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https://www.readbyqxmd.com/read/27612219/esophageal-function-tests-are-not-helpful-in-symptoms-suspicious-of%C3%A2-extraesophageal-reflux-a-prospective-study-in-74-patients
#1
T Frieling, R Kuhlbusch-Zicklam, C Weingardt, J Heise, C Kreysel, M Blank, D Müller
BACKGROUND/AIMS: Symptoms suspicious of extraesophageal reflux (SSEER) include globus, chronic cough, mucous obstruction and hoarseness. Reports of conventional esophageal function tests and measurement of extraesophageal reflux (EER) in these patients are spare providing conflicting results. METHODS: In a prospective study we evaluated 60 patients with SSEER by esophageal function tests (esophageal manometry, combined 24 h pH - metry - impedance and oropharyngeal pH measurement, Dx - pH measurement) and esophagogastroduodenoscopy (EGD)...
September 2016: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/27592124/24-h-multichannel-intraluminal-impedance-ph-metry-1%C3%A2-year-after-laparocopic-sleeve-gastrectomy-an-objective-assessment-of-gastroesophageal-reflux-disease
#2
Doulami Georgia, Triantafyllou Stamatina, Natoudi Maria, Albanopoulos Konstantinos, Filis Konstantinos, Leandros Emmanouil, Zografos Georgios, Theodorou Dimitrios
INTRODUCTION: It is not yet clear if laparoscopic sleeve gastrectomy (LSG) causes newly onset gastroesophageal reflux (GERD) or worsens already existing GERD. This is due to the absence of prospective studies using objective assessment measures of GERD such as pH monitoring. Our study aims at assessing GERD 1-year post-LSG procedure for obesity. MATERIALS AND METHODS: Twelve asymptomatic obese patients were studied prospectively by using 24-h multichannel intraluminal impedance-pHmetry (MIIpH) pre- and 12 months post-LSG...
September 3, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27193974/laryngopharyngeal-reflux-in-children-with-chronic-otitis-media-with-effusion
#3
Anna Górecka-Tuteja, Izabela Jastrzębska, Jacek Składzień, Krzysztof Fyderek
BACKGROUND/AIMS: To evaluate the characteristic properties of laryngopharyngeal reflux (LPR) and gastroesophageal reflux (GER) in children with otitis media with effusion (OME) using 24-hour multichannel intraluminal impedance combined with dual-probe (pharyngeal and esophageal) pH-metry. METHODS: Children aged 7-10 years of age with OME underwent 24-hour multichannel intraluminal impedance pH-metry. The upper pH sensor was situated 1 cm above the upper esophageal sphincter, and the lower pH sensor was placed 3-5 cm above the lower esophageal sphincter...
July 30, 2016: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/27137138/the-role-of-combined-24-h-multichannel-intraluminal-impedance-ph-monitoring-in-the-evaluation-of-children-with-gastrointestinal-symptoms-suggesting-gastro-esophageal-reflux-disease
#4
I Hojsak, L Ivković, T Trbojević, I Pavić, O Jadrešin, Z Mišak, S Kolaček
BACKGROUND: The aim of this study was to determine the role of multichannel intraluminal impedance-pH (pH-MII) monitoring in the diagnosis of gastro-esophageal reflux disease (GERD) in children who presented with gastrointestinal (GI) symptoms in comparison with the results of pH-metry alone and endoscopy. METHODS: All children who underwent pH-MII monitoring due to GI symptoms, suggestive of GERD, from October 2013 to October 2015 in Children's Hospital Zagreb, were retrospectively enrolled in the study...
October 2016: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/26909230/esophageal-testing-what-we-have-so-far
#5
REVIEW
Nicola de Bortoli, Irene Martinucci, Lorenzo Bertani, Salvatore Russo, Riccardo Franchi, Manuele Furnari, Salvatore Tolone, Giorgia Bodini, Valeria Bolognesi, Massimo Bellini, Vincenzo Savarino, Santino Marchi, Edoardo Vincenzo Savarino
Gastroesophageal reflux disease (GERD) is a common disorder of the gastrointestinal tract. In the last few decades, new technologies have evolved and have been applied to the functional study of the esophagus, allowing for the improvement of our knowledge of the pathophysiology of GERD. High-resolution manometry (HRM) permits greater understanding of the function of the esophagogastric junction and the risks associated with hiatal hernia. Moreover, HRM has been found to be more reproducible and sensitive than conventional water-perfused manometry to detect the presence of transient lower esophageal sphincter relaxation...
