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ACL Repair

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https://www.readbyqxmd.com/read/29431515/different-expression-profiles-of-the-lysyl-oxidases-and-matrix-metalloproteinases-in-human-acl-fibroblasts-after-co-culture-with-synovial-cells
#1
Chunli Wang, Chunming Xu, Rongfu Chen, Li Yang, Kl Paul Sung
Purposes The anterior cruciate ligament (ACL) has poor functional healing response. The synovial tissue surrounding ACL ligament might be a major regulator of the microenvironment in the joint cavity after ACL injury, thus affecting the repair process. Using transwell co-culture, this study explored the direct influence of human synovial cells (HSCs) on ACL fibroblasts (ACLfs) by characterizing the differential expression of the lysyl oxidase family (LOXs) and matrix metalloproteinases (MMP-1, -2, -3), which facilitate extracellular matrix (ECM) repair and degradation, respectively...
February 12, 2018: Connective Tissue Research
https://www.readbyqxmd.com/read/29430501/modified-internal-fixation-technique-for-acromio-clavicular-ac-joint-dislocation-the-hidden-knot-technique
#2
Hamidreza Aslani, Fateme Mirzaee, Zohreh Zafarani, Shahin Salehi
Acromioclavicular (AC) joint injuries are common and often seen in contact athletes, resulting from a fall on the shoulder tip with adducted arm. This joint is stabilized by both static and dynamic structures including the coracoclavicular (CC) ligament. Most reconstruction techniques focus on CC ligament augmentation as the primary stabilizer of the AC joint. The best surgical technique for some AC joint dislocations is still controversial. In this study, we explained a modification of the CC ligament reconstruction technique described by Wellmann...
January 2018: Archives of Bone and Joint Surgery
https://www.readbyqxmd.com/read/29421350/long-term-evaluation-of-osteoarthritis-sheep-knee-treated-with-tgf-%C3%AE-3-and-bmp-6-induced-multipotent-stem-cells
#3
C C Ude, B S Shamsul, M H Ng, H C Chen, Htwe Ohnmar, S N Amaramalar, A R Rizal, A Johan, M Y Norhamdan, M Azizi, B S Aminuddin, B H I Ruszymah
BACKGROUND: Hyaline articular cartilage, which protects the bones of diarthrodial joints from forces associated with load bearing, frictions, and impacts has very limited capacities for self-repair. Over the years, the trend of treatments has shifted to regenerations and researchers have been on the quest for a lasting regeneration. We evaluated the treatment of osteoarthritis by chondrogenically induced ADSCs and BMSCs for a long time functional recovery. METHODS: Osteoarthritis was induced at the right knee of sheep by complete resection of ACL and medial meniscus...
January 29, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29396585/dynamic-augmentation-restores-anterior-tibial-translation-in-acl-suture-repair-a-biomechanical-comparison-of-non-static-and-dynamic-augmentation-techniques
#4
Roy A G Hoogeslag, Reinoud W Brouwer, Rianne Huis In 't Veld, Joanna M Stephen, Andrew A Amis
PURPOSE: There is a lack of objective evidence investigating how previous non-augmented ACL suture repair techniques and contemporary augmentation techniques in ACL suture repair restrain anterior tibial translation (ATT) across the arc of flexion, and after cyclic loading of the knee. The purpose of this work was to test the null hypotheses that there would be no statistically significant difference in ATT after non-, static- and dynamic-augmented ACL suture repair, and they will not restore ATT to normal values across the arc of flexion of the knee after cyclic loading...
February 3, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29395746/reinterventions-after-dynamic-intraligamentary-stabilization-in-primary-anterior-cruciate-ligament-repair
#5
Janosch Häberli, Laurenz Jaberg, Kathrin Bieri, Stefan Eggli, Philipp Henle
BACKGROUND: The goal of this study was to perform an in-depth analysis of the frequency and cause of secondary interventions subsequent to primary anterior cruciate ligament (ACL) repair with dynamic intraligamentary stabilization (DIS). METHODS: Between July 2009 and June 2014, 455 patients underwent DIS treatment. The minimum follow-up was 21months (mean 28months, range 21-64months). RESULTS: A total of 215 (48.2%) reinterventions were performed in 190 (42...
