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Sergey Leshchinskiy, Naiim Ali, Dmitriy Akselrod
No abstract text is available yet for this article.
February 15, 2018: Abdominal Radiology
Yabo Wang, Kai Zhu, Xiaochuan Zhang, Hongwei Ji
Intracellular ice formation (IIF) is the major cause of death in cells subjected to freezing. The occurrence of intracellular ice prevents the penetration of light into the camera and makes the image dark. Therefore, the gray-level variation can reflect the IIF. However, cell deformation is accompanied with IIF, especially for larger cells. It is necessary to account this entire phenomenon together in a single method. In this paper, the normalized parameter C defined by the gray-level variation depending on the displacement was defined to reflect the gray-level change of each pixel point in the region of interest of the image...
February 12, 2018: Cryobiology
Andrew J Stollenwerk, Eric Clausen, Matthew Cook, Keith Doore, Ryan Holzapfel, Jacob Weber, Rui He, Timothy E Kidd
Ultrasonic agitation is a proven method for breaking down layered materials such as MoS2 into single or few layer nanoparticles. In this experiment, MoS2 powder is sonicated in isopropanol for an extended period of time in an attempt to create particles of the smallest possible size. As expected, the process yielded a significant quantity of nanoscale MoS2 in the form of finite layer sheets with lateral dimensions as small as a few tens of nanometers. Although no evidence was found to indicate a larger the longer sonication times resulted in a significant increase in yield of single layer MoS2, the increased sonication did result in the formation of several types of carbon allotropes in addition to the sheets of MoS2...
May 1, 2018: Journal of Nanoscience and Nanotechnology
Thomas Colley, Gurpreet Sehra, Anuradha Chowdhary, Alexandre Alanio, Steven L Kelly, Yasuo Kizawa, Darius Armstrong-James, Matthew C Fisher, Andrew G S Warrilow, Josie E Parker, Diane E Kelly, Genki Kimura, Yuki Nishimoto, Mihiro Sunose, Stuart Onions, Damien Crepin, Franz Lagasse, Matthew Crittall, Jonathan Shannon, Matthew McConville, John King-Underwood, Alan Naylor, Stéphane Bretagne, John Murray, Kazuhiro Ito, Pete Strong, Garth Rapeport
The antifungal effects of the novel triazole, PC1244, designed for topical or inhaled administration, against A. fumigatus have been tested in a range of in vitro and in vivo studies. PC1244 demonstrated potent antifungal activities against clinical A. fumigatus isolates (N=96) with a MIC range of 0.016--0.25 μg/ml, whereas the MIC range for voriconazole was 0.25--0.5 μg/ml. PC1244 was a strong tight-binding inhibitor of recombinant A. fumigatus CYP51A and CYP51B (sterol 14α-demethylase) enzymes and strongly inhibited ergosterol synthesis in A...
February 12, 2018: Antimicrobial Agents and Chemotherapy
Florian Härtig, Marlene Ross, Nele Maria Dammeier, Nadin Fedtke, Bianka Heiling, Hubertus Axer, Bernhard F Décard, Eva Auffenberg, Marilin Koch, Tim W Rattay, Markus Krumbholz, Antje Bornemann, Holger Lerche, Natalie Winter, Alexander Grimm
As reliable biomarkers of disease activity are lacking, monitoring of therapeutic response in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) remains a challenge. We sought to determine whether nerve ultrasound and electrophysiology scoring could close this gap. In CIDP patients (fulfilling EFNS/PNS criteria), we performed high-resolution nerve ultrasound to determine ultrasound pattern sum scores (UPSS) and predominant echotexture nerve conduction study scores (NCSS) as well as Medical Research Council sum scores (MRCSS) and inflammatory neuropathy cause and treatment disability scores (INCAT) at baseline and after 12 months of standard treatment...
February 12, 2018: Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics
Ihsène Taihi, Loredana Radoi
Chronic non-suppurative osteomyelitis (CNSO) is a chronic bone disease and may be associated with a reparative periosteum entity called proliferative periostitis (PP). This condition rarely affects the maxillofacial region. Mandibular cases were already described for an infectious dental cause, often with an "onion skin" radiographic aspect, but some rare reported cases showed no obvious etiology. They represent a challenge for diagnosis because of possible misdiagnosis leading to unsuccessful or inappropriate treatment attempts...
February 12, 2018: Quintessence International
Subhasree Ray, Rakesh Sharma, Vipin Chandra Kalia
Polyhydroxyalkanoate (PHA) production by Bacillus thuringiensis EGU45 and defined mixed culture of Bacillus spp. were studied by using crude glycerol (CG) and hydrolyzed biowastes as feed material. Hydrolysates from onion peels (OP), potato peels, pea-shells (PS), apple pomace 2% total solids obtained with defined mixed hydrolytic cultures (MHC2) were inoculated with B. thuringiensis EGU45 and defined mixed bacterial cultures (5MC1), which produced PHA at the rate of 40-350 and 65-450 mg/L, respectively. Addition of CG (1%, v/v) to these hydrolysates resulted in 1...
