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https://www.readbyqxmd.com/read/29333775/-effect-of-dexmedetomidine-on-emergence-agitation-after-general-anesthesia-in-children-undergoing-odontotherapy-in-day-surgery-operating-room
#1
Luo Lin, Zhang Yueming, Li Meisheng, Wang Jiexue, Ji Yang
OBJECTIVE: To study the effectiveness of dexmedetomidine used for general anesthesia maintenance in children undergoing odontotherapy in day-surgery operating room in reducing the incidence of emergence agitation (EA). METHODS: Eighty children undergoing odontotherapy and under general anesthesia in day-surgery operating room were randomized into two groups, group A (n=40) and group B (n=40). Each patient in group A was administered with a bolus dose of dexmedetomidine (1...
December 1, 2017: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/29333567/predictors-for-intracranial-hemorrhage-following-intravenous-thrombolysis-in-posterior-circulation-stroke
#2
Dorňák Tomáš, Král Michal, Sedláčková Zuzana, Šaňák Daniel, Čecháková Eva, Divišová Petra, Zapletalová Jana, Kaňovský Petr
Intravenous thrombolysis (IVT) is a standard treatment for anterior (ACS) and posterior circulation stroke (PCS). However, due to the low occurrence of PCS and of intracranial hemorrhage (ICH) in PCS, the knowledge about ICH predictors following IVT in PCS is sparse. Our aim was to identify predictors for ICH following IVT in PCS. The set consisted of 1281 consecutive ischemic stroke (IS) patients treated with IVT, out of which 158 (103 males; mean age 65.6 ± 12.3 years) had PCS. Collected data include baseline characteristics, common stroke risk factors, pre-medication, stroke severity, admission blood glucose level, blood pressure and treatment with intravenous antihypertensive therapy before and during IVT, occlusion of arteries, recanalization rate, time to treatment, and clinical outcome at day 90...
January 15, 2018: Translational Stroke Research
https://www.readbyqxmd.com/read/29332774/an-analysis-of-intoxicated-patients-transported-by-a-doctor-helicopter
#3
Ikuto Takeuchi, Kazuhiko Omori, Hiroki Nagasawa, Kei Jitsuiki, Takashi Iso, Akihiko Kondo, Kouhei Ishikawa, Hiromichi Ohsaka, Youichi Yanagawa
OBJECTIVE: We retrospectively investigated all of the intoxicated patients who were transported by a doctor helicopter (DH) in eastern Shizuoka between April 2004 and December 2015 to determine when air medical transport was used in cases of toxic exposure. METHODS: Subjects were divided into 2 groups: an outpatient group of subjects who went home after receiving a medical evaluation and treatment and an admission group. RESULTS: The outpatient and admission groups included 17 and 31 subjects, respectively...
January 2018: Air Medical Journal
https://www.readbyqxmd.com/read/29332430/effect-of-creatine-phosphate-sodium-on-bispectral-index-and-recovery-quality-during-the-general-anaesthesia-emergence-period-in-elderly-patients-a-randomized-double-blind-placebo-controlled-trial
#4
Wei Wang, Wan-You Yu, Jie Lv, Lian-Hua Chen, Zhong Li
Objective To evaluate the effect of creatine phosphate sodium on bispectral index (BIS) and recovery quality during the general anaesthesia emergence period in elderly patients. Methods This randomized, double-blind, placebo-controlled study enrolled patients undergoing transabdominal cholecystectomy under general anaesthesia. Patients were randomly assigned to receive either creatine phosphate sodium (1.0 g/100 ml 0.9% saline; group P) or 100 ml 0.9% saline (group C) over 30 minutes during surgical incision...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29331966/effectiveness-and-safety-of-oral-sedation-in-adult-patients-undergoing-dental-procedures-protocol-for-a-systematic-review
#5
Jimmy de Oliveira Araújo, Rogério Heládio Lopes Motta, Cristiane de Cássia Bergamaschi, Caio Chaves Guimarães, Juliana Cama Ramacciato, Natalia Karol de Andrade, Mabel Fernandes Fiqueiró, Luciane Cruz Lopes
INTRODUCTION: The management of anxious patients undergoing dental procedures is still a challenge in clinical practice. Despite a wide variety of drugs for oral sedation in adult patients, there are relatively few systematic reviews that compare the effectiveness and safety of different drugs administered via this route. Thus, this study will evaluate the effectiveness and safety of oral sedation with benzodiazepines and other agents to patients undergoing dental surgical procedures...
