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listeria meningitis

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https://www.readbyqxmd.com/read/28929964/-investigation-of-bacterial-and-viral-etiology-in-community-acquired-central-nervous-system-infections-with-molecular-methods
#1
Hasip Kahraman, Alper Tünger, Şebnem Şenol, Hörü Gazi, Meltem Avcı, Bahar Örmen, Nesrin Türker, Sabri Atalay, Şükran Köse, Sercan Ulusoy, Meltem Işıkgöz Taşbakan, Oğuz Reşat Sipahi, Tansu Yamazhan, Zeynep Gülay, Sema Alp Çavuş, Hüsnü Pullukçu
In this multicenter prospective cohort study, it was aimed to evaluate the bacterial and viral etiology in community-acquired central nervous system infections by standart bacteriological culture and multiplex polymerase chain reaction (PCR) methods. Patients hospitalized with central nervous system infections between April 2012 and February 2014 were enrolled in the study. Demographic and clinical information of the patients were collected prospectively. Cerebrospinal fluid (CSF) samples of the patients were examined by standart bacteriological culture methods, bacterial multiplex PCR (Seeplex meningitis-B ACE Detection (Streptococcus pneumoniae, Neisseria meningitidis, Haemophilus influenzae, Listeria monocytogenes, Group B streptococci) and viral multiplex PCR (Seeplex meningitis-V1 ACE Detection kits herpes simplex virus-1 (HSV1), herpes simplex virus-2 (HSV2), varicella zoster virus (VZV), cytomegalovirus (CMV), Epstein Barr virus (EBV) and human herpes virus 6 (HHV6)) (Seeplex meningitis-V2 ACE Detection kit (enteroviruses))...
July 2017: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28887627/-sepsis-masquerading-as-delirium
#2
REVIEW
A Seifert, C S Hartog, J Zweigner, W Schummer, K Reinhart
A previously healthy 60-year-old patient presented to the emergency department with severe headache, altered personality and fever. He was treated for bacterial meningitis with delirium of unknown cause but presumed to be due to alcohol withdrawal. Despite receiving the antibiotic therapy regimen recommended for bacterial meningitis the patient's condition rapidly deteriorated with profound delirium and tachypnea. The intensivist who was consulted immediately suspected sepsis-associated organ failure and admitted the patient to the intensive care unit (ICU)...
September 8, 2017: Der Anaesthesist
https://www.readbyqxmd.com/read/28883240/listeria-monocytogenes-septicemia-and-meningitis-caused-by-listeria-enteritis-complicating-ulcerative-colitis
#3
Takahiro Inoue, Toshinao Itani, Noriko Inomata, Kazuya Hara, Ikuhisa Takimoto, Shunya Iseki, Kensuke Hamada, Kanna Adachi, Shunsuke Okuyama, Yukari Shimada, Motohito Hayashi, Jun Mimura
An 80-year-old man, who had been diagnosed with ulcerative colitis, was admitted due to a fever and bloody diarrhea and was treated with a glucocorticoid and azathioprine. After 5 days, he developed an impaired consciousness, headache, and neck stiffness. A sample of the colonic mucosa, blood cultures, and cerebrospinal fluid revealed Listeria monocytogenes infection. Intravenous ampicillin improved the symptoms of fever, bloody diarrhea, and headache without any neurological sequelae. Physicians should consider that Listeria enteritis complicating ulcerative colitis can cause septicemia and meningitis in immunosuppressed patients...
September 6, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28671588/implications-of-neuroinvasive-bacterial-peptides-on-rodents-behaviour-and-neurotransmission
#4
Aneela Taj, Nusrat Jamil
Neuroinvasive microbes are capable of applying their influences on the autonomic nervous system (ANS) of the host followed by the involvement of central nervous system (CNS) by releasing extracellular metabolites that may cause alterations in the biochemical and neurophysiological environment. Consequently synaptic, neuroendocrine, peripheral immune, neuro-immune, and behavioural responses of the host facilitate the progression of infection. The present study was designed to extrapolate the effects of crude and purified extracellular peptides of neuropathogenic bacteria on behavioural responses and neurotransmission of Sprague Dawley (SD) models...