March 2018: Indian Journal of Microbiology
Sara Desideri, Karen L Onions, Yan Qiu, Raina D Ramnath, Matthew J Butler, Christopher R Neal, Matthew L R King, Andrew E Salmon, Moin A Saleem, Gavin I Welsh, C Charles Michel, Simon C Satchell, Andrew H J Salmon, Rebecca R Foster
Increased urinary albumin excretion is a key feature of glomerular disease but has limitations as a measure of glomerular permeability. Here we describe a novel assay to measure the apparent albumin permeability of single capillaries in glomeruli, isolated from perfused kidneys cleared of red blood cells. The rate of decline of the albumin concentration within the capillary lumen was quantified using confocal microscopy and used to calculate apparent permeability. The assay was extensively validated and provided robust, reproducible estimates of glomerular albumin permeability...
February 9, 2018: Kidney International
Guang Liu, Rui Yao, Yong Zhao, Muheng Wang, Na Li, Yibing Li, Xin Bo, Jinping Li, Chuan Zhao
The rational modulation of composition and structure is critical for the development of robust and efficient oxygen evolution reaction (OER) catalysts for water splitting. In this study, an onion-like N-doped carbon nanorods hybrid (denoted as ONC) with encapsulated Ni/Fe3O4 heterostructures has been fabricated by the pyrolysis of an NiFe-based coordination polymer under a N2 atmosphere. The nanorod-like morphology is transferred from the polymer to the hybrids and generates ONC nanolayers encapsulated with core-shell Ni/Fe3O4 nanostructures...
February 9, 2018: Nanoscale
David Onion, Mark Isherwood, Naveen Shridhar, Mikalena Xenophontos, Madeleine L Craze, Laura J Day, María A García-Márquez, Robert G Pineda, Alexander M Reece-Smith, John H Saunders, John P Duffy, Richard H Argent, Anna M Grabowska
The complex interplay of the tumour microenvironment (TME) and its role in disease progression and response to therapy is poorly understood. The majority of studies to date focus on individual components or molecules within the TME and so lack the power correlative analysis. Here we have performed a multi-parameter analysis of the TME in 62 resectable non-small cell lung cancer (NSCLC) specimens detailing number and location of immune infiltrate, assessing markers of cancer-associated fibroblasts, caveolin-1 and tenascin-C, and correlating with clinicopathological details, as well as markers of disease progression such as epithelial-to-mesenchymal transition (EMT)...
January 5, 2018: Oncotarget
Qiaoling Yuan, Ce Song, Luyao Gao, Huihui Zhang, Cuicui Yang, Jie Sheng, Jian Ren, Dian Chen, Yong Wang
Onion (Allium cepa L.) is one of the major vegetables in China and accounts for a large proportion of China's vegetable exports. Onion cytoplasmic male sterility, which is often used in onion breeding, is caused by the interaction between the nuclear genes and the cytoplasm. However, the underlying molecular mechanism of onion cytoplasmic male sterility remains unclear. In this study, we analysed the anther microstructure of the onion cytoplasmic male sterile line SA2 and the onion maintainer line SB2. We found that the pollen abortion in SA2 occurred at the tetrad stage during the microspore development, which was very different from that in SB2...
January 31, 2018: Plant Physiology and Biochemistry: PPB
Daniel Wright, Erik Feibert, Stuart Reitz, Clint Shock, Joy Waite-Cusic
The Produce Safety Rule of the U.S. Food Safety Modernization Act includes restrictions on the use of agricultural water of poor microbiological quality. Mitigation options for poor water quality include the application of an irrigation-to-harvest interval of <4 days; however, dry bulb onion production includes an extended irrigation-to-harvest interval (<30 days). This study evaluated conventional curing practices for mitigating Escherichia coli contamination in a field setting. Well water inoculated with rifampin-resistant E...
February 7, 2018: Journal of Food Protection
D Medranda, J Borowiec, Xiao Zhang, S Wang, K Yan, J Zhang, Y He, S Ivaturi, F S Boi
A key challenge in the fabrication of ferromagnetically filled carbon nano-onions (CNOs) is the control of their thickness, dimensions and electric properties. Up to now literature works have mainly focused on the encapsulation of different types of ferromagnetic materials including α-Fe, Fe3C, Co, FeCo, FePd3 and others within CNOs. However, no report has yet shown a suitable method for controlling both the number of shells, diameter and electric properties of the produced CNOs. Here, we demonstrate an advanced chemical vapour deposition approach in which the use of small quantities of sulfur during the pyrolysis of ferrocene allows for the control of (i) the diameter of the CNOs, (ii) the number of shells and (iii) the electric properties...
