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https://www.readbyqxmd.com/read/29783014/comparison-of-micro-clamping-stent-retriever-thrombectomy-with-conventional-stent-retriever-thrombectomy-in-intracranial-large-vessel-embolism
#1
Zhen-Sheng Liu, Gang Deng, Long-Jiang Zhou, Yong Sun, Xin-Jiang Zhang, Xiong-Wei Kuang, Yong-Lin Qin, Jia-Xiang Wang, Qing Shan
OBJECTIVE: To evaluate the effectiveness of micro-clamping stent-retriever thrombectomy (MSRT) in acute ischemic stroke patients with intracranial large vessel embolism (ILVE), and compare the same with conventional stent-retriever thrombectomy (CSRT). MATERIALS AND METHODS: We retrospectively evaluated a total of 108 ILVE patients treated by MSRT (n=52) and CSRT (n=56) from the two participating institutions between January 2016 and November 2017. The rates of successful (mTICI 2b or 3) and complete reperfusion (mTICI 3), time from guide catheter placement to reperfusion, rates of first-pass success, and the number of passes for reperfusion were compared between the MSRT and CSRT groups...
May 18, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29783009/antiplatelet-medication-reversal-strategies-in-operative-intracranial-hemorrhage-a-survey-of-practicing-neurosurgeons
#2
Paul M Foreman, Adeel Ilyas, James Mooney, Philip G R Schmalz, Beverly C Walters, Christoph J Griessenauer
OBJECTIVE: Antiplatelet therapy is common and complicates the operative management of acute intracranial hemorrhage. Little data exist to guide antiplatelet reversal strategies. METHODS: An online survey detailing antiplatelet reversal strategies in patients presenting with acute operative intracranial hemorrhage (subdural hematoma (SDH), epidural hematoma (EDH), and intracerebral hemorrhage (ICH) was distributed to board certified neurosurgeons in the North America...
May 18, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29783007/intracranial-mesenchymal-chondrosarcoma-report-of-16-cases
#3
Xiujian Ma, Ke Wang, Teng-Xian Guo, Liang Wang, Da Li, Shu-Yu Hao, Gui-Jun Jia, Wang Jia, Jun-Ting Zhang, Li-Wei Zhang, Zhen Wu
OBJECTIVES: Limited data about intracranial mesenchymal chondrosarcoma (MCS) are available. The goal of this study was to report the clinical characteristics, challenges in management and poor outcomes of intracranial MCS. METHODS: Clinical data of 16 patients with MCS were reviewed retrospectively to evaluate their clinical characteristics, management and outcomes. RESULTS: This study included 11 male and 5 female patients with a mean age of 22...
May 18, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29782356/acute-neurologic-complications-during-extracorporeal-membrane-oxygenation-a-systematic-review
#4
Raoul Sutter, Kai Tisljar, Stephan Marsch
OBJECTIVES: We determine the frequency, risk factors, and mortality of neurologic complications in adults on extracorporeal membrane oxygenation and propose an algorithm for preventive strategies. DATA SOURCES: PubMed, Embase, and Cochrane databases. STUDY SELECTION: Screening was performed using predefined search terms to identify cohort studies reporting neurologic complications in adults during extracorporeal membrane oxygenation from 1990 to 2017...
