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bowel preparation colonoscopy

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https://www.readbyqxmd.com/read/28428714/predictors-for-difficult-cecal-insertion-in-colonoscopy-the-impact-of-obesity-indices
#1
Soo Yun Moon, Byung Chang Kim, Dae Kyung Sohn, Kyung Su Han, Bun Kim, Chang Won Hong, Bum Joon Park, Kum Hei Ryu, Ji Hyung Nam
AIM: To identify the factors influencing cecal insertion time (CIT) and to evaluate the effect of obesity indices on CIT. METHODS: We retrospectively reviewed the data for participants who received both colonoscopy and abdominal computed tomography (CT) from February 2008 to May 2008 as part of a comprehensive health screening program. Age, gender, obesity indices [body mass index (BMI), waist-to-hip circumference ratio (WHR), waist circumference (WC), visceral adipose tissue (VAT) volume and subcutaneous adipose tissue (SAT) volume on abdominal CT], history of prior abdominal surgery, constipation, experience of the colonoscopist, quality of bowel preparation, diverticulosis and time required to reach the cecum were analyzed...
April 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28408995/multiple-zonal-and-multi-zone-adenoma-detection-rates-according-to-quality-of-cleansing-during-colonoscopy
#2
Stefano Pontone, Cesare Hassan, Roberta Maselli, Paolo Pontone, Rita Angelini, Manuela Brighi, Gregorio Patrizi, Daniele Pironi, Fabio Massimo Magliocca, Angelo Filippini
BACKGROUND: The safety and diagnostic accuracy of colonoscopy depend on the quality of colon cleansing. The adenoma detection rate is usually used as a quality measurement score. OBJECTIVE: We aimed to introduce and evaluate three new parameters to determine polyps and adenomas segmental localization and their distribution in association with different bowel preparation levels during colonoscopy. We introduce the multiple adenoma detection rate (the percentage of patients with >2 adenomas diagnosed during colonoscopy), the zonal adenoma detection rate (the percentage of patients with >2 adenomas diagnosed during colonoscopy in different colon areas (rectum, sigmoid, descending, transverse, ascending and cecum colon)), and multi-zone adenoma detection rate (the percentage of patients with >2 adenomas diagnosed during colonoscopy in different colon areas with at least a segment between them with or without lesions (i...
December 2016: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/28396341/bioactivity-of-oral-linaclotide-in-human-colorectum-for-cancer-chemoprevention
#3
David S Weinberg, Jieru E Lin, Nathan R Foster, Gary J Della'Zanna, Asad Umar, Drew K Seisler, Walter K Kraft, David M Kastenberg, Leo C Katz, Paul J Limburg, Scott A Waldman
Guanylate cyclase C (GUCY2C) is a tumor suppressing receptor silenced by loss of expression of its luminocrine hormones guanylin and uroguanylin early in colorectal carcinogenesis. This observation suggests oral replacement with a GUCY2C agonist may be an effective targeted chemoprevention agent. Linaclotide is an FDA approved oral GUCY2C agonist formulated for gastric release, inducing fluid secretion into the small bowel to treat chronic idiopathic constipation. The ability of oral linaclotide to induce a pharmacodynamic response in epithelial cells of the colorectum in humans remains undefined...
April 10, 2017: Cancer Prevention Research
https://www.readbyqxmd.com/read/28393103/efficacy-and-safety-of-picoprep-tailored-dosing-compared-with-picoprep-day-before-dosing-for-colon-cleansing-a-multi-centric-randomised-study
#4
Ralf Kiesslich, Stefan Schubert, Michael Mross, Tobias Klugmann, Michael Klemt-Kropp, Imke Behnken, Gillaume Bonnaud, Eric Keulen, Marcel Groenen, Michael Blaker, Thierry Ponchon, Wilfred Landry, Meredin Stoltenberg
Background and study aims The success of any colonoscopy procedure depends upon the quality of bowel preparation. We evaluated the efficacy and safety of a new tailored dosing (TD) regimen compared with the approved PICOPREP day-before dosing regimen (DBD) in the European Union. Patient and methods Patients (≥ 18 years) undergoing colonoscopy were randomised (2:1) to TD (Dose 1, 10 - 18 hours; Dose 2, 4 - 6 hours before colonoscopy) or DBD (Dose 1 before 8:00AM on the day before colonoscopy; Dose 2, 6 - 8 hours after Dose 1)...
