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Halie J Martin, B Tyler White, Christopher J Scanlon, Tomonori Saito, Mark D Dadmun
With a growing variety of nanoparticles available, research probing the influence of particle deformability, morphology, and topology on the behavior of all polymer nanocomposites is also increasing. In particular, the behavior of soft polymeric nanoparticles in polymer nanocomposites has displayed unique behavior, but their precise performance depends intimately on the internal structure and morphology of the nanoparticle. With the goal of providing guidelines to control the structure and morphology of soft polymeric nanoparticles, we have examined monomer starved semi-batch nano-emulsion polymerizations that form organic, soft nanoparticles, to correlate the precise structure of the nanoparticle to the rate of monomer addition and crosslinking density...
November 16, 2017: Soft Matter
Ray Marin, Diego Cortez, Francesco Lamanna, Madapura M Pradeepa, Evgeny Leushkin, Philippe Julien, Angélica Liechti, Jean Halbert, Thoomke Brüning, Katharina Mössinger, Timo Trefzer, Christian Conrad, Halie N Kerver, Juli Wade, Patrick Tschopp, Henrik Kaessmann
Sex chromosomes differentiated from different ancestral autosomes in various vertebrate lineages. Here, we trace the functional evolution of the XY Chromosomes of the green anole lizard (Anolis carolinensis), on the basis of extensive high-throughput genome, transcriptome and histone modification sequencing data and revisit dosage compensation evolution in representative mammals and birds with substantial new expression data. Our analyses show that Anolis sex chromosomes represent an ancient XY system that originated at least ≈160 million years ago in the ancestor of Iguania lizards, shortly after the separation from the snake lineage...
November 13, 2017: Genome Research
Hayretdin Koklu, Tuğrul Pürnak, Nomingerel Tseveldorj, Ege Altan, Halis Şimşek
No abstract text is available yet for this article.
November 1, 2017: Annals of Pharmacotherapy
Jesús R Lara, Matthew T Kamiyama, Gabriel Hernandez, Justin Nay, Mark S Hoddle, Yulin Gao
In the United States, California (CA) is the primary commercial producer of pistachio nuts, Pistacia vera L. (Anacardiaceae). The brown marmorated stink bug (BMSB), Halyomorpha halys (Stål) (Hemiptera: Pentatomidae), an invasive and polyphagous insect pest from Asia, has established in urban areas in several pistachio-growing counties in CA. Breeding BMSB populations have not been detected in commercial pistachio acreage. However, the detection of BMSB in Kern and Fresno counties, major Kerman pistachio producing areas in CA, underscored key knowledge gaps on BMSB ecology in CA and motivated investigations on the susceptibility of pistachio nuts to BMSB feeding...
September 1, 2017: Journal of Insect Science
Sarit Polsky, Halis K Akturk
PURPOSE OF REVIEW: The purpose of the study is to examine and summarize studies reporting on the epidemiology, the risk of developing diabetes, and the cardiovascular effects on individuals with diabetes of different levels of alcohol consumption. RECENT FINDINGS: Men consume more alcohol than women in populations with and without diabetes. Light-to-moderate alcohol consumption decreases the incidence of diabetes in the majority of the studies, whereas heavy drinkers and binge drinkers are at increased risk for diabetes...
November 4, 2017: Current Diabetes Reports
Sabriye Korkut, Şeyma Memur, Hülya Halis, Osman Bastuğ, Levent Korkmaz, Ahmet Özdemir, Tamer Güneş, Mehmet Adnan Öztürk, Selim Kurtoğlu
OBJECTIVE: Cystatin C (CysC) is commonly used as a marker of renal failure. The aim of this study was to investigate serum CysC levels in osteopenia of prematurity (OP) and determine whether CysC could be safely used as a marker of renal insufficiency in infants with OP. METHODS: The study included 50 preterm infants (≤ 32 gestational weeks). Calcium (Ca), phosphorous (P), and alkaline phosphatase (ALP) serum levels were measured in postnatal week 9, and bone density was measured concurrently by quantitative ultrasonography...
October 30, 2017: Journal of Clinical Research in Pediatric Endocrinology
Mansoor Syed, Pragnya Das, Aishwarya Pawar, Zubair H Aghai, Anu Kaskinen, Zhen W Zhuang, Namasivayam Ambalavanan, Gloria Pryhuber, Sture Andersson, Vineet Bhandari
Hyperoxia-induced acute lung injury (HALI) is a key contributor to the pathogenesis of bronchopulmonary dysplasia (BPD) in neonates, for which no specific preventive or therapeutic agent is available. Here we show that lung micro-RNA (miR)-34a levels are significantly increased in lungs of neonatal mice exposed to hyperoxia. Deletion or inhibition of miR-34a improves the pulmonary phenotype and BPD-associated pulmonary arterial hypertension (PAH) in BPD mouse models, which, conversely, is worsened by miR-34a overexpression...