January 13, 2018: BMJ Open
https://www.readbyqxmd.com/read/29331713/repeated-attempted-homicide-by-administration-of-drugs-documented-by-hair-analysis
#6
Valérie Baillif-Couniou, Christophe Bartoli, Caroline Sastre, Marjorie Chèze, Marc Deveaux, Georges Léonetti, Anne-Laure Pélissier-Alicot
Attempted murder by repeated poisoning is quite rare. The authors describe the case of a 62-year-old man who was admitted to an intensive care unit (ICU) for neurological disturbances complicated by inhalation pneumopathy. He presented a loss of consciousness while his wife was visiting him at the ICU (H0). Forty-eight hours later (H48), police officers apprehended the patient's wife pouring a liquid into his fruit salad at the hospital. Toxicological analyses of a blood sample and the infusion equipment (H0), as well as the fruit salad and its container (H48), confirmed the attempted poisoning with cyamemazine (H0) and hydrochloric acid (H48)...
January 5, 2018: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29331574/a-medicare-cost-analysis-of-mri-versus-ct-based-high-dose-rate-brachytherapy-of-the-cervix-can-mri-based-planning-be-less-costly
#7
Amishi Bajaj, Grant Harmon, John Weaver, Brendan Martin, Michael Mysz, Murat Surucu, John C Roeske, Andre A Konski, William Small, Matthew M Harkenrider
PURPOSE: While some institutions deliver multiple fractions per implant for MRI-based planning, it is common for only one fraction to be delivered per implant with CT-based cervical brachytherapy. The purpose of this study was to compare physician costs, hospital costs, and overall costs for cervical cancer patients treated with either CT-based or MRI-based high-dose-rate (HDR) cervical brachytherapy to determine if MRI-based brachytherapy as described can be financially feasible. METHODS AND MATERIALS: We identified 40 consecutive patients treated with curative intent cervical brachytherapy...
January 10, 2018: Brachytherapy
https://www.readbyqxmd.com/read/29331207/cerebral-amyloid-angiopathy-related-inflammation-a-case-report-presenting-diagnostic-difficulties
#8
Cecylia Rajczewska-Oleszkiewicz, Agnieszka Cyganek, Anna Stadnik, Dorota Dziewulska
We describe an 86-year-old woman with a history of hypertension who presented sudden disturbances of consciousness and left hemiparesis. Brain magnetic resonance imaging (MRI) revealed diffused hyperintensive changes on T2-weighted images localized subcortically in the white matter of both cerebral hemispheres, corresponding to acute vasogenic edema, causing moderate mass effect. Posterior reversible encephalopathy syndrome was initially diagnosed. After implementation of anti-edema intravenous steroid treatment and hypotensive therapy the symptoms began to retire, till the total regression...
January 6, 2018: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/29331168/dietary-patterns-and-their-associations-with-home-food-availability-among-finnish-pre-school-children-a-cross-sectional-study
#9
Henna Vepsäläinen, Liisa Korkalo, Vera Mikkilä, Reetta Lehto, Carola Ray, Kaija Nissinen, Essi Skaffari, Mikael Fogelholm, Leena Koivusilta, Eva Roos, Maijaliisa Erkkola
OBJECTIVE: To study the associations between home food availability and dietary patterns among pre-school children. DESIGN: Cross-sectional study in which parents of the participating children filled in an FFQ and reported how often they had certain foods in their homes. We derived dietary pattern scores using principal component analysis, and composite scores describing the availability of fruits and vegetables as well as sugar-enriched foods in the home were created for each participant...
January 14, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29330269/central-nervous-system-graft-versus-host-disease-cns-gvhd-after-allogeneic-haematopoietic-stem-cell-transplantation
#10
Karolina Polchlopek Blasiak, Federico Simonetta, Maria-Isabel Vargas, Yves Chalandon
A 60-year-old man presented with impaired consciousness and psychomotor agitation after a second allogeneic haematopoietic stem cell transplantation (HSCT) from a matched unrelated donor for acute myeloid leukaemia. Clinical, biological and radiological evidence suggested a diagnosis of central nervous system graft-versus-host disease (CNS-GvHD). After intrathecal infusion of methylprednisolone, the clinical symptoms as well as the radiological abnormalities disappeared. The present report illustrates the difficulties in the diagnosis and the management of CNS-GvHD, a very rare and still challenging neurological complication that can occur after allogeneic HSCT...