May 18, 2018: Critical Care Medicine
https://www.readbyqxmd.com/read/29782307/cutaneous-manifestations-of-tuberous-sclerosis
#5
Mirjana Bakić, Marina Ratković, Branka Gledović, Balsa Vujović, Danilo Radunović, Vera Babić, Vladimir Prelević
Dear Editor, Tuberous sclerosis (TS) is an autosomal dominant multisystem disease, which occurs due to genetically determined hyperplasia of ectodermal and mesodermal cells. Clinical manifestations present on the skin and in the nervous system, kidneys, heart, and other organs. Recent studies estimate the incidence of TS at 1/6000 to 1/10,000 live births, and a prevalence in the general population of approximately 1 in 20,000 (1). There are two different genetic loci responsible for TS: 9q34 (TSC1-hamartin) and 16p13...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29782060/autosomal-dominant-early-onset-spastic-paraparesis-with-brain-calcification-due-to-ifih1-gain-of-function
#6
Lyse Ruaud, Gillian I Rice, Christelle Cabrol, Juliette Piard, Mathieu Rodero, Lien van Eyk, Elise Boucher-Brischoux, Alain Maertens de Noordhout, Ricardo Maré, Emmanuel Scalais, Fernand Pauly, François-Guillaume Debray, William Dobyns, Carolina Uggenti, Ji Woo Park, Sun Hur, John H Livingston, Yanick J Crow, Lionel Van Maldergem
We describe progressive spastic paraparesis in two male siblings and the daughter of one of these individuals. Onset of disease occurred within the first decade, with stiffness and gait difficulties. Brisk deep tendon reflexes and extensor plantar responses were present, in the absence of intellectual disability or dermatological manifestations. Cerebral imaging identified intracranial calcification in all symptomatic family members. A marked upregulation of interferon stimulated gene (ISG) transcripts was recorded in all three affected individuals and in two clinically unaffected relatives...
May 21, 2018: Human Mutation
https://www.readbyqxmd.com/read/29781742/early-prenatal-diagnosis-of-blakes-pouch-cyst-by-2d-3d-ultrasound-with-cristal-and-realistic-vue-application
#7
Gabriele Tonni, Gianpaolo Grisolia, Paolo Zampriolo, Edward Araujo Júnior, Rodrigo Ruano
INTRODUCTION: Blake's pouch cyst (BPC) represents an abnormal development of the posterior membranous area of the fetal brain. MATERIAL AND METHODS: Two- and three-dimensional ultrasound with Cristal and Realistic Vue were used to characterized the early prenatal diagnosis. RESULTS: At 9 weeks and 5 days a ballooning in the posterior fossa and resulting in an enlarged intracranial translucency (IT) was detected by 3D ultrasound using Cristal Vue in "inversion" mode and Cristal plus Realistic Vue...
May 21, 2018: Fetal and Pediatric Pathology
https://www.readbyqxmd.com/read/29781051/prehospital-prediction-of-large-vessel-occlusion-in-suspected-stroke-patients
#8
REVIEW
Kevin J Keenan, Charles Kircher, Jason T McMullan
PURPOSE OF REVIEW: Recent advances in endovascular thrombectomy have made acute ischemic stroke due to a large vessel occlusion more treatable than ever. Rapid access to treatment remains paramount and multiple large vessel occlusion prediction scales have been created to enhance prehospital identification and triage of these patients. This review summarizes the current state of large vessel occlusion prediction scales, proposes a set of ideal scale features, and discusses the future of these scales and prehospital neurological emergency response systems...
May 21, 2018: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/29780924/disseminated-nocardiosis-with-retinal-abscess-in-a-patient-treated-for-bullous-pemphigoid
#9
Sidharth Puri, Amir Hadayer, Andrea Breaux, Charles C Barr
Purpose: To report a case of disseminated Nocardiosis with retinal and intracranial lesions. Observations: A 49-year-old woman immunosuppressed because of treatment given for bullous pemphigoid presented with altered mental status and multiple intracranial lesions on imaging. The patient was found to have multiple retinal lesions in both eyes, including a subretinal abscess in the right eye. The patient underwent brain biopsy, confirming Nocardia farcinica histopathologically and in culture...
June 2018: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29780880/circadian-and-brain-state-modulation-of-network-hyperexcitability-in-alzheimer-s-disease
#10
Rosalind Brown, Alice D Lam, Alfredo Gonzalez-Sulser, Andrew Ying, Mary Jones, Robert Chang-Chih Chou, Makis Tzioras, Crispin Y Jordan, Izabela Jedrasiak-Cape, Anne-Laure Hemonnot, Maurice Abou Jaoude, Andrew J Cole, Sydney S Cash, Takashi Saito, Takaomi Saido, Richard R Ribchester, Kevan Hashemi, Iris Oren
Network hyperexcitability is a feature of Alzheimer' disease (AD) as well as numerous transgenic mouse models of AD. While hyperexcitability in AD patients and AD animal models share certain features, the mechanistic overlap remains to be established. We aimed to identify features of network hyperexcitability in AD models that can be related to epileptiform activity signatures in AD patients. We studied network hyperexcitability in mice expressing amyloid precursor protein (APP) with mutations that cause familial AD, and compared a transgenic model that overexpresses human APP (hAPP) (J20), to a knock-in model expressing APP at physiological levels (APPNL/F )...
