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Remote Memory

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https://www.readbyqxmd.com/read/29780861/the-relationship-between-recall-of-recently-versus-remotely-encoded-famous-faces-and-amyloidosis-in-clinically-normal-older-adults
#1
Irina Orlovsky, Willem Huijbers, Bernard J Hanseeuw, Elizabeth C Mormino, Trey Hedden, Rachel F Buckley, Molly LaPoint, Jennifer S Rabin, Dorene M Rentz, Keith A Johnson, Reisa A Sperling, Kathryn V Papp
Introduction: Alzheimer's disease (AD) patients exhibit temporally graded memory loss with remote memories remaining more intact than recent memories. It is unclear whether this temporal pattern is observable in clinically normal adults with amyloid pathology (i.e. preclinical AD). Methods: Participants were asked to recall the names of famous figures most prominent recently (famous after 1990) and remotely (famous from 1960-1980) and were provided with a phonemic cue to ensure that memory failure was not purely due to verbal retrieval weaknesses...
2018: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
https://www.readbyqxmd.com/read/29776994/first-demonstration-of-olfactory-learning-and-long-term-memory-in-honey-bee-queens
#2
Zhiwen Gong, Ken Tan, James C Nieh
As the primary source of colony reproduction, social insect queens play a vital role. However, the cognitive abilities of queens are not well understood, although queen learning and memory are essential in multiple species such as honey bees, in which virgin queens must leave the nest and then successful learn to navigate back over repeated nuptial flights. Honey bee queen learning has never been previously demonstrated. We therefore tested olfactory learning in queens and workers and examined the role of DNA methylation, which plays a key role in long term memory formation...
May 18, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29773974/orexin-a-differentially-influences-the-extinction-retention-of-recent-and-remote-fear-memory
#3
Le Shi, Wenhao Chen, Jiahui Deng, Sijing Chen, Ying Han, Muhammad Z Khan, Jiajia Liu, Jianyu Que, Yanping Bao, Lin Lu, Jie Shi
Recently the role of the orexin system in the learning and memory, especially orexin A, which could enhance fear memory through regulating the activity of amygdala, has drawn considerable attention. However, the relationship between orexin A and extinction memory remains unclear. To investigate the effect of orexin A on extinction memory in humans, we recruited 43 male subjects and divided them into a recent group and remote group. After acquiring Pavlovian fear conditioning, individuals in recent group experienced fear extinction 24 h after acquisition, and remote group underwent extinction 2 weeks later...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29747244/nucleus-reuniens-of-the-thalamus-controls-fear-memory-intensity-specificity-and-long-term-maintenance-during-consolidation
#4
Fernanda Troyner, Maira A Bicca, Leandro J Bertoglio
The thalamic nucleus reuniens (NR) has been shown to support bidirectional medial prefrontal cortex-hippocampus communication and synchronization relevant for cognitive processing. Using non-selective or prolonged inactivation of the NR, previous studies reported its activity positively modulates aversive memory consolidation. Here we examined the NR's role in consolidating contextual fear memories with varied strength, at both recent and more remote time points, using muscimol-induced temporary inactivation in rats...
May 10, 2018: Hippocampus
https://www.readbyqxmd.com/read/29743496/complex-housing-causes-a-robust-increase-in-dendritic-complexity-and-spine-density-of-medial-prefrontal-cortical-neurons
#5
Archana Ashokan, Jamien Wee Han Lim, Nicholas Hang, Rupshi Mitra
Prelimbic cortex and infralimbic cortex, parts of the ventromedial prefrontal cortex, are critical brain regions for generating a flexible behavioral response to changing environmental contingencies. This includes the role of these brain structures in the extinction of learned fear, decision making and retrieval of remote memories. Dendritic structure of medial prefrontal cortex neurons retains significant structural plasticity in adulthood. This has been mainly demonstrated as dendritic atrophy and loss of dendritic spines due to chronic stress...