October 27, 2017: Nature Communications
Yong Lu, Mengyao Chen, Katie Reding, Leslie Pick
Hemiptera is a large clade of insects understudied in terms of developmental biology. Halyomorpha halys, the Brown Marmorated Stink Bug (BMSB, referred to throughout as H. halys), is an invasive hemipteran pest of the mid-Atlantic region of the USA that has rapidly spread to other regions in recent years, devastating a wide range of crops using a piercing and sucking mechanism. Its phylogenetic position, polyphagous habits, and rapid spread in the USA suggested that H. halys would be an ideal system to broaden our knowledge of developmental mechanisms in insects...
2017: EvoDevo
Halis Kaan Akturk Md, Seda Yasa MSc
Wolfram syndrome (WFS) is a rare autosomal recessive disease with non-autoimmune childhood onset insulin dependent diabetes and optic atrophy. WFS type 2 (WFS2) differs from WFS type 1 (WFS1) with upper intestinal ulcers, bleeding tendency and the lack ofdiabetes insipidus. Li-fespan is short due to related comorbidities. Only a few familieshave been reported with this syndrome with the CISD2 mutation. Here we report two siblings with a clinical diagnosis of WFS2, previously misdiagnosed with type 1 diabetes mellitus and diabetic retinopathy-related blindness...
2017: Pediatric Endocrinology, Diabetes, and Metabolism
Erica Jean Kistner
The invasive brown marmorated stink bug, Halyomorpha halys (Stål; Hemiptera: Pentatomidae), has recently emerged as a harmful pest of horticultural crops in North America and Europe. Native to East Asia, this highly polyphagous insect is spreading rapidly worldwide. Climate change will add further complications to managing this species in terms of both geographic distribution and population growth. This study used CLIMEX to compare potential H. halys distribution under recent and future climate models using one emission scenario (A2) with two different global circulation models, CSIRO Mk3...
October 23, 2017: Environmental Entomology
Tracy C Leskey, Anne L Nielsen
The brown marmorated stink bug (BMSB), Halyomorpha halys (Stål), is an invasive pentatomid introduced from Asia into the United States, Canada, multiple European countries, and Chile. In 2010, BMSB populations in the mid-Atlantic United States reached outbreak levels and subsequent feeding severely damaged tree fruit as well as other crops. Significant nuisance issues from adults overwintering inside homes were common. BMSB is a highly polyphagous species with a strong dispersal capacity and high reproductive output, potentially enabling its spread and success in invaded regions...
October 25, 2017: Annual Review of Entomology
Halis Boran, Savaş Şaffak
With the use of nanoparticles (NPs) in many industrial activities and consumer products, it is important to evaluate the effects of their release into the environment. Metal NPs (e.g., Ni-NPs or Cu-NPs) can release metal ions that are toxic to aquatic organisms; however, whether the toxicity is from metal ions rather than unique "nano-scale" effects of the NPs is unresolved. This research investigated Ni-NP toxicity in zebrafish Danio rerio larvae to clarify whether toxic effects are attributable to release of Ni ions...
October 22, 2017: Archives of Environmental Contamination and Toxicology
Vicki Brown, Marj Moodie, Linda Cobiac, Herrera Mantilla, Robert Carter
OBJECTIVE: To review Australian policies on active transport, defined as walking and cycling for utilitarian purposes. To estimate the potential health impact of achieving four active transport policy scenarios. METHODS: A policy review was undertaken, using key words to search government websites. Potential health benefits were quantified using a cohort simulation Markov model to estimate obesity and transport injury-related health effects of an increase in active transport...
October 18, 2017: Australian and New Zealand Journal of Public Health
Hakan Kalaycı, Ebru Tarım, Halis Özdemir, Tayfun Çok, Ayşe Parlakgümüş
Corpus callosum agenesis (CCA) is a clinical condition accompanied by various aneuploidy and genetic syndromes. We identified the development of the corpus callosum (CC) in 278 patients before 18 weeks of gestational age by visualising the pericallosal artery (PCA) in the callosal sulcus and changes in the lengths and ratios of the midbrain (MB) and falx (F), which suggested elevation of the third ventricle and thalamus due to CCA in the first trimester. We succeeded in visualising the path of the PCA in 273 patients...
