Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#21
JOURNAL ARTICLE
Xingzheng Liu, Jinying Mo, Xuerui Yang, Ling Peng, Youjia Zeng, Yihou Zheng, Gaofeng Song
BACKGROUND: Observational studies and some experimental investigations have indicated that gut microbiota are closely associated with the incidence and progression of chronic renal failure. However, the causal relationship between gut microbiota and chronic renal failure remains unclear. The present study employs a two-sample Mendelian randomization approach to infer the causal relationship between gut microbiota and chronic renal failure at the genetic level. This research aims to determine whether there is a causal effect of gut microbiota on the risk of chronic renal failure, aiming to provide new evidence to support targeted gut therapy for the treatment of chronic renal failure...
2024: Frontiers in Microbiology
#22
JOURNAL ARTICLE
Benedikt N Beer, Caroline Kellner, Jonas Sundermeyer, Lisa Besch, Angela Dettling, Paulus Kirchhof, Stefan Blankenberg, Christina Magnussen, Benedikt Schrage
AIMS: Acute heart failure (AHF) can result in worsening of heart failure (WHF), cardiogenic shock (CS), or death. Risk factors for these adverse outcomes are not well characterized. This study aimed to identify predictors for WHF or new-onset CS in patients hospitalized for AHF. METHODS AND RESULTS: Prospective cohort study enrolling consecutive patients with AHF admitted to a large tertiary care centre with follow-up until death or discharge. WHF was defined by the RELAX-AHF-2 criteria...
April 17, 2024: ESC Heart Failure
#23
JOURNAL ARTICLE
Ana Raquel Claro, Ana Rita Oliveira, Filipa Durão, Patrícia Costa Reis, Ana Rita Sandes, Carla Pereira, José Esteves da Silva
OBJECTIVES: Growth failure is one of the major complications of pediatric chronic kidney disease. Even after a kidney transplant (KT), up to 50 % of patients fail to achieve the expected final height. This study aimed to assess longitudinal growth after KT and identify factors influencing it. METHODS: A retrospective observational study was performed. We reviewed the clinical records of all patients who underwent KT for 25 years in a single center (n=149) and performed telephone interviews...
April 18, 2024: Journal of Pediatric Endocrinology & Metabolism: JPEM
#24
JOURNAL ARTICLE
Rahul Aggarwal, Deepak L Bhatt, Michael Szarek, Lawrence A Leiter, Christopher P Cannon, Renato D Lopes, Michael J Davies, Phillip Banks, Bertram Pitt, Ph Gabriel Steg
No abstract text is available yet for this article.
April 17, 2024: European Journal of Heart Failure
#25
JOURNAL ARTICLE
José-Manuel Ramos-Rincón, Héctor Pinargote-Celorio, Pilar González-de-la-Aleja, José Sánchez-Payá, Sergio Reus, Juan-Carlos Rodríguez-Díaz, Esperanza Merino
BACKGROUND: Estimating the global influenza burden in terms of hospitalization and death is important for optimizing prevention policies. Identifying risk factors for mortality allows for the design of strategies tailored to groups at the highest risk. This study aims to (a) describe the clinical characteristics of hospitalizations with a diagnosis of influenza over five flu seasons (2016-2017 to 2020-2021), (b) assess the associated morbidity (hospitalization rates and ICU admissions rate), mortality and cost of influenza hospitalizations in different age groups and (c) analyze the risk factors for mortality...
2024: Frontiers in Public Health
#26
JOURNAL ARTICLE
Keren Skalsky, Leor Perl, Tali Steinmetz, Benaya Rozen Zvi, Mohamad Atamna, Yaron Shapira, Ran Kornowski, Arthur Shiyovich, Ruth Rahamimov, Mordehay Vaturi
RATIONALE & OBJECTIVE: Kidney function can be adversely affected by significant tricuspid regurgitation (TR) owing to effects on cardiac output and systemic venous congestion. However, the impact of significant TR on short- and long-term kidney function following a kidney transplant remains uncertain. STUDY DESIGN: Retrospective observational cohort. SETTING & PARTICIPANTS: Kidney transplant recipients from a single center between 2016 and 2019...