January 29, 2018: Knee
https://www.readbyqxmd.com/read/29373290/clinical-outcomes-of-arthroscopic-primary-repair-of-proximal-anterior-cruciate-ligament-tears-are-maintained-at-midterm-follow-up
#6
Gregory S DiFelice, Jelle P van der List
PURPOSE: To assess the midterm clinical outcomes in patients with proximal avulsion anterior cruciate ligament (ACL) tears undergoing arthroscopic primary repair with suture anchors. METHODS: The first 11 consecutive patients with proximal avulsion tears treated with arthroscopic primary repair were evaluated at midterm (minimum 5-year) follow-up. Physical examination was performed; laxity examination consisting of the Lachman, pivot-shift, and anterior drawer tests was performed; and patients were asked to complete the Lysholm, modified Cincinnati, Single Assessment Numeric Evaluation, and International Knee Documentation Committee (IKDC) questionnaires...
January 16, 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29354469/arthroscopic-primary-anterior-cruciate-ligament-repair-with-suture-augmentation
#7
Jelle P van der List, Gregory S DiFelice
Historically, poor results of open primary repair of anterior cruciate ligament (ACL) injuries have been reported. In hindsight, however, appropriate patient selection (i.e. proximal tears and good tissue quality) was not performed, because it has recently been recognized that good outcomes of primary ACL repair are possible when selectively performed in patients with proximal tears and good tissue quality. Moreover, with modern-day advances, arthroscopic primary repair can be an excellent treatment option for patients with proximal tears...
October 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/29354428/tibial-eminence-fracture-repair-with-double-hewson-suture-passer-technique
#8
Steven F DeFroda, Jonathan D Hodax, Kalpit N Shah, Aristides I Cruz
Displaced tibial eminence fractures are commonly encountered in pediatric patients and are often considered to be functionally equivalent to an anterior cruciate ligament (ACL) rupture. While a variety of techniques are available for fixation of this injury, we describe an anchorless technique relying on suture fixation tied over a bone bridge. This technique also relies on two intra-articular Hewson suture passers to quickly and effectively pass and shuttle sutures through the ACL and tibial bone tunnels in order to reduce and fix the fracture fragment...
August 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/29285553/arthroscopic-primary-repair-of-the-anterior-cruciate-ligament-what-the-radiologist-needs-to-know
#9
REVIEW
Steven P Daniels, Jelle P van der List, J Jacob Kazam, Gregory S DiFelice
Recently, there has been a renewed interest in primary repair of proximal anterior cruciate ligament (ACL) tears. Magnetic resonance imaging (MRI) plays an important role in preoperative patient selection and in postoperative ligament assessment. Knowledge of the imaging factors that make patients candidates for primary ACL repair, namely proximal tear location and good tissue quality, can help radiologists provide information that is meaningful for surgical decision making. Furthermore, an understanding of the surgical techniques can prevent misinterpretation of the postoperative MRI...
December 28, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/29284175/surgical-management-of-simultaneous-anterior-cruciate-ligament-and-patellar-tendon-ruptures-a-systematic-review
#10
Carlos J Meheux, Robert A Jack, Patrick C McCulloch, David M Lintner, Joshua D Harris
This study performs a systematic review to determine (1) if a significant difference exists in return to preinjury activity level between one- and two-stage treatment of combined anterior cruciate ligament (ACL) and patellar tendon (PT) tears; and (2) if a significant difference exists in the number of postoperative complications between the two differing surgical treatment approaches. A systematic review was performed using Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines and registered on PROSPERO...