April 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28390559/optimal-timing-for-faecal-tagging-in-same-day-ct-colonography-for-patients-with-failed-colonoscopy
#5
Sushant Saluja, Grazvydas Gaikstas, Milan Sapundzieski
AIM: Same day CT colonography (CTC) for incomplete colonoscopy should be considered to avoid the need for further bowel preparation. Oral administration of contrast is essential for optimal colonic analysis of the CTC. Our aim was to determine the optimal time for giving contrast to people who underwent same day CTC after failed colonoscopy. METHODS: Data was extracted from the Trust database to identify the number of CTC referrals following failed or incomplete colonoscopy within the last 5 years, and the reason for their referral...
May 2017: Radiography
https://www.readbyqxmd.com/read/28382323/the-impact-of-diet-liberalization-on-bowel-preparation-for-colonoscopy
#6
James Walter, Gloria Francis, Rebecca Matro, Ramalinga Kedika, Rachael Grosso, Scott W Keith, David Kastenberg
Background and study aims Dietary restrictions are integral to colonoscopy preparation and impact patient satisfaction. Utilizing split-dose, lower-volume polyethylene glycol 3350-electrolyte solution (PEG-ELS), this study compared colon preparation adequacy of a low-residue diet to clear liquids using a validated grading scale. Patients and methods This was a prospective, randomized, single-blinded, single-center non-inferiority study evaluating diet the day prior to outpatient colonoscopy. Subjects were randomized to a Low-Residue diet for breakfast and lunch, or Clears only...
April 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28379020/-contribution-of-ct-colonography-to-clinical-practice
#7
Lukáš Lambert, Lucie Šimáková
CT colonography is a CT examination focused on the detection of colonic polyps and masses. Its most common indications include incomplete optical colonoscopy and generally personal preference in symptomatic or frail patients. CT colonography has a diagnostic yield similar to optical colonoscopy. It is less demanding for the patient, has shorter examination times, lower rates of adverse effects (including bowel perforation) and allows limited evaluation of extracolonic structures. In 10-15 % of asymptomatic patients, optical colonoscopy is needed if either a colonic polyp or mass is detected...
2017: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/28376974/impact-of-health-literacy-directed-colonoscopy-bowel-preparation-instruction-sheet
#8
Terry C Davis, Jill Hancock, James Morris, Perry Branim, Abhishek Seth, Alfred Rademaker, Connie L Arnold
OBJECTIVES: To improve patient colonoscopy bowel preparation with a newly developed simplified instruction sheet in a safety-net hospital system. METHODS: Bowel preparation quality was compared in a retrospective chart review of 543 patients, 287 of whom received standard instructions (9th grade reading level) between November 2015 and February 2016, and 256 of whom received simplified instructions (6th grade level) between March and May 2016. Instructions were mailed to all patients...
May 1, 2017: American Journal of Health Behavior
https://www.readbyqxmd.com/read/28376885/citrobacter-braakii-bacteremia-induced-septic-shock-after-colonoscopy-preparation-with-polyethylene-glycol-in-a-critically-ill-patient-a-case-report
#9
Tetsuya Yumoto, Yoshiyasu Kono, Seiji Kawano, Chihiro Kamoi, Atsuyoshi Iida, Motoko Nose, Keiji Sato, Toyomu Ugawa, Hiroyuki Okada, Yoshihito Ujike, Atsunori Nakao
BACKGROUND: Polyethylene glycol (PEG) is widely used for bowel cleaning in preparation for colonoscopy because of its safety. Septic shock after PEG preparation is an extremely rare complication. Herein, we describe a case of septic shock that occurred immediately after colonoscopy preparation with PEG. CASE PRESENTATION: A 75-year-old Japanese male who had previously developed diabetes after total pancreatectomy received PEG in preparation for colonoscopy. He had been admitted to the emergency intensive care unit 4 days earlier due to hematochezia presenting with shock...
April 4, 2017: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/28366050/a-safe-and-effective-multi-day-colonoscopy-bowel-preparation-for-individuals-with-spinal-cord-injuries
#10
Shawn H Song, Jelena N Svircev, Brandon J Teng, Jason A Dominitz, Stephen P Burns
CONTEXT/OBJECTIVE: Colonoscopy with polypectomy is associated with a reduced risk of colorectal cancer (CRC), but poor bowel cleansing limits the diagnostic yield of the procedure. Patients with spinal cord injury (SCI) frequently have suboptimal bowel cleansing with standard pre-colonoscopy bowel preparation regimens. We aimed to assess the safety, tolerability, and efficacy of a multi-day inpatient bowel preparation regimen in a population of patients with SCI. DESIGN: Retrospective case series...
