Read by QxMD icon Read


Purushottam R Lomate, Bryony C Bonning
Management of the brown marmorated stink bug, Halyomorpha halys (Hemiptera: Pentatomidae), an invasive, agricultural pest in the United States, has presented significant challenges. This polyphagous insect uses both extra-oral and gut-based digestion thwarting protein- or nucleotide-based control strategies. The objective of this study was to biochemically characterize the digestive enzymes (proteases and nucleases) from the saliva, salivary gland and the gut of H. halys. Enzyme profiles for the two tissues and saliva radically differ: The pH optimum for proteases in the gut was six, with cysteine proteases predominant...
March 12, 2018: Archives of Insect Biochemistry and Physiology
Leah Schwiesow, Erin Mettert, Yahan Wei, Halie K Miller, Natalia G Herrera, David Balderas, Patricia J Kiley, Victoria Auerbuch
Despite the mammalian host actively sequestering iron to limit pathogenicity, heme (or hemin when oxidized) and hemoproteins serve as important sources of iron for many bloodborne pathogens. The HmuRSTUV hemin uptake system allows Yersinia species to uptake and utilize hemin and hemoproteins as iron sources. HmuR is a TonB-dependent outer membrane receptor for hemin and hemoproteins. HmuTUV comprise a inner membrane ABC transporter that transports hemin and hemoproteins from the periplasmic space into the bacterial cytoplasm, where it is degraded by HmuS...
2018: Frontiers in Cellular and Infection Microbiology
Paul S Botch, Ernest S Delfosse
Trissolcus japonicus (Ashmead) (Hymenoptera: Scelionidae) is an egg parasitoid wasp from East Asia. It is considered to be an important natural enemy of the brown marmorated stink bug, Halyomorpha halys (Stål) (Hemiptera: Pentatomidae). Ongoing efforts to evaluate the physiological host range of this potential classical biological control agent have demonstrated that the wasp can parasitize at least 11 genera of nontarget Pentatomoidea in North America in no-choice tests. However, factors such as host-acceptance behavior that might affect nontarget parasitism in the field are poorly understood...
March 1, 2018: Environmental Entomology
Ziyaattin Karakuzu, Remzi Iscimen, Halis Akalin, Nermin Kelebek Girgin, Ferda Kahveci, Melda Sinirtas
BACKGROUND Ventilator-associated pneumonia (VAP) is a nosocomial infection commonly seen in patients in intensive care units (ICU). This study aimed to analyze factors affecting prognosis of patients diagnosed with VAP. MATERIAL AND METHODS Critically ill patients with VAP were retrospectively evaluated between June 2002 and June 2011 in the ICU. VAP diagnosis was made according to 2005 ATS/IDSA (Infectious Diseases Society of America/American Thoracic Society) criteria. First pneumonia attacks of patients were analyzed...
March 5, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Halis Kaan Akturk, Ana Maria Chindris, Jolaine M Hines, Ravinder J Singh, Victor J Bernet
OBJECTIVE: To assess whether dietary supplements that are herbal and/or animal-derived products, marketed for enhancing metabolism or promoting energy, "adrenal fatigue," or "adrenal support," contain thyroid or steroid hormones. METHODS: Twelve dietary adrenal support supplements were purchased. Pregnenolone, androstenedione, 17-hydroxyprogesterone, cortisol, cortisone, dehydroepiandrosterone sulfate, synthetic glucocorticoids (betamethasone, dexamethasone, fludrocortisone, megestrol acetate, methylprednisolone, prednisolone, prednisone, budesonide, and triamcinolone acetonide) levels were measured twice in samples in a blinded fashion...
March 2018: Mayo Clinic Proceedings
Antonela Muca, Emily Standafer, Aaron K Apawu, Farhan Ahmad, Farhad Ghoddoussi, Mirabela Hali, James Warila, Bruce A Berkowitz, Avril Genene Holt
Loud noise frequently results in hyperacusis or hearing loss (i.e., increased or decreased sensitivity to sound). These conditions are often accompanied by tinnitus (ringing in the ears) and changes in spontaneous neuronal activity (SNA). The ability to differentiate the contributions of hyperacusis and hearing loss to neural correlates of tinnitus has yet to be achieved. Towards this purpose, we used a combination of behavior, electrophysiology, and imaging tools to investigate two models of noise-induced tinnitus (either with temporary hearing loss or with permanent hearing loss)...
February 27, 2018: Brain Structure & Function
Yufeng Zhang, Adam L Brasher, Noel R Park, Halie A Taylor, Andreas N Kavazis, Wendy R Hood
Understanding of physiological responses of organisms is typically based on data collected during an isolated event. Although many fundamental insights have been gained from these studies, evaluating the response to a single event ignores the fact that each individual has experienced a unique set of events throughout its life that may have altered its physiology. The idea that prior experiences can influence subsequent performance is known as a carry-over effect. Carry-over effects may explain much of the variation in performance found among individuals...