March 2018: ENeuro
https://www.readbyqxmd.com/read/29780649/sonographic-demonstration-of-intracranial-hemorrhage-in-a-fetus-with-hydrops-fetalis-due-to-rh-alloimmunization-after-intrauterine-intravascular-transfusion-a-case-report-and-review-of-the-literature
#11
Rauf Melekoglu, Ebru Celik, Hasim Kural
Intrauterine transfusion is the most common and successful intrauterine procedure for the treatment of fetal anemia due to red cell alloimmunization. Fetal intracranial hemorrhage is a very rare complication of intrauterine transfusion in patients with Rh(D) alloimmunization and it has been demonstrated only in a few case reports in the literature. Herein, we described a case of grade IV intraventricular hemorrhage that was diagnosed following the first intrauterine transfusion and reviewed the literature about the fetal intracranial hemorrhage that occurred after intrauterine intravascular transfusion procedure...
2018: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29780296/metal-artifact-reduction-for-orthopedic-implants-brain-ct-angiography-in-patients-with-intracranial-metallic-implants
#12
Leonard Sunwoo, Sun-Won Park, Jung Hyo Rhim, Yeonah Kang, Young Seob Chung, Young-Je Son, Soo Chin Kim
Background: The purpose of this study was to qualitatively and quantitatively evaluate the effects of a metal artifact reduction for orthopedic implants (O-MAR) for brain computed tomographic angiography (CTA) in patients with aneurysm clips and coils. Methods: The study included 36 consecutive patients with 47 intracranial metallic implants (42 aneurysm clips, 5 coils) who underwent brain CTA. The computed tomographic images with and without the O-MAR were independently reviewed both quantitatively and qualitatively by two reviewers...
May 21, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29780259/delivery-of-bevacizumab-by-intracranial-injection-assessment-in-glioma-model
#13
Yu-Xiao Liu, Wen-Jia Liu, Hui-Ru Zhang, Zhi-Wen Zhang
Background: Many reports have indicated that the intravenous administration of bevacizumab produces a number of systemic side effects. Therefore, we investigated the therapeutic effects of intratumoral bevacizumab administration using a glioma animal model. Methods: The glioma cell lines U251 and U87 that carried luciferase were implanted into the brains of mice to develop glioma models. Glioma-bearing mice were treated with bevacizumab intravenously or intratumorally by Alzet micro-osmotic pumps, and the survival time of mice was monitored...
2018: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29780233/spinal-meningeal-melanocytoma-in-a-5-year-old-child-a-case-report-and-review-of-literature
#14
Ahmed M Salah El-Din, Hashem M Aboul-Ela, Mohamed F Alsawy, Ahmed Koheil, Ahmed H Ashry
Background: Meningeal melanocytoma is considered a rare lesion arising from leptomeningeal melanocytes. Nearly two thirds of meningeal melanocytomas were reported in the intracranial compartment and the remaining one third in the spine. Spinal melanocytomas can be extradural or intradural, with extradural variant being more common, and the majority of cases have been single reports. Methods: A 5-year-old male presented with a 4-month history of non-radiating low back pain persistent at rest, with otherwise non-remarkable medical history...
2018: Egypt J Neurol Psychiatr Neurosurg
https://www.readbyqxmd.com/read/29780232/cerebral-arteriovenous-malformations-in-the-era-of-embolization-for-angiographic-cure-a-single-center-experience-in-egypt
#15
Mohamed K Elewa
Background: Embolization for cerebral arteriovenous malformations (AVMs) has evolved in the last decade with evolution in both equipment and material. Embolization targets have expanded to include angiographic cure. Methods: To discuss the technical and management outcomes of our first cerebral AVM case series treated with embolization. The clinical, angiographic, treatment, and outcome variables of consecutive cerebral arteriovenous malformation cases, treated with curative embolization, between January 2011 and June 2017 in one regional center, were retrospectively analyzed...
