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https://www.readbyqxmd.com/read/28229984/anatomical-knee-variants-in-discoid-lateral-meniscal-tears
#1
Xu-Xu Chen, Jian Li, Tao Wang, Yang Zhao, Hui Kang
BACKGROUND: Discoid lateral meniscus was a common meniscal dysplasia and was predisposed to tear. There were some anatomical knee variants in patients with discoid lateral meniscus. The aim of this study was to analyze the relationship between anatomical knee variants and discoid lateral meniscal tears. METHODS: There were totally 125 cases of discoid lateral meniscus enrolled in this study from February 2008 to December 2013. Eighty-seven patients who underwent arthroscopic surgery for right torn discoid lateral meniscus were enrolled in the torn group...
2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28197693/predictive-factors-for-osteochondritis-dissecans-of-the-lateral-femoral-condyle-concurrent-with-a-discoid-lateral-meniscus
#2
Junsei Takigami, Yusuke Hashimoto, Tomohiro Tomihara, Shinya Yamasaki, Koji Tamai, Kyoko Kondo, Hiroaki Nakamura
PURPOSE: Osteochondritis dissecans (OCD) of the lateral femoral condyle is relatively rare, and it is often reported in combination with discoid lateral meniscus. However, little is known about the mechanism underlying this connection. Predictive factors for OCD coinciding with discoid lateral meniscus in Japanese children and adolescents were assessed. METHODS: During 2000-2015, 152 knees in 133 patients aged 5-15 years were diagnosed with symptomatic complete discoid lateral meniscus...
February 14, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28196317/common-skin-conditions-in-children-noninfectious-rashes
#3
Brian Z Rayala, Dean S Morrell
Cutaneous adverse drug reactions are among the most common noninfectious rashes of childhood. Cutaneous adverse drug reactions are classified as morbilliform, urticarial, bullous, pustular, or psoriasiform. Atopic dermatitis is one of the most common inflammatory cutaneous eruptions, and is characterized by pruritus and flexural distribution. Emollients and topical corticosteroids are first-line therapies. Topical calcineurin inhibitors are second-line, steroid-sparing drugs for certain conditions, such as face and eyelid eczema...
February 2017: FP Essentials
https://www.readbyqxmd.com/read/28194816/verrucous-discoid-lupus-erythematosus-in-a-child
#4
F Topaloglu Demir, F Deniz, Y Ozben, I Kivanc Altunay
No abstract text is available yet for this article.
February 13, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28184992/association-study-between-the-tp53-rs1042522g-c-polymorphism-and-susceptibility-to-systemic-lupus-erythematosus-in-a-chinese-han-population
#5
Jie Yang, Ji-Min Zhu, Song Wu, Jing Li, Ming-Rui Wang, Ting-Ting Wang, Yu-Wei Lu
Tumour suppressor protein 53 (p53) plays a central role in apoptosis, cell proliferation and death. Previously studies found contribution of functional p53 Arg72Pro polymorphism (TP53 rs1042522G/C polymorphism) in the development of systemic lupus erythematosus (SLE) remains controversial. In this study, for the first time, we evaluated its association with SLE in a Chinese Han population. This case-control study enrolled 1470 SLE patients and 2283 healthy controls. The genotyping of TP53 rs1042522 polymorphism was determined by Sequenom Mass ARRAY technology...
February 9, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28170256/self-assembling-and-luminescent-properties-of-chiral-bis-oxadiazole-derivatives-in-solution-and-liquid-crystalline-phases
#6
Aneesh P Sivadas, D S Shankar Rao, N S Saleesh Kumar, Deepak D Prabhu, Shinto Varghese, Chelat Narayana Panicker Ramachandran, Rahul Mani Ongungal, Subbarao Krishna Prasad, Suresh Das
Herein, we report the synthesis, self-assembly and electroluminescence characteristics of a new green-emitting, pseudo discoid chiral molecule, OXDC containing an electron-donating stilbene core and an electron-accepting oxadiazole substituent. The helical organization and specific interaction of the chiral pseudo discoid molecule resulted in the formation of self-assembled nanofibres with columnar superstructure. A high performance organic light emitting device was demonstrated using OXDC as the emitting material, with a luminous intensity of 10115 cdm(2) at 5 V and chromaticity coordinates of (0...
February 7, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28164061/arthroscopic-meniscectomy-and-meniscoplasty-for-a-torn-discoid-medial-meniscus-case-report-surgical-technique-and-literature-review
#7
Gokhale Nikhil Abhay, Samant Ashwin, Shahane Sunil, Kapopara Hardik
INTRODUCTION: Normal menisci of the knee are semilunar structures. Sometimes, a meniscus may be found to be thickened and disc like and is called a discoid meniscus. Such a discoid variant is usually found in the lateral meniscus. Its occurrence in the medial meniscus is extremely rare. CASE REPORT: We report a case of an 18-year-old female, who presented to us with knee pain and was found to have a discoid medial meniscus with a tear. We operated on her arthroscopically and performed meniscectomy and meniscoplasty...
