keyword
MENU ▼
Read by QxMD icon Read
search

Testosterone

keyword
https://www.readbyqxmd.com/read/29031192/growth-and-endocrine-function-in-children-with-dravet-syndrome
#1
Krista Eschbach, Sharon Scarbro, Elizabeth Juarez-Colunga, Victoria Allen, Stephanie Hsu, Kelly Knupp
PURPOSE: Dravet syndrome is an intractable childhood epilepsy syndrome most often associated with an SCN1A mutation. In our clinical practice, several patients with Dravet syndrome were noted to have short stature and endocrine dysfunction. This has not been reported in the literature. Our study aim was to describe growth measurements and endocrine abnormalities in children with Dravet syndrome. METHOD: A retrospective chart review was performed at a single institution...
September 29, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29030154/simultaneous-profiles-of-sulfonated-androgens-sulfonated-estrogens-and-sulfonated-progestogens-in-postpubertal-boars-sus-scrofa-domestica-measured-by-lc-ms-ms
#2
G Schuler, A Sánchez-Guijo, M F Hartmann, S A Wudy
Sulfonated steroids (s-St) have been usually regarded as inactive metabolites but are progressively considered as precursors for the intra-tissue formation of bioactive steroids. Moreover, independent effects without preceding removal of the sulfate group have been observed. We use the porcine testicular-epididymal compartment as a model to investigate the still largely unknown s-St physiology as the boar exhibits an intriguingly broad s-St spectrum predominantly originating from the testis. The application of LC-MS/MS in steroidomics enables the determination of unconjugated and intact sulfonated steroids with currently highest specificity and good sensitivity, allowing the concurrent measuring of numerous analytes in larger quantities of samples...
October 10, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29029336/differential-effects-of-exposure-to-single-versus-a-mixture-of-endocrine-disrupting-chemicals-on-steroidogenesis-pathway-in-mouse-testes
#3
Julio Buñay, Eduardo Larriba, Daniel Patiño-Garcia, Leonor Cruz-Fernandes, Sergio Castañeda-Zegarra, María Rodriguez-Fernandez, Jesús Del Mazo, Ricardo D Moreno
Endocrine-disrupting chemicals (EDCs) generate reproductive dysfunctions affecting the biosynthesis of steroid hormones and genes of the steroidogenic pathway. EDCs effects are mainly reported as a result of exposure to single compounds. However, humans are environmentally exposed to a mixture of EDCs. Herein, we assess chronic exposure to single alkylphenols and phthalates versus a mixture in mouse testes histology and steroidogenesis. Pregnant mice were exposed through drinking water to: 0.3 mg/Kg-body weight (BW)/day of each phthalate (DEHP, DBP, BBP), 0...
September 22, 2017: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/29029242/germ-cell-neoplasia-in-situ-and-preserved-fertility-despite-suppressed-gonadotropins-in-a-patient-with-testotoxicosis
#4
Li Juel Mortensen, Martin Blomberg Jensen, Peter Christiansen, Ann-Margrethe Rønholt, Anne Jørgensen, Hanne Frederiksen, John E Nielsen, Anand C Loya, Birgitte Grønkær Toft, Niels E Skakkebæk, Ewa Rajpert-De Meyts, Anders Juul
Context: Testotoxicosis is an autosomal dominant, male-limited disorder. Activating mutations in the Luteinizing Hormone Receptor gene (LHCGR) cause high autonomous testosterone secretion resulting in early-onset peripheral precocious puberty. Little is known about long-term consequences of testotoxicosis. Case Description: We present a rare case of a patient followed for 25 years with two remarkable outcomes; preserved fertility and germ cell neoplasia in situ (GCNIS)...