February 27, 2018: Journal of Experimental Biology
Joe M Kaser, Anne L Nielsen, Paul K Abram
As the rate of spread of invasive species increases, consumer-resource communities are often populated by a combination of exotic and native species at all trophic levels. In parasitoid-host communities, these novel associations may lead to disconnects between parasitoid preference and performance, and parasitoid oviposition may result in death of the parasitoid offspring, death of the host, or death of both. Despite their relevance for biological control risk and efficacy assessments, the direct and indirect population-level consequences of parasitoids attacking and killing their hosts without successfully reproducing (non-reproductive mortality) are poorly understood...
February 27, 2018: Ecological Applications: a Publication of the Ecological Society of America
Michael F Nyp, Sherry M Mabry, Angels Navarro, Heather Menden, Ricardo E Perez, Venkatesh Sampath, Ikechukwu I Ekekezie
The onset and degree of injury occurring in animals that develop hyperoxic acute lung injury (HALI) is dependent on age at exposure, suggesting that developmentally regulated pathways/factors must underlie initiation of the epithelial injury and subsequent repair. Type II TGFβ receptor interacting protein-1 (TRIP-1) is a negative regulator of TGFβ signaling, which we have previously shown is a developmentally regulated protein with modulatory effects on epithelial-fibroblastic signaling. The aim of this study was to assess if type II alveolar epithelial cells overexpressing TRIP-1 are protected against hyperoxia-induced epithelial injury, and in turn HALI...
March 2018: Physiological Reports
Ahmet Afşin Oktay, Halis Kaan Akturk, Kerim Esenboğa, Fahad Javed, Nichole M Polin, Eiman Jahangir
Diabetes mellitus (DM) has become a public health problem worldwide, and it has large implications for cardiovascular disease (CVD). In this article, we discuss the etiology and pathophysiology of CVD in DM including the effects of abnormal glucose homeostasis, genetic factors, epigenetics, apoptosis, common pathophysiological mechanisms shared by both DM and CVD, and contributions of other comorbidities. We then cover the pathogenesis of both atherosclerotic disease and cardiomyopathy in relation to DM. Finally, we discuss the prevention of heart disease in DM with a focus on hypertension and dyslipidemia management, weight loss, lifestyle changes, antiplatelet therapy, and glycemic control...
March 2018: Current Problems in Cardiology
Nurdan Gamze Taşlı, Turgay Uçak, Yücel Karakurt, Ferda Keskin Çimen, Aslı Özbek Bilgin, Nezahat Kurt, Halis Süleyman
AIM: To determine the role of rutin in prevention of cisplatin induced retinal and optic nerve injury in an experimental study. MATERIAL AND METHODS: Totally 18 albino Wistar male rats were assigned into 3 groups, as follows: healthy controls (HC group), only cisplatin administered group for 14 days (CIS group), and Rutin + cisplatin administered group for 14 days (RC group). Blood samples were obtained from animals just before the scarification. Serum malondialdehyde (MDA), Myeloperoxidase (MPO), total glutathione (tGSH), Superoxide Dismutase (SOD), interleukin 1 beta (IL-1β) and tumor necrosis factor alpha (TNF-α) levels were investigated...
February 19, 2018: Cutaneous and Ocular Toxicology
Song Qin, Miao Chen, Hui Ji, Guo-Yue Liu, Hong Mei, Kang Li, Tao Chen
Hyperoxia‑induced acute lung injury (HALI) as one of the most common complications in patents on mechanical ventilation, and there are no efficient methods to overcome this at present. It was hypothesized that microRNA 21‑5p(miR‑21‑5p) can promote the survival of type II alveolar epithelial cells (AECII), alleviating HALI. The present study aimed to combine gene chip analysis with the overexpression miR‑21‑5p to develop a novel therapeutic option for HALI. It was found that AECII apoptosis was an important pathogenic event in the development of HALI, and the overexpression of miR‑21‑5p prevented HALI, associated with reducing AECII apoptosis...
February 6, 2018: Molecular Medicine Reports
Alejandro Otero-Bravo, Shana Goffredi, Zakee L Sabree
Phytophagous stink bugs are globally-distributed and many harbor vertically-inherited bacterial symbionts that are extracellular, yet little is known about how the symbiont's genomes have evolved under this transmission strategy. Genome reduction is common in insect intracellular symbionts but limited genome sampling of the extracellular symbionts of distantly-related stink bugs has precluded inferring patterns of extracellular symbiont genome evolution. To address this knowledge gap, we completely sequenced the genomes of the uncultivable bacterial symbionts of four neotropical stink bugs of the Edessa genus...
