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https://www.readbyqxmd.com/read/28088393/discoid-skin-rash-in-a-preterm-infant
#1
Chun-Hua Liao, Chi-Nien Chen
No abstract text is available yet for this article.
January 12, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28064061/description-of-hyalodiscus-flabellus-sp-nov-vampyrellida-rhizaria-and-identification-of-its-bacterial-endosymbiont-candidatus-megaira-polyxenophila-rickettsiales-alphaproteobacteria
#2
Sebastian Hess
The genus Hyalodiscus Hertwig and Lesser, 1874 comprises naked freshwater amoebae with a unique set of characters, namely a vibrant orange-red colour, a discoid or fan-shaped morphology, and a characteristic rolling locomotion. Some species feed on the chloroplasts of green algae and were regarded as relatives of Vampyrella Cienkowski, 1865. However, because of striking morphological differences and the lack of molecular data, the exact relationship of Hyalodiscus to vampyrellids is still obscure. Here, I describe Hyalodiscus flabellus sp...
December 7, 2016: Protist
https://www.readbyqxmd.com/read/28060366/oral-lichenoid-lesions-distinguishing-the-benign-from-the-deadly
#3
Susan Müller
Oral lichen planus is a chronic inflammatory disease of unknown etiology or pathogenesis with varied disease severity that waxes and wanes over a long period of time. Although a common oral mucosal disease, accurate diagnosis is often challenging due to the overlapping clinical and histopathological features of oral lichen planus and other mucosal diseases. Other immune-mediated mucocutaneous diseases can exhibit lichenoid features including mucous membrane pemphigoid, chronic graft-versus-host disease, and discoid lupus erythematosus...
January 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/28050486/patch-test-as-a-diagnostic-tool-in-hand-eczema
#4
Natarajan Vigneshkarthik, Satyaki Ganguly, Sheela Kuruvila
INTRODUCTION: Allergic contact dermatitis is an important cause of hand eczema. Patch testing is the only investigation available to prove the diagnosis of allergic contact dermatitis. Exposures to allergens differ according to geographical, occupational, economic and social factors. Accordingly, patterns of allergic contact dermatitis differ in different parts of the world and different regions of the same country. AIM: To study the causes of allergic contact dermatitis in adult patients with hand eczema with the help of patch testing...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28045540/characterization-of-pegylated-liposomal-mitomycin-c-lipid-based-prodrug-promitil%C3%A2-by-high-sensitivity-differential-scanning-calorimetry-and-cryogenic-transmission-electron-microscopy
#5
Xiaohui Wei, Yogita Patil, Patricia Ohana, Yasmine Amitay, Hilary Shmeeda, Alberto Gabizon, Yechezkel Barenholz
The effect of a lipidated prodrug of mitomycin C (MLP) on the membrane of a pegylated liposome formulation (PL-MLP), also known as Promitil®, was characterized through high-sensitivity differential scanning calorimetry (DSC), and cryo-TEM. The thermodynamic analysis demonstrated that MLP led to the formation of heterogeneous domains in the membrane plane of PL-MLP. MLP concentrated in prodrug-rich domains, arranged in high-ordered crystal-like structures, as suggested by the sharp and high enthalpy endotherm in the 1st heating scanning...
January 3, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28024148/solution-structure-of-discoidal-high-density-lipoprotein-particles-with-a-shortened-apolipoprotein-a-i
#6
Stefan Bibow, Yevhen Polyhach, Cédric Eichmann, Celestine N Chi, Julia Kowal, Stefan Albiez, Robert A McLeod, Henning Stahlberg, Gunnar Jeschke, Peter Güntert, Roland Riek
High-density lipoprotein (HDL) particles are cholesterol and lipid transport containers. Mature HDL particles destined for the liver develop through the formation of intermediate discoidal HDL particles, which are the primary acceptors for cholesterol. Here we present the three-dimensional structure of reconstituted discoidal HDL (rdHDL) particles, using a shortened construct of human apolipoprotein A-I, determined from a combination of nuclear magnetic resonance (NMR), electron paramagnetic resonance (EPR) and transmission electron microscopy (TEM) data...
December 26, 2016: Nature Structural & Molecular Biology
https://www.readbyqxmd.com/read/28012004/post-operative-deformation-and-extrusion-of-the-discoid-lateral-meniscus-following-a-partial-meniscectomy-with-repair
#7
Tomohiko Matsuo, Kazutaka Kinugasa, Kousuke Sakata, Tomoki Ohori, Tatsuo Mae, Masayuki Hamada
PURPOSE: The purpose of this study was to investigate the morphology of the discoid lateral meniscus sequentially following a partial meniscectomy with repair using magnetic resonance imaging (MRI). METHODS: Nine patients with a symptomatic discoid lateral meniscus with a peripheral tear were enrolled in this study, and a partial meniscectomy with repair was performed arthroscopically. An MRI examination was performed 2 weeks after surgery (before weight bearing was permitted) and again 6 months after surgery (when sporting activities could resume)...