January 2018: Royal Society Open Science
Ari Chae, Bo Ram Choi, Yujin Choi, Seongho Jo, Eun Bi Kang, Hyukjin Lee, Sung Young Park, Insik In
A novel mechanochemical method was firstly developed to synthesize carbon nanodots (CNDs) or carbon nano-onions (CNOs) through high-pressure homogenization of cellulose powders as naturrally abundant resource depending on the treatment times. While CNDs (less than 5 nm in size) showed spherical and amorphous morphology, CNOs (10-50 nm in size) presented polyhedral shape, and onion-like outer lattice structure, graphene-like interlattice spacing of 0.36 nm. CNOs showed blue emissions, moderate dispersibility in aqueous media, and high cell viability, which enables efficient fluorescence imaging of cellular media...
February 6, 2018: Nanotechnology
Ihsène Taihi, Loredana Radoi
Chronic non-suppurative osteomyelitis (CNSO) is a chronic bone disease and may be associated with a reparative periosteum entity called proliferative periostitis (PP). This condition rarely affects the maxillofacial region. Mandibular cases were already described for an infectious dental cause, often with an "onion skin" radiographic aspect, but some rare reported cases showed no obvious etiology. They represent a challenge for diagnosis because of possible misdiagnosis leading to unsuccessful or inappropriate treatment attempts...
2018: Quintessence International
Kenji Sakai, Marie Toudou, Yuuhi Shimura, Reyugo Teranishi, Shouhei Takaichi, Chihyon Son, Tomofumi Ohhashi, Hideki Osawa, Hiroshi Noro, Keigo Yasumasa, Takafumi Hirao, Teruo Iwasaki, Yoshikazu Morimoto, Nobutaka Hatanaka, Yoshio Yamasaki
A 70-year-old man was referred to our hospital and admitted after abdominal computed tomography(CT)examination revealed a tumor in the retroperitoneum. The specific blood test findings were poor, and surveillance CT demonstrated a wellcircumscribed, enhanced mass measuring 40mm with calcification behind the horizontal portion of the duodenum. The tumor presented with a slightly high signal in low signal, T2 in T1, and it showed a diffusion decrease in DWI; the simple abdominal MRIrevealed heterogeneous accumulation of SUVmax 3...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Tomoko Funakoshi, Noriyuki Kanzaki, Yuta Otsuka, Takayuki Izumo, Hiroshi Shibata, Shuichi Machida
Muscle satellite cells are committed myogenic progenitors capable of contributing to myogenesis to maintain adult muscle mass and function. Several experiments have demonstrated that muscle satellite cells can differentiate into adipocytes in vitro, supporting the mesenchymal differentiation potential of these cells. Moreover, muscle satellite cells may be a source of ectopic muscle adipocytes, explaining the lipid accumulation often observed in aged skeletal muscle (sarcopenia) and in muscles of patients` with diabetes...
March 2018: Biochemistry and Biophysics Reports
Dan-Ye Zhu, Yi-Long Ma, Kiran Thakur, Cai-Hong Wang, Hao Wang, Ya-Fei Ren, Jian-Guo Zhang, Zhao-Jun Wei
In this work we described the rheological properties of polysaccharides (HBSS, CHSS, DASS, CASS) sequentially extracted from onion (Allium cepa L.). Four onion polysaccharides (ACLPs) solutions resulted into significant differences on their rheological properties. ACLPs solutions showed non-Newtonian shear-thinning behavior over the range of 0.5-2.5%. At concentration of 1%, the apparent viscosity of CHSS was observed to be the highest. The apparent viscosity of ACLPs solutions decreased with the acidic pH (4...
January 25, 2018: International Journal of Biological Macromolecules
Hadi Emamat, Forough Foroughi, Hassan Eini-Zinab, Azita Hekmatdoost
It is well known that dietary intakes play a pivotal role in pathogenesis of nonalcoholic fatty liver disease (NAFLD)/nonalcoholic steatohepatitis (NASH); however, the role of each component of diet has not yet been elucidated. Our objective was to evaluate the effects of onion consumption on prevention of NAFLD/NASH development. Sprague-Dawley rats were fed either high-fat, high sugar diet (model group), or high-fat, high sugar diet plus 7% onion powder (model + onion), or chow diet ad libitum for 7 weeks...
January 2018: Indian Journal of Clinical Biochemistry: IJCB
Daun Seol, Jong-Sik Moon, Yujin Lee, Jiye Han, Daeil Jang, Dong-Jin Kang, Jiyoung Moon, Eunjin Jang, Jin-Woo Oh, Hoeil Chung
An M13 bacteriophage-based color sensor, which can change its structural color upon interaction with a gaseous molecule, was evaluated as a screening tool for the discrimination of the geographical origins of three different agricultural products (garlic, onion, and perilla). Exposure of the color sensor to sample odors induced the self-assembled M13 bacteriophage bundles to swell by the interaction of amino acid residues (repeating units of four glutamates) on the bacteriophage with the odor components, resulting in a change in the structural color of the sensor...
January 5, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
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