July 2, 2017: Pathogens
https://www.readbyqxmd.com/read/28662145/prevalence-and-antibiotic-resistance-profiles-of-cerebrospinal-fluid-pathogens-in-children-with-acute-bacterial-meningitis-in-yunnan-province-china-2012-2015
#5
Hongchao Jiang, Min Su, Liyue Kui, Hailin Huang, Lijuan Qiu, Li Li, Jing Ma, Tingyi Du, Mao Fan, Qiangming Sun, Xiaomei Liu
Acute bacterial meningitis is still considered one of the most dangerous infectious diseases in children. To investigate the prevalence and antibiotic resistance profiles of cerebrospinal fluid (CSF) pathogens in children with acute bacterial meningitis in Southwest China, CSF samples from 179 meningitis patients (3 days to 12 years old) with positive culture results were collected from 2012 to 2015. Isolated pathogens were identified using the Vitek-32 system. Gram stain results were used to guide subcultures and susceptibility testing...
2017: PloS One
https://www.readbyqxmd.com/read/28616745/bacterial-meningitis-complicating-the-course-of-liver-cirrhosis
#6
Pasquale Pagliano, Giovanni Boccia, Francesco De Caro, Silvano Esposito
Meningitis is rarely reported in studies investigating bacterial infections in patients affected by liver cirrhosis. We investigated the findings of bacterial meningitis in patients affected by liver cirrhosis referred to our department in a 16-year period. MATERIALS: Patients with cirrhosis and bacterial meningitis were enrolled. Cirrhosis was defined by liver histology or clinical, laboratory, and ultrasonographic and endoscopic findings. Bacterial meningitis was defined by cerebro-spinal fluid pleocytosis (>10/mcl) and characteristic clinical presentation...
June 14, 2017: Infection
https://www.readbyqxmd.com/read/28600447/the-epidemiology-management-and-outcomes-of-bacterial-meningitis-in-infants
#7
MULTICENTER STUDY
Lynda Ouchenir, Christian Renaud, Sarah Khan, Ari Bitnun, Andree-Anne Boisvert, Jane McDonald, Jennifer Bowes, Jason Brophy, Michelle Barton, Joseph Ting, Ashley Roberts, Michael Hawkes, Joan L Robinson
OBJECTIVES: The pathogens that cause bacterial meningitis in infants and their antimicrobial susceptibilities may have changed in this era of increasing antimicrobial resistance, use of conjugated vaccines, and maternal antibiotic prophylaxis for group B Streptococcus (GBS). The objective was to determine the optimal empirical antibiotics for bacterial meningitis in early infancy. METHODS: This was a cohort study of infants <90 days of age with bacterial meningitis at 7 pediatric tertiary care hospitals across Canada in 2013 and 2014...
July 2017: Pediatrics
https://www.readbyqxmd.com/read/28592578/bacterial-meningitis-in-finland-1995-2014-a-population-based-observational-study
#8
Aleksandra Polkowska, Maija Toropainen, Jukka Ollgren, Outi Lyytikäinen, J Pekka Nuorti
OBJECTIVES: Bacterial meningitis remains an important cause of morbidity and mortality worldwide. Its epidemiological characteristics, however, are changing due to new vaccines and secular trends. Conjugate vaccines against Haemophilus influenzae type b and Streptococcus pneumoniae (10-valent) were introduced in 1986 and 2010 in Finland. We assessed the disease burden and long-term trends of five common causes of bacterial meningitis in a population-based observational study. METHODS: A case was defined as isolation of S...
June 6, 2017: BMJ Open
https://www.readbyqxmd.com/read/28588016/commensal-microbes-provide-first-line-defense-against-listeria-monocytogenes-infection
#9
Simone Becattini, Eric R Littmann, Rebecca A Carter, Sohn G Kim, Sejal M Morjaria, Lilan Ling, Yangtsho Gyaltshen, Emily Fontana, Ying Taur, Ingrid M Leiner, Eric G Pamer
Listeria monocytogenes is a foodborne pathogen that causes septicemia, meningitis and chorioamnionitis and is associated with high mortality. Immunocompetent humans and animals, however, can tolerate high doses of L. monocytogenes without developing systemic disease. The intestinal microbiota provides colonization resistance against many orally acquired pathogens, and antibiotic-mediated depletion of the microbiota reduces host resistance to infection. Here we show that a diverse microbiota markedly reduces Listeria monocytogenes colonization of the gut lumen and prevents systemic dissemination...