December 23, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/27976613/discoid-lupus-erythematosus-occurring-in-an-area-previously-affected-by-herpes-zoster-virus-wolf-s-isotopic-reaction
#8
Torkan Hirbod, Davide Altamura, Evdokia Arkoumani, Catherine M Stefanato, Roberto Verdolini
No abstract text is available yet for this article.
December 15, 2016: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/27968927/autoimmune-collagen-vascular-diseases-kids-are-not-just-little-people
#9
Sean Timpane, Heather Brandling-Bennett, Arni K Kristjansson
Morphea, dermatomyositis (DM), and discoid lupus erythematosus (DLE) are autoimmune collagen vascular diseases that can present at any age. In all three of these diseases, the tenants of diagnosis and treatment are largely the same in both children and adults, with a few notable differences. Children with morphea are more likely to present with the linear subtype and have a higher incidence of extracutaneous manifestations. Children often need early aggressive systemic treatment to try to prevent long-term sequelae of morphea...
November 2016: Clinics in Dermatology
https://www.readbyqxmd.com/read/27936135/identifying-major-transitions-in-the-evolution-of-lithic-cutting-edge-production-rates
#10
Antoine Muller, Chris Clarkson
The notion that the evolution of core reduction strategies involved increasing efficiency in cutting edge production is prevalent in narratives of hominin technological evolution. Yet a number of studies comparing two different knapping technologies have found no significant differences in edge production. Using digital analysis methods we present an investigation of raw material efficiency in eight core technologies broadly representative of the long-term evolution of lithic technology. These are bipolar, multiplatform, discoidal, biface, Levallois, prismatic blade, punch blade and pressure blade production...
2016: PloS One
https://www.readbyqxmd.com/read/27899354/collagenous-ultrastructure-of-the-discoid-meniscus-a-transmission-electron-microscopy-study
#11
Young-Hee Choi, Young-Jin Seo, Jong Mun Ha, Koo Hyun Jung, Jeehyoung Kim, Si Young Song
BACKGROUND: The collagen ultrastructure of the discoid lateral meniscus (DLM) has not been precisely defined. PURPOSE: To investigate the ultrastructure of the DLM, focusing on its collagen fibers, and to compare the collagen net architecture between intact and torn DLMs using the Collagen Meniscal Architecture (CMA) scoring system. STUDY DESIGN: Descriptive laboratory study. METHODS: Thirty specimens were taken from 30 patients with a diagnosis of a complete DLM using a 1-piece technique...
November 29, 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/27894182/medial-and-lateral-discoid-menisci-of-both-knees
#12
Hiroyuki Kan, Yuji Arai, Shuji Nakagawa, Hiroaki Inoue, Ginjiro Minami, Kazuya Ikoma, Hiroyoshi Fujiwara, Toshikazu Kubo
Discoid menisci on both the medial and lateral sides are rare, and there are very few reports on cases involving both sides. We report a case of a 52-year-old female with medial and lateral discoid menisci in both knees. Arthroscopy revealed the lateral menisci of both knees were complete discoid menisci, and partial meniscectomy was performed. The medial menisci were incomplete discoid menisci, but there were no findings of abnormal mobility or injury; therefore, the medial menisci were observed without treatment...
December 1, 2016: Knee Surgery & related Research
https://www.readbyqxmd.com/read/27894171/diagnosis-and-treatment-of-discoid-meniscus
#13
REVIEW
Jae-Gyoon Kim, Seung-Woo Han, Dae-Hee Lee
There is a greater incidence of discoid meniscus in Asian countries than in Western countries, and bilateral discoid menisci are also common. The discoid meniscus may be a congenital anomaly, and genetics or family history may play a role in the development of discoid menisci. Because the histology of discoid meniscus is different from that of normal meniscus, it is prone to tearing. Individuals with a discoid meniscus can be asymptomatic or symptomatic. Asymptomatic discoid menisci do not require treatment...
December 1, 2016: Knee Surgery & related Research
https://www.readbyqxmd.com/read/27871459/morphology-histochemistry-and-glycosylation-of-the-placenta-and-associated-tissues-in-the-european-hedgehog-erinaceus-europaeus
#14
Carolyn J P Jones, A M Carter, W R Allen, Sandra A Wilsher
INTRODUCTION: There are few descriptions of the placenta and associated tissues of the European hedgehog (Erinaceus europaeus) and here we present findings on a near-term pregnant specimen. METHODS: Tissues were examined grossly and then formalin fixed and wax-embedded for histology and immunocytochemistry (cytokeratin) and resin embedded for lectin histochemistry. RESULTS: Each of four well-developed and near term hoglets displayed a discoid, haemochorial placenta with typical labyrinth and spongy zones...
