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Takayasu arteritis

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https://www.readbyqxmd.com/read/28913687/non-atherosclerotic-vascular-disease-in-women
#1
REVIEW
Lee Joseph, Esther S H Kim
Takayasu arteritis, fibromuscular dysplasia (FMD), spontaneous arterial dissection, Raynaud's phenomenon, and chilblains are vascular conditions that are associated with an increased predisposition in women and are often underdiagnosed. Takayasu arteritis has an incidence rate of 2.6 cases per million individuals per year in the USA and predominantly affects women of childbearing age. HLA-B5 genetic locus is linked with Takayasu arteritis susceptibility. Methods to determine active disease are limiting; currently utilized clinical and imaging findings and laboratory tests are of limited value for this purpose...
September 14, 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28903623/endovascular-stenting-of-mid-aortic-syndrome-due-to-takayasu-arteritis
#2
Ali Dogan, Kenan Sever, Emrah Ozdemir, Denyan Mansuroglu, Nuri Kurtoglu
Introduction-patients: Takayasu arteritis may involve various parts of the aorta and its major branches. It leads to occlusive or aneurysmal disease of the vessel. It can be treated either with surgery or percutaneous intervention. We report a successful endovascular treatment of stenosis of the descending thoracic and abdominal aorta in a 19-year-old female. Methods-results-conclusions: Self-expandable nitinol stent was deployed and adequate opening of the aorta was obtained in this patient. Long-term durability of endovascular approach is a matter of debate...
September 13, 2017: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/28895653/clinical-interventions-for-takayasu-arteritis-a-systematic-review
#3
REVIEW
Rafael L Pacheco, Carolina de Oliveira Cruz Latorraca, Alexandre Wagner Silva de Souza, Daniela V Pachito, Rachel Riera
INTRODUCTION: Takayasu arteritis (TA) is a rare systemic vasculitis that affects large vessels often resistant to treatment and associated with high morbidity and mortality. Treatment is defied by the relapsing nature of the disease and frequent adverse effects of corticosteroids and immunosuppressors, rendering failure of treatment in a significant portion of patients. Considering the low quantity and quality of published studies focusing on treatment of TA, synthesis and critical assessment of the available evidence is fundamental to establish recommendations for clinical practice...
September 12, 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28895041/unmet-needs-in-the-pathogenesis-and-treatment-of-vasculitides
#4
REVIEW
Francesco Muratore, Giulia Pazzola, Alessandra Soriano, Nicolò Pipitone, Stefania Croci, Martina Bonacini, Luigi Boiardi, Carlo Salvarani
Despite the progress in the last years on the field of vasculitides, there are several unmet needs regarding classification, disease activity assessment, predictors of flares and complications, and type of treatment for the different forms. The 1990 American College of Rheumatology (ACR) classification criteria currently used to define giant cell arteritis and Takayasu arteritis were designed to discriminate between different types of vasculitides but not to differentiate vasculitis from other disorders. Recently, efforts have been made to overcome the shortcomings of the ACR criteria...
September 11, 2017: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/28874185/a-novel-susceptibility-locus-in-the-il12b-region-is-associated-with-the-pathophysiology-of-takayasu-arteritis-through-il-12p40-and-il-12p70-production
#5
Toshiki Nakajima, Hajime Yoshifuji, Masakazu Shimizu, Koji Kitagori, Kosaku Murakami, Ran Nakashima, Yoshitaka Imura, Masao Tanaka, Koichiro Ohmura, Fumihiko Matsuda, Chikashi Terao, Tsuneyo Mimori
BACKGROUND: A previous study revealed the association between susceptibility to Takayasu arteritis (TAK) and a single nucleotide polymorphism (SNP) rs6871626 located in IL12B, which encodes interleukin (IL)-12p40, a common component of IL-12p70 and IL-23. We investigated the expression of these cytokines in patients with TAK, stratifying them into those with or without the risk allele at the rs6871626 SNP. METHODS: Plasma levels of IL-12p40, IL-12p70, and IL-23 were quantified in 44 patients with TAK and 19 healthy controls (HCs) by enzyme-linked immunosorbent assays...
September 6, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28869412/prevalence-of-takayasu-s-arteritis-in-korea
#6
Shin Yi Jang, Su Ra Seo, Seung Woo Park, Duk Kyung Kim
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August 31, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28868078/clinical-features-of-aortic-dissection-associated-with-takayasu-s-arteritis
#7
Xue-Ping Wu, Ping Zhu
No abstract text is available yet for this article.