July 3, 2017: Journal of Experimental Medicine
https://www.readbyqxmd.com/read/28540315/invasive-listeria-monocytogenes-gastroenteritis-leading-to-stupor-bacteremia-fever-and-diarrhea-a-rare-life-threatening-condition
#10
Hassan Mehmood, Asghar Dil Jan Khan Marwat, Noman Ahmed Jang Khan
Listeria monocytogenes is a gram-positive, rod-shaped organism that can cause serious infections such as meningitis, invasive gastroenteritis, and endocarditis. Every year 1600 people in the United States are affected, with significant mortality of 260 people annually. Listeria gastroenteritis has the third highest mortality rate among all the food-borne infection. Invasive listeriosis most commonly affect pregnant women, those in extremes of ages, people with comorbid diseases, and people with weakened immune response...
April 2017: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/28536811/listeriosis-during-pregnancy
#11
REVIEW
Mitko Madjunkov, Shahnaz Chaudhry, Shinya Ito
PURPOSE: Listeriosis is a rare foodborne illness caused by Listeria monocytogenes. It can be transmitted by consuming contaminated ready-to-eat food, long shelf-life products, deli meats, and soft cheeses. Listeria has a predilection to affect immunocompromised patients, elderly people, pregnant women and neonates. In particular, pregnant women are at ~18 times greater risk of infection than general population due to specific pregnancy-related suppressed cell-mediated immunity and placental tropism of L...
August 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28509139/unusual-listeria-monocytogenes-peritonitis-in-peritoneal-dialysis-patient-with-liver-cirrhosis-a-case-report-and-review-of-literature
#12
Miloš Mitrović, P Đurić, A Janković, V Todorov, J Tošić-Dragović, N Simović, T Damjanović, N Dimković
Spontaneous Listeria peritonitis is well described in liver failure, but is uncommon in peritoneal dialysis patients. Atypical cases where peritonitis symptoms develop after systemic manifestations are rare and challenging for diagnostic. A 57-year-old peritoneal dialysis patient with history of ethylic cirrhosis was admitted after epileptic seizure. On admission, patient was soporous without signs of peritonitis and meningitis. Patient's peritoneal effluent was clear, with normal leukocytes. Cranial CT scan showed no abnormalities...
May 2017: CEN Case Reports
https://www.readbyqxmd.com/read/28508419/case-control-study-shows-that-neonatal-pneumococcal-meningitis-cannot-be-distinguished-from-group-b-streptococcus-cases
#13
Alexandra Arfi, Robert Cohen, Emmanuelle Varon, Stéphane Béchet, Stéphane Bonacorsi, Corinne Levy
AIM: Streptococcus pneumoniae (S. pneumoniae) is sometimes implicated in neonatal bacterial meningitis. This study described the demographic, clinical and biological features of neonatal S. pneumoniae meningitis and compared pneumococcal and group B streptococcal (GBS) neonatal meningitis. METHODS: We conducted a case-control study that compared neonates, aged one to 28 days with S. pneumoniae meningitis or GBS meningitis. Each case with S. pneumoniae was randomly matched to four control patients with GBS by age group and study year...
May 16, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28489800/characteristics-and-outcome-of-spontaneous-bacterial-meningitis-in-patients-with-cancer-compared-to-patients-without-cancer
#14
Virginia Pomar, Natividad Benito, Joaquin López-Contreras, Pere Coll, Mercedes Gurguí, Pere Domingo
In cancer patients, who are frequently immunocompromised, bacterial meningitis (BM) can be a severe complication, with a different presentation, etiology, and course, compared to patients without cancer. Our objective is to compare the characteristics and outcomes of BM in patients with and without cancer. A single-center, prospective observational cohort study, conducted between 1982 and 2012, in a tertiary university hospital in Barcelona (Spain). The main outcome measure is in-hospital mortality. We evaluated 659 episodes of BM; 97 (15%) had active cancer...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28484584/etiology-and-laboratory-abnormalities-in-bacterial-meningitis-in-neonates-and-young-infants
#15
David Kotzbauer, Curtis Travers, Craig Shapiro, Margaux Charbonnet, Anthony Cooley, Deborah Andresen, Gary Frank
We conducted a retrospective review of electronic medical records of all cases of bacterial meningitis in neonates and young infants at our institution from 2004 to 2014. Fifty-six cases were identified. The most common causative organism was group B streptococcus, followed by Escherichia coli and then Listeria monocytogenes. Forty-four of the 56 patients in the study had abnormalities of the blood white blood cell (WBC) count. The most common WBC count abnormalities were leukopenia and elevation of the immature to total (I:T) neutrophil ratio...
