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Remote Memory

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https://www.readbyqxmd.com/read/29122206/the-evolution-of-accelerated-long-term-forgetting-evidence-from-the-time-study
#1
Sharon Savage, Serge Hoefeijzers, Fraser Milton, Claire Streatfield, Michaela Dewar, Adam Zeman
OBJECTIVE: Accelerated long-term forgetting (ALF) occurs when newly learned information decays faster than normal over extended delays. It has been recognised most frequently in temporal lobe epilepsy, including Transient Epileptic Amnesia (TEA), but can also be drug-induced. Little is known about the evolution of ALF over time and its impacts upon other memory functions, such as autobiographical memory (ABM). Here we investigate the long-term outcome of ALF and ABM in a group of patients with TEA and a single case of baclofen-induced ALF...
October 6, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/29115588/limb-remote-ischemic-post%C3%A2-conditioning-reduces-injury-and-improves-long%C3%A2-term-behavioral-recovery-in-rats-following-subarachnoid-hemorrhage-possible-involvement-of-the-autophagic-process
#2
Xiang Hu, Tao Lv, Shao-Feng Yang, Xiao-Hua Zhang, Yi-Feng Miao
Hemorrhage‑related neurologic injury is a primary cause of disability and mortality following subarachnoid hemorrhage (SAH). The aim of the present study was to investigate the potential neuroprotective effect and the possible role of autophagy in limb remote ischemic post‑conditioning (RIPostC) using an endovascular puncture rat model of SAH. RIPostC was induced by three cycles of occlusion (10 min) and release (10 min) in the bilateral femoral artery using an aneurysm clip. Early RIPostC began immediately following SAH, delayed RIPostC began following a 30 min delay and the repeated RIPostC group underwent the protocol every day for 3 days...
October 24, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29114278/profiling-cognitive-deficits-in-intra-axial-and-extra-axial-tumors-using-addenbrooke-s-cognitive-examination-as-a-screening-tool-an-indian-experience
#3
Sandhya Cherkil, Dilip Panikar, Deepak Kuttikkattu Soman
Background: Tumors of the brain, whether intra- or extra-axial, results in cognitive deficits. The aim of the present study was to profile cognitive deficits using Addenbrooke's Cognitive Examination-Malayalam (ACE-M) as a screen and to determine the sensitivity and specificity of the same. Methods: Seventy-four drug naïve patients diagnosed to have brain tumors were assessed for cognitive functioning using ACE-M before surgery. Results: Patients with high-grade intra-axial tumors showed a significant association on the cognitive domains of registration (0...
October 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29113572/effects-of-an-individual-12-week-community-located-start-to-run-program-on-physical-capacity-walking-fatigue-cognitive-function-brain-volumes-and-structures-in-persons-with-multiple-sclerosis
#4
Peter Feys, Lousin Moumdjian, Florian Van Halewyck, Inez Wens, Bert O Eijnde, Bart Van Wijmeersch, Veronica Popescu, Paul Van Asch
BACKGROUND: Exercise therapy studies in persons with multiple sclerosis (pwMS) primarily focused on motor outcomes in mid disease stage, while cognitive function and neural correlates were only limitedly addressed. OBJECTIVES: This pragmatic randomized controlled study investigated the effects of a remotely supervised community-located "start-to-run" program on physical and cognitive function, fatigue, quality of life, brain volume, and connectivity. METHOD: In all, 42 pwMS were randomized to either experimental (EXP) or waiting list control (WLC) group...
November 1, 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/29112951/phenotype-and-specificity-of-t-cells-in-primary-human-cytomegalovirus-infection-during-pregnancy-il-7rpos-long-term-memory-phenotype-is-associated-with-protection-from-vertical-transmission
#5
Federico Mele, Chiara Fornara, David Jarrossay, Milena Furione, Alessia Arossa, Arsenio Spinillo, Antonio Lanzavecchia, Giuseppe Gerna, Federica Sallusto, Daniele Lilleri
Congenital human cytomegalovirus (HCMV) infection is the major cause of birth defects and a precise definition of the HCMV-specific T-cell response in primary infection may help define reliable correlates of immune protection during pregnancy. In this study, a high throughput method was used to define the frequency of CD4+ and CD8+ T cells specific for four HCMV proteins in the naïve compartment of seronegative subjects and the effector/memory compartments of subjects with primary/remote HCMV infection. The naïve repertoire displayed comparable frequencies of T cells that were reactive with HCMV structural (pp65, gB and the pentamer gHgLpUL128L) and non-structural (IE-1) proteins...
