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crystal methamphetamine

Ori Ben-Yehuda, Neil Siecke
No abstract text is available yet for this article.
March 2018: JACC. Heart Failure
Cuimei Liu, Wei Jia, Yu Han, Zhendong Hua
Some methamphetamine (MA) crystals contain pharmaceutical impurities resulting from the co-ingredients of medicines used for extracting ephedrine/pseudoephedrine. These pharmaceutical impurities and their related byproducts can reflect the trends in precursor chemicals and manufacturing sources. In this research, one pharmaceutical impurity related byproduct was detected in several seized MA samples synthesized by I/P (Nagai, Moscow, or Hypo) method. Its structure was postulated through the analysis of fragment ions in EI mass spectrum...
March 1, 2018: Drug Testing and Analysis
Liangbao Yang, Borong Yu, Pan Li, Binbin Zhou, Xianghu Tang, Shaofei Li
A sodium chloride crystals-driven spontaneously hot spots structure was demonstrated as SERS-active platform to get reproducible SERS signals and eliminate the need for mapping large areas in comparison with solution phase. During the process of solvent evaporation, the crystals produced in colloids induced silver aggregates assemble around themselves. And the micro-scale crystals can act as the template to obtain optical position, such that the assembled hot area is conventionally located during SERS measurements...
February 26, 2018: Chemistry: a European Journal
Mostafa Shokoohi, Mohammad Karamouzian, Hamid Sharifi, Afarin Rahimi-Movaghar, Adam W Carrico, Samira Hosseini Hooshyar, Ali Mirzazadeh
BACKGROUND: Worldwide, crystal methamphetamine (CM) use and associated high-risk sexual behaviors are a concern, but they are less studied among female sex workers (FSW) in developing countries. This study aimed to characterize the prevalence and individual, interpersonal, and structural correlates of self-reported past-month CM use among FSW in Iran. METHODS: FSW aged ≥ 18 years who reported penetrative sex with more than one client in the last year were recruited (analytic sample: 1295)...
February 14, 2018: Drug and Alcohol Dependence
Susanne Drückler, Martijn S van Rooijen, Henry J C de Vries
OBJECTIVES: Chemsex (i.e., drug use during sex) is practiced by some men who have sex with men (MSM) and is associated with high-risk behavior. In a cross-sectional study at the sexually transmitted infection (STI) clinic of Amsterdam, we explored chemsex practices, risk behavior, and STI prevalence. METHOD: A survey on chemsex (γ-hydroxybutyrate, crystal methamphetamine, and/or mephedrone) was offered to clinic clients during routine STI screening and to Amsterdam users of a gay online dating app...
November 15, 2017: Sexually Transmitted Diseases
Sean P Colyer, Nathan J Lachowsky, Zishan Cui, Julia Zhu, Heather L Armstrong, Matthew Taylor, Joshua Edward, Gbolahan Olarewaju, Robert S Hogg, Eric A Roth, David M Moore
BACKGROUND: Treatment as Prevention (TasP) leading to increased HIV treatment optimism among men who have sex with men (MSM) has been previously associated with behavioural risk compensation, though not yet via crystal methamphetamine (CM) use. Among HIV-negative MSM in a TasP environment, this study aimed to investigate the prevalence of recent CM use over time, examine the association between HIV treatment optimism and CM use and initiation, and identify correlates of recent CM use and predictors of CM initiation...
February 7, 2018: Drug and Alcohol Dependence
William Damon, Ryan McNeil, M-J Milloy, Ekaterina Nosova, Thomas Kerr, Kanna Hayashi
Reports of increasing methamphetamine use among vulnerable populations may be attributed in part to the adaptive use of stimulants in response to the loss of stable housing through residential eviction. We employed multivariable recurrent event extended Cox regression to examine the independent association between recent evictions and initiation of or relapse into crystal methamphetamine use among people who inject drugs in Vancouver, Canada enrolled in two prospective cohort studies. In a multivariable analysis, eviction remained independently associated with methamphetamine initiation or relapse (adjusted hazard ratio = 1...