September 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28164045/ipsilateral-medial-and-lateral-discoid-meniscus-with-medial-meniscus-tear
#8
Kengo Shimozaki, Junsuke Nakase, Yoshinori Ohashi, Hitoaki Numata, Takeshi Oshima, Yasushi Takata, Hiroyuki Tsuchiya
INTRODUCTION: Discoid meniscus is a well-documented knee pathology, and there are many cases of medial or lateral discoid meniscus reported in the literature. However, ipsilateral concurrent medial and lateral discoid meniscus is very rare, and only a few cases have been reported. Herein, we report a case of concurrent medial and lateral discoid meniscus. CASE REPORT: A 27-year-old Japanese man complained of pain on medial joint space in his right knee that was diagnosed as a complete medial and lateral discoid meniscus...
September 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28160013/high-tibial-osteotomy-accelerates-lateral-compartment-osteoarthritis-in-discoid-meniscus-patients
#9
Jatin Prakash, Eun-Kyoo Song, Hong An Lim, Young Joo Shin, Cheng Jin, Jong-Keun Seon
PURPOSE: The valgus high tibial osteotomy (HTO) in patients with medial osteoarthritis and discoid lateral meniscus can result in increased load on the lateral compartment and hence a higher chances of tear. This may accelerate the progression of osteoarthritis on lateral compartment. We, therefore, carried out the case control study with a hypothesis that an HTO would accelerate the progression of osteoarthritis (OA) on lateral compartment in patients with complete discoid meniscus. METHODS: The records of all patients with open wedge HTO from 2008 to 2012 were evaluated for complete lateral discoid meniscus...
February 3, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28133824/a-retrospective-study-comparing-histopathological-and-immunopathological-features-of-nasal-planum-dermatitis-in-20-dogs-with-discoid-lupus-erythematosus-or-leishmaniosis
#10
Michela De Lucia, Giorgia Mezzalira, Mar Bardagí, Dolors M Fondevila, Elisabetta Fabbri, Alessandra Fondati
BACKGROUND: In areas endemic for leishmaniosis, discoid lupus erythematosus (DLE) and canine leishmaniosis (CanL) are the most common differential diagnoses for nasal planum erosive-ulcerative dermatitis in dogs. HYPOTHESIS/OBJECTIVE: To compare histopathological and immunopathological features of canine nasal planum erosive-ulcerative dermatitis with depigmentation due to DLE or CanL. ANIMALS: Nasal planum biopsies from dogs with nasal planum loss of architecture, depigmentation, swelling, erosions or ulcerations due to DLE (n = 14) or CanL (n = 6)...
January 29, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28131036/morphological-description-of-two-new-ciliates-ciliophora-karyorelictea-cryptopharyngidae-apocryptopharynx-discoidalis-spec-nov-and-cryptopharynx-minutus-spec-nov
#11
Yuan Xu, Xinpeng Fan, Saleh A Al-Farraj, Xiaozhong Hu
The karyorelictids, a highly specialized group of ciliates, mostly inhabit marine biotopes, and there is very little information about their diversity, taxonomy, and systematics. The present paper investigates two new cryptopharyngid ciliates, Apocryptopharynx discoidalis spec. nov. and Cryptopharynx minutus spec. nov., which were isolated from the intertidal zone of Diaosuyuan Beach in Qingdao, China. Apocryptopharynx discoidalis spec. nov. can be distinguished from related species by its oval discoid body shape and highly structured epipellicular scales covering the left lateral surface...
December 2, 2016: European Journal of Protistology
https://www.readbyqxmd.com/read/28128538/proton-detected-solid-state-nmr-spectroscopy-of-a-zinc-diffusion-facilitator-protein-in-native-nanodiscs
#12
Beate Bersch, Jonas M Dörr, Audrey Hessel, J Antoinette Killian, Paul Schanda
The structure, dynamics, and function of membrane proteins are intimately linked to the properties of the membrane environment in which the proteins are embedded. For structural and biophysical characterization, membrane proteins generally need to be extracted from the membrane and reconstituted in a suitable membrane-mimicking environment. Ensuring functional and structural integrity in these environments is often a major concern. The styrene/maleic acid co-polymer has recently been shown to be able to extract lipid/membrane protein patches directly from native membranes to form nanosize discoidal proteolipid particles, also referred to as native nanodiscs...
February 20, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28127570/high-prevalence-of-metabolic-syndrome-in-patients-with-discoid-lupus-erythematosus-a-cross-sectional-case-control-study
#13
Sevgi Akarsu, Ozlem Ozbagcivan, Fatma Semiz, Sebnem Aktan
Although it is known that systemic form of lupus erythematosus (LE) and metabolic syndrome (MetS) are frequently observed together, there are no published reports on MetS in patients with skin-restricted LE. We aimed to compare the frequencies of MetS and its components in discoid LE (DLE) with the non-DLE control group. Additionally, we intended to determine the differences of sociodemographic and clinical data of the DLE patients with MetS compared to the patients without MetS. This was a cross-sectional, case-control study, including 60 patients with DLE and 82 age- and gender-matched control subjects...
