Antonio Cascajosa-Lira, Remedios Guzmán-Guillén, Silvia Pichardo, Alberto Baños, Jose M de la Torre, Nahum Ayala-Soldado, M Rosario Moyano-Salvago, Isabel Ortiz-Jaraba, Ana M Cameán, Angeles Jos
Propyl-propane thiosulfonate (PTSO), an antioxidant organosulfur compound present in the genus Allium , has become a potential natural additive for food and feed, as well as a possible biopesticide for pest control in plants. A toxicological assessment is necessary to verify its safety for livestock, consumers, and the environment. As part of the risk assessment of PTSO, this study was designed to explore its potential reproductive toxicity in mice following the OECD 416 guideline. The investigation spans two generations to comprehensively evaluate potential reproductive, teratogenic, and hereditary effects...
March 15, 2024: Antioxidants (Basel, Switzerland)