Uroliathiasis

OBJECTIVE: To explore the concentration changes of Tamm-Horsefall protein (THP) under centrifugation in rat urine and discuss its association with urolithiasis formation. METHODS: A total of 40 Wistar rats were divided randomly into 4 groups of flying with stone (A), flying without stone (B), stone without flying (C) and control (D). After centrifugation, the THP concentrations of each group were measured by enzyme-linked immunosorbent assay (ELISA). Then urinary system was dissected, stained with hematoxylin & eosin and observed under electron microscopy to examine the distribution and number of each section...

Spondylocarpotarsal synostosis syndrome (SSS) is an autosomal recessive condition which is characterized by short stature, a carpotarsal coalition and a vertebral fusion, but without any rib anomaly. We are presenting a 7- year- old boy, who had uroliathiasis with the spondylocarpotarsal synostosis syndrome. This association, to the best of our knowledge, has not been reported so far.

The present study was designed to evaluate the role of fluoride in urolithiasis in humans. Two areas were selected for this purpose, a fluoride endemic area (EA) and a fluoride non-endemic area (NEA). The prevalence of uroliathiasis was 4.6 times higher in EA than in NEA. Furthermore, the prevalence was almost double in subjects with fluorosis than without fluorosis in the endemic area. No relationship was observed between urolithiasis and the duration of fluorosis. The fluoride levels in drinking water ranged from 3...

A one-year material of 290 patients with clinically verified urolithiasis was screened for primary hyperparthyroidism, by X-ray examination, analysis of calculi, plasma calcium and phosphate, plasma parathyroid hormone and a clinical history examination. Primary hyperparathyroidism was found in 10 patients, 8 with adenomas and 2 with hyperplasia. The results suggest that with the present policy of investigation, there is a considerable underdiagnosis of parathyroid changes in patients with urolithiasis. An interesting finding was the distribution of plasma calcium concentrations in this material, which indicates that patients with urolithiasis have a generally higher lever of plasma calcium than others...