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https://www.readbyqxmd.com/read/28139432/clinical-features-and-prognostic-factors-of-listeriosis-the-monalisa-national-prospective-cohort-study
#1
Caroline Charlier, Élodie Perrodeau, Alexandre Leclercq, Benoît Cazenave, Benoît Pilmis, Benoît Henry, Amanda Lopes, Mylène M Maury, Alexandra Moura, François Goffinet, Hélène Bracq Dieye, Pierre Thouvenot, Marie-Noëlle Ungeheuer, Mathieu Tourdjman, Véronique Goulet, Henriette de Valk, Olivier Lortholary, Philippe Ravaud, Marc Lecuit
BACKGROUND: Listeriosis is a severe foodborne infection and a notifiable disease in France. We did a nationwide prospective study to characterise its clinical features and prognostic factors. METHODS: MONALISA was a national prospective observational cohort study. We enrolled eligible cases declared to the National Reference Center for Listeria (all microbiologically proven) between Nov 3, 2009, and July 31, 2013, in the context of mandatory reporting. The outcomes were analysis of clinical features, characterisation of Listeria isolates, and determination of predictors of 3-month mortality or persisting impairment using logistic regression...
January 28, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28045978/cord-blood-acute-phase-reactants-predict-early-onset-neonatal-sepsis-in-preterm-infants
#2
Leena B Mithal, Hannah L Palac, Ram Yogev, Linda M Ernst, Karen K Mestan
BACKGROUND: Early onset sepsis (EOS) is a major cause of morbidity and mortality in preterm infants, yet diagnosis remains inadequate resulting in missed cases or prolonged empiric antibiotics with adverse consequences. Evaluation of acute phase reactant (APR) biomarkers in umbilical cord blood at birth may improve EOS detection in preterm infants with intrauterine infection. METHODS: In this nested case-control study, infants (29.7 weeks gestation, IQR: 27.7-32...
2017: PloS One
https://www.readbyqxmd.com/read/27976567/successful-treatment-of-refractory-listeria-meningitis-and-bacteremia-with-trimethoprim-sulfamethoxazole-in-an-immunocompetent-child
#3
Meltem Polat, Soner Sertan Kara, Anıl Tapısız, Okşan Derinöz, Kayhan Çağlar, Hasan Tezer
Listeria monocytogenes is an important cause of life-threatening bacteremia and meningoencephalitis in neonates, pregnant women, the elderly, and immunocompromised individuals. However, it is an uncommon cause of illness in immunocompetent children beyond the neonatal period. Ampicillin with or without an aminoglycoside remains the best treatment for listeriosis. Here, we report a rare case of Listeria meningitis and bacteremia in a 7-month-old immunocompetent girl, which was refractory to ampicillin plus gentamicin treatment and successfully treated by the addition of TMP/SMX...
2016: Turkish Journal of Pediatrics
https://www.readbyqxmd.com/read/27930711/licheniocin-50-2-and-bacteriocins-from-lactococcus-lactis-subsp-lactis-biovar-diacetylactis-bgbu1-4-inhibit-biofilms-of-coagulase-negative-staphylococci-and-listeria-monocytogenes-clinical-isolates
#4
Ivana Cirkovic, Dragana D Bozic, Veselin Draganic, Jelena Lozo, Tanja Beric, Milan Kojic, Biljana Arsic, Eliana Garalejic, Slobodanka Djukic, Slavisa Stankovic
BACKGROUND: Coagulase negative staphylococci (CoNS) and Listeria monocytogenes have important roles in pathogenesis of various genital tract infections and fatal foetomaternal infections, respectively. The aim of our study was to investigate the inhibitory effects of two novel bacteriocins on biofilms of CoNS and L. monocytogenes genital isolates. METHODS: The effects of licheniocin 50.2 from Bacillus licheniformis VPS50.2 and crude extract of bacteriocins produced by Lactococcus lactis subsp...