April 6, 2017: Clinics and Practice
https://www.readbyqxmd.com/read/28473173/listeria-monocytogenes-meningitis-pcr-multiplex-diagnosis
#16
Ana Infante-Urrios, Fernando Buñuel-Adan, Gregoria Gázquez-Gómez, Victoria Ortiz de la Tabla-Ducasse
No abstract text is available yet for this article.
May 1, 2017: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/28461391/host-serine-threonine-kinases-mtor-and-protein-kinase-c-%C3%AE-promote-inlb-mediated-entry-of-listeria-monocytogenes
#17
Manmeet Bhalla, Daria Law, Georgina C Dowd, Keith Ireton
The bacterial pathogen Listeria monocytogenes causes foodborne illnesses resulting in gastroenteritis, meningitis, or abortion. Listeria induces its internalization into some human cells through interaction of the bacterial surface protein InlB with the host receptor tyrosine kinase Met. InlB-dependent entry requires localized polymerization of the host actin cytoskeleton. The signal transduction pathways that act downstream of Met to regulate actin filament assembly or other processes during Listeria uptake remain incompletely characterized...
July 2017: Infection and Immunity
https://www.readbyqxmd.com/read/28419853/listeria-monocytogenes-meningitis-in-the-netherlands-1985-2014-a-nationwide-surveillance-study
#18
Merel M Koopmans, Merijn W Bijlsma, Matthijs C Brouwer, Diederik van de Beek, Arie van der Ende
OBJECTIVES: Listeria monocytogenes can cause sepsis and meningitis. We report national surveillance data on L. monocytogenes meningitis in the Netherlands, describing incidence changes, genetic epidemiology and fatality rate. METHODS: We analyzed data from the Netherlands Reference Laboratory of Bacterial Meningitis for cases of L. monocytogenes meningitis. Strains were assessed by serotyping and bacterial population structure by multi-locus sequence typing. RESULTS: A total of 375 cases of Listeria meningitis were identified between 1985 and 2014...
July 2017: Journal of Infection
https://www.readbyqxmd.com/read/28392538/listeria-monocytogenes-meningitis-complicating-rotavirus-gastroenteritis-in-an-immunocompetent-child
#19
Takuma Ohnishi, Akiko Kawano, Mayumi Araki, Yuko Hamahata, Machiko Usui, Motoko Shimoyamada, Takuya Tamame, Masayuki Akashi, Seiji Sato
Listeria monocytogenes only occasionally causes bacterial meningitis in immunocompetent children. We report a case of L. monocytogenes meningitis associated with rotavirus gastroenteritis. The patient was a previously healthy 20-month-old girl who was admitted because of sustained fever and lethargy after suffering from gastroenteritis for 6 days. The patient's peripheral white blood cell count was 18,600/µL and the C-reactive protein level was 2.44 mg/dL. A stool sample tested positive for rotavirus antigen...
April 7, 2017: Keio Journal of Medicine
https://www.readbyqxmd.com/read/28376817/listeria-monocytogenes-infection-associated-with-alemtuzumab-a-case-for-better-preventive-strategies
#20
Trygve Holmøy, Hedda von der Lippe, Truls Michael Leegaard
BACKGROUND: The mortality of septicaemia, meningitis and encephalitis caused by Listeria monocytogenes is 20-40%. Twenty-one cases of invasive listeriosis associated with alemtuzumab, including at least 16 in patients with multiple sclerosis, have been published or reported to the World Health Organization Case Safety Reports Database. Three cases were fatal, including at least one patient treated for multiple sclerosis in 2016. CASE PRESENTATION: We report a patient with multiple sclerosis who developed pyrexia, nausea and abdominal discomfort few hours after the third and last infusion of her second alemtuzumab cycle...
April 4, 2017: BMC Neurology
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