2017: Journal of Immunology Research
https://www.readbyqxmd.com/read/28118884/iningainema-pulvinus-gen-nov-sp-nov-cyanobacteria-scytonemataceae-a-new-nodularin-producer-from-edgbaston-reserve-north-eastern-australia
#14
Glenn B McGregor, Barbara C Sendall
A new nodularin producing benthic cyanobacterium Iningainema pulvinus gen nov., sp nov. was isolated from a freshwater ambient spring wetland in tropical, north-eastern Australia and characterised using combined morphological and phylogenetic attributes. It formed conspicuous irregularly spherical to discoid, blue-green to olive-green cyanobacterial colonies across the substratum of shallow pools. Morphologically Iningainema is most similar to Scytonematopsis Kiseleva and Scytonema Agardh ex Bornet & Flahault...
February 2017: Harmful Algae
https://www.readbyqxmd.com/read/28118537/pharmacodynamics-safety-and-clinical-efficacy-of-amg-811-a-human-anti-interferon-%C3%AE-antibody-in-subjects-with-discoid-lupus-erythematosus
#15
Victoria P Werth, David Fiorentino, Barbara A Sullivan, Michael J Boedigheimer, Kit Chiu, Christine Wang, Gregory E Arnold, Michael A Damore, Jeannette Bigler, Andrew A Welcher, Chris B Russell, David A Martin, James B Chung
OBJECTIVE: Interferon (IFN)-γ is implicated in the pathogenesis of discoid lupus erythematosus (DLE). This study evaluated a single dose of AMG 811, an anti-IFN-γ antibody, in subjects with DLE. METHODS: This was a phase 1, randomized, double-blind, placebo-controlled, crossover study (sequence 1: AMG 811 followed by placebo; sequence 2: placebo followed by AMG 811). Subjects received a single subcutaneous dose of AMG 811 (180 mg) or placebo. Pharmacodynamic endpoints included global transcriptional analyses of lesional and nonlesional skin, IFN-γ Blockade Signature (IGBS) transcriptional score in skin and blood, keratinocyte IFN-γ RNA score, and serum CXCL-10 protein...
January 24, 2017: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/28114702/discoid-lateral-meniscus
#16
Wen-Li Dai, Hua Zhang, Ai-Guo Zhou, Gang Zhang, Jian Zhang
Partial and total meniscectomies are the most common treatments for patients with discoid lateral meniscus (DLM). We conducted this study to quantitatively assess and compare the outcomes of partial and total meniscectomies for DLM. We also assessed whether the outcomes differed by the type of DLM, duration of follow-up, and age of patients. We searched PubMed, Embase, and the Cochrane database to identify relevant studies that reported outcomes, including Ikeuchi grade, the International Knee Documentation Committee (IKDC) Subjective Knee score, Lysholm score, or failure rate, in patients who underwent partial and total meniscectomies...
January 23, 2017: Journal of Knee Surgery
https://www.readbyqxmd.com/read/28112988/platelet-bioreactor-accelerated-evolution-of-design-and-manufacture
#17
Jonathan N Thon, Brad J Dykstra, Lea M Beaulieu
Platelets, responsible for clot formation and blood vessel repair, are produced by megakaryocytes in the bone marrow. Platelets are critical for hemostasis and wound healing, and are often provided following surgery, chemotherapy, and major trauma. Despite their importance, platelets today are derived exclusively from human volunteer donors. They have a shelf life of just five days, making platelet shortages common during long weekends, civic holidays, bad weather, and during major emergencies when platelets are needed most...
January 23, 2017: Platelets
https://www.readbyqxmd.com/read/28088393/discoid-skin-rash-in-a-preterm-infant
#18
Chun-Hua Liao, Chi-Nien Chen
No abstract text is available yet for this article.
January 12, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28064061/description-of-hyalodiscus-flabellus-sp-nov-vampyrellida-rhizaria-and-identification-of-its-bacterial-endosymbiont-candidatus-megaira-polyxenophila-rickettsiales-alphaproteobacteria
#19
Sebastian Hess
The genus Hyalodiscus Hertwig and Lesser, 1874 comprises naked freshwater amoebae with a unique set of characters, namely a vibrant orange-red colour, a discoid or fan-shaped morphology, and a characteristic rolling locomotion. Some species feed on the chloroplasts of green algae and were regarded as relatives of Vampyrella Cienkowski, 1865. However, because of striking morphological differences and the lack of molecular data, the exact relationship of Hyalodiscus to vampyrellids is still obscure. Here, I describe Hyalodiscus flabellus sp...
December 7, 2016: Protist
https://www.readbyqxmd.com/read/28060366/oral-lichenoid-lesions-distinguishing-the-benign-from-the-deadly
#20
Susan Müller
Oral lichen planus is a chronic inflammatory disease of unknown etiology or pathogenesis with varied disease severity that waxes and wanes over a long period of time. Although a common oral mucosal disease, accurate diagnosis is often challenging due to the overlapping clinical and histopathological features of oral lichen planus and other mucosal diseases. Other immune-mediated mucocutaneous diseases can exhibit lichenoid features including mucous membrane pemphigoid, chronic graft-versus-host disease, and discoid lupus erythematosus...
January 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
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