October 5, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29028670/cord-blood-bisphenol-a-levels-and-reproductive-and-thyroid-hormone-levels-of-neonates-the-hokkaido-study-on-environment-and-children-s-health
#5
Machiko Minatoya, Seiko Sasaki, Atsuko Araki, Chihiro Miyashita, Sachiko Itoh, Jun Yamamoto, Toru Matsumura, Takahiko Mitsui, Kimihiko Moriya, Kazutoshi Cho, Keita Morioka, Hisanori Minakami, Nobuo Shinohara, Reiko Kishi
BACKGROUND: Bisphenol A (BPA) is widely used and BPA exposure is nearly ubiquitous in developed countries. While animal studies have indicated adverse health effects of prenatal BPA exposure including reproductive dysfunction and thyroid function disruption possibly in a sex-specific manner, findings from epidemiologic studies have not been enough to prove these adverse effects. Given very limited research on human, the aim of this study was to investigate associations between cord blood BPA levels and reproductive and thyroid hormone levels of neonates and whether associations differed by neonate sex...
October 2017: Epidemiology
https://www.readbyqxmd.com/read/29028483/circulating-levels-of-sgp130-and-sex-hormones-in-male-patients-with-coronary-atherosclerotic-disease
#6
Yan Cui, Wen Dai, Yan Li
BACKGROUND AND AIMS: Inflammation and endocrine disorders are considered as major pathogenic factors of coronary atherosclerotic disease (CAD). Sgp130, a natural antagonist of IL-6 trans-signaling, and sex hormones, especially testosterone and estradiol, are prominently considered as anti-atherosclerotic. The aim of this study was to investigate the possible association between serum sgp130 and testosterone and estradiol in male CAD patients. METHODS: A total of 254 male patients with CAD and 122 male controls were recruited for this study...
September 4, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29026762/correlation-of-vitamin-d-with-metabolic-parameters-in-polycystic-ovarian-syndrome
#7
Arun Kumar, Satish Barki, Vinod Raghav, Ashutosh Chaturvedi, K V S Hari Kumar
BACKGROUND: Polycystic ovarian syndrome (PCOS) and hypovitaminosis D are the two most common endocrine disorders in young women leading to many adverse metabolic consequences. We evaluated the correlation of 25-hydroxy Vitamin D (25OHD) with metabolic parameters and insulin resistance in PCOS. MATERIALS AND METHODS: We included 100 PCOS patients (age 18-40 years, duration >6 months) serially, in this cross-sectional study. We excluded patients with past use of insulin sensitizers and hormone therapy...
January 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29026487/seasonal-variations-and-correlations-between-vitamin-d-and-total-testosterone-levels
#8
Moo-Yeol Sim, Soo-Hyun Kim, Kwang-Min Kim
BACKGROUND: Some studies have provided evidence for a possible association between vitamin D and testosterone levels; however, the evidence from studies in Koreans is inconsistent. In addition, insufficient evidence is available to support an association between seasonal variations in vitamin D and testosterone levels in Koreans. Therefore, we aimed to investigate the association between vitamin D and testosterone levels, and between seasonal variations in these levels in Korean men. METHODS: This cross-sectional study included 1,559 men, aged 25-86 years, who underwent a medical examination...
September 2017: Korean Journal of Family Medicine
https://www.readbyqxmd.com/read/29025782/olfactory-bulb-agenesis-with-normal-sexual-hormones
#9
Prayuth Tunsuriyawong, Krit Pongpirul, Tagann Chaisam, Petpring Prajuabpansri
An 18-year-old Caucasian man presented with a lack of sense of surrounding smell. The problem was first noticed when a family member discussed the smell of the food, which he had no idea what it was. The patient had normal development and sexual function, no history of trauma, surgery, chemical exposure or infection. Physical examination revealed no significant abnormalities. Smell threshold test using phenyl-ethyl-alcohol revealed bilateral anosmia. MRI showed bilateral aplastic olfactory bulbs and tracts associated with absent cortical growth of the olfactory sulci and asymmetrical gyrus rectus...
