma frequently requires dopamine agonist therapy, pituitary surgery, radiotherapy, and even chemotherapy. Case description: A 19-year-old female presented with galactorrhea, primary amenorrhea, and left hemianopsia. Complementary study detected hyperprolactinemia and a pituitary macroadenoma with cavernous sinus invasion and suprasellar growth...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29927439/-the-informative-value-of-various-methods-for-identifying-acid-fast-bacilli-in-relation-to-the-degree-of-tuberculosis-process-activity
#8
V A Zinserling, M M Agapov, A N Orlov
Carbol fuchsin (Ziehl-Neelsen) staining is a major method used since the late nineteenth century to detect Mycobacterium tuberculosis in the tissues. At the same time, the number of mycobacteria does not frequently show a clinical and morphological correspondence to the activity of the infectious process. OBJECTIVE: To reveal the morphological characteristics of Mycobacterium tuberculosis in patients with long-lasting tuberculosis. MATERIAL AND METHODS: Twenty-four autopsies of verified fibrous-cavernous tuberculosis were examined...
2018: Arkhiv Patologii
https://www.readbyqxmd.com/read/29927438/-pituitary-lactotroph-adenomas-resistant-to-dopamine-agonist-treatment-histological-and-immunohistochemical-characteristics
#9
N S Fedorova, A Yu Abrosimov, L K Dzeranova, E A Pigarova, I I Dedov
OBJECTIVE: To present the histological and immunohistochemical characteristics of pituitary lactotroph adenomas (PLAs) resistant to dopamine agonist treatment. SUBJECT AND METHODS: The investigators examined paraffin-embedded blocks and histological sections obtained from 19 patients (13 women, 6 men), whose median age was 29 (19, 38) years, after surgical treatment (adenomectomy) for PLAs resistant to dopamine agonist treatment. Immunohistological examination was performed using antibodies against prolactin (PRL), growth hormone (GH), thyroid-stimulating hormone (TSH), adrenocorticotropic hormone (ACTH), luteinizing hormone (LH), follicle-stimulating hormone (FSH), type 2 dopamine receptors (DR2 ), estrogen receptors-α (ERα), the proliferation marker Ki-67, and the endothelial cell marker CD34...
2018: Arkhiv Patologii
https://www.readbyqxmd.com/read/29920768/systemic-corticosteroids-may-be-beneficial-for-managing-severe-or-refractory-orbital-cellulitis-in-children
#10
Anna Brameli, Liat Ashkenazi-Hoffnung, Dror Giloni, Ronit Friling, Gabriel Chodick, Daniel Landau, Oded Scheuerman
Orbital cellulitis infects the orbital tissues, with chemosis and periorbital swelling accompanied by limited eye movements, proptosis or decreased visual acuity (1). The most common cause is rhino-sinusitis extending into the orbit, especially when the ethmoidal sinuses are involved (1). Reported complications have included subperiosteal abscesses, orbital abscesses and cavernous sinus thrombophlebitis (1). This article is protected by copyright. All rights reserved.
June 19, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29920585/endoscopic-resection-of-hemorrhaged-third-ventricle-cavernous-malformation-2-dimensional-operative-video
#11
Giorgio Palandri, Thomas Sorenson, Mino Zucchelli, Nicola Acciarri, Paolo Mantovani, Carmelo Sturiale
Cavernous malformations of the third ventricle are uncommon vascular lesions. Evidence suggests that cavernous malformations in this location might have a more aggressive natural history due to their risk of intraventricular hemorrhage and hydrocephalus.1 The gold standard of treatment is considered to be microsurgical gross total resection of the lesion. However, with progressive improvement in endoscopic capabilities, several authors have recently advocated for the role of minimally-invasive neuroendoscopy for resecting intraventricular cavernous malformations...
June 16, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29920249/endothelial-colony-forming-cells-from-human-umbilical-cord-blood-improved-severe-erectile-dysfunction-in-obese-type-ii-diabetic-rats
#12
Abrar Al-Mahmood Siddiquee, P Ganesan Adaikan, Lang Chu Lau, Baharudin Bin Said, Mark Chong, Jerry Chan, Swee Hin Teoh
AIM: To investigate the effect of intracavernous injection of human umbilical cord blood derived endothelial colony forming cells (HUCB ECFCs) on erectile dysfunction (ED) in Zucker Diabetic Fatty (ZDF) rat model. METHODS: Erectile function was assessed by cavernous nerve electrostimulation in ZDF rats aged 20-28 weeks. Following confirmation of severe ED at the age of 28 weeks, 21 ZDF rats were randomly assigned to three experimental groups: 1 million ECFCs, 2 million ECFCs, and phosphate buffered saline (PBS)...
June 16, 2018: Life Sciences
https://www.readbyqxmd.com/read/29916092/multiple-hepatic-sclerosing-hemangiomas-a-case-report-and-review-of-the-literature
#13
Kyohei Yugawa, Tomoharu Yoshizumi, Noboru Harada, Takashi Motomura, Norifumi Harimoto, Shinji Itoh, Toru Ikegami, Yuji Soejima, Yoshihiko Maehara
BACKGROUND: Hepatic sclerosing hemangioma, a very rare benign tumor, is characterized by fibrosis and hyalinization occurring in association with degeneration of a hepatic cavernous hemangioma. Such atypical hemangiomas can be diagnosed incorrectly as primary or metastatic malignancies based on imaging characteristics. We present herein a rare case of giant and multiple hepatic sclerosing hemangiomas that are difficult to differentiate from hepatic malignancies and review the relevant literature...