2016: PloS One
https://www.readbyqxmd.com/read/27881637/closing-the-brief-case-neonatal-meningitis-caused-by-listeria-monocytogenes-diagnosed-by-multiplex-molecular-panel
#5
EDITORIAL
Vikram Anand, Jenna Holmen, Michael Neely, Pia S Pannaraj, Jennifer Dien Bard
No abstract text is available yet for this article.
December 2016: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/27881634/the-brief-case-neonatal-meningitis-caused-by-listeria-monocytogenes-diagnosed-by-multiplex-molecular-panel
#6
EDITORIAL
Vikram Anand, Jenna Holmen, Michael Neely, Pia S Pannaraj, Jennifer Dien Bard
No abstract text is available yet for this article.
December 2016: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/27723768/diversity-of-listeria-monocytogenes-strains-of-clinical-and-food-chain-origins-in-belgium-between-1985-and-2014
#7
S Bertrand, P J Ceyssens, M Yde, K Dierick, F Boyen, J Vanderpas, R Vanhoof, W Mattheus
Listeriosis is a rare but severe disease, mainly caused by Listeria monocytogenes. This study shows the results of the laboratory-based surveillance of Listeriosis in Belgium over the period 1985-2014. Besides the incidence and some demographic data we present also more detailed microbiological and molecular characteristics of human strains isolated since 2000. The strains from the latter period were compared to food and animal strains from the same period. Our study shows that different food matrices were commonly contaminated with L...
2016: PloS One
https://www.readbyqxmd.com/read/27249907/listeriosis-is-it-a-rare-disease-in-thailand
#8
Weerasak Lawtongkum, Usa Thisyakorn
The prevalence of Listeria monocytogenes infection has been characterized as rare in Thailand. Within one month, 3 cases of listeriosis were seen at Vachira Phuket Hospital in Phuket, Thailand. Two cases were neonates with septicemia, of which one made an uneventful recovery and the other expired. The third case was an eleven-year-old boy with meningitis who also succumbed to his illness. All isolated L. monocytogenes were sensitive to ampicillin. An outbreak investigation revealed no L. monocytogenes contamination in tested food sources in Phuket...
February 2016: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
https://www.readbyqxmd.com/read/27074026/il-12p40-il-10-producing-precd8%C3%AE-clec9a-dendritic-cells-are-induced-in-neonates-upon-listeria-monocytogenes-infection
#9
David Torres, Arnaud Köhler, Sandrine Delbauve, Irina Caminschi, Mireille H Lahoud, Ken Shortman, Véronique Flamand
Infection by Listeria monocytogenes (Lm) causes serious sepsis and meningitis leading to mortality in neonates. This work explored the ability of CD11c(high) lineage DCs to induce CD8+ T-cell immune protection against Lm in mice before 7 days of life, a period symbolized by the absence of murine IL-12p70-producing CD11c(high)CD8α+ dendritic cells (DCs). We characterized a dominant functional Batf3-dependent precursor of CD11c(high) DCs that is Clec9A+CD205+CD24+ but CD8α- at 3 days of life. After Lm-OVA infection, these pre-DCs that cross-present Ag display the unique ability to produce high levels of IL-12p40 (not IL-12p70 nor IL-23), which enhances OVA-specific CD8+ T cell response, and regulatory IL-10 that limits OVA-specific CD8+ T cell response...
April 2016: PLoS Pathogens
https://www.readbyqxmd.com/read/26829754/uncovering-listeria-monocytogenes-hypervirulence-by-harnessing-its-biodiversity
#10
Mylène M Maury, Yu-Huan Tsai, Caroline Charlier, Marie Touchon, Viviane Chenal-Francisque, Alexandre Leclercq, Alexis Criscuolo, Charlotte Gaultier, Sophie Roussel, Anne Brisabois, Olivier Disson, Eduardo P C Rocha, Sylvain Brisse, Marc Lecuit
Microbial pathogenesis studies are typically performed with reference strains, thereby overlooking within-species heterogeneity in microbial virulence. Here we integrated human epidemiological and clinical data with bacterial population genomics to harness the biodiversity of the model foodborne pathogen Listeria monocytogenes and decipher the basis of its neural and placental tropisms. Taking advantage of the clonal structure of this bacterial species, we identify clones epidemiologically associated either with food or with human central nervous system (CNS) or maternal-neonatal (MN) listeriosis...