February 7, 2018: Journal of Public Health
Ingrid Bakker, Leon Knoops
In response to the apparent rise in chemsex in the Netherlands Mainline Foundation interviewed 27 MSM about their crystal meth use and/or experience with injecting in a sexual context. These men were interviewed about their motivation for methamphetamine use, their sexual risk-taking behaviour, methods and context of their drug use, and their information- and care needs. In 2015 this resulted in the status report Tina and Slamming: MSM, Crystal Meth Use and Intravenous Drug Use in a Sexual Context. Following the publication of this report Mainline foundation has been offering harm-reduction intervention for MSM and promoting the development of a continuum of care by building networks, training professionals and investing in advocacy...
February 6, 2018: Sexual Health
Lisa Proebstl, Felicia Kamp, Gabi Koller, Michael Soyka
Methamphetamine use has spread in many European countries and the United States. The current review provides a summary and critical analysis of research on cognitive deficits associated with methamphetamine, also known as "crystal meth." The literature search performed for this review led us to the hypothesis that methamphetamine use is associated with persistent changes in brain metabolism that result in various impairments, such as deficits in memory, attention, and concentration. The dopaminergic system in particular seems to be affected...
January 15, 2018: Pharmacopsychiatry
Reece Cossar, Mark Stoové, Stuart A Kinner, Paul Dietze, Campbell Aitken, Michael Curtis, Amy Kirwan, James R P Ogloff
BACKGROUND: Dual substance dependence and psychiatric and psychological morbidities are overrepresented in prison populations and associated with reoffending. In the context of an increasing prison population in Australia, investigating the needs of vulnerable people in prison with a dual diagnosis can help inform in-prison screening and treatment and improve prison and community service integration and continuation of care. In this study we quantified psychiatric well-being in a sample of people in prison with a history of injecting drug use in Victoria, Australia, and identified factors associated with this outcome...
January 13, 2018: Health & Justice
Wei Xu, Yanyan Fu, Huan Liu, Qingguo He, Huimin Cao, Jiangong Cheng
In this contribution, completely different from traditional probes based on molecular host-guest interaction, crystal level interaction was proposed as an ultrasensitive design strategy for molecule detection. In such strategy, crystal-guest interaction triggered rapid crystal disaggregation to gain great signal change, far more efficient than molecule scale coupling. Highly ordered pyrene methanol (PM) crystal was self-assembled with hydrogen bond chain and π-π stacking force. Its {011} surface can be destabilized by methamphetamine hydrochlorate (MA, heavily used illicit drug) selectively and efficiently...
December 14, 2017: Analytical Chemistry
Hiroki Segawa, Kento Kumisaka, Ritsuko Sugita, Yuko T Iwata, Tadashi Yamamuro, Kenji Kuwayama, Kenji Tsujikawa, Tatsuyuki Kanamori, Hiroyuki Inoue
Methods to quickly purify methamphetamine hydrochloride from the cutting agent dimethyl sulfone for subsequent identification of confiscated crystalline samples using infrared absorption spectroscopy were compared and evaluated. Although sequential solvation and reprecipitation methods were simple, spectral contamination from dimethyl sulfone was inevitable and might affect the interpretation of the spectra. In addition, methamphetamine hydrochloride and dimethyl sulfone could form a solid solution because of solvation of both crystals into a single solution layer...
January 2018: Forensic Science International
Mark Aidan McKelvie, Yuksel Gercek
Methamphetamine hydrochloride, colloquially referred to as "crystal meth," is a potent psychoactive amphetamine derivate. Methamphetamine produces stimulant effects in the user including increased energy and alertness as well as inducing intense euphoric symptoms and suppressing appetite through its dopaminergic, serotonergic, and adrenergic actions. Use of methamphetamine can adversely affect cardiovascular, neurological, and gastrointestinal physiology leading to significant morbidity. We present a rare case of paralytic ileus secondary to methamphetamine abuse which has only once before been described in the literature...
2017: Case Reports in Surgery
Sterling McPherson, Michael Orr, Crystal Lederhos, Michael McDonell, Emily Leickly, Katherine Hirchak, Oladunni A Oluwoye, Sean M Murphy, Matthew Layton, John M Roll
Despite high rates of smoking (70-90%) and the severely negative impact of smoking on physical and mental health, only 12% of individuals receiving stimulant-use disorder treatment also receive smoking-cessation treatment. The aim of this investigation was to examine the effect of a contingency management (CM) intervention targeting methamphetamine (MA) use on cigarette smoking. Sixty-one adults with MA-use disorders who were smokers were assigned to CM or standard psychosocial treatment. Rates of smoking-negative breath samples (carbon monoxide <3 ppm) were compared between the two groups while controlling for baseline carbon monoxide level, marijuana use, MA use, and time...