June 19, 2018: Surgical Case Reports
https://www.readbyqxmd.com/read/29911023/cavernous-sinus-syndrome-in-dogs-and-cats-case-series-2002-2015
#14
Aslynn M Jones, Ellison Bentley, Helena Rylander
The cavernous sinus (CS) is a paired venous sinus that runs along either side of the pituitary gland on the floor of the calvarium. Cavernous sinus syndrome (CSS) refers to deficits in more than one of the cranial nerves III, IV, V, and VI, as they are in close association in this region. The purpose of this study was to identify the presenting complaints, neurologic findings, diagnosis, and outcomes in dogs and cats with confirmed cavernous sinus syndrome (CSS). Medical records between 2002 and 2015 were reviewed...
2018: Open Veterinary Journal
https://www.readbyqxmd.com/read/29906812/congenital-arteriovenous-malformation-of-the-scalp-involving-the-orbit
#15
Alberto Feletti, Stavros Dimitriadis, Stefano Vallone, Giacomo Pavesi
BACKGROUND:  Arteriovenous malformations (AVMs) of the scalp are rare and infrequently encountered by the neurosurgeon. CASE DESCRIPTION:  We report a unique case of a 42-year-old patient who presented with a progressive worsening of visual acuity in the right eye (lower quadrantanopia) and palpebral ptosis. Physical examination revealed a right exophthalmos and a right frontoparietal scalp soft swelling when the patient was in the supine position. Neurologic work-up showed a scalp AVM extending into the orbit and connected to an intraorbital cavernous angioma...
June 15, 2018: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/29906579/outcomes-of-aggressive-surgical-resection-in-growth-hormone-secreting-pituitary-adenomas-with-cavernous-sinus-invasion
#16
Hun Ho Park, Eui Hyun Kim, Cheol Ryong Ku, Eun Jig Lee, Sun Ho Kim
OBJECTIVE: Cavernous sinus (CS) invasion is an unfavorable factor hindering remission of growth hormone (GH)-secreting pituitary adenomas. However, few data exist on aggressive surgical resection. The authors investigate the role of CS exploration for GH-secreting pituitary adenomas with CS invasion. METHODS: We classified 132 patients with GH-secreting pituitary adenomas invading CS into 4 groups. The patients underwent surgery using a microsurgical transsphenoidal approach (TSA) with assistance of an endoscope...
June 12, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29905877/transsylvian-transinsular-approach-for-an-insular-cavernous-malformation-resection-3-dimensional-operative-video
#17
Justin Mascitelli, Sirin Gandhi, Ernest Wright, Michael T Lawton
Surgical resection of insular lesions is challenging due to their proximity to critical neurovascular structures such as the middle cerebral arteries (MCA), Sylvian veins, thalamus, internal capsule (IC), and lenticulostriate arteries. A surgical series using the transsylvian-transinsular approach to treat cerebrovascular pathologies reported ∼5% permanent neurological morbidity.1,2 This case demonstrates the utility of this approach for resecting an insular cavernous malformation (CM).A 25-yr-old female presented with an acute-onset right homonymous hemianopsia...
June 14, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29905585/conservative-treatment-for-penetrating-injuries-involving-the-cavernous-sinus-response
#18
Timothy J McCulley, Clarissa Kum, Jessica R Chang, Anna M Gruener
No abstract text is available yet for this article.
June 13, 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29905510/bleeding-risk-of-cerebral-cavernous-malformations-in-patients-on-%C3%AE-blocker-medication-a-cohort-study
#19
Johannes Goldberg, Christian Jaeggi, Daniel Schoeni, Pasquale Mordasini, Andreas Raabe, David Bervini
OBJECTIVE Cerebral cavernous malformations (CCMs) are frequently diagnosed vascular malformations of the brain. Although most CCMs are asymptomatic, some can be responsible for intracerebral hemorrhage or seizures. In selected cases, microsurgical resection is the preferred treatment option. Treatment with the unselective β-blocker propranolol has been presumed to stabilize and eventually lead to CCM size regression in a limited number of published case series; however, the underlying mechanism and evidence for this effect remain unclear...
June 15, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29904889/clinical-presentation-and-management-of-headache-in-pituitary-tumors
#20
REVIEW
Himanshu Suri, Carrie Dougherty
PURPOSE OF REVIEW: This article provides an overview of headache in the setting of pituitary adenoma. The purpose of this article is to educate providers on the association, possible pathophysiology, and the clinical presentation of headache in pituitary tumor. RECENT FINDINGS: Recent prospective evaluations indicate that risk factors for development of headache in the setting of pituitary adenoma include highly proliferative tumors, cavernous sinus invasion, and personal or family history of headache...
June 15, 2018: Current Pain and Headache Reports
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