October 11, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29025356/associations-between-sleep-deprivation-and-salivary-testosterone-levels-in-male-university-students-a-prospective-cohort-study
#10
Mahmoud Suleiman Abu-Samak, Beisan Ali Mohammad, May Ibrahim Abu-Taha, Luai Zidan Hasoun, Shady Helmi Awwad
Sleep deprivation is a common health problem that is growing rapidly worldwide and it is associated with short- and long-term impacts on health. The aim of this study was to detect potential predictors of salivary testosterone (sT) association with sleep deprivation in Arab male university students. In this prospective cohort study, 77 university male students in the age range of 18 to 26 years were divided into two groups, sleep-deprived (SD) participants and non-sleep-deprived (NSD) participants. Sleep deprivation was defined as sleeping less than 5 hr per night...
October 1, 2017: American Journal of Men's Health
https://www.readbyqxmd.com/read/29025355/a-content-analysis-of-testosterone-websites-sex-muscle-and-male-age-related-thematic-differences
#11
Nicholas Ivanov, Jimmy Vuong, Peter B Gray
Male testosterone supplementation is a large and growing industry. How is testosterone marketed to male consumers online? The present exploratory study entailed a content coding analysis of the home pages of 49 websites focused on testosterone supplementation for men in the United States. Four hypotheses concerning anticipated age-related differences in content coding were also tested: more frequent longevity content toward older men, and more frequent social dominance/physical formidability, muscle, and sex content toward younger men...
October 1, 2017: American Journal of Men's Health
https://www.readbyqxmd.com/read/29024781/the-role-of-androgen-receptors-in-atherosclerosis
#12
REVIEW
Kaloyan Takov, Junxi Wu, Martin A Denvir, Lee B Smith, Patrick W F Hadoke
Male disadvantage in cardiovascular health is well recognised. However, the influence of androgens on atherosclerosis, one of the major causes of many life-threatening cardiovascular events, is not well understood. With the dramatic increase in clinical prescription of testosterone in the past decade, concerns about the cardiovascular side-effects of androgen supplementation or androgen deprivation therapy are increasing. Potential atheroprotective effects of testosterone could be secondary to (aromatase-mediated) conversion into oestradiol or, alternatively, to direct activation of androgen receptors (AR)...
October 9, 2017: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/29024156/relationships-between-the-second-to-fourth-digit-ratio-2d-4d-and-game-related-statistics-in-semi-professional-female-basketball-players
#13
Makailah Dyer, Sandra E Short, Martin Short, John T Manning, Grant R Tomkinson
OBJECTIVE: Digit ratio (2D:4D) is a negative correlate of sports performance, although this relationship may be weak in open-skill sports such as basketball. The primary aim was to quantify relationships between 2D:4D and game-related statistics in semi-professional female basketball players. The secondary aim was to quantify the differences in mean 2D:4Ds between players based on their position in the starting lineup. METHODS: Using a cross-sectional design, 64 female basketball players who competed in the South Australian Premier League were measured in-season for height, mass, and 2D:4D, with game-related statistics collected end-season...
October 12, 2017: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/29023546/steroid-hormones-and-psychological-responses-to-soccer-matches-insights-from-a-systematic-review-and-meta-analysis
#14
Maamer Slimani, Julien S Baker, Foued Cheour, Lee Taylor, Nicola Luigi Bragazzi
The present systematic review and meta-analysis aimed to assess the perturbations in hormonal and psychological homeostasis in response to soccer match-play. These perturbations were explored according to match outcome (i.e., win versus loss), gender, type of contest (i.e., competitive versus non-competitive fixtures) and competitive level (i.e., novice versus high-level). The review was conducted according to the Population/Intervention or Exposure/Comparison/Outcome(s) (PICO) criteria and the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines...
2017: PloS One
https://www.readbyqxmd.com/read/29023325/performance-and-health-related-characteristics-of-male-athletes-using-marijuana
#15
Jonathon K Lisano, Jeremy D Smith, Alissa B Mathias, Matt Christensen, Peter Smoak, Kristina T Phillips, Colin J Quinn, Laura K Stewart
The influence of chronic marijuana use on the performance and health of physically active individuals has yet to be fully elucidated. The purpose of this study was to explore pulmonary function, aerobic and anaerobic fitness, strength, serum testosterone, cortisol, C-reactive protein (CRP), Δ-9-tetrahydrocannibinol (THC), 11-nor-9-carboxy-Δ-9-tetrahydrocannibinol (THC-COOH), and 11-hydroxy-Δ-9-tetrahydrocannibinol (THC-OH) concentrations in a physically active population either using or not using marijuana...
