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https://www.readbyqxmd.com/read/27881637/closing-the-brief-case-neonatal-meningitis-caused-by-listeria-monocytogenes-diagnosed-by-multiplex-molecular-panel
#1
EDITORIAL
Vikram Anand, Jenna Holmen, Michael Neely, Pia S Pannaraj, Jennifer Dien Bard
No abstract text is available yet for this article.
December 2016: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/27881634/the-brief-case-neonatal-meningitis-caused-by-listeria-monocytogenes-diagnosed-by-multiplex-molecular-panel
#2
EDITORIAL
Vikram Anand, Jenna Holmen, Michael Neely, Pia S Pannaraj, Jennifer Dien Bard
No abstract text is available yet for this article.
December 2016: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/27723768/diversity-of-listeria-monocytogenes-strains-of-clinical-and-food-chain-origins-in-belgium-between-1985-and-2014
#3
S Bertrand, P J Ceyssens, M Yde, K Dierick, F Boyen, J Vanderpas, R Vanhoof, W Mattheus
Listeriosis is a rare but severe disease, mainly caused by Listeria monocytogenes. This study shows the results of the laboratory-based surveillance of Listeriosis in Belgium over the period 1985-2014. Besides the incidence and some demographic data we present also more detailed microbiological and molecular characteristics of human strains isolated since 2000. The strains from the latter period were compared to food and animal strains from the same period. Our study shows that different food matrices were commonly contaminated with L...
2016: PloS One
https://www.readbyqxmd.com/read/27249907/listeriosis-is-it-a-rare-disease-in-thailand
#4
Weerasak Lawtongkum, Usa Thisyakorn
The prevalence of Listeria monocytogenes infection has been characterized as rare in Thailand. Within one month, 3 cases of listeriosis were seen at Vachira Phuket Hospital in Phuket, Thailand. Two cases were neonates with septicemia, of which one made an uneventful recovery and the other expired. The third case was an eleven-year-old boy with meningitis who also succumbed to his illness. All isolated L. monocytogenes were sensitive to ampicillin. An outbreak investigation revealed no L. monocytogenes contamination in tested food sources in Phuket...
February 2016: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
https://www.readbyqxmd.com/read/27074026/il-12p40-il-10-producing-precd8%C3%AE-clec9a-dendritic-cells-are-induced-in-neonates-upon-listeria-monocytogenes-infection
#5
David Torres, Arnaud Köhler, Sandrine Delbauve, Irina Caminschi, Mireille H Lahoud, Ken Shortman, Véronique Flamand
Infection by Listeria monocytogenes (Lm) causes serious sepsis and meningitis leading to mortality in neonates. This work explored the ability of CD11c(high) lineage DCs to induce CD8+ T-cell immune protection against Lm in mice before 7 days of life, a period symbolized by the absence of murine IL-12p70-producing CD11c(high)CD8α+ dendritic cells (DCs). We characterized a dominant functional Batf3-dependent precursor of CD11c(high) DCs that is Clec9A+CD205+CD24+ but CD8α- at 3 days of life. After Lm-OVA infection, these pre-DCs that cross-present Ag display the unique ability to produce high levels of IL-12p40 (not IL-12p70 nor IL-23), which enhances OVA-specific CD8+ T cell response, and regulatory IL-10 that limits OVA-specific CD8+ T cell response...
April 2016: PLoS Pathogens
https://www.readbyqxmd.com/read/26829754/uncovering-listeria-monocytogenes-hypervirulence-by-harnessing-its-biodiversity
#6
Mylène M Maury, Yu-Huan Tsai, Caroline Charlier, Marie Touchon, Viviane Chenal-Francisque, Alexandre Leclercq, Alexis Criscuolo, Charlotte Gaultier, Sophie Roussel, Anne Brisabois, Olivier Disson, Eduardo P C Rocha, Sylvain Brisse, Marc Lecuit
Microbial pathogenesis studies are typically performed with reference strains, thereby overlooking within-species heterogeneity in microbial virulence. Here we integrated human epidemiological and clinical data with bacterial population genomics to harness the biodiversity of the model foodborne pathogen Listeria monocytogenes and decipher the basis of its neural and placental tropisms. Taking advantage of the clonal structure of this bacterial species, we identify clones epidemiologically associated either with food or with human central nervous system (CNS) or maternal-neonatal (MN) listeriosis...
March 2016: Nature Genetics
https://www.readbyqxmd.com/read/26772166/reductions-in-neonatal-listeriosis-collateral-benefit-of-group-b-streptococcal-prophylaxis
#7
Brian Lee, Jason G Newland, Ravi Jhaveri
OBJECTIVES: We tested the hypothesis that declines in Listeria monocytogenes in infants are related to declines in rates of early-onset Group B Streptococcus (GBS) infections associated with widespread prophylaxis using agents with Listeria activity. METHODS: We performed a retrospective cohort analysis using a national administrative database Pediatric Health Information System (PHIS). We searched for ICD-9 codes for Listeriosis in infants <30 days old and for early-onset GBS infection of any kind in infants <5 days old during the study period...