December 28, 2017: Journal of Knee Surgery
https://www.readbyqxmd.com/read/29227559/magnetic-resonance-measurements-of-tissue-quantity-and-quality-using-t2-relaxometry-predict-temporal-changes-in-the-biomechanical-properties-of-the-healing-acl
#11
Jillian E Beveridge, Jason T Machan, Edward G Walsh, Ata M Kiapour, N Padmini Karamchedu, Kaitlyn E Chin, Benedikt L Proffen, Jakob T Sieker, Martha M Murray, Braden C Fleming
The purpose of this study was to develop a magnetic resonance T2 * relaxometry-based multiple linear regression model to predict the structural properties of the healing anterior cruciate ligament (ACL) over a 24-week healing period following ACL repair in Yucatan minipigs. Two hypotheses were tested: (1) that a regression model based on ACL sub-volumes containing short and long T2 * relaxation times would outperform a competing model based on sub-volumes of short T2 * relaxation times only; and (2) that an optimized regression model would be capable of predicting ACL structural properties between 6 and 24 weeks post-repair...
December 11, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29181251/lower-extremity-kinematics-of-acl-repaired-and-non-injured-females-when-using-knee-savers%C3%A2
#12
Whitley J Stone, Scott W Arnett, Donald L Hoover
Background: Knee Savers® (KS) are an ergonomic aid purported to lessen the risk of injuries linked to deep squats. While widely used in sports such as baseball and softball, KS have not been tested to determine their effect upon lower extremity kinematics in any population. Purpose: The purpose of the study was to determine if KS influenced the lower extremity kinematics when females with previous anterior cruciate ligament (ACL)-reconstruction and healthy participants completed an end-range squat...
October 2017: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/29162378/arthroscopic-medial-meniscal-repair-with-or-without-concurrent-anterior-cruciate-ligament-reconstruction-a-subgroup-analysis
#13
Erdal Uzun, Abdulhamit Misir, Turan Bilge Kizkapan, Mustafa Ozcamdalli, Soner Akkurt, Ahmet Guney
BACKGROUND: There are few large-scale, long-term studies comparing medial meniscal repairs with or without concurrent anterior cruciate ligament (ACL) reconstruction. METHODS: A total of 140 patients who underwent arthroscopic medial meniscal repair were divided into two groups: Group A, meniscus repair only and Group B, meniscus repair with concurrent ACL reconstruction. Clinical assessments in- cluded physical examination findings, Lysholm score, and the International Knee Documentation Committee (IKDC) form...
November 18, 2017: Knee
https://www.readbyqxmd.com/read/29149846/the-impact-of-bone-morphology-on-the-outcome-of-the-pivot-shift-test-a-cohort-study
#14
Thomas Branch, Shaun Stinton, Adrija Sharma, Frederic Lavoie, Christian Guier, Philippe Neyret
BACKGROUND: The presence of a positive pivot shift after surgical repair of the ACL is considered an important indicator of a failed reconstruction. The ability to predict the result of a pivot shift test after an ACL reconstruction using variables that can be measured prior to surgery could provide an indication of which patients may be at-risk of a poor surgical outcome.The purpose of this study was to determine whether structural characteristics of the femur and tibia, measured using plain radiographs, were associated with the result of the pivot shift test in unilateral ACL reconstructed patients...
November 17, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29134251/meniscal-repair-results-in-inferior-short-term-outcomes-compared-with-meniscal-resection-a-cohort-study-of-6398-patients-with-primary-anterior-cruciate-ligament-reconstruction
#15
Eleonor Svantesson, Riccardo Cristiani, Eric Hamrin Senorski, Magnus Forssblad, Kristian Samuelsson, Anders Stålman
PURPOSE: To compare patient reported outcome measures (PROMs) during the first postoperative year between isolated anterior cruciate ligament (ACL) reconstruction and ACL reconstruction with concomitant meniscal intervention. METHODS: Patients who underwent primary ACL reconstruction at Capio Artro Clinic, Stockholm, Sweden, between 1st Jan 2001 and 31st Dec 2014 without concomitant injuries others than meniscal and/or cartilage lesions were included. Five groups of meniscal treatment simultaneously to ACL reconstruction were established; medial meniscal (MM) resection, MM repair, lateral meniscal (LM) resection, LM repair, and MM + LM resection...