October 10, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
Ann E Hajek, Leellen F Solter, Joseph V Maddox, Wei-Fone Huang, Alden S Estep, Grzegorz Krawczyk, Donald C Weber, Kim A Hoelmer, Neil D Sanscrainte, James J Becnel
We describe a unique microsporidian species that infects the green stink bug, Chinavia hilaris, the brown marmorated stink bug, Halyomorpha halys, the brown stink bug, Euschistus servus, and the dusky stink bug, Euschistus tristigmus. All life stages are unikaryotic, but analysis of the consensus small subunit region of the ribosomal gene places this microsporidium in the genus Nosema, which historically has been characterized by diplokaryotic life stages. It is also characterized by having the reversed arrangement of the ribosomal gene (LSU -ITS- SSU) found in species within the "true Nosema" clade...
October 6, 2017: Journal of Eukaryotic Microbiology
T J Welsh, L D Stringer, R Caldwell, J E Carpenter, D M Suckling
PURPOSE: Brown marmorated stink bugs, Halyomorpha halys Stål (Hemiptera: Pentatomidae), are regularly intercepted, but there are few eradication tools. Currently, no sterile insect technique program exists for Hemiptera. MATERIALS AND METHODS: Adult males were irradiated at 4-60 Gy, mated and their progeny reared for two generations, with mortality assessed at F1 egg, F1 adult and F2 egg stages. RESULTS: The F1 eggs showed a dose response to irradiation between 4 and 36 Gy, with 97% sterility at 16 Gy, and higher doses producing complete egg mortality...
November 2, 2017: International Journal of Radiation Biology
Halis Sonmez, Varinder Kambo, Dimiter Avtanski, Larry Lutsky, Leonid Poretsky
OBJECTIVE: We examined the 30-day hospital readmission rates and their association with the admission diagnosis and the length of stay (LOS) in patients with diabetes versus those without diabetes mellitus (DM) in an urban teaching hospital. METHODS: In this retrospective study, we compared the 30-day readmission rates in patients with DM (n=16,266) versus those without DM (n=86,428) at an urban teaching hospital between January 1, 2013, and September 30, 2015. In individuals with a secondary diagnosis of DM, we analyzed the relationship between readmission rates and the ten most common Medicare Severity Diagnosis Related Groups (MS-DRGs)...
July 19, 2017: Journal of Diabetes and its Complications
Simone M Nicholson, Gianluca Carlesso, Lily I Cheng, Halie Cook, Karma DaCosta, Joel Leininger, Kathleen McKeever, Stephen Weasel Scott, Devon Taylor, Katie Streicher, Steve Eck, Molly Reed, Raffaella Faggioni, Ronald Herbst, Rakesh Dixit, Patricia C Ryan
MEDI-570 is a fully human afucosylated monoclonal antibody (MAb) against Inducible T-cell costimulator (ICOS), highly expressed on CD4+ T follicular helper (TFH) cells. Effects of MEDI-570 were evaluated in an enhanced pre-postnatal development toxicity (ePPND) study in cynomolgus monkeys. Administration to pregnant monkeys did not cause any abortifacient effects. Changes in hematology and peripheral blood T lymphocyte subsets in maternal animals and infants and the attenuated infant IgG immune response to keyhole limpet hemocyanin (KLH) were attributed to MEDI-570 pharmacology...
September 13, 2017: Reproductive Toxicology
Pınar Çağlar Aytaç, Bülent Haydardedeoğlu, Halis Özdemir, Esra Bulgan Kılıçdağ
OBJECTIVE: To evaluate the effects of a gonadotropin releasing hormone agonist (GnRHa) injection prior to embryo transfer on implantation and pregnancy rate. MATERIALS AND METHODS: We performed a retrospective analysis of patients undergoing in vitro fertilization (IVF) therapy with and without GnRHa preinstallation into the uterine cavity just before embryo transfer between January 2012 and March 2013 in a single IVF center of a university hospital. Patients were evaluated based upon implantation, pregnancy, live birth, and miscarriage rates...
June 2017: Turk J Obstet Gynecol
Anne L Nielsen, Shelby Fleischer, George C Hamilton, Tori Hancock, Gregorz Krawczyk, Jana C Lee, Emily Ogburn, John M Pote, Amy Raudenbush, Ann Rucker, Michael Saunders, Victoria P Skillman, Jeanne Sullivan, Jody Timer, James Walgenbach, Nik G Wiman, Tracy C Leskey
Temperature-based degree-day models describe insect seasonality and to predict key phenological events. We expand on the use of a temperature-based process defining timing of reproduction through the incorporation of female reproductive physiology for the invasive pentatomid species Halyomorpha halys, the brown marmorated stink bug. A five-stage ranking system based on ovary development was able to distinguish between the reproductive statuses of field-collected females. Application of this ranking method described aspects of H...
September 2017: Ecology and Evolution
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