February 15, 2016: World Journal of Gastrointestinal Pathophysiology
https://www.readbyqxmd.com/read/26803582/the-correlation-between-endoscopic-reflux-esophagitis-and-combined-multichannel-intraluminal-impedance-ph-monitoring-in-children
#6
Yu-Wen Liu, Jia-Feng Wu, Huey-Ling Chen, Hong-Yuan Hsu, Mei-Hwei Chang, Wei-Chung Hsu, Ping-Huei Tseng, Hsiu-Po Wang, Yen-Hsuan Ni
BACKGROUND: Gastroesophageal reflux (GER) is the retrograde flow of gastric contents into the esophagus and may induce a variety of complications. Endoscopically visible breaks in the distal esophageal mucosa are the most reliable evidence of reflux esophagitis. Combined multichannel intraluminal impedance and pH-metry (MII-pH) is a technique that enables monitoring of GER independent of its acidity. The aim of this study is to investigate the GER patterns in children with the aid of MII-pH monitoring and determine the correlation between endoscopically proven reflux esophagitis and reflux types by MII-pH monitoring...
December 23, 2015: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/26285611/gastroesophageal-reflux-disease-in-children-with-cystic-fibrosis
#7
Marcin A Dziekiewicz, Aleksandra Banaszkiewicz, Agnieszka Urzykowska, Aleksandra Lisowska, Marta Rachel, Dorota Sands, Jaroslaw Walkowiak, Andrzej Radzikowski, Piotr Albrecht
Previously published studies have indicated that gastroesophageal reflux (GER) disease is common in pediatric patients with cystic fibrosis. The aim of the present study was to get insight into the incidence of GER and to characterize the nature of reflux episodes in children with cystic fibrosis. This was a multicenter, prospective study of children with cystic fibrosis older than 18 months. Forty four consecutive patients (22 boys, mean age 10.4 ± 3.6, range 3.0-17.8 years) were enrolled into the study...
2015: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/26003551/-normal-values-of-24h-multichannel-intraluminal-impedance-ph-metry-in-a-greek-obese-population-based-on-montreal-definition-of-gerd
#8
Georgia Doulami, Stamatina Triantafyllou, Maria Natoudi, Konstantinos Albanopoulos, Evangelos Menenakos, Konstantinos Filis, Georgios Zografos, Dimitrios Theodorou
BACKGROUND: Although several studies reporting normal values of 24h multichannel intraluminal impedance pH (MIIpH) have been published, none of them has ever studied obese individuals. The purpose of this study is to determine overall frequency and duration of reflux episodes (acid and non-acid, supine-upright, post and preprandial) in obese asymptomatic volunteers. METHODS: Obese volunteers were enlisted during their preoperative evaluation for bariatric surgery...
January 2016: Obesity Surgery
https://www.readbyqxmd.com/read/25840057/defective-upper-gastrointestinal-function-after-repair-of-combined-esophageal-and-duodenal-atresia
#9
Ana Catarina Fragoso, Ruben Ortiz, Francisco Hernandez, Pedro Olivares, Leopoldo Martinez, Juan A Tovar
BACKGROUND: Both esophageal atresia (EA) and duodenal atresia (DA) involve deficient anti-reflux barrier, poor esophageal function and eventually, duodenogastric reflux. This study aims at examining the upper gastrointestinal functional status in a cohort of patients with both EA and DA. METHODS: A retrospective survey of patients treated for EA and DA between 1965 and 2012 was conducted. Clinical charts, office visits, imaging, upper gastrointestinal endoscopy and esophageal pH metry/impedance were used to assess the long-term condition of the esophagus, the presence of gastroesophageal reflux disease (GERD) and/or the need for fundoplication...
April 2015: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/25824928/-ph-metry-impedance-24-hours-ph-metry
#10
Julio Pérez de la Serna y Bueno, Antonio Ruiz de León San Juan
No abstract text is available yet for this article.