May 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29740084/periodical-reactivation-under-the-effect-of-caffeine-attenuates-fear-memory-expression-in-rats
#6
Lizeth K Pedraza, Rodrigo O Sierra, Fernanda N Lotz, Lucas de Oliveira Alvares
In the last decade, several studies have shown that fear memories can be attenuated by interfering with reconsolidation. However, most of the pharmacological agents used in preclinical studies cannot be administered to humans. Caffeine is one of the world's most popular psychoactive drugs and its effects on cognitive and mood states are well documented. Nevertheless, the influence of caffeine administration on fear memory processing is not as clear. We employed contextual fear conditioning in rats and acute caffeine administration under a standard memory reconsolidation protocol or periodical memory reactivation...
May 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29724228/randomized-control-trial-of-computer-based-training-targeting-alertness-in-older-adults-the-alert-trial-protocol
#7
Thomas VanVleet, Michelle Voss, Sawsan Dabit, Alex Mitko, Joseph DeGutis
BACKGROUND: Healthy aging is associated with a decline in multiple functional domains including perception, attention, short and long-term memory, reasoning, decision-making, as well as cognitive and motor control functions; all of which are significantly modulated by an individual's level of alertness. The control of alertness also significantly declines with age and contributes to increased lapses of attention in everyday life, ranging from minor memory slips to a lack of vigilance and increased risk of falls or motor-vehicle accidents...
May 3, 2018: BMC Psychology
https://www.readbyqxmd.com/read/29723709/aiding-the-search-examining-individual-differences-in-multiply-constrained-problem-solving
#8
Derek M Ellis, Gene A Brewer
Understanding and resolving complex problems is of vital importance in daily life. Problems can be defined by the limitations they place on the problem solver. Multiply-constrained problems are traditionally examined with the compound remote associates task (CRAT). Performance on the CRAT is partially dependent on an individual's working memory capacity (WMC). These findings suggest that executive processes are critical for problem solving and that there are reliable individual differences in multiply-constrained problem solving abilities...
April 27, 2018: Consciousness and Cognition
https://www.readbyqxmd.com/read/29712785/remote-memory-and-cortical-synaptic-plasticity-require-neuronal-ccctc-binding-factor-ctcf
#9
Somi Kim, Nam-Kyung Yu, Kyu-Won Shim, Ji-Il Kim, Hyopil Kim, Dae Hee Han, Ja Eun Choi, Seung-Woo Lee, Dong Il Choi, Myung Won Kim, Dong-Sung Lee, Kyungmin Lee, Niels Galjart, Yong-Seok Lee, Jae-Hyung Lee, Bong-Kiun Kaang
The molecular mechanism of long-term memory has been extensively studied in the context of the hippocampus-dependent recent memory examined within several days. However, months-old remote memory maintained in the cortex for long-term has not been investigated much at the molecular level yet. Various epigenetic mechanisms are known to be important for long-term memory, but how the three-dimensional (3D) chromatin architecture and its regulator molecules contribute to neuronal plasticity and systems consolidation are still largely unknown...
April 30, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29698768/is-working-memory-stored-along-a-logarithmic-timeline-converging-evidence-from-neuroscience-behavior-and-models
#10
Inder Singh, Zoran Tiganj, Marc W Howard
A growing body of evidence suggests that short-term memory does not only store the identity of recently experienced stimuli, but also information about when they were presented. This representation of 'what' happened 'when' constitutes a neural timeline of recent past. Behavioral results suggest that people can sequentially access memories for the recent past, as if they were stored along a timeline to which attention is sequentially directed. In the short-term judgment of recency (JOR) task, the time to choose between two probe items depends on the recency of the more recent probe but not on the recency of the more remote probe...
April 23, 2018: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/29695844/remote-quantum-entanglement-between-two-micromechanical-oscillators
#11
Ralf Riedinger, Andreas Wallucks, Igor Marinković, Clemens Löschnauer, Markus Aspelmeyer, Sungkun Hong, Simon Gröblacher
Entanglement, an essential feature of quantum theory that allows for inseparable quantum correlations to be shared between distant parties, is a crucial resource for quantum networks 1 . Of particular importance is the ability to distribute entanglement between remote objects that can also serve as quantum memories. This has been previously realized using systems such as warm2,3 and cold atomic vapours4,5 , individual atoms 6 and ions7,8 , and defects in solid-state systems9-11 . Practical communication applications require a combination of several advantageous features, such as a particular operating wavelength, high bandwidth and long memory lifetimes...