July 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/28864648/assessment-of-disease-activity-in-large-vessel-vasculitis-results-of-an-international-delphi-exercise
#8
Sibel Z Aydin, Haner Direskeneli, Peter A Merkel
OBJECTIVE: To arrive at consensus for candidate outcomes for disease activity assessment in large-vessel vasculitis (LVV) in clinical trials. METHODS: A Delphi survey including 99 items was circulated among international experts for 3 rounds. RESULTS: Fifty-seven items were accepted for both giant cell arteritis and Takayasu arteritis. Sixty-seven percent of experts voted to have a common approach for both diseases with additional disease-specific items such as weight loss, scalp tenderness/necrosis, morning stiffness, dizziness, visual symptoms, and imaging...
September 1, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28864646/development-of-a-core-set-of-outcome-measures-for-large-vessel-vasculitis-report-from-omeract-2016
#9
Antoine G Sreih, Fatma Alibaz-Oner, Tanaz A Kermani, Sibel Z Aydin, Peter F Cronholm, Trocon Davis, Ebony Easley, Ahmet Gul, Alfred Mahr, Carol A McAlear, Nataliya Milman, Joanna C Robson, Gunnar Tomasson, Haner Direskeneli, Peter A Merkel
OBJECTIVE: Among the challenges in conducting clinical trials in large-vessel vasculitis (LVV), including both giant cell arteritis (GCA) and Takayasu arteritis (TA), is the lack of standardized and meaningful outcome measures. The Outcome Measures in Rheumatology (OMERACT) Vasculitis Working Group initiated an international effort to develop and validate data-driven outcome tools for clinical investigation in LVV. METHODS: An international Delphi exercise was completed to gather opinions from clinical experts on LVV-related domains considered important to measure in trials...
September 1, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28863945/the-renal-artery-is-involved-in-chinese-takayasu-s-arteritis-patients
#10
Zhe Chen, Jing Li, Yunjiao Yang, Hongchao Li, Jiuliang Zhao, Fei Sun, Mengtao Li, Xinping Tian, Xiaofeng Zeng
Takayasu's arteritis is a rare systemic vasculitis mainly affecting the aorta and its major branches. Previous studies have suggested that almost half of the Asian Takayasu's patients have renal artery involvement. However, due to the rarity of the disease, little is known about renal artery involvement in Chinese Takayasu's arteritis patients. Here, we retrospectively reviewed and analyzed 411 patients diagnosed with Takayasu's arteritis in our center to explore the clinical features of renal artery involvement in this group of patients...
August 30, 2017: Kidney International
https://www.readbyqxmd.com/read/28859604/diagnosis-management-and-outcome-of-aortitis-at-a-single-center
#11
Nedaa Skeik, Claire A Ostertag-Hill, Ross F Garberich, Peter B Alden, Jason Q Alexander, Andrew H Cragg, Jesse M Manunga, Elliot J Stephenson, Jessica M Titus, Timothy M Sullivan
BACKGROUND: Aortitis is a rare condition with inflammatory or infectious etiology that can be difficult to diagnose due to the highly variable clinical presentation and nonspecific symptoms. However, current literature on the diagnosis, management, and prognosis of aortitis is extremely scarce. METHODS: We retrospectively reviewed all patients' charts who were diagnosed with giant cell arteritis, Takayasu arteritis, or noninfectious aortitis presenting at a single center between January 1, 2009, and April 17, 2015...
January 1, 2017: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28857274/aortic-root-replacement-with-left-main-trunk-reconstruction-using-autologous-pericardial-cuff-technique-for-ostial-stenosis-in-takayasu-s-arteritis
#12
Yutaka Iba, Akira Yamada, Naritomo Nishioka, Kosuke Ujihira, Katsuhiko Nakanishi
No abstract text is available yet for this article.