April 2015: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/25668711/clinical-impact-of-esophageal-function-tests-and-argon-plasma-coagulation-in-heterotopic-gastric-mucosa-of-the-esophagus-and-extraesophageal-reflux-symptoms-a-prospective-study
#11
T Frieling, R Kuhlbusch-Zicklam, C Weingardt, J Heise, C Kreysel, M Blank, D Müller
BACKGROUND/AIMS: Globus, chronic cough, mucous obstruction and hoarseness are frequently interpreted and classified as manifestation of extraesophageal reflux (EER) or laryngopharyngeal reflux (LPR). Recent studies have indicated that ablation of heterotopic gastric mucosa of the proximal esophagus (HGMPE) by argon plasma coagulation (APC) significantly reduces EER/LPR symptoms. METHODS: In a prospective study we evaluated 14 patients with HGMPE and EER/LPR symptoms by esophageal function testing (esophageal manometry, combined 24 h-pH-metry-impedance - oropharyngeal-pH measurement), standardized symptom questionnaire (visual analogue scales), and esophagealgastroduodenoscopy (EGD)...
February 2015: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/25272320/follow-up-after-ph-metry-and-ph-impedance-in-pediatric-gastroesophageal-reflux-disease
#12
Rachel J van der Pol, Marloes van den Ouweland, Clara M Loots, Yvan Vandenplas, Marc A Benninga, Michiel P van Wijk
OBJECTIVES: It is unclear how diagnostic tests for gastroesophageal reflux disease (GERD) in children relate to the course of symptoms during follow-up. METHODS: During 1 year, all children (ages 0-18 years), who underwent pH-metry and/or pH multichannel intraluminal impedance (MII), were included after written informed consent was obtained. pH-metry and pH-MII test characteristics, such as reflux index (RI, % time that esophageal pH < 4), were obtained from the measurements...
February 2015: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/25208949/correlation-between-oropharyngeal-ph-monitoring-and-esophageal-ph-impedance-monitoring-in-patients-with-suspected-gerd-related-extra-esophageal-symptoms
#13
G Mazzoleni, C Vailati, D G Lisma, P A Testoni, S Passaretti
BACKGROUND: 24-hour esophageal pH-impedance (pH-MII) is not totally reliable for laryngopharyngeal reflux (LPR). Oropharyngeal (OP) pH-monitoring with the Dx-pH probe may detect LPR better. The correlation between these two techniques is not thoroughly established. Aim of this study is to examine the correlation between OP pH-metry and esophageal pH-MII monitoring. METHODS: Thirty-six consecutive patients with suspected gastroesophageal reflux disease-related extra-esophageal symptoms were evaluated using 24-h OP-pH and concomitant esophageal pH-MII monitoring...
November 2014: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/25080836/association-between-gastroesophageal-reflux-and-pathologic-apneas-in-infants-a-systematic-review
#14
REVIEW
Marije J Smits, Michiel P van Wijk, Miranda W Langendam, Marc A Benninga, Merit M Tabbers
BACKGROUND: In infants, apneas can be centrally mediated, obstructive or both and have been proposed to be gastroesophageal reflux (GER) induced. Evidence for this possible association has never been systematically reviewed. PURPOSE: To perform a systematic review using PubMed, EMBASE and Cochrane databases to determine whether an association between GER and apnea in infants exists. Studies with n ≥ 10 infants, aged <12 months, were included. GER had to be studied by pH-metry or pH-impedancemetry...
November 2014: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/25030477/the-patterns-of-reflux-can-affect-regression-of-non-dysplastic-and-low-grade-dysplastic-barrett-s-esophagus-after-medical-and-surgical-treatment-a-prospective-case-control-study
#15
Salvatore Tolone, Paolo Limongelli, Marco Romano, Alessandro Federico, Giovanni Docimo, Roberto Ruggiero, Luigi Brusciano, Gianmattia Del Genio, Ludovico Docimo
BACKGROUND: To date, therapeutic guidelines and pattern of reflux for patients with no-dysplasia (ND) or low-grade dysplasia (LGD) Barrett's esophagus (BE) remain unclear. We aimed to analyze pattern of reflux and regression of ND- or LGD-BE after medical and surgical treatment. METHODS: We studied a cohort of ND- and LGD-BE patients who underwent laparoscopic total fundoplication and a cohort of ND- and LGD-BE patients managed medically. Patients were matched for age, sex, and disease duration...