2018: Egypt J Neurol Psychiatr Neurosurg
https://www.readbyqxmd.com/read/29780229/long-term-follow-up-of-motor-function-deterioration-following-microsurgical-resection-of-middle-third-parasagittal-and-falx-meningioma
#16
Ashraf Ahmad Elzarief, Mohamed Fouad Ibrahim
Background: Incidence of parasagittal meningioma varies in literature; it ranges from 16.8% to 25.6% of intracranial meningioma. Parafalcine meningioma accounts for about 8.5% of intracranial meningioma. Based on their relation to the superior Sagittal sinus and falx, these tumors had been classified into 3 groups; anterior third located between crista galli and coronal suture, middle third located between coronal and lambdoid sutures, and posterior third located posterior to lambdoid suture...
2018: Egypt J Neurol Psychiatr Neurosurg
https://www.readbyqxmd.com/read/29780227/neurophysiologic-tests-screening-cognitive-impairment-in-idiopathic-intracranial-hypertension-patients
#17
Iman A Elbanhawy, Gihan M Ramzy, Mye A Basheer, Diana M Khedr
Background: Idiopathic intracranial hypertension (IIH) is a disorder with increased intracranial pressure of obscure cause. Patients with IIH may suffer from difficulty in thinking or concentrating. This work aimed at highlighting the neurophysiologic suggestions of cognitive impairment in IIH patients. Methods: Twenty patients with IIH-and a similar number of matched control subjects-were examined in this case-control study. The P300 and contingent negative variation (CNV) were performed...
2018: Egypt J Neurol Psychiatr Neurosurg
https://www.readbyqxmd.com/read/29780226/cerebral-border-zone-infarction-an-etiological-study
#18
Tarek Mohammed El-Gammal, Wafik Said Bahnasy, Osama Abd Allah Ragab, Ayman Mohammed Al-Malt
Background: Border zone infarcts (BZI) are ischemic lesions at the junction between two main arterial territories which may be either cortical or internal BZI. Methods: This study was conducted on 76 cerebral BZI patients and 20 healthy control subjects. Patients were divided to group I included 26 internal BZI, group II included 19 cortical BZI and group III included 21 mixed internal/cortical BZI patients. Included subjects were submitted to neurological examination, laboratory investigations, ECG, echocardiogram, brain CT and/or MRI and extra and intracranial blood vessels imaging by duplex and CT angiography...
2018: Egypt J Neurol Psychiatr Neurosurg
https://www.readbyqxmd.com/read/29780223/surgical-outcomes-and-predictors-of-complication-in-elderly-patients-with-meningiomas
#19
Ayman E Galhom, A A Madawi, M M Ellabban
Background: Surgical management of symptomatic meningioma in elderly is still a high-risk surgery due to increased incidence of complication rate. Many scoring systems have been proposed to expect the surgical risk and the outcome.The study tries to assess cranial meningioma surgery in elderly using the Ibañez grade for complication rate and the Geriatric Scoring System (GSS) for the surgical outcome (GSS). Methods: A clinical and radiological data were studied retrospectively in 42 patients with a primary intracranial meningioma at or above the age of 65...
2018: Egypt J Neurol Psychiatr Neurosurg
https://www.readbyqxmd.com/read/29779675/utilization-of-head-ct-during-injury-visits-to-united-states-emergency-departments-2012-2015
#20
Brian J Yun, Pierre Borczuk, Kori S Zachrison, Joshua N Goldstein, Yosef Berlyand, Ali S Raja
INTRODUCTION: Studies have shown increasing utilization of head computed tomography (CT) imaging of emergency department (ED) patients presenting with an injury-related visit. Multiple initiatives, including the Choosing Wisely™ campaign and evidence-based clinical decision support based on validated decision rules, have targeted head CT use in patients with injuries. Therefore, we investigated national trends in the use of head CT during injury-related ED visits from 2012 to 2015. METHODS: This was a secondary analysis of data from the annual United States (U...
May 18, 2018: American Journal of Emergency Medicine
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