October 10, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29022899/transplanted-human-p75-positive-stem-leydig-cells-replace-disrupted-leydig-cells-for-testosterone-production
#16
Min Zhang, Jiancheng Wang, Chunhua Deng, Mei Hua Jiang, Xin Feng, Kai Xia, Weiqiang Li, Xingqiang Lai, Haipeng Xiao, Ren-Shan Ge, Yong Gao, Andy Peng Xiang
Previous studies have demonstrated that rodent stem Leydig cell (SLC) transplantation can partially restore testosterone production in Leydig cell (LC)-disrupted or senescent animal models, which provides a promising approach for the treatment of hypogonadism. Here, we isolated human SLCs prospectively and explored the potential therapeutic benefits of human SLC transplantation for hypogonadism treatment. In adult human testes, p75 neurotrophin receptor positive (p75(+)) cells expressed the known SLC marker nestin, but not the LC lineage marker hydroxysteroid dehydrogenase-3β (HSD3β)...
October 12, 2017: Cell Death & Disease
https://www.readbyqxmd.com/read/29022642/induction-of-puberty-with-human-chorionic-gonadotropin-hcg-followed-by-reversal-of-hypogonadotropic-hypogonadism-in-kallmann-syndrome
#17
Malgorzata Maria Pierzchlewska, Maciej Grzegorz Robaczyk, Ida Vogel
INTRODUCTION: Kallmann syndrome (KS) is a rare, congenital disorder combining hypogonadotropic hypogonadism (HH) due to GnRH-deficiency with anosmia. Traditionally thought to require lifelong therapy it turns out to be a reversible condition in some patients. CASE REPORT: We present a case of a 22-year old man with absent puberty due to KS, in whom genetic testing revealed heterozygosity for a mutation in the PROK2 gene. Pubertal development and virilisation was achieved by using human chorionic gonadotropin (hCG) injections followed by testosterone replacement...
October 12, 2017: Endokrynologia Polska
https://www.readbyqxmd.com/read/29020729/diagnosing-and-managing-androgen-deficiency-in-men
#18
Raveen Kaur Sandher, Jonathan Aning
Androgens play a crucial role in bone, muscle and fat metabolism, erythropoiesis and cognitive health. In men aged 40-79 years the incidence of biochemical deficiency and symptomatic hypogonadism is 2.1-5.7%. Decreased libido or reduced frequency and quality of erections, fatigue, irritability, infertility or a diminished feeling of wellbeing may be presenting complaints. However, a significant proportion of men with androgen deficiency will be identified when they present for unrelated concerns. Important factors to elicit from the history in addition to the presenting complaint include: a medical history of obesity, type 2 diabetes, systemic diseases or metabolic syndrome which all impact on testosterone physiology...
April 2017: Practitioner
https://www.readbyqxmd.com/read/29020683/combination-of-androgen-deprivation-therapy-and-salvage-radiotherapy-versus-salvage-radiotherapy-alone-for-recurrent-prostate-cancer-after-radical-prostatectomy
#19
Sangjun Yoo, Dalsan You, Young Seok Kim, Jun Hyuk Hong, Hanjong Ahn, Choung-Soo Kim
INTRODUCTION: To assess the value of androgen deprivation therapy (ADT) on salvage radiotherapy (RT) in post-prostatectomy recurrent prostate cancer patients, we compared the oncologic outcomes between patients receiving RT + ADT and those receiving RT alone. MATERIALS AND METHODS: We reviewed the records of patients diagnosed with prostate cancer between 1995 and 2011, including 93 patients who underwent salvage RT and 69 patients who underwent salvage RT + ADT...
October 12, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/29020437/does-testosterone-therapy-raise-the-risk-of-vte
#20
EDITORIAL
Jonathan Rees
No abstract text is available yet for this article.
December 2016: Practitioner
keyword
keyword
4121
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"