April 1, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28328936/polyp-detection-rate-in-transverse-and-sigmoid-colon-significantly-increases-with-longer-withdrawal-time-during-screening-colonoscopy
#11
Kazuhiro Kashiwagi, Nagamu Inoue, Toshifumi Yoshida, Rieko Bessyo, Kazuaki Yoneno, Hiroyuki Imaeda, Haruhiko Ogata, Takanori Kanai, Yoshinori Sugino, Yasushi Iwao
BACKGROUND: The guidelines for colonoscopy present withdrawal time (WT) and adenoma detection rate (ADR) as the quality indicator. The purpose of this retrospective study is to analyze the predicting factors with polyp detection rate (PDR) as a surrogate for ADR by using comprehensive health checkup data, and assess the correlation between PDR per each colonic segment and WT, and factors influencing WT. METHODS: One thousand and thirty six consecutive health checkup cases from April 2015 to March 2016 were enrolled in this study, and 880 subjects who undertook colonoscopy without polyp removal or biopsy were divided into the two groups (polyp not detected group vs polyp detected group)...
2017: PloS One
https://www.readbyqxmd.com/read/28291237/comparison-of-two-intensive-bowel-cleansing-regimens-in-patients-with-previous-poor-bowel-preparation-a-randomized-controlled-study
#12
Antonio Z Gimeno-García, Goretti Hernandez, Ana Aldea, David Nicolás-Pérez, Alejandro Jiménez, Marta Carrillo, Vanesa Felipe, Onofre Alarcón-Fernández, Manuel Hernandez-Guerra, Rafael Romero, Inmaculada Alonso, Yanira Gonzalez, Zaida Adrian, Miguel Moreno, Laura Ramos, Enrique Quintero
OBJECTIVES: Inadequate bowel cleansing is a major burden for endoscopy units. The aim of this study was to compare two intensive bowel cleansing regimens in patients with previous colonoscopy with inadequate bowel preparation. METHODS: Patients with inadequate cleansing at index colonoscopy were randomized to 4-L split-dose polyethylene-glycol (PEG) regimen vs. 2-L split-dose PEG plus ascorbic acid (PEG+Asc) regimen. All individuals underwent a 3-day low-residue diet and received 10 mg of bisacodyl, the day before colonoscopy...
March 14, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28286937/early-versus-late-bedside-endoscopy-for-gastrointestinal-bleeding-in-critically-ill-patients
#13
Jee Hyun Kim, Ji Hye Kim, Jaeyoung Chun, Changhyun Lee, Jong Pil Im, Joo Sung Kim
Background/Aims: Gastrointestinal (GI) bleeding is a life-threatening complication in critically ill patients. The aim of this study was to determine the efficacy of bedside endoscopy in an intensive care unit (ICU) setting, and to compare the outcomes of early endoscopy (within 24 hours of detecting GI bleeding) with late endoscopy (after 24 hours). Methods: We retrospectively reviewed the medical records of patients who underwent bedside endoscopy for nonvariceal upper GI bleeding and lower GI bleeding that occurred after ICU admission at Seoul National University Hospital from January 2010 to May 2015...
March 15, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/28284884/risk-of-advanced-lesions-at-the-first-follow-up-colonoscopy-after-polypectomy-of-diminutive-versus-small-adenomatous-polyps-of-low-grade-dysplasia
#14
Orly Sneh Arbib, Valentina Zemser, Yaara Leibovici Weissman, Rachel Gingold-Belfer, Alex Vilkin, Sapir Eizenstein, Arnon Cohen, Doron Comaneshter, Shochat Tzipora, Yaron Niv, Yeuda Ringel, David Lieberman, Zohar Levi
BACKGROUND AND AIMS: The current guidelines for surveillance after polypectomy do not distinguish between diminutive (1-5 mm) and small (6-9 mm) polyps with low-grade dysplasia (LGD). We aimed to evaluate the risk for advanced neoplasia on follow-up colonoscopy. METHODS: We retrospectively analyzed 443 patients whose worst finding at index colonoscopy was polypectomy of 1 to 5 or 6 to 9 mm polyps with LGD and those who underwent a follow-up colonoscopy. RESULTS: During a mean follow-up of 32...
March 8, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28282690/risk-factors-for-inadequate-bowel-preparation-a-validated-predictive-score
#15
Antonio Z Gimeno-García, Jose Luis Baute, Goretti Hernandez, Dalia Morales, Carmen Delia Gonzalez-Pérez, David Nicolás-Pérez, Onofre Alarcon-Fernández, Alejandro Jiménez, Manuel Hernandez-Guerra, Rafael Romero, Inmaculada Alonso, Yanira Gonzalez, Zaida Adrian, Marta Carrillo, Laura Ramos, Enrique Quintero
Background and study aim Inadequate bowel cleansing negatively affects the efficiency of colonoscopy in routine clinical practice. The aim of this study was to design and validate a predictive model for inadequate bowel cleanliness. Patients and methods The model was built from 667 consecutive outpatients (development cohort) who were prospectively scheduled for colonoscopy between June and September 2014. The validation cohort included 409 outpatients who underwent colonoscopy between October and December 2014...