April 2018: Nature
https://www.readbyqxmd.com/read/29693311/external-details-revisited-a-new-taxonomy-for-coding-non-episodic-content-during-autobiographical-memory-retrieval
#12
Cherie Strikwerda-Brown, Annu Mothakunnel, John R Hodges, Olivier Piguet, Muireann Irish
Autobiographical memory (ABM) is typically held to comprise episodic and semantic elements, with the vast majority of studies to date focusing on profiles of episodic details in health and disease. In this context, 'non-episodic' elements are often considered to reflect semantic processing or are discounted from analyses entirely. Mounting evidence suggests that rather than reflecting one unitary entity, semantic autobiographical information may contain discrete subcomponents, which vary in their relative degree of semantic or episodic content...
April 24, 2018: Journal of Neuropsychology
https://www.readbyqxmd.com/read/29686631/the-perception-of-time-is-underestimated-in-adolescents-with-anorexia-nervosa
#13
Carmelo M Vicario, Kim Felmingham
Research has revealed reduced temporal discounting (i.e., increased capacity to delay reward) and altered interoceptive awareness in anorexia nervosa (AN). In line with the research linking temporal underestimation with a reduced tendency to devalue a reward and reduced interoceptive awareness, we tested the hypothesis that time duration might be underestimated in AN. Our findings revealed that patients with AN displayed lower timing accuracy in the form of timing underestimation compared with controls. These results were not predicted by clinical, demographic factors, attention, and working memory performance of the participants...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29643700/evaluation-of-the-accuracy-of-ecg-captured-by-cardiochip-through-comparison-of-lead-i-recording-to-a-standard-12-lead-ecg-recording-device
#14
Chi-In Lo, Sheng-Shiung Chang, Jui-Peng Tsai, Jen-Yuan Kuo, Ying-Ju Chen, Ming-Yuan Huang, Chao-Hsiung Lee, Kuo-Tzu Sung, Chung-Lieh Hung, Charles Jia-Yin Hou, Edward Lai, Hung-I Yeh, Wen-Ling Chang, Wen-Han Chang
Background: Remote cardiac rhythm monitoring and recording, using hand-carried electrocardiogram (ECG) device had been widely used in telemedicine. The feasibility and accuracy analysis on the data recorded by a new miniature ECG system-on-chip (SoC) system has not been explored before. Methods: This study evaluated the accuracy of the ECG recordings captured by CardioChip - a single-channeled, low-powered, miniature ECG SoC designed for mobile applications; comparing against Philips Pagewriter Trim III - a Food and Drug Administration certified, widely-used standard 12-lead ECG recording device, within Mackay Memorial Hospital in Taiwan...
March 2018: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/29603458/automated-calibration-of-laser-spectrometer-measurements-of-%C3%AE-18-o-and-%C3%AE-2-h-values-in-water-vapour-using-a-dew-point-generator
#15
Niels C Munksgaard, Alexander W Cheesman, Andrew Gray-Spence, Lucas A Cernusak, Michael I Bird
RATIONALE: Continuous measurement of stable O and H isotope compositions in water vapour requires automated calibration for remote field deployments. We developed a new low-cost device for calibration of both water vapour mole fraction and isotope composition. METHODS: We coupled a commercially available dew point generator (DPG) to a laser spectrometer and developed hardware for water and air handling along with software for automated operation and data processing...
March 30, 2018: Rapid Communications in Mass Spectrometry: RCM
https://www.readbyqxmd.com/read/29597013/a-new-telemetry-based-system-for-assessing-cardiovascular-function-in-group-housed-large-animals-taking-the-3rs-to-a-new-level-with-the-evaluation-of-remote-measurement-via-cloud-data-transmission
#16
Michael Markert, Thomas Trautmann, Florian Krause, Marius Cioaga, Sebastien Mouriot, Miriam Wetzel, Brian D Guth
INTRODUCTION: A newly developed total implant telemetry system for cardiovascular (CV), electrophysiological and body temperature measurement was evaluated. A cloud-based transmission of the physiological signals allowed an assessment of the quality of the physiological signals despite the physical separation between the instrumented animals and the evaluating home laboratory. The new system is intended to be used for safety pharmacological evaluations of drug candidates in various species...