2017: PloS One
https://www.readbyqxmd.com/read/29095692/long-term-recording-of-electromyographic-activity-from-multiple-muscles-to-monitor-physical-activity-of-participants-with-or-without-a-neurological-disorder
#6
Katie Gant, Jorge Bohorquez, Christine K Thomas
Various portable monitors have been used to quantify physical activity but most rely on detecting limb movement with a sensor rather than measuring muscle activity. Our first goal was to design and validate a portable system for recording surface electromyographic activity (EMG) from eight muscles over 24 h. The modular system includes: (1) preamplifiers that filter and amplify signals; (2) a preprocessor unit for further filtering and amplification, signal offset and power supply modification; (3) a data-logger for analog-to-digital conversion; a flash memory card for data storage and (4) a rechargeable battery...
November 2, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/29076061/decreased-neuron-number-and-synaptic-plasticity-in-sirt3-knockout-mice-with-poor-remote-memory
#7
Hyopil Kim, Somi Kim, Ja Eun Choi, DaeHee Han, Soo Min Koh, Hyun-Seok Kim, Bong-Kiun Kaang
The sirtuin family of proteins consists of nicotinamide adenine dinucleotide-dependent deacetylases that are involved in the response to calorie restriction and various physiological phenomena, such as aging and cognition. One of these proteins, sirtuin 3 (SIRT3), is localized in the mitochondria and protects the cell against oxidative or metabolic stress. Sirtuin protein deficiencies have been shown to accelerate neurodegeneration in neurotoxic conditions. The mechanisms underlying the involvement of SIRT3 in cognition remain unclear...
October 26, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/29065315/switching-memory-perspective
#8
Shazia Akhtar, Lucy V Justice, Catherine Loveday, Martin A Conway
The perspective in which memories were spontaneously recalled, field (original perspective) or observer (see oneself in the memory), was examined for both recent and remote memories. Recent memories were dominated by field perspective whilst remote memories were dominated by observer perspective. Further, field memories contained reliably more episodic detail than observer memories. After a 1-week interval, the same memories were recalled again but with a switched memory perspective. Switching from an observer to a field perspective did not reliably increase the amount of episodic details in a memory...
October 21, 2017: Consciousness and Cognition
https://www.readbyqxmd.com/read/29058940/much-ado-about-aha-insight-problem-solving-is-strongly-related-to-working-memory-capacity-and-reasoning-ability
#9
Adam Chuderski, Jan Jastrzębski
A battery comprising 4 fluid reasoning tests as well as 13 working memory (WM) tasks that involved storage, recall, updating, binding, and executive control, was applied to 318 adults in order to evaluate the true relationship of reasoning ability and WM capacity (WMC) to insight problem solving, measured using 40 verbal, spatial, math, matchstick, and remote associates problems (insight problems). WMC predicted 51.8% of variance in insight problem solving and virtually explained its almost isomorphic link to reasoning ability (84...
October 23, 2017: Journal of Experimental Psychology. General
https://www.readbyqxmd.com/read/29057735/association-between-chronic-kidney-disease-and-the-cognitive-function-in-subjects-without-overt-dementia%C3%A2
#10
Hiroyuki Ito, Shinichi Antoku, Toshiko Mori, Yoshitaka Nakagawa, Katsumi Mizoguchi, Suzuko Matsumoto, Takashi Omoto, Masahiro Shinozaki, Shinya Nishio, Mariko Abe, Mizuo Mifune, Michiko Togane
AIM: The association between cognitive function and clinical parameters of chronic kidney disease (CKD) was investigated in Japanese patients without overt dementia in a cross-sectional study. MATERIALS AND METHODS: A population of 497 patients whose cognitive function had been examined using the mini-mental state examination (MMSE) were screened for this study. After the exclusion of 306 subjects who showed overt dementia, the association between the MMSE score and clinical characteristics was investigated in 191 subjects (male: 55%, age: 69 ± 12 years)...