March 2016: Nature Genetics
https://www.readbyqxmd.com/read/26772166/reductions-in-neonatal-listeriosis-collateral-benefit-of-group-b-streptococcal-prophylaxis
#11
Brian Lee, Jason G Newland, Ravi Jhaveri
OBJECTIVES: We tested the hypothesis that declines in Listeria monocytogenes in infants are related to declines in rates of early-onset Group B Streptococcus (GBS) infections associated with widespread prophylaxis using agents with Listeria activity. METHODS: We performed a retrospective cohort analysis using a national administrative database Pediatric Health Information System (PHIS). We searched for ICD-9 codes for Listeriosis in infants <30 days old and for early-onset GBS infection of any kind in infants <5 days old during the study period...
March 2016: Journal of Infection
https://www.readbyqxmd.com/read/26674793/-a-clinical-analysis-of-16-patients-with-maternal-listeriosis
#12
Peng Wang, Yingqian Chen, Huanling Wang, Shuang Yang, Yingchun Xu, Taisheng Li
OBJECTIVE: To summarize the clinical characteristics and outcome of maternal listeriosis so as to improve the understanding of disease and the level of diagnosis and treatment. METHODS: Retrospectively, 16 cases of maternal listeriosis, who were treated at Peking Union Medical College Hospital between March 2007 and December 2014 were reviewed. Maternal listeriosis is defined when a pregnant woman presents with symptoms as listeriosis, meanwhile Listeria monocytogenes is isolated from sterile tissue or peripheral blood, or from a non-sterile site (uterus swab) or pathological evidence of chorioamnionitis...
September 2015: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/26409737/characterization-of-epidemic-clones-of-listeria-monocytogenes-serotype-4b-isolated-from-humans-and-meat-products-in-brazil
#13
André Victor Barbosa, Aloysio De Mello Figueiredo Cerqueira, Leonardo Alves Rusak, Cristhiane Moura Falavina Dos Reis, Nilma Cintra Leal, Ernesto Hofer, Deyse Christina Vallim
INTRODUCTION: Listeria monocytogenes is an important foodborne pathogen and the 4b serotype is responsible for many cases of human listeriosis reported in Brazil. Several listeriosis outbreaks worldwide have involved a small number of well-defined clonal groups, designated as epidemic clones (ECs). METHODOLOGY: We studied 71 strains of serotype 4b, including 25 isolates from human cases of listeriosis and 46 from meat-based foods, collected in Brazil between 1977 and 2010...
September 2015: Journal of Infection in Developing Countries
https://www.readbyqxmd.com/read/26376314/nosocomial-neonatal-listeria-monocytogenes-transmission-by-stethoscope
#14
LETTER
Lucy Fullerton, Gabrielle Norrish, Catherine J Wedderburn, Stephanie Paget, Robin Basu Roy, Clare Cane
No abstract text is available yet for this article.
September 2015: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/26292299/blood-volume-required-for-detection-of-low-levels-and-ultralow-levels-of-organisms-responsible-for-neonatal-bacteremia-by-use-of-bactec-peds-plus-f-plus-aerobic-f-medium-and-the-bd-bactec-fx-system-an-in-vitro-study
#15
Diana P Lancaster, David F Friedman, Kathleen Chiotos, Kaede V Sullivan
We used an in vitro technique to investigate blood volumes required to detect bacteremia and fungemia with low concentrations of an organism. At 1 to 10 CFU/ml, Escherichia coli, Staphylococcus epidermidis, Staphylococcus aureus, Listeria monocytogenes, Candida albicans, and Candida parapsilosis isolates were detected in volumes as low as 0.5 ml. Detection of Streptococcus agalactiae and detection of bacteremia at <1 CFU/ml were unreliable.