March 2016: Journal of Infection
https://www.readbyqxmd.com/read/26674793/-a-clinical-analysis-of-16-patients-with-maternal-listeriosis
#8
Peng Wang, Yingqian Chen, Huanling Wang, Shuang Yang, Yingchun Xu, Taisheng Li
OBJECTIVE: To summarize the clinical characteristics and outcome of maternal listeriosis so as to improve the understanding of disease and the level of diagnosis and treatment. METHODS: Retrospectively, 16 cases of maternal listeriosis, who were treated at Peking Union Medical College Hospital between March 2007 and December 2014 were reviewed. Maternal listeriosis is defined when a pregnant woman presents with symptoms as listeriosis, meanwhile Listeria monocytogenes is isolated from sterile tissue or peripheral blood, or from a non-sterile site (uterus swab) or pathological evidence of chorioamnionitis...
September 2015: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/26409737/characterization-of-epidemic-clones-of-listeria-monocytogenes-serotype-4b-isolated-from-humans-and-meat-products-in-brazil
#9
André Victor Barbosa, Aloysio De Mello Figueiredo Cerqueira, Leonardo Alves Rusak, Cristhiane Moura Falavina Dos Reis, Nilma Cintra Leal, Ernesto Hofer, Deyse Christina Vallim
INTRODUCTION: Listeria monocytogenes is an important foodborne pathogen and the 4b serotype is responsible for many cases of human listeriosis reported in Brazil. Several listeriosis outbreaks worldwide have involved a small number of well-defined clonal groups, designated as epidemic clones (ECs). METHODOLOGY: We studied 71 strains of serotype 4b, including 25 isolates from human cases of listeriosis and 46 from meat-based foods, collected in Brazil between 1977 and 2010...
September 2015: Journal of Infection in Developing Countries
https://www.readbyqxmd.com/read/26376314/nosocomial-neonatal-listeria-monocytogenes-transmission-by-stethoscope
#10
LETTER
Lucy Fullerton, Gabrielle Norrish, Catherine J Wedderburn, Stephanie Paget, Robin Basu Roy, Clare Cane
No abstract text is available yet for this article.
September 2015: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/26292299/blood-volume-required-for-detection-of-low-levels-and-ultralow-levels-of-organisms-responsible-for-neonatal-bacteremia-by-use-of-bactec-peds-plus-f-plus-aerobic-f-medium-and-the-bd-bactec-fx-system-an-in-vitro-study
#11
Diana P Lancaster, David F Friedman, Kathleen Chiotos, Kaede V Sullivan
We used an in vitro technique to investigate blood volumes required to detect bacteremia and fungemia with low concentrations of an organism. At 1 to 10 CFU/ml, Escherichia coli, Staphylococcus epidermidis, Staphylococcus aureus, Listeria monocytogenes, Candida albicans, and Candida parapsilosis isolates were detected in volumes as low as 0.5 ml. Detection of Streptococcus agalactiae and detection of bacteremia at <1 CFU/ml were unreliable.
November 2015: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/26231373/pregnancy-associated-human-listeriosis-virulence-and-genotypic-analysis-of-listeria-monocytogenes-from-clinical-samples
#12
Dharmendra Kumar Soni, Durg Vijai Singh, Suresh Kumar Dubey
Listeria monocytogenes, a life-threatening pathogen, poses severe risk during pregnancy, may cause abortion, fetal death or neonatal morbidity in terms of septicemia and meningitis. The present study aimed at characterizing L. monocytogenes isolated from pregnant women based on serotyping, antibiotic susceptibility, virulence genes, in vivo pathogenicity test and ERIC- and REP-PCR fingerprint analyses. The results revealed that out of 3700 human clinical samples, a total of 30 (0.81%) isolates [12 (0.80%) from placental bit (1500), 18 (0...
September 2015: Journal of Microbiology / the Microbiological Society of Korea
https://www.readbyqxmd.com/read/26147648/age-related-gene-expression-differences-in-monocytes-from-human-neonates-young-adults-and-older-adults
#13
Michelle M Lissner, Brandon J Thomas, Kathleen Wee, Ann-Jay Tong, Tobias R Kollmann, Stephen T Smale
A variety of age-related differences in the innate and adaptive immune systems have been proposed to contribute to the increased susceptibility to infection of human neonates and older adults. The emergence of RNA sequencing (RNA-seq) provides an opportunity to obtain an unbiased, comprehensive, and quantitative view of gene expression differences in defined cell types from different age groups. An examination of ex vivo human monocyte responses to lipopolysaccharide stimulation or Listeria monocytogenes infection by RNA-seq revealed extensive similarities between neonates, young adults, and older adults, with an unexpectedly small number of genes exhibiting statistically significant age-dependent differences...