May 2024: Kidney medicine
#27
JOURNAL ARTICLE
Carla Ramirez-Amoros, Maria San Basilio, Virginia Amesty, Susana Rivas, Roberto Lobato, Carlota Fernandez-Camblor, Pedro Lopez-Pereira, Maria Jose Martinez-Urrutia
BACKGROUND: Renal transplantation is currently the best treatment option for patients with end-stage renal disease. However, the use of kidneys from donors under 6 years of age as a possibility to increase the organ pool in pediatric recipients remains a controversial matter. We aimed to investigate whether donor age is associated to the long-term functionality of the renal graft. Likewise, we analyzed the adaptation of the graft to the ascending functional requirements in the pediatric patient...
May 2024: Pediatric Transplantation
#28
JOURNAL ARTICLE
Bright Benfor, Eric K Peden
No abstract text is available yet for this article.
April 17, 2024: Texas Heart Institute Journal
#29
JOURNAL ARTICLE
Noemi Glarner, Christian Puelacher, Danielle M Gualandro, Mirjam Pargger, Gabrielle Huré, Silvia Maiorano, Ivo Strebel, Simona Fried, Daniel Bolliger, Luzius A Steiner, Andreas Lampart, Giovanna Lurati Buse, Edin Mujagic, Didier Lardinois, Christoph Kindler, Lorenz Guerke, Stefan Schaeren, Andreas Mueller, Martin Clauss, Andreas Buser, Angelika Hammerer-Lercher, Christian Mueller
INTRODUCTION: Cardiac complications after major noncardiac surgery are common and associated with high morbidity and mortality. How preoperative use of beta-blockers may impact perioperative cardiac complications remains unclear. METHODS: In a multicentre prospective cohort study, preoperative beta-blocker use was ascertained in consecutive patients at elevated cardiovascular risk undergoing major noncardiac surgery. Cardiac complications were prospectively monitored and centrally adjudicated by two independent experts...
April 15, 2024: British Journal of Anaesthesia
#30
REVIEW
Simona Sacco, Matteo Foschi, Raffaele Ornello, Federico De Santis, Riccardo Pofi, Michele Romoli
Diabetes mellitus is a significant risk factor for both ischaemic and haemorrhagic stroke, affecting up to a third of individuals with cerebrovascular diseases. Beyond being a risk factor for stroke, diabetes and hyperglycaemia have a negative impact on outcomes after ischaemic and haemorrhagic stroke. Hyperglycaemia during the acute ischaemic stroke phase is associated with a higher risk of haemorrhagic transformation and poor functional outcome, with evidence in favour of early intervention to limit and manage severe hyperglycaemia...
April 16, 2024: Diabetologia
#31
JOURNAL ARTICLE
Yizeng Xu, Fang Lu, Meng Wang, Lingchen Wang, Chaoyang Ye, Shuohui Yang, Chen Wang
Background: Renal hypoxia plays a key role in the progression of chronic kidney disease (CKD). Shen Shuai II Recipe (SSR) has shown good results in the treatment of CKD as a common herbal formula. This study aimed to explore the effect of SSR on renal hypoxia and injury in CKD rats. Methods: Twenty-five Wistar rats underwent 5/6 renal ablation/infarction (A/I) surgery were randomly divided into three groups: 5/6 (A/I), 5/6 (A/I) + losartan (LOS), and 5/6 (A/I) + SSR groups. Another eight normal rats were used as the Sham group...
December 2024: Renal Failure
#32
JOURNAL ARTICLE
Stephen R Ash, Daniel Batlle, Jessica Kendrick, Yemisi Oluwatosin, Laura Kooienga, James M Eudicone, Anna-Karin Sundin, Emily Guerrieri, Linda F Fried
BACKGROUND: Metabolic acidosis and hyperkalemia are common in chronic kidney disease (CKD). A potential dual effect of sodium zirconium cyclosilicate (SZC), a selective binder of potassium in the gastrointestinal tract, on serum potassium (sK+) and serum bicarbonate (sHCO3-) was evaluated in patients with hyperkalemia and metabolic acidosis associated with CKD. METHODS: In the NEUTRALIZE study (NCT04727528), non-dialysis patients with stage 3-5 CKD, hyperkalemia (sK+ >5...