October 13, 2017: Behavioural Pharmacology
Kim Usher, Debra Jackson, Cindy Woods, Jan Sayers, Rachel Kornhaber, Michelle Cleary
The crystalline form of methamphetamine, commonly known as crystal meth (crystal methamphetamine) or ICE, is a highly-addictive and powerful stimulant. Users of crystal meth often require emergency care, and are associated with a substantial burden of care by emergency care providers. The aim of the present qualitative study was to explore health professionals' experiences of providing care for patients affected by ICE who presented to the emergency department (ED). Nine semistructured interviews were conducted...
October 2017: International Journal of Mental Health Nursing
Elena Argento, Steffanie A Strathdee, Kenneth Tupper, Melissa Braschel, Evan Wood, Kate Shannon
OBJECTIVE: This study aimed to longitudinally investigate whether ever having used a psychedelic drug can have a protective effect on incidence of suicidality among marginalised women. DESIGN: Longitudinal community-based cohort study. SETTING: Data were drawn from a prospective, community-based cohort of marginalised women in Metro Vancouver, Canada. PARTICIPANTS: 766 women completed the baseline questionnaire between January 2010 and August 2014...
September 21, 2017: BMJ Open
Joseph J Palamar
Ecstasy (MDMA) has regained popularity in powder and crystalline form, known as Molly. However, it is unknown whether all Molly users are aware that Molly is ecstasy. A total of 1045 nightclub/festival-attending adults in New York City were surveyed about ecstasy/MDMA/Molly use in 2016. Users were asked if they agreed that "Molly is (or is supposed to be) ecstasy/MDMA." Of the 43.5% reporting lifetime use, 84.6% agreed that Molly is ecstasy, 9.5% disagreed, and 5.9% reported not knowing that Molly is ecstasy...
September 22, 2017: Journal of Psychoactive Drugs
Sulay Patel, Crystal R Leibrand, Preetha Palasuberniam, Pierre-Olivier Couraud, Babette Weksler, Fay M Jahr, Joseph L McClay, Kurt F Hauser, MaryPeace McRae
Human immunodeficiency (HIV) infection results in neurocognitive deficits in about one half of infected individuals. Despite systemic effectiveness, restricted antiretroviral penetration across the blood-brain barrier (BBB) is a major limitation in fighting central nervous system (CNS)-localized infection. Drug abuse exacerbates HIV-induced cognitive and pathological CNS changes. This study's purpose was to investigate the effects of the HIV-1 protein Tat and methamphetamine on factors affecting drug penetration across an in vitro BBB model...
December 2017: Antimicrobial Agents and Chemotherapy
Scott E Hadland, Evan Wood, Ekaterina Nosova, Thomas Kerr, Kora DeBeck
PURPOSE: Injection drug use is prevalent among street-involved youth, but patterns of cessation are poorly described. We identified drug use patterns preceding injection cessation among street-involved youth. METHODS: From September 2005 to May 2015, we collected data from the At-Risk Youth Study, a prospective cohort of street-involved youth in Vancouver, Canada, and limited the sample to actively injecting youth. The primary outcome was cessation of injecting self-reported at semiannual follow-up visits...
November 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
Helia Shariati, Heather L Armstrong, Zishan Cui, Nathan J Lachowsky, Julia Zhu, Praney Anand, Eric A Roth, Robert S Hogg, Greg Oudman, Christina Tonella, David M Moore
BACKGROUND: Cigarette smoking is common among gay, bisexual, and other men who have sex with men (GBMSM) and most of the mortality gap between HIV-positive and HIV-negative individuals is attributable to smoking. METHODS: We recruited sexually active HIV-positive and HIV-negative GBMSM age ≥16 years using respondent-driven sampling. Study visits occurred every six months for up to four years and included a computer-assisted self-interview and clinical assessment...
October 1, 2017: Drug and Alcohol Dependence
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