October 23, 2017: Clinical Nephrology
https://www.readbyqxmd.com/read/29046560/ecosystem-functioning-is-enveloped-by-hydrometeorological-variability
#11
Christoforos Pappas, Miguel D Mahecha, David C Frank, Flurin Babst, Demetris Koutsoyiannis
Terrestrial ecosystem processes, and the associated vegetation carbon dynamics, respond differently to hydrometeorological variability across timescales, and so does our scientific understanding of the underlying mechanisms. Long-term variability of the terrestrial carbon cycle is not yet well constrained and the resulting climate-biosphere feedbacks are highly uncertain. Here we present a comprehensive overview of hydrometeorological and ecosystem variability from hourly to decadal timescales integrating multiple in situ and remote-sensing datasets characterizing extra-tropical forest sites...
September 2017: Nature ecology & evolution
https://www.readbyqxmd.com/read/29038217/hippocampal-area-ca1-and-remote-memory-in-rats
#12
Amber C Ocampo, Larry R Squire, Robert E Clark
Hippocampal lesions often produce temporally graded retrograde amnesia (TGRA), whereby recent memory is impaired more than remote memory. This finding has provided support for the process of systems consolidation. However, temporally graded memory impairment has not been observed with the watermaze task, and the findings have been inconsistent with context fear conditioning. One possibility is that large hippocampal lesions indirectly disrupt (by retrograde degeneration) the function of areas that project to the hippocampus that are important for task performance or thought to be important for storing consolidated memories...
November 2017: Learning & Memory
https://www.readbyqxmd.com/read/29030298/linking-muscarinic-receptor-activation-to-ups-mediated-object-memory-destabilization-implications-for-long-term-memory-modification-and-storage
#13
Mikaela L Stiver, Jacob M Cloke, Natalie Nightingale, Julian Rizos, William S Messer, Boyer D Winters
Consolidated memories can become destabilized during reactivation, resulting in a transient state of instability, a process that has been hypothesized to underlie long-term memory updating. Consistent with this notion, relatively remote memories, which are resistant to standard destabilization procedures, are reliably destabilized when novel information (i.e., the opportunity for memory updating) is present during reactivation. We have also shown that cholinergic muscarinic receptor (mAChR) activation can similarly destabilize consolidated object memories...
October 10, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/29020188/human-cytomegalovirus-specific-memory-cd4-t-cell-response-and-its-correlation-with-virus-transmission-to-the-fetus-in-pregnant-women-with-primary-infection
#14
Chiara Fornara, Irene Cassaniti, Maurizio Zavattoni, Milena Furione, Kodjo M G Adzasehoun, Annalisa De Silvestri, Giuditta Comolli, Fausto Baldanti
Background: Primary human cytomegalovirus (HCMV) infection during pregnancy is the major cause of congenital viral sequelae. The HCMV-specific T-cell response may have a role in the prevention of virus transmission to the fetus. Methods: HCMV-specific memory T cells were investigated in the second month after primary infection onset in 44 pregnant women (15 transmitting the infection to the fetus) and 8 pregnant women with remote infection. Peripheral blood mononuclear cells were stimulated for 12 days with peptide pools of HCMV proteins IE-1, IE-2, and pp65, and subsequently restimulated for 24 hours with the same peptide pools in a cultured enzyme-linked immunospot (ELISPOT) assay...
July 20, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29020066/characteristics-of-the-memory-sources-of-dreams-a-new-version-of-the-content-matching-paradigm-to-take-mundane-and-remote-memories-into-account
#15
Raphael Vallat, Benoit Chatard, Mark Blagrove, Perrine Ruby
Several studies have demonstrated that dream content is related to the waking life of the dreamer. However, the characteristics of the memory sources incorporated into dreams are still unclear. We designed a new protocol to investigate remote memories and memories of trivial experiences, both relatively unexplored in dream content until now. Upon awakening, for 7 days, participants identified the waking life elements (WLEs) related to their dream content and characterized them and their dream content on several scales to assess notably emotional valence...