2015: PloS One
https://www.readbyqxmd.com/read/25938757/a-novel-mutation-leading-to-a-premature-stop-codon-in-inla-of-listeria-monocytogenes-isolated-from-neonatal-listeriosis
#14
Tereza Gelbíčová, Ivana Koláčková, Roman Pantůček, Renáta Karpíšková
The study objective was to investigate whether the strain of L. monocytogenes serotype 1/2c isolated from neonatal listeriosis carries a premature stop codon (PMSC) mutation in the inlA gene. The strain was characterized by serotyping, macrorestriction analysis after digestion with the restriction enzyme AscI, and sequencing of the inlA gene. The tested strain of serotype 1/2c and pulsotype 1 possesses a new type of point mutation leading to a PMSC in the inlA gene and production of truncated internalin A. The case of early onset form of neonatal listeriosis caused by serotype 1/2c with a PMSC mutation in the inlA gene confirmed the transplacental transmission potential of this strain...
April 2015: New Microbiologica
https://www.readbyqxmd.com/read/25784782/estimating-the-attack-rate-of-pregnancy-associated-listeriosis-during-a-large-outbreak
#15
Maho Imanishi, Janell A Routh, Marigny Klaber, Weidong Gu, Michelle S Vanselow, Kelly A Jackson, Loretta Sullivan-Chang, Gretchen Heinrichs, Neena Jain, Bernadette Albanese, William M Callaghan, Barbara E Mahon, Benjamin J Silk
BACKGROUND: In 2011, a multistate outbreak of listeriosis linked to contaminated cantaloupes raised concerns that many pregnant women might have been exposed to Listeria monocytogenes. Listeriosis during pregnancy can cause fetal death, premature delivery, and neonatal sepsis and meningitis. Little information is available to guide healthcare providers who care for asymptomatic pregnant women with suspected L. monocytogenes exposure. METHODS: We tracked pregnancy-associated listeriosis cases using reportable diseases surveillance and enhanced surveillance for fetal death using vital records and inpatient fetal deaths data in Colorado...
2015: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/25628458/empirical-antibiotic-cover-for-listeria-monocytogenes-infection-beyond-the-neonatal-period-a-time-for-change
#16
Ifeanyichukwu O Okike, Adedoyin Awofisayo, Bob Adak, Paul T Heath
No abstract text is available yet for this article.
May 2015: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/25476765/metal-ion-homeostasis-in-listeria-monocytogenes-and-importance-in-host-pathogen-interactions
#17
REVIEW
Helen E Jesse, Ian S Roberts, Jennifer S Cavet
Listeria monocytogenes is responsible for one of the most life-threatening food-borne infections and the leading cause of food-poisoning associated deaths in the UK. Infection may be of the unborn/newly born infant where disease may manifest as listeric abortion, stillbirth or late-onset neonatal listeriosis, while in adults, infection usually affects the central nervous system causing meningitis. Crucial to the survival of L. monocytogenes, both inside and outside the host, is its ability to acquire metals which act as cofactors for a broad range of its cellular proteins...
2014: Advances in Microbial Physiology
https://www.readbyqxmd.com/read/25361468/genetic-and-phenotypic-characterization-of-listeria-monocytogenes-from-human-clinical-cases-that-occurred-in-portugal-between-2008-and-2012
#18
Rui Magalhães, Vânia Ferreira, Isabel Santos, Gonçalo Almeida, Paula Teixeira
Listeria monocytogenes infection (listeriosis) is an uncommon but severe foodborne illness that affects mainly individuals with recognized underlying conditions: the elderly, immunocompromised individuals, and pregnant women and their fetuses. The aim of this study was to obtain epidemiological data on cases of listeriosis occurring in Portugal from 2008 through 2012, collected in hospitals on a voluntary basis. L. monocytogenes isolates were characterized by genoserotyping by multiplex polymerase chain reaction, DNA macrorestriction pulsed-field gel electrophoresis (PFGE), and determination of minimal inhibitory concentration (MIC, μg/mL) for 12 antibiotics...
November 2014: Foodborne Pathogens and Disease
https://www.readbyqxmd.com/read/25356132/listeria-infection-in-chinese-pregnant-women-and-neonates-from-shandong
#19
Jun Lv, Zhenli Qin, Yanhua Xu, Qiurong Xie
OBJECTIVE: This study aims to investigate the characters of pregnant women and neonates with listeria monocytogenes infections (L. monocytogenes) in Shandong of China. METHOD: Pregnant women with premature delivery or prenatal fever were recruited in 2013. Bacterial culture was performed for the umbilical cord blood and placental swab after delivery. The strains isolated were then analyzed for the virulence factors and classified based on the serotype and MLST typing...
2014: International Journal of Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/25098360/management-of-pregnant-women-with-presumptive-exposure-to-listeria-monocytogenes
#20
(no author information available yet)
: Listeriosis is predominantly a foodborne illness, with sporadic and outbreak-related cases tied to consumption of food contaminated with listeria (Listeria monocytogenes). The incidence of listeriosis associated with pregnancy is approximately 13 times higher than in the general population. Maternal infection may present as a nonspecific, flu-like illness with fever, myalgia, backache, and headache, often preceded by diarrhea or other gastrointestinal symptoms. However, fetal and neonatal infections can be severe, leading to fetal loss, preterm labor, neonatal sepsis, meningitis, and death...
August 5, 2014: Obstetrics and Gynecology
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