April 16, 2024: Kidney360
#33
JOURNAL ARTICLE
Sen-Jie Zhong, Xin-Yuan Zhao, Xiang Gao, Ru-Yin Huang, Jie Chen, Hui Wu, Hong-Cheng Fang, Shao-Xiang Xian
The clinical data of coronary heart disease(CHD) patients treated in the First Affiliated Hospital of Guangzhou University of Chinese Medicine and Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine from January 2022 to March 2023 were retrospectively collected. This study involved the descriptive analysis of demographic characteristics, clinical symptoms, and tongue and pulse features. The χ~2 test was conducted to analyze the distribution of syndrome elements and their combinations at diffe-rent stages of CHD, so as to reveal the clinical characteristics and syndrome patterns at various pathological stages of CHD...
March 2024: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
#34
JOURNAL ARTICLE
Jinxia Liu, Jane MacNaughtan, Annarein J C Kerbert, Theo Portlock, Javier Martínez Gonzalez, Yi Jin, Frederick Clasen, Abeba Habtesion, Huoyan Ji, Qin Jin, Alexandra Phillips, Francesco De Chiara, Ganesh Ingavle, Cesar Jimenez, Giacomo Zaccherini, Katherine Husi, Miguel Angel Rodriguez Gandia, Paul Cordero, Junpei Soeda, Lynda McConaghy, Jude Oben, Karen Church, Jia V Li, Haifeng Wu, Aarti Jalan, Pere Gines, Elsa Solà, Simon Eaton, Carrie Morgan, Michal Kowalski, Daniel Green, Amir Gander, Lindsey A Edwards, I Jane Cox, Helena Cortez-Pinto, Thomas Avery, Reiner Wiest, Francois Durand, Paolo Caraceni, Roberto Elosua, Joan Vila, Marco Pavesi, Vicente Arroyo, Nathan Davies, Rajeshwar P Mookerjee, Victor Vargas, Susan Sandeman, Gautam Mehta, Saeed Shoaie, Julian Marchesi, Agustín Albillos, Fausto Andreola, Rajiv Jalan
OBJECTIVE: Targeting bacterial translocation in cirrhosis is limited to antibiotics with risk of antimicrobial resistance. This study explored the therapeutic potential of a non-absorbable, gut-restricted, engineered carbon bead adsorbent, Yaq-001 in models of cirrhosis and acute-on-chronic liver failure (ACLF) and, its safety and tolerability in a clinical trial in cirrhosis. DESIGN: Performance of Yaq-001 was evaluated in vitro . Two-rat models of cirrhosis and ACLF, (4 weeks, bile duct ligation with or without lipopolysaccharide), receiving Yaq-001 for 2 weeks; and two-mouse models of cirrhosis (6-week and 12-week carbon tetrachloride (CCl4)) receiving Yaq-001 for 6 weeks were studied...
April 15, 2024: Gut
#35
JOURNAL ARTICLE
Ping Liu, Simon Sawhney, Uffe Heide-Jørgensen, Robert Ross Quinn, Simon Kok Jensen, Andrew Mclean, Christian Fynbo Christiansen, Thomas Alexander Gerds, Pietro Ravani
OBJECTIVE: To train and test a super learner strategy for risk prediction of kidney failure and mortality in people with incident moderate to severe chronic kidney disease (stage G3b to G4). DESIGN: Multinational, longitudinal, population based, cohort study. SETTINGS: Linked population health data from Canada (training and temporal testing), and Denmark and Scotland (geographical testing). PARTICIPANTS: People with newly recorded chronic kidney disease at stage G3b-G4, estimated glomerular filtration rate (eGFR) 15-44 mL/min/1...
April 15, 2024: BMJ: British Medical Journal
#36
JOURNAL ARTICLE
Thomas Alexander Gerds, Pietro Ravani
No abstract text is available yet for this article.