January 12, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29329968/reexamining-unconscious-response-priming-a-liminal-prime-paradigm
#11
Maayan Avneon, Dominique Lamy
Research on the limits of unconscious processing typically relies on the subliminal-prime paradigm. However, this paradigm is limited in the issues it can address. Here, we examined the implications of using the liminal-prime paradigm, which allows comparing unconscious and conscious priming with constant stimulation. We adapted an iconic demonstration of unconscious response priming to the liminal-prime paradigm. On the one hand, temporal attention allocated to the prime and its relevance to the task increased the magnitude of response priming...
January 9, 2018: Consciousness and Cognition
https://www.readbyqxmd.com/read/29329358/modulating-role-of-ang1-7-in-control-of-blood-pressure-and-renal-function-in-angii-infused-hypertensive-rats
#12
Marta Kuczeriszka, Elzbieta Kompanowska-Jezierska, Janusz Sadowski, Minolfa Prieto, L Gabriel Navar
Background: Indirect evidence suggests that angiotensin 1-7 (Ang1-7) may counterbalance prohypertensive actions of angiotensin II (AngII), via activation of vascular and/or renal tubular receptors to cause vasodilation and natriuresis/diuresis. We examined if Ang1-7 would attenuate the development of hypertension, renal vasoconstriction and decreased natriuresis in AngII-infused rats and evaluated the mechanisms involved. Methods: AngII, alone or with Ang1-7, was infused to conscious Sprague-Dawley rats for 13 days and systolic blood pressure (SBP) and renal excretion were repeatedly determined...
January 10, 2018: American Journal of Hypertension
https://www.readbyqxmd.com/read/29329247/a-simple-method-to-measure-renal-function-in-swine-by-the-plasma-clearance-of-iohexol
#13
Sergio Luis-Lima, Consolación García-Contreras, Marta Vázquez-Gómez, Susana Astiz, Fabiola Carrara, Flavio Gaspari, Natalia Negrín-Mena, Alejandro Jiménez-Sosa, Hugo Jiménez-Hernández, Antonio González-Bulnes, Esteban Porrini
There is no simple method to measure glomerular filtration rate (GFR) in swine, an established model for studying renal disease. We developed a protocol to measure GFR in conscious swine by using the plasma clearance of iohexol. We used two groups, test and validation, with eight animals each. Ten milliliters of iohexol (6.47 g) was injected into the marginal auricular vein and blood samples (3 mL) were collected from the orbital sinus at different points after injection. GFR was determined using two models: two-compartment (CL2: all samples) and one-compartment (CL1: the last six samples)...
January 12, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29328752/literature-review-awareness-of-anaesthesia
#14
Adam Smith
A review of qualitative literature regarding awareness under general anaesthesia was undertaken, this term being defined as full consciousness during surgery with explicit recall of events. This study was designed to explore perioperative practitioner knowledge, skill base and education on the subject of awareness. It also explores the practitioner role in, looking out for and rectification, their obligations to the patient and their statutory bodies, as well as adherence to standards of conduct, performance and ethics...
September 2017: Journal of Perioperative Practice
https://www.readbyqxmd.com/read/29328000/conscious-sedation-with-dexmedetomidine-compared-with-asleep-awake-asleep-craniotomies-in-glioma-surgery-an-analysis-of-180-patients
#15
Eric Suero Molina, Stephanie Schipmann, Isabelle Mueller, Johannes Wölfer, Christian Ewelt, Matthias Maas, Benjamin Brokinkel, Walter Stummer
OBJECTIVE Awake craniotomies have become a feasible tool over time to treat brain tumors located in eloquent regions. Different techniques have been applied in neurooncology centers. Both "asleep-awake-asleep" (asleep) and "conscious sedation" were used subsequently at the authors' neurosurgical department. Since 2013, the authors have only performed conscious sedation surgeries, predominantly using the α2-receptor agonist dexmedetomidine as the anesthetic drug. The aim of this study was to compare both mentioned techniques and evaluate the clinical use of dexmedetomidine in the setting of awake craniotomies for glioma surgery...