March 10, 2017: Endoscopy
https://www.readbyqxmd.com/read/28282689/water-exchange-for-screening-colonoscopy-increases-adenoma-detection-rate-a-multicenter-double-blinded-randomized-controlled-trial
#16
Sergio Cadoni, Přemysl Falt, Emanuele Rondonotti, Franco Radaelli, Petr Fojtik, Paolo Gallittu, Mauro Liggi, Arnaldo Amato, Silvia Paggi, Vit Smajstrla, Ondřej Urban, Matteo Erriu, Malcolm Koo, Felix W Leung
Background and study aims Single-center studies, which were retrospective and/or involved unblinded colonoscopists, have suggested that water exchange, but not water immersion, compared with air insufflation significantly increases the adenoma detection rate (ADR), particularly in the proximal and right colon. Head-to-head comparison of the three techniques with ADR as primary outcome and blinded colonoscopists has not been reported to date. In a randomized controlled trial with blinded colonoscopists, we aimed to evaluate the impact of the three insertion techniques on ADR...
March 10, 2017: Endoscopy
https://www.readbyqxmd.com/read/28267011/comparative-evaluation-of-the-efficacy-of-polyethylene-glycol-with-ascorbic-acid-and-an-oral-sulfate-solution-in-a-split-method-for-bowel-preparation-a-randomized-multicenter-phase-iii-clinical-trial
#17
RANDOMIZED CONTROLLED TRIAL
Bun Kim, Seong Dae Lee, Kyung Su Han, Byung Chang Kim, Eui-Gon Youk, Myung Jin Nam, Doo Han Lee, Dae Kyung Sohn
BACKGROUND: An adequate level of bowel preparation before colonoscopy is important. The ideal agent for bowel preparation should be effective and tolerable. OBJECTIVE: The purpose of this study was to compare the clinical efficacy and tolerability of polyethylene glycol with ascorbic acid and oral sulfate solution in a split method for bowel preparation. DESIGN: This was a prospective, multicenter, randomized controlled clinical trial. SETTINGS: Outpatients at the specialized clinics were included...
April 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28265285/accuracy-of-colon-capsule-endoscopy-in-detecting-colorectal-polyps-in-individuals-with-familial-colorectal-cancer-could-we-avoid-colonoscopies
#18
Cristina Alvarez-Urturi, Gloria Fernández-Esparrach, Inés Ana Ibáñez, Cristina Rodríguez De Miguel, Josep Maria Dedeu, Xavier Bessa, Henry Córdova, Maria Pellisé, Francesc Balaguer, Angels Ginés, Luis Barranco, Isis K Araujo, Montserrat Andreu, Josep Llach, Antoni Castells, Begoña González-Suarez
Background. Individuals with a family history of colorectal cancer (CRC) have an increased risk of CRC. We evaluated the diagnostic yield of CCE in the detection of lesions and also two different colon preparations. Methods. A prospective multicenter study was designed to assess CCE diagnostic yield in a cohort of asymptomatic individuals with a family history of CRC. CCE and colonoscopy were performed on the same day by 2 endoscopists who were blinded to the results of the other procedure. Results. Fifty-three participants were enrolled...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28256902/the-role-of-colonoscopy-and-ct-colonography-in-patients-presenting-with-symptoms-of-constipation
#19
Kumaran Ratnasingham, Tammy Lo, Karim Jamal, Lavanya Varatharajan, Yasmin Tabbakh, Hussein Kaderbhai, Nicholas J West
OBJECTIVES: There is controversy whether constipation as a primary presenting complaint is an indication for diagnostic colonoscopy. Computed tomographic colonography (CTC) is a less invasive and more acceptable alternative. We compared the completion and sensitivity of colonoscopy with CTC in patients who presented with the primary symptom of constipation. METHOD: A retrospective study was conducted which examined the first 100 colonoscopies and 100 CTCs carried out for the primary symptom of constipation from June 2012 to December 2013...
March 3, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28256484/cecal-intubation-rate-during-colonoscopy-at-a-tertiary-hospital-in-south-west-nigeria-how-frequent-and-what-affects-completion-rate
#20
A Akere, K O Akande
BACKGROUND: Colonoscopy is useful in the diagnosis, treatment of colorectal diseases, and for colorectal cancer screening program. Complete colonoscopy is therefore crucial for the success of any screening program. One important measure of the quality of colonoscopy is the cecal intubation rate (CIR). AIM: This was to assess the CIR at our endoscopy unit and evaluate the factors responsible for uncompleted cases. PATIENTS AND METHODS: This was a prospective study at the endoscopy unit of the University College Hospital, Ibadan...
March 2017: Nigerian Journal of Clinical Practice
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