April 15, 2024: BMJ: British Medical Journal
#37
JOURNAL ARTICLE
Ghada Ankawi, Sean M Bagshaw, Rinaldo Bellomo, Ian Baldwin, Rajit Basu, Gabriella Bottari, Vincenzo Cantaluppi, William Clark, Silvia De Rosa, Lui G Forni, Dana Fuhrman, Stuart Goldstein, Hernando Gomez, Faeq Husain-Syed, Michael Joannidis, Kianoush Kashani, Anna Lorenzin, Ravindra Mehta, Patrick T Murray, Ragi Murugan, Marlies Ostermann, Neesh Pannu, Vedran Premuzic, John Prowle, Thiago Reis, Thomas Rimmelé, Claudio Ronco, Mitch Rosner, Antoine Schneider, Emily See, Danielle Soranno, Gianluca Villa, Adam Whaley-Connell, Alexander Zarbock
Adsorption-based extracorporeal therapies have been subject to technical developments and clinical application for close to five decades. More recently, new technological developments in membrane and sorbent manipulation have made it possible to deliver more biocompatible extracorporeal adsorption therapies to patients with a variety of conditions. There are several key rationales based on physicochemical principles and clinical considerations that justify the application and investigation of such therapies as evidenced by multiple ex-vivo, experimental, and clinical observations...
April 15, 2024: Nephrology, Dialysis, Transplantation
#38
JOURNAL ARTICLE
Ali A M AlHabobi, Ashwaq M S Almutairi, Danah A S Y Bohemid, Ashwini R Sehgal
This article highlights a selection of important nephrology studies published in 2023 that have relevance for nonnephrologist physicians. Four studies examined progression of chronic kidney disease or cardiovascular disease with respect to finerenone use, magnesium supplementation, iron markers, and COVID-19. Two studies examined treatments to improve specific aspects of chronic kidney disease management, including daprodustat to address anemia and patiromer to address hyperphosphatemia. One study showed that acetazolamide added to loop diuretics increased diuresis in acute decompensated heart failure across a wide range of renal function...
April 16, 2024: Annals of Internal Medicine
#39
JOURNAL ARTICLE
Balagangadhar R Totapally, Seevitha Totapalli, Prithvi Sendi, Paul A Martinez
OBJECTIVE: The study aimed to explore the prevalence, clinical features, resource utilization, temporal trends and outcomes associated with adenoviral infections in hospitalized children. METHODS: A retrospective analysis using the Healthcare Cost and Utilization Project's Kids' Inpatient Database from 1997 to 2019 was performed. Children aged 29 days to 17 years with adenoviral infection were selected. Chi-square, Kruskal-Wallis tests, linear trend analysis and multivariable analysis were used for data analysis...
April 11, 2024: Pediatric Infectious Disease Journal
#40
REVIEW
Racquel Lowe-Jones, Isabelle Ethier, Lori-Ann Fisher, Michelle M Y Wong, Stephanie Thompson, Georges Nakhoul, Shaifali Sandal, Rahul Chanchlani, Sara N Davison, Anukul Ghimire, Kailash Jindal, Mohamed A Osman, Parnian Riaz, Syed Saad, Stephen M Sozio, Somkanya Tungsanga, Alexandra Cambier, Silvia Arruebo, Aminu K Bello, Fergus J Caskey, Sandrine Damster, Jo-Ann Donner, Vivekanand Jha, David W Johnson, Adeera Levin, Charu Malik, Masaomi Nangaku, Ikechi G Okpechi, Marcello Tonelli, Feng Ye, Rulan S Parekh, Shuchi Anand
The International Society of Nephrology Global Kidney Health Atlas charts the availability and capacity of kidney care globally. In the North America and the Caribbean region, the Atlas can identify opportunities for kidney care improvement, particularly in Caribbean countries where structures for systematic data collection are lacking. In this third iteration, respondents from 12 of 18 countries from the region reported a 2-fold higher than global median prevalence of dialysis and transplantation, and a 3-fold higher than global median prevalence of dialysis centers...
April 2024: Kidney International Supplements
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