February 6, 2018: Genome Biology and Evolution
Chuck A Ingels, Kent M Daane
The brown marmorated stink bug, Halyomorpha halys (Stål) (Hemiptera: Pentatomidae), is an invasive pest that has been resident in California since 2006. To better understand its seasonal phenology, we used baited traps to estimate nymph and adult population densities in midtown Sacramento, the focal area of the Northern California invasion. Adult H. halys populations were found soon after trapping began in February (2015-2016) or March (2014); the first egg masses for 2014, 2015, and 2016 were found on 5 May, 17 April, and 12 April, respectively, and the first nymphs were found 3 June, 19 May, and 9 May, respectively...
January 30, 2018: Journal of Economic Entomology
Hali Morrison, Geetha Menon, Matthew P Larocque, Bob van Veelen, Yury Niatsetski, Ezekiel Weis, Ron S Sloboda
PURPOSE: To investigate the dose calculation accuracy in water medium of the Advanced Collapsed cone Engine (ACE) for three sizes of COMS eye plaques loaded with low-energy I-125 seeds. METHODS: A model of the Oncura 6711 I-125 seed was created for use with ACE in Oncentra® Brachy (OcB) using primary-scatter separated (PSS) point dose kernel and Task Group (TG) 43 datasets. COMS eye plaque models of diameters 12, 16, and 20 mm were introduced into the OcB applicator library based on 3D CAD drawings of the plaques and Silastic inserts...
January 31, 2018: Medical Physics
Raman Bansal, Andy Michel
BACKGROUND: The brown marmorated stink bug (Halyomorpha halys) is an invasive pest in North America which causes severe economic losses on tree fruits, ornamentals, vegetables, and field crops. The H. halys is an extreme generalist and this feeding behaviour may have been a major contributor behind its establishment and successful adaptation in invasive habitats of North America. To develop an understanding into the mechanism of H. halys' generalist herbivory, here we specifically focused on genes putatively facilitating its adaptation on diverse host plants...
January 18, 2018: BMC Genomics
Laura J Nixon, William R Morrison, Kevin B Rice, Eckehard G Brockerhoff, Tracy C Leskey, Filadelfo Guzman, Ashot Khrimian, Stephen Goldson, Michael Rostás
The brown marmorated stink bug, Halyomorpha halys, is an agricultural and urban pest that has become widely established as an invasive species of major concern in the USA and across Europe. This species forms large aggregations when entering diapause, and it is often these aggregations that are found by officials conducting inspections of internationally shipped freight. Identifying the presence of diapausing aggregations of H. halys using their emissions of volatile organic compounds (VOCs) may be a potential means for detecting and intercepting them during international freight inspections...
2018: PloS One
Zheng Wei, Wenjing Jiang, Hengzhen Wang, Hali Li, Bo Tang, Bing Liu, Hongchi Jiang, Xueying Sun
Thromboangiitis obliterans (TAO) (also known as Buerger's disease) is an inflammatory vascular disease that predominantly affects small- and medium-sized blood vessels of extremities. Endothelial cells play critical roles in the initiation and progression of this disease, but the underlying mechanisms remain unclear. In the present study, we demonstrate that patients with TAO had significantly higher levels of interleukin-6 (IL-6), soluble intercellular adhesion molecule-1 (sICAM-1) and soluble vascular cell adhesion molecule-1 (sVCAM-1) in their plasmas, and the involved arterial tissues expressed higher levels of phosphorylated signal transducer and activator of transcription 3 (p-STAT3), ICAM-1 and VCAM-1...
January 12, 2018: Cellular Signalling
Didem Onk, Renad Mammadov, Bahadir Suleyman, Ferda Keskin Cimen, Murat Cankaya, Vahdet Gul, Durdu Altuner, Onur Senol, Yucel Kadioglu, Ismail Malkoc, Halis Suleyman
Thiamine pyrophosphate (TPP) is the active metabolite of thiamine. This study aimed to investigate the effects of thiamine and TPP on cisplatin-induced peripheral neuropathic pain (PNP). Male albino Wistar type Rattus norvegicus were divided into six groups (n=6) that received 2 mg/kg cisplatin (CIS), 25 mg/kg thiamine (TM), 2 mg/kg cisplatin+25 mg/kg thiamine (CTM), 25 mg/kg TPP (TPP), 2 mg/kg cisplatin+25 mg/kg TPP (CTPP), or distilled water (healthy group; HG) for 8 days intraperitoneally. Analgesic effect was measured with a Basile Algesimeter...
January 12, 2018: Experimental Animals
Michael E Donaldson, Yessica Rico, Karsten Hueffer, Halie M Rando, Anna V Kukekova, Christopher J Kyle
Pathogens are recognized as major drivers of local adaptation in wildlife systems. By determining which gene variants are favored in local interactions among populations with and without disease, spatially explicit adaptive responses to pathogens can be elucidated. Much of our current understanding of host responses to disease comes from a small number of genes associated with an immune response. High-throughput sequencing (HTS) technologies, such as genotype-by-sequencing (GBS), facilitate expanded explorations of genomic variation among populations...
January 2018: Ecology and Evolution
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"