August 30, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/28856429/effect-of-crp-value-on-18-f-fdg-pet-vascular-positivity-in-takayasu-arteritis-a-systematic-review-and-per-patient-based-meta-analysis
#13
REVIEW
Léa Gomez, Philippe Chaumet-Riffaud, Nicolas Noel, Olivier Lambotte, Cécile Goujard, Emmanuel Durand, Florent L Besson
PURPOSE: The aim of this study was to quantify the association between the CRP value and (18)F-FDG PET vascular positivity in Takayasu arteritis (TAK) through a structured dedicated systematic review and meta-analysis. METHODS: From January 2000 to December 2016, the PubMed/MEDLINE database was searched for articles specifically dealing with the assessment of vascular inflammation using (18)F-FDG PET and CRP biomarkers in TAK. Inclusion criteria for the qualitative analysis were (1) (18)F-FDG PET used to assess the disease activity, (2) The use of the ACR criteria for the diagnosis of TAK, (3) No case mixed vasculitis (i...
August 30, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28854963/takayasu-s-arteritis-a-case-with-relapse-after-urgent-coronary-revascularization
#14
Klaus Empen, Astrid Hummel, Daniel Beug, Stephan B Felix, Mathias C Busch, Piotr M Kaczmarek
BACKGROUND: Vasculitides are commonly unrecognized causes of coronary stenosis and myocardial ischemia. We report on a 24-year old patient with Takayasu's arteritis who underwent urgent percutaneous coronary intervention, suffered from symptomatic restenosis of the left main coronary artery during standard immunosuppressive therapy. CASE PRESENTATION: A 24-year old woman was referred for coronary angiography because of typical progressive angina pectoris. On bicycle ergometry, there were both reproducible symptoms and deep ST segment depressions on precordial leads...
July 25, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28851714/takayasu-arteritis-presenting-as-embolic-stroke
#15
Kristina Field, Laila Gharzai, Kaye Bardeloza, Bruce Houghton
A 52-year-old Caucasian woman presented to the emergency department with symptoms of acute ischaemic stroke (right-side weakness, confusion and aphasia) that resolved completely after administration of tissue plasminogen activator. During stroke work-up, she was found to have an enhancing infiltrate of the aorta at the level of the take-off of the great vessels, most consistent with early Takayasu arteritis. After being discharged home on steroids and dual antiplatelet therapy, she returned 2 days later with re-presentation of weakness and aphasia...
August 28, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28843640/takayasu-s-arteritis-a-new-era-is-approaching
#16
EDITORIAL
Haner Direskeneli
No abstract text is available yet for this article.
July 2017: La Presse Médicale
https://www.readbyqxmd.com/read/28835567/closing-the-brief-case-scopulariopsis-endocarditis-a-case-of-mistaken-takayasu-s-arteritis
#17
EDITORIAL
Miguel A Arroyo, Timothy B Walls, Ryan F Relich, Thomas E Davis, Bryan H Schmitt
No abstract text is available yet for this article.
September 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28835565/the-brief-case-scopulariopsis-endocarditis-a-case-of-mistaken-takayasu-s-arteritis
#18
EDITORIAL
Miguel A Arroyo, Timothy B Walls, Ryan F Relich, Thomas E Davis, Bryan H Schmitt
No abstract text is available yet for this article.
September 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28811356/clinical-characteristics-of-heart-involvement-in-chinese-patients-with-takayasu-arteritis
#19
Jing Li, Hongchao Li, Fei Sun, Zhe Chen, Yunjiao Yang, Jiuliang Zhao, Mengtao Li, Xinping Tian, Xiaofeng Zeng
OBJECTIVE: To understand the characteristics of heart involvement in Chinese patients with Takayasu arteritis (TA). METHODS: The medical charts of 411 patients with TA (325 women, 86 men) were retrospectively reviewed. The comparison of clinical manifestations was carried out between the patients with TA with (n = 164) and without (n = 247) heart involvement. RESULTS: The median age at disease onset was 23.0 years (18.0-30.0) in 411 patients with TA, and 23...
August 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28803683/immune-response-in-takayasu-arteritis
#20
Tristan Mirault, Henri Guillet, Emmanuel Messas
Takayasu arteritis (TAK) is a vasculitis of the large arteries. The arterial wall, target of the immune reaction, is composed of vascular dendritic cells, endothelial cells, vascular smooth muscle cells and fibroblasts, which engage in an interaction with T cells and macrophages to, ultimately, cause luminal stenosis or aneurysmal wall damage of the vessel. A multitude of cytokines have been identified to increase in case of TAK and to be linked to disease activity. A better understanding of the physiopathological pathways and mechanisms involved, might enable a more tailored therapeutic approach in TAK...
July 2017: La Presse Médicale
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