January 12, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29327782/development-of-manganese-enhanced-magnetic-resonance-imaging-of-the-rostral-ventrolateral-medulla-of-conscious-rats-importance-of-normalization-and-comparison-with-other-regions-of-interest
#16
Daniel J Huereca, Konstandinos A Bakoulas, Farhad Ghoddoussi, Bruce A Berkowitz, Avril Genene Holt, Patrick J Mueller
Spinally projecting neurons in the rostral ventrolateral medulla (RVLM) are believed to contribute to pathophysiological alterations in sympathetic nerve activity and the development of cardiovascular disease. The ability to identify changes in the activity of RVLM neurons in conscious animals and humans, especially longitudinally, would represent a clinically important advancement in our understanding of the contribution of the RVLM to cardiovascular disease. To this end, we describe the initial development of manganese-enhanced magnetic resonance imaging (MEMRI) for the rat RVLM...
January 12, 2018: NMR in Biomedicine
https://www.readbyqxmd.com/read/29327721/midazolam-use-for-dental-conscious-sedation-how-safe-are-we
#17
Z Shehabi, C Flood, L Matthew
No abstract text is available yet for this article.
January 12, 2018: British Dental Journal
https://www.readbyqxmd.com/read/29327682/analysis-of-implementiation-of-4th-head-and-neck-cancer-awareness-week-in-department-of-otolaryngology-in-mi%C3%A4-dzyleski-hospital-in-warsaw
#18
Karolina Dżaman, Karolina Piskadło-Zborowska, Mirosława Pietniczka-Załęska
INTRODUCTION: The aim of the study was to analyze the profile of patients applying for free preventive examinations within The Forth European Head an Neck Cancer (HNC) Awareness Week in the Department of Otorhynolaryngology in Międzyleski Hospital in Warsaw (ORL MSS). MATERIAL AND METHODS: A media campaign was designed to inform HNC risk patients about the opportunity to receive free preventive examinations in ORL MSS. 225 patients were enrolled to the study. Patient age ranged from 26 to 92 (average 63 years)...
August 31, 2017: Otolaryngologia Polska
https://www.readbyqxmd.com/read/29327348/respiratory-dysfunction-progresses-with-age-in-kcna1-null-mice-a-model-of-sudden-unexpected-death-in-epilepsy
#19
Kristina A Simeone, Jodi Hallgren, Charles S Bockman, Ankita Aggarwal, Vikash Kansal, Lauren Netzel, Shruthi H Iyer, Stephanie A Matthews, Malavika Deodhar, Peter J Oldenburg, Peter W Abel, Timothy A Simeone
OBJECTIVE: Increased breathing rate, apnea, and respiratory failure are associated with sudden unexpected death in epilepsy (SUDEP). We recently demonstrated the progressive nature of epilepsy and mortality in Kcna1-/- mice, a model of temporal lobe epilepsy and SUDEP. Here we tested the hypothesis that respiratory dysfunction progresses with age in Kcna1-/- mice, thereby increasing risk of respiratory failure and sudden death (SD). METHODS: Respiratory parameters were determined in conscious mice at baseline and following increasing doses of methacholine (MCh) using noninvasive airway mechanics (NAM) systems...
January 12, 2018: Epilepsia
https://www.readbyqxmd.com/read/29327337/generalized-nonmotor-absence-seizures-what-do-absence-generalized-and-nonmotor-mean
#20
REVIEW
Iris Unterberger, Eugen Trinka, Peter W Kaplan, Gerald Walser, Gerhard Luef, Gerhard Bauer
OBJECTIVE: Clinical absences are now classified as "generalized nonmotor (absence) seizures" by the International League Against Epilepsy (ILAE). The aim of this paper is to critically review the concept of absences and to put the accompanying focal and motor symptoms into the context of the emerging pathophysiological knowledge. METHODS: For this narrative review we performed an extensive literature search on the term "absence," and analyzed the plethora of symptoms observed in clinical absences...
January 11, 2018: Epilepsia
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