November 13, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29132386/primary-single-suture-anchor-re-fixation-of-anterior-cruciate-ligament-proximal-avulsion-tears-leads-to-good-functional-mid-term-results-a-preliminary-study-in-12-patients
#16
Christof Hoffmann, Jan Friederichs, Christian von Rüden, Christian Schaller, Volker Bühren, Christoph Moessmer
BACKGROUND: Current studies demonstrate encouraging short-term results after primary anterior cruciate ligament (ACL) suture anchor repair. However, earlier studies reported deterioration of knee function at 5-year follow-up following good clinical short-term recovery. Therefore, the aim of this study was to evaluate clinical long-term results after primary ACL repair at a minimum 5-year follow-up. METHODS: In a retrospective study, 13 patients were included between 2009 and 2012...
November 13, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29124289/peak-stresses-shift-from-femoral-tunnel-aperture-to-tibial-tunnel-aperture-in-lateral-tibial-tunnel-acl-reconstructions-a-3d-graft-bending-angle-measurement-and-finite-element-analysis
#17
Hans Van Der Bracht, Thomas Tampere, Pieter Beekman, Alexander Schepens, Wouter Devriendt, Peter Verdonk, Jan Victor
PURPOSE: To investigate the effect of tibial tunnel orientation on graft-bending angle and stress distribution in the ACL graft. METHODS: Eight cadaveric knees were scanned in extension, 45°, 90°, and full flexion. 3D reconstructions with anatomically placed anterior cruciate ligament (ACL) grafts were constructed with Mimics 14.12(®). 3D graft-bending angles were measured for classic medial tibial tunnels (MTT) and lateral tibial tunnels (LTT) with different drill-guide angles (DGA) (45°, 55°, 65°, and 75°)...
November 9, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29106758/transcriptomic-analysis-of-synovial-extracellular-rna-following-knee-trauma-a-pilot-study
#18
Anthony J Griswold, Jose Perez, Karen Nuytemans, Thomas Strong, Liyong Wang, Danica D Vance, Hayley Ennis, Marvin K Smith, Thomas M Best, Jeffery M Vance, Margaret A Pericak-Vance, Lee D Kaplan
Traumatic knee injuries often result in damage to articular cartilage and other joint structures. Such trauma is a strong risk factor for the future development and progression of osteoarthritis (OA). The molecular mechanisms and signaling pathways modulating response to knee joint trauma remain unclear. Moreover, investigations of biomarkers influencing responses have been targeted rather than broad, unbiased discovery studies. Herein we characterize the complete complement of extracellular RNA (exRNA) in the synovial fluid of 14 subjects following knee injury...
November 6, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29051899/surgical-treatment-of-segond-fractures-in-acute-anterior-cruciate-ligament-reconstruction
#19
Andrea Ferretti, Edoardo Monaco, Megan Rianne Wolf, Matteo Guzzini, Angelo De Carli, Daniele Mazza
BACKGROUND: The Segond fracture is an avulsion-type fracture located on the anterolateral aspect of the tibia associated with a ligament recently termed the anterolateral ligament. This injury has been described as pathognomonic for an anterior cruciate ligament (ACL) tear and is associated with a higher grade pivot shift. PURPOSE: To present and report 2-year clinical outcomes of a surgical technique for acute ACL reconstruction with fixation of a concomitant Segond fracture...
October 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29051896/outcomes-and-complication-rates-after-primary-anterior-cruciate-ligament-reconstruction-are-similar-in-younger-and-older-patients
#20
Mark E Cinque, Jorge Chahla, Gilbert Moatshe, Nicholas N DePhillipo, Nicholas I Kennedy, Jonathan A Godin, Robert F LaPrade
BACKGROUND: Until recently, anterior cruciate ligament (ACL) tears in older patients were treated conservatively; however, these patients often experienced significant pain and instability. PURPOSE/HYPOTHESIS: The purpose of this study was to compare the patient-reported outcomes, patient satisfaction, and failure rates of primary ACL reconstruction between a younger (age 20-30 years) and older (age 50-75 years) patient cohort. It was hypothesized that patients in the older cohort could achieve comparable clinical outcomes and retear rates following ACL reconstruction with a bone-tendon-bone autograft or allograft compared with the younger patients...
October 2017: Orthopaedic Journal of Sports Medicine
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