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Maria Rosa Costanzo, Daniel Negoianu, Brian E Jaski, Bradley A Bart, James T Heywood, Inder S Anand, James M Smelser, Alan M Kaneshige, Don B Chomsky, Eric D Adler, Garrie J Haas, James A Watts, Jose L Nabut, Michael P Schollmeyer, Gregg C Fonarow
OBJECTIVES: The AVOID-HF (Aquapheresis versus Intravenous Diuretics and Hospitalization for Heart Failure) trial tested the hypothesis that patients hospitalized for HF treated with adjustable ultrafiltration (AUF) would have a longer time to first HF event within 90 days after hospital discharge than those receiving adjustable intravenous loop diuretics (ALD). BACKGROUND: Congestion in hospitalized heart failure (HF) patients portends unfavorable outcomes. METHODS: The AVOID-HF trial, designed as a multicenter, 1-to-1 randomized study of 810 hospitalized HF patients, was terminated unilaterally and prematurely by the sponsor (Baxter Healthcare, Deerfield, Illinois) after enrollment of 224 patients (27...
February 2016: JACC. Heart Failure
Maria Rosa Costanzo, Daniel Negoianu, Gregg C Fonarow, Brian E Jaski, Bradley A Bart, J Thomas Heywood, Jose L Nabut, Michael P Schollmeyer
BACKGROUND: In patients hospitalized with acutely decompensated heart failure, unresolved signs and symptoms of fluid overload have been consistently associated with poor outcomes. Regardless of dosing and type of administration, intravenous loop diuretics have not reduced heart failure events or mortality in patients with acutely decompensated heart failure. The results of trials comparing intravenous loop diuretics to mechanical fluid removal by isolated venovenous ultrafiltration have yielded conflicting results...
September 2015: American Heart Journal
Patricia Armand, David Boutarin, Raphaëlle Gerbaaï
Used in France for the last two years, aquapheresis is a technique to remove excess water from patients with heart failure resistant to diuretics. The therapy is delivered during the patient's hospitalisation in a cardiology intensive care unit to ensure optimal monitoring and the prevention of potential complications. A team from Grenoble shares its experience.
March 2015: Revue de L'infirmière
C Urso, S Brucculeri, G Caimi
WHAT IS KNOWN AND OBJECTIVE: Hyponatraemia, the most common electrolyte imbalance occurring in hospitalized subjects, is usually classified as hypovolaemic, euvolaemic or hypervolaemic. Hyponatraemia is a predictor of death among subjects with chronic heart failure and cirrhosis. The inappropriate secretion of the antidiuretic hormone (AVP) seems to be of pivotal importance in the decline of serum sodium concentration in these clinical conditions. The objective of this review was to summarize recent progress in management of hyponatraemia in SIADH, cirrhosis and heart failure...
August 2015: Journal of Clinical Pharmacy and Therapeutics
Xenia Sumin, Maria V Devita
No abstract text is available yet for this article.
December 2014: American Surgeon
Melissa Peterangelo
Ultrafiltration has been utilized for volume removal for over 50 years. Recent technology advances have allowed for a simplified approach to the traditional treatment. This article focuses on the practical aspects of incorporating the newer Aquapheresis therapy into a hospital setting and the outcomes.
2008: Progress in Cardiovascular Nursing
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