December 2016: Placenta
https://www.readbyqxmd.com/read/27837547/stable-discoidal-bicelles-a-platform-of-lipid-nanocarriers-for-cellular-delivery
#15
Ying Liu, Yan Xia, Armin Tahmasbi Rad, Wafa Aresh, Mu-Ping Nieh
Bicellar mixtures have been used as alignable membrane substrates for the structural characterization of membrane-associated proteins. Most recently, it has been shown that bicelles can serve as nanocarriers to effectively deliver hydrophobic molecules to cancer cells with a 3- to 10-fold enhancement compared to that of chemically identical liposomes. In this chapter, a detailed preparation protocol, common structural characterization methods, the structural stability and the cellular uptake of bicellar nanodisks are discussed...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27837197/comparison-of-ethnicity-gender-age-of-onset-and-outcome-in-south-africans-with-systemic-lupus-erythematosus
#16
A Budhoo, G M Mody, T Dubula, N Patel, P G Mody
Ethnicity, gender and age of onset are reported to influence the expression and outcome of systemic lupus erythematosus. We studied a multi-ethnic cohort of 408 South Africans (91.2% females) comprising 237 (58.1%) Indians, 137 (33.6%) African Blacks, 17 (4.2%) Mixed ethnicity and 17 (4.2%) Whites. The most common manifestations were arthritis (80.6%), photosensitivity (67.2%), oral ulcers (50.0%), malar rash (49.0%) and renal (39.2%). The common laboratory findings were positive anti-nuclear factor (96.8%), haematological (74...
November 10, 2016: Lupus
https://www.readbyqxmd.com/read/27837194/lenalidomide-for-refractory-cutaneous-manifestations-of-pediatric-systemic-lupus-erythematosus
#17
E Y Wu, L E Schanberg, E C Wershba, C E Rabinovich
OBJECTIVE: Cutaneous manifestations of pediatric systemic lupus erythematosus cause significant morbidity. Lenalidomide, a thalidomide analogue, has shown promise treating cutaneous lupus erythematosus in adults. Our objective was to evaluate lenalidomide's efficacy and safety in treating refractory cutaneous manifestations of pediatric systemic lupus erythematosus. METHODS: We performed a retrospective chart review of 10 adolescents who received lenalidomide for recalcitrant cutaneous lupus erythematosus...
November 10, 2016: Lupus
https://www.readbyqxmd.com/read/27833770/double-layered-lateral-meniscus-in-an-8-year-old-child-report-of-a-rare-case
#18
Susumu Araki, Mitsuhiko Kubo, Kosuke Kumagai, Shinji Imai
Reports of congenital abnormalities of the lateral meniscus include discoid meniscus, accessory meniscus, double-layered meniscus, and ring-shaped meniscus. Particularly, only a few cases of double-layered meniscus have been reported. We report a case of double-layered lateral meniscus, in which an additional semicircular meniscus was observed under the normal lateral meniscus. The accessory hemimeniscus was resected by means of arthroscopic surgery. This case demonstrates an interesting and extremely rare anatomical abnormality of the lateral meniscus...
2016: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/27829463/frequency-and-predictors-of-the-lupus-low-disease-activity-state-in-a-multi-national-and-multi-ethnic-cohort
#19
Vera Golder, Rangi Kandane-Rathnayake, Alberta Yik-Bun Hoi, Molla Huq, Worawit Louthrenoo, Yuan An, Zhan Guo Li, Shue Fen Luo, Sargunan Sockalingam, Chak Sing Lau, Alfred Lok Lee, Mo Yin Mok, Aisha Lateef, Kate Franklyn, Susan Morton, Sandra Teresa V Navarra, Leonid Zamora, Yeong-Jian Wu, Laniyati Hamijoyo, Madelynn Chan, Sean O'Neill, Fiona Goldblatt, Eric Francis Morand, Mandana Nikpour
BACKGROUND: Systemic lupus erythematosus (SLE) is a chronic heterogeneous disease with considerable burden from disease activity and damage. A novel clinical treatment target in the form of the lupus low disease activity state (LLDAS) has been recently reported, with retrospective validation showing that time spent in LLDAS translates to reduced damage accrual. The objectives of this study were to describe the frequency and identify the predictors of attaining LLDAS in a large multinational cohort of patients with SLE...
November 9, 2016: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/27811758/range-extension-of-pseudotorinia-phorcysi-gastropoda-architectonicidae-%C3%A2-from-the-sw-atlantic-with-remarks-on-its-ontogeny
#20
Daniel C Cavallari, Rodrigo B Salvador
Architectonicidae is a diverse family of heterobranch sea snails comprising over 11 genera and 140 extant species distributed worldwide (Bieler & Petit, 2005). They live in shallow to deep water, and have turbinate to discoidal shells, with a typically wide umbilicus and a downward-pointing (heterostrophic) protoconch (Healy, 1998). Pseudotorinia phorcysi Cavallari, Salvador & Simone, 2013 is a deep-water species known only from its type locality in the SW Atlantic, off Cabo Frio, Rio de Janeiro state, Brazil (23°41'S 42°06'W, 430-450 m depth)...
October 17, 2016: Zootaxa
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