March 2015: Surgical Endoscopy
https://www.readbyqxmd.com/read/24834281/findings-of-impedance-ph-monitoring-in-patients-with-atypical-gastroesophageal-reflux-symptoms
#16
Mojgan Forootan, Maryam Ardeshiri, Nahid Etemadi, Nakisa Maghsoodi, Sara Poorsaadati
AIM: This study was designed to investigate about findings of Impedance pH-monitoring in patients with atypical symptoms of GERD. BACKGROUND: The routine treatment with proton pump inhibitors is not very effective in patients with atypical symptoms of Gastro-Esophageal Reflux Disease (GERD). It may be due to non-acid reflux which cannot be monitored using common methods such as pH-metry. Therefore, in these patients combinational procedure of multi channel intraluminal impedance and pH monitoring has been suggested as a new approach...
2013: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/24744591/positive-predictors-for-gastroesophageal-reflux-disease-and-the-therapeutic-response-to-proton-pump-inhibitors
#17
Valentin Becker, Stefan Grotz, Christoph Schlag, Simon Nennstiel, Analena Beitz, Bernhard Haller, Roland M Schmid, Alexander Meining, Monther Bajbouj
AIM: To identify objective and subjective predictors for the reliable diagnosis of gastroesophageal reflux disease (GERD) and the response to proton pump inhibitor (PPI) therapy. METHODS: Retrospectively, 683 consecutive patients suspected for GERD who underwent pH-metry/impedance measurement (pH/MII) were analyzed. All patients had previously undergone standard PPI treatment (e.g., pantoprazole 40 mg/d or comparable). Four hundred sixty patients were at least 10 d off PPIs (group A), whereas 223 patients were analyzed during their ongoing PPI therapy (group B)...
April 14, 2014: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/24619293/effect-of-sleeve-gastrectomy-on-gastroesophageal-reflux
#18
Jan S Burgerhart, Charlotte A I Schotborgh, Erik J Schoon, Johannes F Smulders, Paul C van de Meeberg, Peter D Siersema, André J P M Smout
Laparoscopic sleeve gastrectomy (LSG) is effective as a stand-alone bariatric procedure. Despite its positive effect with regard to weight loss and improvement of obesity-related co-morbidities, some patients develop gastroesophageal reflux symptoms postoperatively. The pathogenesis of these symptoms is not completely understood. Hence, this study aimed to assess the effect of sleeve gastrectomy on acid and non-acid gastroesophageal reflux, reflux symptoms and esophageal function. In a prospective study, patients underwent esophageal function tests (high-resolution manometry (HRM) and 24-h pH/impedance metry) before and 3 months after LSG...
September 2014: Obesity Surgery
https://www.readbyqxmd.com/read/24314192/esophageal-atresia-gastroesophageal-functional-follow-up-in-5-15-year-old-children
#19
Rikke Neess Pedersen, Simone Markøw, Søren Kruse-Andersen, Niels Qvist, Tine Plato Hansen, Oke Gerke, Rasmus Gaardskær Nielsen, Lars Rasmussen, Steffen Husby
PURPOSE: Esophageal atresia (EA) is one of the most frequent congenital alimentary tract anomalies with a considerable morbidity throughout childhood. This study evaluates the gastroesophageal problems in 5-15 year old children with EA and aims to identify factors predisposing to esophagitis in EA. MATERIAL AND METHODS: Fifty-nine patients primarily operated at Odense University Hospital, Denmark, during 1993-2005 were included in this follow-up study. The patients underwent the following examinations: Interview, upper endoscopy, endoscopic ultrasonography, high-resolution esophageal manometry (HREM), and pH- and multichannel intraluminal impedance (MII) measurements...
December 2013: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/24065062/diagnosis-of-gastroesophageal-reflux-and-anti-reflux-procedures-among-polish-children-with-gastrostomies-a-10-year-nationwide-analysis
#20
E Toporowska-Kowalska, B Gębora-Kowalska, W Fendler, K Popińska, A Szlagatys-Sidorkiewicz, U Grzybowska-Chlebowczyk, A Wiernicka, A Borkowska, M Sibilska, S Więcek, E Hapyn, J Kierkuś
BACKGROUND/OBJECTIVES: To analyse the approach to diagnose gastroesophageal reflux (GER) and the qualification criteria for anti-reflux (AR) procedures in Polish children fed via gastrostomy between 2000 and 2010. SUBJECTS/METHODS: An electronic questionnaire containing questions on the demographic and clinical data of patients with gastrostomies was distributed to six Polish centres of nutritional therapy. The portion pertaining to GER included data on clinical exponents, diagnostic procedures (pH-metry, pH-impedance, scintigraphy and upper gastrointestinal (GI) series) and AR...
November 2013: European Journal of Clinical Nutrition
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