2017: PloS One
https://www.readbyqxmd.com/read/29017445/protein-remote-homology-detection-based-on-bidirectional-long-short-term-memory
#16
Shumin Li, Junjie Chen, Bin Liu
BACKGROUND: Protein remote homology detection plays a vital role in studies of protein structures and functions. Almost all of the traditional machine leaning methods require fixed length features to represent the protein sequences. However, it is never an easy task to extract the discriminative features with limited knowledge of proteins. On the other hand, deep learning technique has demonstrated its advantage in automatically learning representations. It is worthwhile to explore the applications of deep learning techniques to the protein remote homology detection...
October 10, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28978234/the-hippocampus-and-amygdala-are-integrators-of-neocortical-influence-a-cortico-cortical-evoked-potential-study
#17
Pierre Mégevand, David M Groppe, Stephan Bickel, Manuel R Mercier, Matthew S Goldfinger, Corey J Keller, Laszlo Entz, Ashesh D Mehta
Brain stimulation is increasingly viewed as an effective approach to treat neuropsychiatric disease. The brain's organization in distributed networks suggests that the activity of a remote brain structure could be modulated by stimulating cortical areas that strongly connect to the target. Most connections between cerebral areas are asymmetric, and a better understanding of the relative direction of information flow along connections could improve the targeting of stimulation to influence deep brain structures...
October 5, 2017: Brain Connectivity
https://www.readbyqxmd.com/read/28975787/high-performance-single-active-layer-memristor-based-on-an-ultrananocrystalline-oxygen-deficient-tiox-film
#18
Saurabh Srivastava, Joseph P Thomas, Nina F Heinig, K T Leung
The theoretical and practical realization of memristive devices has been hailed as the next step for nonvolatile memories, low-power remote sensing, and adaptive intelligent prototypes for neuromorphic and biological systems. However, the active materials of currently available memristors need to undergo an often destructive high-bias electroforming process in order to activate resistive switching. This limits their device performance in switching speed, endurance/retention, and power consumption upon high-density integration, due to excessive Joule heating...
October 16, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28966835/robotic-telecytology-for-remote-cytologic-evaluation-without-an-on-site-cytotechnologist-or-cytopathologist-an-active-quality-assessment-and-experience-of-over-400-cases
#19
Sahussapont Joseph Sirintrapun, Dorota Rudomina, Allix Mazzella, Rusmir Feratovic, William Alago, Robert Siegelbaum, Oscar Lin
BACKGROUND: The first satellite center to offer interventional radiology procedures at Memorial Sloan Kettering Cancer Center opened in October 2014. Two of the procedures offered, fine needle aspirations and core biopsies, required a rapid on-site cytologic evaluation of smears and biopsy touch imprints for cellular content and adequacy. The volume and frequency of such evaluations did not justify hiring on-site cytotechnologists, and therefore, a dynamic robotic telecytology (TC) solution was created...
2017: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/28966832/robotic-telecytology-for-remote-cytologic-evaluation-without-an-on-site-cytotechnologist-or-cytopathologist-a-tale-of-implementation-and-review-of-constraints
#20
Sahussapont Joseph Sirintrapun, Dorota Rudomina, Allix Mazzella, Rusmir Feratovic, William Alago, Robert Siegelbaum, Oscar Lin
BACKGROUND: The first satellite center to offer interventional radiology procedures at Memorial Sloan Kettering Cancer Center opened in October 2014. Two of the procedures offered, fine needle aspirations and core biopsies, required rapid on-site cytologic evaluation of smears and biopsy touch imprints for cellular content and adequacy. The volume and frequency of such evaluations did not justify hiring on-site cytotechnologists, and therefore, a dynamic robotic telecytology (TC) solution was created...
2017: Journal of Pathology Informatics
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