November 2015: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/26231373/pregnancy-associated-human-listeriosis-virulence-and-genotypic-analysis-of-listeria-monocytogenes-from-clinical-samples
#16
Dharmendra Kumar Soni, Durg Vijai Singh, Suresh Kumar Dubey
Listeria monocytogenes, a life-threatening pathogen, poses severe risk during pregnancy, may cause abortion, fetal death or neonatal morbidity in terms of septicemia and meningitis. The present study aimed at characterizing L. monocytogenes isolated from pregnant women based on serotyping, antibiotic susceptibility, virulence genes, in vivo pathogenicity test and ERIC- and REP-PCR fingerprint analyses. The results revealed that out of 3700 human clinical samples, a total of 30 (0.81%) isolates [12 (0.80%) from placental bit (1500), 18 (0...
September 2015: Journal of Microbiology / the Microbiological Society of Korea
https://www.readbyqxmd.com/read/26147648/age-related-gene-expression-differences-in-monocytes-from-human-neonates-young-adults-and-older-adults
#17
Michelle M Lissner, Brandon J Thomas, Kathleen Wee, Ann-Jay Tong, Tobias R Kollmann, Stephen T Smale
A variety of age-related differences in the innate and adaptive immune systems have been proposed to contribute to the increased susceptibility to infection of human neonates and older adults. The emergence of RNA sequencing (RNA-seq) provides an opportunity to obtain an unbiased, comprehensive, and quantitative view of gene expression differences in defined cell types from different age groups. An examination of ex vivo human monocyte responses to lipopolysaccharide stimulation or Listeria monocytogenes infection by RNA-seq revealed extensive similarities between neonates, young adults, and older adults, with an unexpectedly small number of genes exhibiting statistically significant age-dependent differences...
2015: PloS One
https://www.readbyqxmd.com/read/25938757/a-novel-mutation-leading-to-a-premature-stop-codon-in-inla-of-listeria-monocytogenes-isolated-from-neonatal-listeriosis
#18
Tereza Gelbíčová, Ivana Koláčková, Roman Pantůček, Renáta Karpíšková
The study objective was to investigate whether the strain of L. monocytogenes serotype 1/2c isolated from neonatal listeriosis carries a premature stop codon (PMSC) mutation in the inlA gene. The strain was characterized by serotyping, macrorestriction analysis after digestion with the restriction enzyme AscI, and sequencing of the inlA gene. The tested strain of serotype 1/2c and pulsotype 1 possesses a new type of point mutation leading to a PMSC in the inlA gene and production of truncated internalin A. The case of early onset form of neonatal listeriosis caused by serotype 1/2c with a PMSC mutation in the inlA gene confirmed the transplacental transmission potential of this strain...
April 2015: New Microbiologica
https://www.readbyqxmd.com/read/25784782/estimating-the-attack-rate-of-pregnancy-associated-listeriosis-during-a-large-outbreak
#19
Maho Imanishi, Janell A Routh, Marigny Klaber, Weidong Gu, Michelle S Vanselow, Kelly A Jackson, Loretta Sullivan-Chang, Gretchen Heinrichs, Neena Jain, Bernadette Albanese, William M Callaghan, Barbara E Mahon, Benjamin J Silk
BACKGROUND: In 2011, a multistate outbreak of listeriosis linked to contaminated cantaloupes raised concerns that many pregnant women might have been exposed to Listeria monocytogenes. Listeriosis during pregnancy can cause fetal death, premature delivery, and neonatal sepsis and meningitis. Little information is available to guide healthcare providers who care for asymptomatic pregnant women with suspected L. monocytogenes exposure. METHODS: We tracked pregnancy-associated listeriosis cases using reportable diseases surveillance and enhanced surveillance for fetal death using vital records and inpatient fetal deaths data in Colorado...
2015: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/25628458/empirical-antibiotic-cover-for-listeria-monocytogenes-infection-beyond-the-neonatal-period-a-time-for-change
#20
Ifeanyichukwu O Okike, Adedoyin Awofisayo, Bob Adak, Paul T Heath
No abstract text is available yet for this article.
May 2015: Archives of Disease in Childhood
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