March 26, 2018: Journal of Pharmacological and Toxicological Methods
https://www.readbyqxmd.com/read/29588954/frequent-sleep-related-bitemporal-focal-seizures-in-transient-epileptic-amnesia-syndrome-evidence-from-ictal-video-eeg
#17
David B Burkholder, Amy L Jones, David T Jones, Rachel R Fabris, Jeffrey W Britton, Terrence D Lagerlund, Elson L So, Gregory D Cascino, Gregory A Worrell, Cheolsu Shin, Erik K St Louis
Two patients who shared similar presenting clinical features of anterograde and retrograde autobiographical amnesia typical of transient epileptic amnesia (TEA) underwent prolonged video electroencephalogram (VEEG) monitoring and were found to have sleep-activated epileptiform activity and frequent subclinical bitemporal seizures predominantly during sleep. Case 1 is a 59-year-old woman whose presenting complaint was memory impairment. Over 18 months, she had three distinct 8-h-long episodes of confusion and disorientation with persistent anterograde and retrograde autobiographical amnesia...
June 2017: Epilepsia Open
https://www.readbyqxmd.com/read/29572461/dnmt3a-in-the-dorsal-dentate-gyrus-is-a-key-regulator-of-fear-renewal
#18
Zhiting Gong, Qiang Zhou
Renewal of extinguished fear memory in an altered context is widely believed to be a major limiting issue for exposure therapy in treating various psychiatric diseases. Effective prevention of fear renewal will significantly improve the efficacy of exposure therapy. DNA methyltransferase (DNMTs) mediated epigenetic processes play critical roles in long term memory, but little is known about their functions in fear memory extinction or renewal. Here we investigated whether DNMTs regulate fear renewal after extinction...
March 23, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29548259/does-rural-generalist-focused-medical-school-and-family-medicine-training-make-a-difference-memorial-university-of-newfoundland-outcomes
#19
James Rourke, Shabnam Asghari, Oliver Hurley, Mohamed Ravalia, Michael Jong, Wendy Graham, Wanda Parsons, Norah Duggan, Danielle O'Keefe, Scott Moffatt, Katherine Stringer, Carolyn Sturge Sparkes, Janelle Hippe, Kristin Harris Walsh, Donald McKay, Asoka Samarasena
INTRODUCTION: Rural recruitment and retention of physicians is a global issue. The Faculty of Medicine at Memorial University of Newfoundland, Canada, was established as a rural-focused medical school with a social accountability mandate that aimed to meet the healthcare needs of a sparse population distributed over a large landmass as well as the needs of other rural and remote areas of Canada. This study aimed to assess whether Memorial medical degree (MD) and postgraduate (PG) programs were effective at producing physicians for their province and rural physicians for Canada compared with other Canadian medical schools...
March 2018: Rural and Remote Health
https://www.readbyqxmd.com/read/29548258/from-pipelines-to-pathways-the-memorial-experience-in-educating-doctors-for-rural-generalist-practice
#20
James Rourke, Shabnam Asghari, Oliver Hurley, Mohamed Ravalia, Michael Jong, Wanda Parsons, Norah Duggan, Katherine Stringer, Danielle O'Keefe, Scott Moffatt, Wendy Graham, Carolyn Sturge Sparkes, Janelle Hippe, Kristin Harris Walsh, Donald McKay, Asoka Samarasena
CONTEXT: This report describes the community context, concept and mission of The Faculty of Medicine at Memorial University of Newfoundland (Memorial), Canada, and its 'pathways to rural practice' approach, which includes influences at the pre-medical school, medical school experience, postgraduate residency training, and physician practice levels. Memorial's pathways to practice helped Memorial to fulfill its social accountability mandate to populate the province with highly skilled rural generalist practitioners...
March 2018: Rural and Remote Health
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